192 research outputs found
Caoutchouc-polka : pour piano / par Edouard Croze-Magnan ; [ill. par] E Buval
No full textTitre uniforme : Croze-Magnan, Edouard (18..-19..? ; compositeur). Compositeur. [Caoutchouc-polka. Piano]Polkas (piano) -- +* 1800......- 1899......+:19e siècle:Piano, Musique de -- +* 1800......- 1899......+:19e siècle
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No full textC BIS J
Herrn Peter Baylens, weyland Professors der Philosophie und Historie zu Rotterdam, Historisches und Critisches Wörterbuch (-)
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Des Herrn Maturin Veißiere la Croze Anmerkungen zu diesem Zweyten Bande des Baylischen Historischen critischen Woerterbuchs. ( - )
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Critical role of toll-like receptors in modulating GM-CSF activity in rodent models of colitis
No full textWater temperature modeling in the Garonne River (France)
No full textStream water temperature is one of the most important parameters for water quality and ecosystem studies. Temperature can influence many chemical and biological processes and therefore impacts on the living conditions and distribution of aquatic ecosystems. Simplified models such as statistical models can be very useful for practitioners and water resource management. The present study assessed two statistical models – an equilibrium-based model and stochastic autoregressive model with exogenous inputs – in modeling daily mean water temperatures in the Garonne River from 1988 to 2005. The equilibrium temperature-based model is an approach where net heat flux at the water surface is expressed as a simpler form than in traditional deterministic models. The stochastic autoregressive model with exogenous inputs consists of decomposing the water temperature time series into a seasonal component and a short-term component (residual component). The seasonal component was modeled by Fourier series and residuals by a second-order autoregressive process (Markov chain) with use of short-term air temperatures as exogenous input. The models were calibrated using data of the first half of the period 1988–2005 and validated on the second half. Calibration of the models was done using temperatures above 20 ◦C only to ensure better prediction of high temperatures that are currently at stake for the aquatic conditions of the Garonne River, and particularly for freshwater migrating fishes such as Atlantic Salmon (Salmo salar L.). The results obtained for both approaches indicated that both models performed well with an average root mean square error for observed temperatures above 20 ◦C that varied on an annual basis from 0.55 ◦C to 1.72 ◦C on validation, and good predictions of temporal occurrences and durations of three temperature threshold crossings linked to the conditions of migration and survival of Atlantic Salmon
Effects of interferons α/β on the proliferation of human micro- and macrovascular endothelial cells
No full textSynthetic interferons (IFNs) are used in the treatment of several types of cancer. In addition to an antitumor effect, IFNs show antiangiogenic activity. The aim of this study was to investigate the effects of IFN-α and IFN-β on human micro- and macrovascular endothelial cells in vitro [human micro vascular lung endothelial cells (HMVEC-L) and human umbilical cord endothelial cells (HUVEC)]. By immunohistochemical staining and quantitative reverse transcriptase (RT)-polymerase chain reaction, we studied expression of type I IFN receptors. We evaluated the effects of IFN-α and IFN-β on the proliferation (DNA content), apoptosis (DNA fragmentation by enzyme-linked immunosorbent assay), and cell cycle distribution (flow-cytometric analysis) of endothelial cells. HUVEC and HMVEC-L cells show comparable expression level of the distinct IFN receptor subtypes. Proliferation of HMVEC-L and HUVEC was inhibited by IFN-β (the half maximal inhibitory concentration [IC(50)] = 60 and 90 IU/mL, respectively), but not by IFN-α at a dose up to 1,000 IU/mL. An interesting and unexpected observation was an inhibition of apoptosis by IFN-β. After 72 h of treatment with IFN-β. Cell cycle inhibition occurs in late S-phase in both cell lines. In conclusion, only IFN-β, not IFN-α (10-1,000 IU/mL), has an inhibitory activity on endothelial cell proliferation. Surprisingly, apoptosis was decreased by IFN treatment, whereas inhibition of proliferation is caused by cell cycle arrest in late S-phas
Underway pCO2 in the Southern Ocean of Discovery cruise 74E320041213 during CROZEX
No full textUnderway pCO2 in the Southern Ocean of Discovery cruise 74E320041213 during CROZE
Underway pCO2 in the Southern Ocean of Discovery cruise 74E320041103 during CROZEX
No full textUnderway pCO2 in the Southern Ocean of Discovery cruise 74E320041103 during CROZE
IFN-beta is a highly potent inhibitor of gastroenteropancreatic neuroendocrine tumor cell growth in vitro
No full textIFN-alpha controls hormone secretion and symptoms in human gastroenteropancreatic neuroendocrine tumors (GEP-NET) but it rarely induces a measurable tumor size reduction. The effect of other type I IFNs, e.g., IFN-beta, has not been evaluated. We compared the antitumor effects of IFN-alpha and IFN-beta in BON cells, a functioning human GEP-NET cell line. As determined by quantitative reverse transcription-PCR analysis and immunocytochemistry, BON cells expressed the active type I IFN receptor mRNA and protein (IFNAR-1 and IFNAR-2c subunits). After 3 and 6 days of treatment, IFN-beta significantly inhibited BON cell growth in a time- and dose-dependent manner. IC50 and maximal inhibitory effect on day 6 were 8 IU/mL and 98%, respectively. In contrast, the effect of IFN-alpha resulted significantly in a less potent effect (IC50: 44 IU/mL, maximal inhibition: 26%). IFN-alpha induced only cell cycle arrest, with an accumulation of the cells in S phase. IFN-beta, apart from a more potent delay in S-G2-M phase transit of the cell cycle, also induced a strong stimulation of apoptosis, evaluated by flow cytometry (Annexin V and 7-AAD) and measurement of the DNA fragmentation. Besides, only IFN-beta severely suppressed chromogranin A levels in the medium from BON cells after 6 days of treatment. In conclusion, IFN-beta is much more potent, compared with IFN-alpha, in its inhibitory effect on GEP-NET cell proliferation in vitro through the induction of apoptosis and cell cycle arrest. Further studies are required to establish whether IFN-beta has comparable potent tumor growth inhibitory effects in vivo
A potential tool in the battle against gastroenteropancreatic neuroendocrine tumors: Interferon-beta
No full textEffet rétroactif de la jurisprudence : le retour
No full textInternational audience(Civ. 1re, 31 janv. 2008, D. 2008. 1448, note A. Aynès ; JCP E 2008. 1742, note F. Buy ; Procédures, mai 2005. comm. 144, H. Croze ; JCP E 2008. II. 10074, note H. Slim ; LPA 10 avr. 2008, n° 73, p. 18, note J. Lasserre-Capdeville
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