6,412 research outputs found
Consultant to the National Cancer Institute -- 1967-69 -- United States Public Health Service -- letter, 1968-06-11
No full textLetter from Duff, James T. to Sabin, Albert B. dated 1968-06-11.Sabin Collection Fair Use Policy</a
Then come dearest maiden while fair shines the moon [first line of chorus]
No full textstrophic with choruspiano and voiceJohns Hopkins University, Levy Sheet Music Collection, Box
114, Item 179Poetry by T. Duff. Music by Charles T. Sykes
Then come dearest maiden while fair shines the moon [first line of chorus]
No full textstrophic with choruspiano and voiceJohns Hopkins University, Levy Sheet Music Collection, Box
114, Item 179Poetry by T. Duff. Music by Charles T. Sykes
Quantum discontinuity for massive spin-3/2 with a Lambda term
No full textM.J. Duff, James T. Liu, H. Sat
Grace and Truth Vindicated, Or The Way to Heaven Manifested, From Scripture and Experience / By John Green, Late Curate of Thurnscoe, in Yorkshire
No full textVorlageform der Veröffentlichungsangabe: London: Printed by H. Cock, in Bloomsbury-Market; for the Author at his House in Great St. Andrew's Street, near the Seven Dials; and fold by G. Woodfall, near Charing-Cross; T. Trye, near Grey's- Inn-Gate; and T. James, under the Royal Exchang
Sketch of the Duff's Groupe [cartographic material] : discovered September 25, 1797 by Capt. James Wilson /
No full textMap of the Duff Is. group, Solomon Isls., with relief shown by hachures.; Coastal profiles: View of Treasurers Island -- View of Disappointment Island.; Plate from: A missionary voyage to the Southern Pacific Ocean, performed in the years 1796, 1797, 1798, in the ship Duff, commanded by Captian James Wilson ...; Ferguson, J.A. Bibliography of Australia, 301; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.map-rm2493
Cognition in t(1;11) translocation carriers and patients with psychotic disorders
No full textDeficits in a number of cognitive domains have been associated with core symptoms of
schizophrenia, including working memory, attention, motor skills, reaction time, episodic
memory and executive function. Bipolar Disorder is also associated with cognitive impairment;
however the level of impairment appears to be less severe than that seen in schizophrenia.
A translocation (t(1;11)) containing the Disrupted-in-Schizophrenia 1 (DISC1) gene has been
found to be highly associated with schizophrenia, bipolar disorder and major depressive
disorder. As such, this gene has been the focus of much research and to date DISC1 has been
found to be associated with brain development, brain structure and the glutamate system - all
key factors in current models of schizophrenia and affective disorders.
The aim of this PhD is to identify cognitive domains that are differentially impaired or
unimpaired in a large Scottish family, some of whom carry this rare DISC1 variant, a balanced
translocation (t (1;11) (q 42; q14.3)), that segregates with schizophrenia and affective disorders,
as well as psychiatric patients with schizophrenia and bipolar disorder and healthy control
subjects.
All participants have undergone standardised cognitive assessments to measure premorbid I.Q.
(NART), current I.Q. (WASI) verbal memory, working memory, verbal fluency, processing
speed, motor skills, executive function (BACS) and selected CANTAB tasks to assess simple
and five-choice reaction time. Polygenic risk profile scores and self-report questionnaire data
have also been investigated.
Results indicate an impact of the DISC1 t(1;11) translocation on general intelligence and
attention and processing speed. Significant differences were also identified between DISC1 t(1;11) carriers and non-carriers on
self-report questionnaire data. Mean scores for polygenic risk for bipolar disorder were
significantly different between DISC1 t(1;11) carriers and non-carriers and polygenic risk for
schizophrenia was significantly associated with symptom severity, as measured by the Positive
and Negative Symptom Scale (PANSS).
Within the patient groups, a measure of processing speed (the token motor task) was found to
be significantly different between those with schizophrenia and bipolar disorder and there was
also a trend for attention and processing speed. As expected, I.Q. was significantly different
between patients and control participants. Clinical ratings were significantly associated with
neuropsychological and self-report measures. Polygenic risk for major depressive disorder was
found to be significantly associated with impaired general intelligence (current IQ) and slowed
reaction time in patients who were not currently depressed, suggesting there may be genetic
risk markers in this population which impact on cognition. This is a novel finding and further
suggests the possibility of a biological component related to the genetics of depression.
