918 research outputs found

    Continuità e aderenza terapeutica nei giovani all’esordio psicotico: il modello di intervento integrato del Servizio Psichiatrico di Bolzano. [Continuity of care and therapeutic adherence in young people at psychosis onset: the integrated intervention model of the Psychiatric Service of Bolzano]

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    Scopo. Presentare: 1) il percorso di trasformazione del Servizio Psichiatrico di Bolzano verso un assetto organizzativo orientato a un’offerta tempestiva, intensiva, specifica e multimodale per gli utenti all’esordio psicotico e i loro familiari; 2) l’andamento clinico e sociale nel corso di 12 mesi della coorte dei pazienti avviati al progetto “Interventi Precoci”. Metodi. Studio naturalistico longitudinale che valuta l’andamento nel corso di 12 mesi di una coorte di pazienti al primo episodio psicotico, reclutata nell’area di competenza territoriale del Servizio Psichiatrico di Bolzano e avviata al progetto “Interventi Precoci”. Le caratteristiche socio-demografiche, abitative e lavorative, le erogazioni delle prestazioni (intervento medico, psicoterapia, psicoeducazione familiare, intervento sociale) e i ricoveri ospedalieri sono stati ricavati dalla cartella clinica informatizzata. Stato psicopatologico e funzionamento globale sono stati valutati, rispettivamente, con la Positive and Negative Syndrome Scale (PANSS) e la Global Assesment of Functioning (GAF). Risultati. Nei primi cinque anni di attività del progetto (2012-2017) sono stati trattati 116 pazienti. Al follow-up (FU) a 12 mesi, l’83,6% risulta in carico, il 7,7% si è trasferito in altra sede e l’8,5% ha abbandonato il percorso. Non risultano differenze di età e genere tra pazienti in carico e quelli che hanno interrotto il progetto. Tutti i pazienti hanno usufruito di un trattamento integrato specifico; il 16% ha inoltre usufruito di un trattamento intensivo in regime residenziale. I punteggi PANSS totale, positiva e negativa, hanno registrato una riduzione significativa dal baseline (BL) al FU; parallelamente si è assistito a un aumento significativo dei punteggi GAF. Solamente il 13,5% è andato incontro a un ricovero ospedaliero (Servizio Psichiatrico Diagnosi e Cura, SPDC) nel corso di 12 mesi. Al FU il tasso di disoccupazione si riduce del 27,1% e il numero dei pazienti con un’occupazione lavorativa raddoppia rispetto al BL. Discussione e conclusioni. Il progetto “Interventi Precoci” è risultato in grado di fornire trattamenti integrati, multiprofessionali e tempestivi fin dalle prime fasi del disturbo, secondo quanto raccomandato dalle linee guida internazionali, promuovendo un miglioramento significativo dei pazienti sia sul piano clinico che in termini di funzionamento sociale.Aim: To report on: 1) the modification process occurred within the Psychiatric Service of Bolzano toward an early, intensive, specific and multimodal system of care for patients experiencing their first psychotic episode and their family members; 2) the 12-month clinical and social course of a sample of patients referred to the "Early Intervention Project". Methods: Longitudinal naturalist study evaluating the 12-month clinical and outcome of a cohort of first-episode psychosis patients consecutively referred to the "Early Intervention Project" implemented within the Psychiatric Service of Bolzano. Socio-demographic characteristics, housing situation and occupational status, interventions offered (medical intervention, psychotherapy, psychoeducation to family members, social intervention) and hospital admissions were drawn from electronic medical records. Levels of psychopathology and global functioning were assessed using the Positive and Negative Syndrome Scale (PANSS) and the Global assessment of Functioning (GAF), respectively. Results: During the first five years of activity (2012-2017) 116 patients had been referred to the Project. At 12 months 83.6%were still in charge, 7.76% moved to another area, 8.5% have abandoned the intervention. No significant difference in terms of age and gender was found between patients who remained in the project and those who lost contact. All patients had received specific integrated treatment; moreover, 16% had received intensive residential care. Notably, only 13.5% have had a hospital readmission over the 12 months of intervention. The PANSS total, positive and negative scores displayed significant reduction from baseline (BL) to follow-up (FU); in parallel, increase in GAF score from BL to FU was observed. All patients employed at BL were able to keep their job at FU; 17% of all patients unemployed at baseline were employed at FU. Discussion and conclusion: The "Early Intervention Project" implemented in Bolzano was found to ensure integrated, multidisciplinary and early treatment, as defined by the most recent international guidelines, which produced significant improvement in both clinical and social outcomes in a cohort of first-episode psychosis patients

    Exposure-Tolerant Imaging Solution forCultural Heritage Monitoring

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    This paper describes a simple and cheap solution specifically designed for monitoring the degradation of thin coatings employed for metal protection. The proposed solution employs a commercial photocamera and a frequency-domain-based approach that is capable of highlighting the surface uniformity changes due to initial corrosion. Even though the proposed solution is specifically designed to monitor the long-time performance of protective coatings employed for the restoration of silver artifacts, it can be successfully used also for assessing the conservation state of other ancient metallic works of art. The proposed solution is made tolerant to exposure changes by using a procedure for sensor nonlinearity identification and correction, does not require a precise lighting control, and employs only free open-source software, so that its overall cost is very low and can be used also by not specifically trained operator

    The C-Section Epidemic: What's Tort Reform Got to Do With It?

