1,687 research outputs found
Disrupted nighttime sleep and sleep instability in narcolepsy
No full textSTUDY OBJECTIVES: This review aimed to summarize current knowledge about disrupted nighttime sleep (DNS) and sleep instability in narcolepsy, including self-reported and objective assessments, potential causes of sleep instability, health consequences and functional burden, and management. METHODS: One hundred two peer-reviewed publications from a PubMed search were included. RESULTS: DNS is a key symptom of narcolepsy but has received less attention than excessive daytime sleepiness and cataplexy. There has been a lack of clarity regarding the definition of DNS, as many sleep-related symptoms and conditions disrupt sleep quality in narcolepsy (eg, hallucinations, sleep paralysis, rapid eye movement sleep behavior disorder, nightmares, restless legs syndrome/periodic leg movements, nocturnal eating, sleep apnea, depression, anxiety). In addition, the intrinsic sleep instability of narcolepsy results in frequent spontaneous wakings and sleep stage transitions, contributing to DNS. Sleep instability likely emerges in the setting of orexin insufficiency/deficiency, but its exact pathophysiology remains unknown. DNS impairs quality of life among people with narcolepsy, and more research is needed to determine its contributions to cardiovascular risk. Multimodal treatment is appropriate for DNS management, including behavioral therapies, counseling on sleep hygiene, and/or medication. There is strong evidence showing improvement in self-reported sleep quality and objective sleep stability measures with sodium oxybate, but rigorous clinical trials with other pharmacotherapies are needed. Treatment may be complicated by comorbidities, concomitant medications, and mood disorders. CONCLUSIONS: DNS is a common symptom of narcolepsy deserving consideration in clinical care and future research. CITATION: Maski K, Mignot E, Plazzi G, Dauvilliers Y. Disrupted nighttime sleep and sleep instability in narcolepsy. J Clin Sleep Med. 2022;18(1):289-304
Notion of Conflict : A Selection of Contemporary Canadian Art
No full textMignot discusses the work of the 13 Canadian artists who took part in the commemoration of the end of World War II in the Netherlands. Each work is accompanied by an artist's statement. 4 bibl. ref
Os sentidos atribuídos pelas crianças aos seus cadernos escolares
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Educação, Programa de Pós-Graduação em Educação, Florianópolis, 2013.Durante o passar dos séculos, os cadernos escolares vêm sofrendo um processo de naturalização. Todavia, o que se percebe é que, ainda que naturalizados, o uso deste material não é natural para as crianças, que cotidianamente demonstram suas dificuldades ao manusear este objeto. Este processo de naturalização, associado aos usos deste material nas salas de aula dos dias de hoje é que nos motiva a pensar e discutir, acerca dos sentidos atribuidos pelas crianças aos seus cadernos escolares. Assim, esta pesquisa tem como objetivo principal investigar os usos e os sentidos atribuídos pelas crianças, no primeiro ano do Ensino Fundamental, aos seus cadernos escolares. Deste modo, este estudo de cunho qualitativo e de tipo etnográfico embasou-se nos seguintes procedimentos metodológicos: a observação participante do processo de ensino-aprendizagem; encontros informais com os alunos e com a professora; intervenção; análise de documentos (cadernos escolares); entrevista semiestruturada; e diário de pesquisa. A pesquisa foi realizada em duas etapas: a primeira delas consistiu no levantamento bibliográfico, realizado com o intuito de mapear os estudos já desenvolvidos sobre a temática e contextualizar historicamente a questão problematizada; e a segunda etapa consistiu na pesquisa empírica realizada em duas turmas de primeiro ano de uma escola municipal de Florianópolis, na qual foi observada uma turma no ano de 2012.2 e outra turma no ano de 2013.1. Foram realizadas entrevistas semiestruturadas com as crianças e com a professora regente de cada turma. Os dados foram analisados a partir da Análise de Conteúdo, tendo como referência as ideias de Bardin (2011). Os dados analisados mostram o quanto os sentidos atribuídos a este material pelos professores diferem dos sentidos atribuídos a este material pelas crianças. Estes indicativos revelam o quanto o uso do caderno escolar ainda é um tema que necessita de reflexão, discussão e