In conclusion, and in line with the literature, psychosis has a negative impact on cognition with
reduced performance across several neuropsychological tasks between patient groups, with
schizophrenia patients performing worse than patients with bipolar disorder and both patient
groups performing worse than healthy control participants. Cognition is markedly more
impaired in DISC1 t(1;11) translocation carriers and especially in those with psychosis. The
DISC1 t(1;11) translocation and psychosis may therefore confer a “double hit” on cognition -
in addition to psychosis itself - which is known to impair cognitive function, significantly
increasing the level of cognitive impairment and increasing the risk for psychosis in general
A critical comparison of William James and Søren Kierkegaard on religious belief
No full textThis thesis is a critical comparison of the accounts of religious belief proposed byWilliam James and Søren Kierkegaard. Both James and Kierkegaard greatly emphasizethe subjective aspects of religious belief. In view of this fact, surprisingly littlecomparative work has been done in this area. I contribute to this literature in two ways.Firstly, I make a brief assessment of what James knew of Kierkegaard’s work.Secondly, I draw four comparisons between Kierkegaard and James. In Chapter One Iexamine the claim that Kierkegaard proposes a pragmatist account of faith of the kindthat James sets out in his essay The Will To Believe. I argue that this claim rests on amisunderstanding of Kierkegaard’s argument that to have faith is to take a risk. In thefollowing chapter I discuss James’s and Kierkegaard’s views on formal proofs for theexistence of God. Both philosophers reject the notion that faith can be based on suchproofs. I distinguish between their positions, and argue in favour of Kierkegaard’s. Inthe third chapter I compare Kierkegaard’s and James’s accounts of religious experience.James views religious experiences as a special kind of evidence for the existence ofGod. For Kierkegaard it is a mistake to view religious experiences as evidence. Suchexperiences should be understood in relation to the concept of religious authority. In thefinal chapter I examine Kierkegaard’s conception of faith as a life-view. I argue that forKierkegaard a life-view is a fundamental perspective on one’s existence. I compare thisconception with James’s concept of philosophical temperament and in relation to hisdiscussion of the sick soul
Polyphony and the anxiety of influence in the fiction of Henry James
No full textJames's fiction, especially in the Middle Phase, centres
on the figure of the artist and is characterized by, the two
interrelated aspects which previous criticism has largely
overlooked: the Bakhtinian 'polyphonic' -creation of
'author-thinkers'; and the conflict between ephebes and
precursors, for which Harold-Bloom's concept of 'the-anxiety of
influence' is the most illuminating model. Polyphony is the
narrative mode, and influence is the intra-artistic, theme.
These, as the Introduction to the thesis makes clear, are
rehearsed in James's inaugural novel, Roderick Hudson. Rowland
Mallet is an author-thinker, and his failure is caused by
authorial limitations. His monologism -is impaired by his
mistaking empathy for the authorial sympathy. Likewise,
Hudson's failure does not arise from a mercurial temperament,
but from a polyphonic shortcoming: not possessing the power of
fiction to contain the fiction of power in, his mentor. And the
relationships among the three artists - Gloriani, Hudson and
Singleton - perfectly exemplify the Bloomian-theme. It is these
two concepts, polyphony and influence, which are the major
preoccupation in the Middle Phase; as, the works chosen
demonstrate. These are a novella, a novel, and a number of
short stories all of which have been unjustifiably neglected.
Chapter One, on The Aspern Papers, argues that Tina Bordereau,
far from being, the artless victim seen by many critics,
actually challenges and defeats the narrator by the very form
of her narrative. Her 'realist' discourse undermines his
language of 'romance', and shows up its internal unstability.
Chapter Two is an extensive study of the critical reception of
The Tragic Muse. The most common areas of critical attention
have been its contemporary topicality, its relation to previous
novels on similar themes, and the possible genealogy of Gabriel
Nash. Those have all missed the core of the work. - Chapter Three
demonstrates how polyphony and the anxiety of influence make
the novel what it really is. Influence arises from the
juxtaposition of, and the wrestling between, artistic ephebes
and their precursors (Nick and Nash,, Miriam and Madame Carre).
The dialogic quality defined by Bakhtin is crucial to the
proper, and even-handed, characterization of all, the conflicts
in the novel. And since most of James's tales in the eighties
and nineties -are about 'masters - and acolytes, the anxiety of
influence remains central. Chapter Four is a study of 'The
Author of Beltraffiol' and 'The Lesson of the Master'. Again the
characters' manipulations are a crucial focus in a way that
G6rard Genette's terminology helps to illuminate. The fact that
the ephebe is the author-thinker emphasizes the inextricability
of the Bakhtinian and the Bloomian in James. Just as
polyphony offers a different focus for explicating the poetics
of James's fiction; so the ephebal conflict provides the basis
for a fresh perception of James's own artistic struggle
Predicting Duff and Woody Fuel Consumption in Northern Idaho Prescribed Fires
No full textExperimental burns were conducted on 36 plots in mixed conifer logging slash in northern Idaho to investigate consumption of duff and woody fuel. Fires were conducted in spring and fall, in YUM (yarded unmerchantable material) and non-YUM dearcuts and seed-tree cuts. Preburn duff depth averaged 3.8 cm and consisted of a shallow layer of decomposing litter, averaging 2 cm, interspersed with deep pockets of rotten wood averaging 13 cm. Preburn total woody fuel quantities ranged from 63 to 193 t/ha. Regression relationships between fuel consumption and fuel characteristics were developed. Duff depth reduction was related to preburn duff depth and to a lesser extent, duff moisture content. Percent duff consumption and mineral soil exposure were related negatively to duff moisture and positively to large fuel (diameter \u3e 7.6 cm) diameter reduction. Diameter reduction of large fuel pieces was positively related to preburn diameter and negatively related to measured moisture content. Consumption of rotten material was greater than that of sound material. These relationships were compared to other empirical fuel consumption models and a theoretical model in predicting our fuel consumption. The relationships presented here can be used to predict duff and woody fuel consumption from prescribed burning in logging slash in the mixed conifer type of the northern Rocky Mountains
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