861 research outputs found
Foreword to The Organic Grower
No full textAudrey Windram is a living treasure of Australian organics. She has been ‘fighting the good fight’ to advance the cause of organics for the best part of half a century. When it comes to organics, Audrey leads by example. She has been living the organic life, variously as an organics pioneer, producer, evangelist, educator and author, all the while ‘practising what she preaches’ and preaching in the most gentle of ways. It is a delight to commend Audrey Windram’s latest book The Organic Grower on the fortieth anniversary of the publication of her first organics book. Organic Gardening originally appeared in 1975 as a Rigby Instant Book. It was a mass-market book distributed throughout Australia. The organics enterprise must continue to draw strength from the validity of its foundational premises and continue the fight which Lord Northbourne warned in 1940 may be a fight lasting “for many decades, perhaps for centuries”. In The Organic Grower Audrey Windram brings together four publications, Organic Gardening, the two volumes of Meet the Organic Farmer, together with Ways of Being Organic. Enjoy it
Audrey and Bill a romantic biography of Audrey Hepburn & William Holden
No full text"Here for the first time is the complete, captivating story of an on-set romance that turned into a lifelong love story between silver screen legends Audrey Hepburn and William Holden. In 1954, Hepburn and Holden were America's sweethearts. Both won Oscars that year and together they filmed Sabrina, a now-iconic film that continues to inspire the worlds of film and fashion. Audrey & Bill tells the stories of both stars, from before they met to their electrifying first encounter when they began making Sabrina. The love affair that sparked on-set was relatively short-lived, but was a turning point in the lives of both stars. Audrey & Bill follows both Hepburn and Holden as their lives crisscrossed through to the end, providing an inside look at the Hollywood of the 1950s, '60s, and beyond. Through in-depth research and interviews with former friends, co-stars, and studio workers, Audrey & Bill author Edward Z. Epstein sheds new light on the stars and the fascinating times in which they lived"-
Audrey Niffenegger @ The Cleveland Public Library
No full textAuthor and dedicated book artist Audrey Niffenegger autographs one of her books at an appearance she made as part of Octavofest 2011 at the Cleveland Public Library. Audrey Niffenegger is the acclaimed author of The Time Traveler\u27s Wife and Her Fearful Symmetry as well as the graphic novel, The Night Bookmobile. She is also a co-founder of the Columbia College Center for Book and Paper Arts in Chicagohttps://engagedscholarship.csuohio.edu/octavofest_gallery/1002/thumbnail.jp
Audrey Niffenegger @ The Cleveland Public Library
No full textAuthor and dedicated book artist Audrey Niffenegger autographs one of her books at an appearance she made as part of Octavofest 2011 at the Cleveland Public Library. Audrey Niffenegger is the acclaimed author of The Time Traveler\u27s Wife and Her Fearful Symmetry as well as the graphic novel, The Night Bookmobile. She is also a co-founder of the Columbia College Center for Book and Paper Arts in Chicagohttps://engagedscholarship.csuohio.edu/octavofest_gallery/1002/thumbnail.jp
Regulation of proNGF processing and its effects on p75NTR-mediated cell death following seizure
No full textNerve growth factor (NGF) has been known to play critical roles in neuronal survival and differentiation during development. Recent studies have
discovered that its immature form, proNGF, is a ligand for the p75 neurotrophin receptor (p75NTR). proNGF binding to p75NTR activates apoptotic signaling, and
this binding occurs with a five-fold higher affinity than that of mature NGF (Lee et al., 2001). This binding preference, along with the increased prevalence of
proNGF after injury (Harrington et al., 2004), creates a cellular environment susceptible to cell death; thus, the balance between levels of pro- and mature NGF may be a key factor in determining whether a neuron lives or dies (Lee et al., 2001; Volosin et al., 2006). Using both in vitro and in vivo methods, this thesis examined the mechanisms that regulate the extracellular processing of proNGF and the consequences of that processing on p75NTR-mediated cell death following injury. The results discussed here demonstrate that 1) proNGF binding leads to cell death via the p75NTR signaling pathway; 2) after injury, proNGF is upregulated and preferentially secreted in a functional manner capable of
activating the p75NTR-mediated apoptotic pathway; 3) the enzymes plasmin and MMP7 extracellularly cleave proNGF, 4) after injury, plasmin activation and
MMP7 activity are reduced, leading to increased proNGF-induced apoptosis, and 5) restoring plasmin or MMP7 activity following brain injury reduces proNGF
levels and consequently, p75NTR-mediated apoptosis. Overall, these data suggest that increased cell death following injury may be mediated in part by a
change in the balance between extracellular proNGF and the activity of its processing enzymes, leading to increased cell death via p75NTR.Ph.D.Includes bibliographical referencesIncludes vitaby Audrey P. L
Contribution to the study of structure-property relationships of sugar-based amphiphilic molecules
No full textDans le contexte du développement durable, l’'utilisation des ressources renouvelables, biodégradable et peu toxique, est particulièrement recherchée. En particulier, la littérature montre que les molécules amphiphiles biosourcées avec une tête sucre, type glycolipides, sont d'excellents candidats pour substituer les tensioactifs pétrochimiques actuellement utilisés massivement en formulation. Pour limiter le criblage expérimental et orienter le choix des synthèses de telles molécules, une démarche prédictive à partir de l'analyse de la structure moléculaire permettrait d'anticiper les propriétés des molécules amphiphiles et d'identifier celles répondant à des propriétés spécifiques recherchées. L'objectif des travaux de thèse est de développer une méthodologie via la synthèse à façon avec modification graduelle de la structure, la caractérisation et l'analyse systématique de glycolipides, dans le but d'identifier des liens pertinents entre leurs propriétés amphiphiles et leurs caractéristiques structurales. Les données expérimentales générées doivent permettent d'établir une base de données comparables et fiables, nécessaire pour le