planejamento, para que, de fato, este material atenda a finalidades pedagógicas.Abstract : During the centuries, the notebooks are undergoing a process of naturalization. However, what we see is that even naturalized, the use of this material is not natural for children who daily demonstrate their difficulties when handling this material. This naturalization process together the use of these materials in the classroom of the day today is what motivates us to think and discuss about the meanings attributed by the children at their school notebooks. Thus, this research aims at investigating the uses and meanings attributed by the children in the first year of primary school to their school notebooks. Thus, this study of a qualitative and ethnographic based on the following instruments: participant observation of teaching and learning, informal meetings with students and with the teacher, intervention, analysis of documents (notebooks), semi-structured interviews and diary research. The research was conducted in two stages: the first is the literature review conducted in order to map the studies already undertaken on the theme and contextualize historically problematic issue and the second step is the empirical research carried out in two groups of first year of a municipal school in Florianópolis in which there was a class in the year 2012.2 and another class in the year 2013.1. Were conducted semi-structured interviews with the children and with the teacher every class regent. Data were analyzed using the content analysis, with reference to the ideas of Bardin (2011). The data analyzed show us how the meanings attributed to this material by teachers differ from the meanings attributed to this material by children. These indicators show how the use of school notebook is still a topic that needs reflection, discussion and planning, so that in fact this material meets the educational purposes
Ryhiner-Kartensammlung / 30 Carte générale de la province de Languedoc : levée par ordre et aux fraix des etats, président en iceux, Monseigneur Arthur Richard Dillon, archevêque et primat de Narbonne président ne desdits etats commandeur de l'Ordre du St. Esprit
No full textlevée sous la direction des MM.rs [César François] Cassini [Etienne Mignot?] de Montigny et [Jean Rodolphe] Perronet ; reduite sur l'echelle d'une ligne pour 500. toises par le Sr. Capitaine ingénieur géo. du ro
Charles Mozin, 1806-1862. Musée de Trouville, Musée E. Boudin Honfleur, 1988. 165 nos, 102 ill. noir et couleurs.
No full textMignot Claude. Charles Mozin, 1806-1862. Musée de Trouville, Musée E. Boudin Honfleur, 1988. 165 nos, 102 ill. noir et couleurs.. In: Revue de l'Art, 1989, n°83. p. 114
Margherita Azzi Visentini, La villa in Italia, Quattrocento e Cinquecento. Milan, Electa, 1995. 364 p. ill. en n. et bl. et en coul.
No full textMignot Claude. Margherita Azzi Visentini, La villa in Italia, Quattrocento e Cinquecento. Milan, Electa, 1995. 364 p. ill. en n. et bl. et en coul.. In: Revue de l'Art, 1997, n°115. pp. 71-72
Charles Mozin, 1806-1862. Musée de Trouville, Musée E. Boudin Honfleur, 1988. 165 nos, 102 ill. noir et couleurs.
No full textMignot Claude. Charles Mozin, 1806-1862. Musée de Trouville, Musée E. Boudin Honfleur, 1988. 165 nos, 102 ill. noir et couleurs.. In: Revue de l'Art, 1989, n°83. p. 114
The Lovers
No full textMcEvilly's diaristic, 28-"chapter" account of Abramovic's and Ulay's respective performance-walks toward each other along the Great Wall of China forms the backbone for this catalogue-cum-travelogue; he discusses the history of the artists and his relationship to them, the spiritual and aesthetic aspects of walking, and the adventures and misadventures of preparing for and carrying out the trip. He draws from both European authors and Chinese poets to enhance his perspective on the subject. Mignot contextualizes the piece within the artists' career and gives an account of the exhibition; two sections are dedicated to photos and writings of each artist inspired by this experience. Biographical notes. Circa 90 bibl. ref
The Arts for Television
No full textBringing together the works of 102 artists, this exhibit promotes television as a creative medium. Works and essays are classified under the following headings: image, theatre, literature, dance, music and television. Includes a brief history of art and television as well as an index of artist's names. Bibl. 2p
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