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Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Avaliação do efeito local da sinvastatina associado ao fosfato de cálcio bifásico na regeneração de defeitos ósseos pré-estabelecidos na calvária de ratos
Get PDFTese (doutorado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, 2016.Objetivo: O propósito deste estudo foi observar histologicamente em defeitos criados em calvária de ratos, o potencial da aplicação local da sinvastatina na estimulação da formação óssea e avaliar os efeitos da asociação da sinvastatina com dois tipos de carreador: Fosfato de cálcio (BoneCeramic®) ou Esponja de colágeno (CollaTape® ) na neoformação óssea. Materiais e métodos: Defeitos bilaterais foram obtidos nas calvárias de 15 ratas jovens. Esses defeitos tinham 5 mm de diâmetro e foram divididos em 5 grupos de acordo com o tipo de tratamento recebido: grupo 1(C) – controle, sem tratamento; grupo 2 (BC) - tratados com 14 mg BoneCeramic®; grupo 3 (BCS) - tratados com 14 mg de BoneCeramic® combinado com 0,1 mg de sinvastatina em solução alcoólica; grupo 4 (EC) - tratados com esponja de colágeno (CollaTape®); e grupo 5 (ECS) - tratados com esponja de colágeno combinada com 0,1 mg de sinvastatina em solução alcoólica. Após 8 semanas os animais foram sacrificados e as regiões dos defeitos submetidas à coloração Hematoxilina/Eosina (HE), seguida de avaliação histomorfométrica. Além disso, no grupo (BCS) foram realizadas análises histoquímica por tricromio de Masson e picrosirius red para caracterizar o tecido neoformado. Resultados:. Os resultados histológicos mostraram que a utilização local da sinvastatina favoreceu à neoformação óssea. O melhor resultado quanto à neoformação óssea foi obtido no grupo tratado com BCS, seguido do grupo BC. No grupo tratado com BCS a quantidade de neoformação óssea foi maior do que no grupo tratado com BC, ECS, EC, e C, e essas diferenças foram estatisticamente significativas(BCS 12,71 ± 1,21; BC 9,04 ± 0,86; ECS 2,25 ± 0,61, EC 0,91 ± 0,86 e C 0,00 ± 0,00) Não houve diferenças na neoformação óssea nos grupos ECS, EC e C . Além disso, a análise histoquímica do grupo (BCS), evidenciou a presença de neoformação óssea com a neoformação de tecido osteóide imaturo pelo tricrômio de Masson, além de colágeno organizado tipo I ao redor das partículas do BoneCeramic. Conclusão: Os resultados sugerem que a sinvastatina localmente administrada na concentração pré-estabelecida de 0,1mg, quando associada ao Fosfato de Cálcio Bifásico (BoneCeramic®) osteocondutor, resultou em maior neoformação óssea, comparado ao uso do Fosfato de Cálcio (BoneCeramic®) isoladamente, ou a sinvastatina associado à esponja de colágeno. Portanto a combinação de sinvastatina e BoneCeramic® pode ter um grande potencial no tratamento de defeitos ósseos.OBJECTIVE: The objective of the present study was to examine the potential of locally applied simvastatin on the induction of bone formation and to evaluate the combination of simvastatin with two different carriers: biphasic calcium phosphate (BoneCeramic®) or collagen sponge on stimulation of bone formation. Methods: Thirty defects of 5mm in diameter were created bilaterally with a trephine bur in the calvariae of fifteen Wistar rats. The defects were divided into 5 groups: group 1 - control, no treatment; group 2 (BC) treated with 14mg of BoneCeramic®; group 3 (BCS) treated with 14mg of BoneCeramic® + 0.1mg simvastatin in alcoholic solution; group 4 (EC) treated with a collagen sponge (CollaTape®); and group 5 (ECS) treated with a collagen sponge + 0.1mg simvastatin in alcoholic solution. After eight weeks the animals were euthanized and their calvariae were histologically processed. Hematoxylin and eosin-stained sections were subjected to histological and histomorphometrical analyses. The area of newly formed bone was calculated and compared between groups. Furthermore, the newly formed tissue in group BCS was histochemically analyzed by Masson and picrosirius red satinings to better characterize this tissue. Results: The histological findings showed that the local application of simvastatin induced bone neoformation. The greater amount of a bone-like tissue was formed around the carrier in group 3 (BCS) followed by group 2 (BC). In group BCS, the amount of newly formed bone was greater than groups BC, ECS, EC, and C and these differences were statiscally significant (BCS 12,71 ± 1,21; BC 9,04 ± 0,86; ECS 2,25 ± 0,61, EC 0,91 ± 0,86 e C 0,00 ± 0,00). There was no difference among groups ECS, EC and C. The histochemical analyses of the newly formed tissue from group BCS showed the presence of an osteoid tissue, as shown by the Masson’s trichrome staining. Besides, the presence of organized type I collagen was evidenced around the BoneCeramic particles. Conclusions: The results suggest that locally applied simvastatin at a concentration of 0,1mg combined with BoneCeramic® induced significantly greater amounts of newly formed bone as compared with BoneCeramic® alone or simvastatin combined with collagen sponge. Therefore, the combination of simvastatin and BoneCeramic® and has great potential for the healing of bone defects.Faculdade de Ciências da Saúde (FS)Programa de Pós-Graduação em Ciências da Saúd
Estudo do efeito local da sinvastatina na neoformação óssea de defeitos na calvária de ratos