développement de modèles 1 prédictifs. Les résultats ont mis en évidence l'influence significative de certains paramètres de structure sur j les propriétés physico-chimiques, avec des tendances claires, autrement difficiles à observer à partir des données globales non-comparables de la littérature. Ce travail a également démontré l'importance de prendre en considération le comportement des molécules amphiphiles dans l'eau, via la connaissance de leur diagramme de phase, afin de définir sans ambiguïté certaines propriétés telles que la CMC.In the context of sustainable development, the use of biodegradable and low toxic renewable resources is particularly important. ln particular, the literature shows that the bio-based amphiphilic molecules with a sugar head, or the glycolipids, are excellent substitutes of the petrochemical surfactants used massively in current formulations. To limit the experimental screening and to orient the choice of the syntheses of such molecules, a predictive approach based on the analysis of the molecular structure would make it possible to anticipate the properties of the amphiphilic molecules and to identify those with specific properties. The objective of this work is to develop a methodology through systematic syntheses, characterizations and analyses of glycolipids with gradual structural modifications, with the aim of identifying relevant links between heir amphiphilic properties and their structural characteristics. The obtained experimental data should make it possible to establish a comparable and reliable database, necessary for the development of predictive models. The results showed the significant influence of some structural parameters on the physico-chemical properties with clear trends, which are otherwise difficult to observe by using the non-comparable data collected from the literature. This work also demonstrated the importance of considering the behavior of amphiphilic molecules in water, through knowledge of their phase diagram, which allows for the unambiguous definition of certain properties like the CMC
Bio-based surfactants application for remediation of soils polluted by hydrocarbons
No full textLa compréhension du transport et des interactions de tensioactifs biosourcés en milieu poreux présente un grand intérêt dans les applications environnementales, en particulier pour le contrôle du procédé de dépollution des sols par lavage. L’objectif de ces travaux de thèse est d’étudier le rôle de l’hétérogénéité physique et de l’hydrodynamique du milieu ainsi que de l’impact des propriétés des molécules tensioactives sur les mécanismes de transport et de rétention des tensioactifs dans les milieux poreux saturés en vue de leur dépollution. Une démarche de sélection progressive des produits a permis dans un premier temps une présélection des produits disponibles sur le marché (douze tensioactifs). Ceux-ci ont été analysés et caractérisés en laboratoire. Puis, des expériences de traçage et d’injection de solutions tensioactives ont été menées à l’échelle de colonnes de laboratoire dans deux milieux poreux aux propriétés distinctes et avec les trois tensioactifs ayant le meilleur potentiel pour l’application choisie. Ils ont été comparés au Triton X100, un tensioactif pétrosourcé, référence dans le domaine de la dépollution des sols.Afin de caractériser l’écoulement dans les milieux poreux, un soluté non-réactif a été utilisé comme traceur de l’eau. Des simulations numériques ont été réalisées en utilisant le code de calcul HYDRUS-1D afin de modéliser l’écoulement et d’estimer les paramètres de transport et de dépôt des tensioactifs. Ces résultats ont permis d’émettre des hypothèses sur les mécanismes d’interaction entre les tensioactifs, le polluant hydrophobe et le milieu poreux menant ainsi à une meilleure compréhension du procédé et à l’amélioration de son efficacité.Understanding transport and interactions of bio-based surfactants in porous medium is a main issue in environmental applications, in particular for the control of the soil washing remediation process. The objective of this work is to study the role of the physical heterogeneity and hydrodynamics of the medium as well as the impact of the properties of surfactant molecules on the mechanisms of transport and retention of surfactants in a saturated porous media,A progressive product selection process has allowed a preselection of the products available on the market (twelve surfactants). These were analyzed and characterized in the laboratory. Then, tracer experiments and injection of surfactant solutions were carried out at laboratory column scale with two porous media with distinct properties and using the three surfactants having the best potential for the soil washing application. They were compared to Triton XIOO, a petroleum-based surfactant, a reference in soil remediation field.In order to characterize the flow in porous media, a non-reactive solute was used as a water tracer. Numerical simulations were performed using the HYDRUS-ID code to model the flow and estimate the transport and deposition parameters of surfactants. These results made it possible to put forward hypotheses on the mechanisms of interaction between the surfactants, the hydrophobic pollutant and the porous medium, thus they lead to a better understanding o the process and to the improvement of its efficiency
Romance portrayed in Sophie Kinsella's finding Audrey Novel
Get PDFThis research aims to describe the relationship between Audrey and Linus relationship using John G. Cawelti formula theory. The study shows that author use pamela formula to describe the story plot
WHAT WE OWE TO CHILDREN: A RAWLSIAN PERSPECTIVE IN AN IRISH CONTEXT
No full textProvided by the author(s) and NUI Galway in accordance with publisher policies. Please cite the published version when available. Downloaded 2016-05-11T19:50:14Z Some rights reserved. For more information, please see the item record link above. Title What we owe to children: A rawlsian perspective in an irish context Author(s) Cahill, Audrey
Sharing a funder's perspective: using and supporting various approaches to communicate progress toward meeting ecological outcomes
No full textKen Fetcho, effectiveness monitoring coordinator & Audrey Hatch, conservation outcomes coordinatorTitle from PDF caption (viewed on December 27, 2022)This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposesMode of access: Internet from the Oregon Government Publications CollectionText in Englis
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