Get PDFDissertação (mestrado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, 2013.Objetivo: O propósito deste estudo foi observar os efeitos da aplicação local da sinvastatina na estimulação da formação óssea em defeitos criados em calvária de ratos. Além disso, comparar os efeitos entre combinação da sinvastatina com o BoneCeramic® (carreador cerâmico) ou CollaTape® (carreador colágeno) na neoformação óssea, para identificar o melhor carreador para esta droga. Materiais e métodos: Defeitos bilaterais foram obtidos nas calvárias de 15 ratas jovens. Esses defeitos tinham 5 mm de diâmetro e foram divididos em 5 grupos de acordo com o tipo de tratamento recebido: grupo 1 – controle, sem tratamento; grupo 2 (BC) - tratados com 14 mg BoneCeramic®; grupo 3 (BCS) - tratados com 14 mg de BoneCeramic® combinado com 0,1 mg de sinvastatina em solução alcoólica; grupo 4 (EC) - tratados com esponja de colágeno (CollaTape®); e grupo 5 (ECS) - tratados com esponja de colágeno combinada com 0,1 mg de sinvastatina em solução alcoólica. Após 2 semanas da cirurgia os defeitos ósseos foram submetidos a uma avaliação por MicroCT in vivo e com 8 semanas os animais foram sacrificados e as regiões dos defeitos submetidas à avaliação histomorfométrica. Resultados: Os resultados do MicroCT mostraram que ambos os grupos tratados com BC e BCS mostraram um volume ósseo (VO) superior comparados aos demais grupos (EC, ECS e C), (BC 16,76 ± 9,39; BCS 12,47 ± 7,38; EC 0,00 ± 0,01; ECS 1,00 ± 0,19 e C 0,45 ± 0,64). Os grupos tratados com EC e ECS mostraram resultados semelhantes ao controle (C) nesse período de avaliação. Os resultados histológicos mostraram que a utilização local da sinvastatina favoreceu à neoformação óssea. O melhor resultado quanto à neoformação óssea foi obtido no grupo tratado com BCS, seguido do grupo BC, e mínima ou nenhuma neoformação óssea foi observada nos grupos ECS, EC e C (BCS 12,71 ± 1,21; BC 9,04 ± 0,86; ECS 2,25 ± 0,61, EC 0,91 ± 0,86 e C 0,00 ± 0,00). A diferença na quantidade de osso neoformado entre o grupo tratado com BCS e os demais grupos avaliados foi estatisticamente significativa. No grupo tratado com BCS a quantidade de neoformação óssea foi maior do que no grupo tratado com BC somente e ECS, e essas diferenças foram estatisticamente significativas. Conclusão: Por meio deste estudo conclui-se que a sinvastatina administrada de forma local favorecer a neoformação óssea. A maior quantidade de osso neoformado deve ser esperada quando um carreador cerâmico (BoneCeramic®) for utilizado em combinação com a sinvastatina na concentração utilizada no presente estudo (0,1mg). ______________________________________________________________________________________ ABSTRACTObjectives: The objective of the present study was to examine the effects of local application of one of the statins (simvastatin) on bone formation in rat calvaria bone defects. Furthermore, the effects of the combination of simvastatin with BoneCeramic® (ceramic carrier) or CollaTape® (collagenous carrier) on bone formation were compared to identify a better carrier for the drug. Materials and Methods: Bone defects were created bilaterally on the calvaria of fifteen Wistar rats. The defects were 5 mm in diameter and were divided into 5 groups, according to the treatment performed: group 1 - control, no treatment; group 2 (BC) - treated with 14 mg of Bone Ceramic; group 3 (BCS) - treated with 14 mg of Bone Ceramic combined with 0,1 mg of simvastatin in alcoholic solution; group 4 (EC) - treated with collagen sponge (Colla Tape); and group 5 (ECS) - treated with collagen sponge combined with 0,1 mg of simvastatin in alcoholic solution. Two weeks after surgery, the bone defects were subjected to in vivo MicroCT analysis and after 8 weeks all animals were sacrificed and histomorphometrical analyses of the defects were performed. The results of the MicroCT demonstrated that the defects of both groups treated with BC and BCS exhibited a bone volume (BV) greater than the the defects of the other groups (EC, ECS, C): (BC 16,76 ± 9,39; BCS 12,47 ± 7,38; EC 0,00 ± 0,01; ECS 1,00 ± 0,19 e C 0,45 ± 0,64). The groups treated with EC and ECS showed results similar to the control (C) at this time-point. The histological findings demonstrated that local simvastatin application induced bone formation. The greater amount of bone formation was observed in the defects treated with BCS, followed by BC, and minimal to no bone formation was observed in the defects of the other groups (ECS, EC, and C): (BCS 12,71 ± 1,21; BC 9,04 ± 0,86; ECS 2,25 ± 0,61, EC 0,91 ± 0,86 e C 0,00 ± 0,00). The difference on the amount of newly formed bone in the group treated with BCS was statistically significant as compared with the other groups. In the BCS-treated group, the amount of newly formed bone was greater than in the BC- and ECS-treated groups, and the differences were statistically significant. Conclusion: The results of the present study indicate that local administration of simvastatin induces bone formation. The greater amount of newly formed bone should be expected when a ceramic carrier (Bone Ceramic) is used in combination with simvastatin in the concentration applied in the present study (0,1mg).Faculdade de Ciências da Saúde (FS)Programa de Pós-Graduação em Ciências da Saúd
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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