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    Today one in three babies in the United States comes into the world by cesarean section. The cesarean section has become the most commonly performed operating room procedure in the United States. Conventional wisdom holds that malpractice liability bears primary responsibility for the cesarean section epidemic and that tort reform, which caps physician liability, holds the key to its reduction. This article presents new aggregate empirical data that debunks this view. For the first time, it provides a national cesarean rate for births subject to damage caps and a national cesarean rate for births without damage caps. This data shows that a woman is not less likely to give birth by cesarean section in a state with damage caps than in one without. Thus, either damage caps are insufficient to address physicians’ concerns or other explanations better account for the overuse of the procedure. The empirical analysis will assist policy makers and advocates seeking to reduce the cesarean rate as well as contribute to consideration of the efficacy of medical malpractice reform as a means to reduce the broader problem of medical overtreatment. The article then outlines three policy initiatives to reduce the cesarean section rate. First, it suggests upending the current payment practice for deliveries. Contrary to the present norm, it proposes that obstetricians receive more rather than less to deliver vaginally to compensate them for the extra time that vaginal delivery takes compared to cesarean delivery. Second, rather than looking to tort reform to reduce cesarean section rates, the article explores whether malpractice insurance providers themselves are contributing to the cesarean section epidemic and advocates two novel medical malpractice insurance reforms to address this problem. Third, it advocates public disclosure of hospital and physician cesarean section rates so that women can make informed decisions when selecting their health care providers and when determining whether to have a cesarean section

    Bridging the Distance: Exploring Informal Communication and its Impact on Productivity, Well-Being, and Workplace Dynamics in Hybrid Work Environments

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    Author Sabrina Schopf, BScMasterarbeit Johannes Kepler Universität Linz 202

    The management of multiple aspiration : a case study of a merger in an Austrian hospital

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    Author Sabrina Hermanseder, BAAbstract in englischer SpracheMasterarbeit Universität Linz 201

    Feminisme Dalam Novel Asya Story Karya Sabrina Febrianti

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    The novel Asya Story by Sabrina Febrianti contains the life story of a woman named Asya. In this novel also discusses how Asya's obstinacy and strength in overcoming every problem in his face. The problems described in this study are (1) Are feminism questions about aspects of the wisdom of the female characters in the novel "Asya Story" by Sabrina Febrianti?, (2), (3) Women's questions in the "Asya Story" novel by Sabrina Febrianti? The purpose of this study is to analyze data about the aspects of feminism psychology that discusses the character of female characters, the pressure of feelings of female characters, and the taste of female characters. The theory used by the author to analyze this research is the theory of Sikana (2005), Lubis (2016). The agreement used is a qualitative agreement. The type of research used is library research. The method used is descriptive method. The technique used is the hermeneutic technique. Data analysis using content analysis techniques. The results of the research submitted about the facts of feminism, especially about the policy aspects that often appear in the novel Asya Story by Sabrina Febrianti is a challenge of the character (character) women and recovery figures, women women Figure in the same story with humans in everyday life who always have different thoughts. Human life is often tested with tests and trials, as is the character who discusses the author in a novel. Exams and experiments that will shape the pressure and stress in humans

    Handheld-Impedance-Measurement System with seven-decade capability and potentiostatic function

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    This paper describes design and test of a new impedance-measurement system for nonlinear devices that exhibits a seven-decade range and works down to a frequency of 0.01 Hz. The system is specifically designed for electrochemical measurements, but the proposed architecture can be employed in many other fields where flexible signal generation and analysis are required. The system employs an unconventional signal generator based on two pulsewidth modulation (PWM) oscillators and an autocalibration system that allows uncertainties of less than 3% to be obtained over a range of 1 kΩ to 100 GΩ. A synchronous demodulation processing allows the noise superimposed to the low-amplitude input signals to be made negligibl

    Solving Problems through Katasterismos: Classical Reception in New Zealand author Sabrina Malcolm’s Zeustian Logic

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    New Zealand writer Sabrina Malcolm’s 2017 novel Zeustian Logic is a contemporary school story about a family struggling to deal with grief. This text follows in a decades-long tradition of New Zealand YA literature employing Classical reception. The novel illustrates how Classical myth helps a contemporary New Zealand teenager (Tuttle) come to terms with his father’s death and his own feelings of helplessness, frustration and anger. This chapter examines the role of Classical reception in this novel, discussing how the author uses star mythology to underpin the depiction of the protagonist’s coming-of-age. More than that, Malcolm compares Tuttle’s feelings with ancient perceptions of anger and grief and skillfully casts Tuttle, in his quest for knowledge, as a modern-day Telemachus. The chapter concludes with a look at how Tuttle’s attitudes towards Zeus change, as he matures

    COX16 is required for assembly of cytochrome c oxidase in human cells and is involved in copper delivery to COX2

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    Cytochrome c oxidase (COX), complex IV of the mitochondrial respiratory chain, is comprised of 14 structural subunits, several prosthetic groups and metal cofactors, among which copper. Its biosynthesis involves a number of ancillary proteins, encoded by the COX-assembly genes that are required for the stabilization and membrane insertion of the nascent polypeptides, the synthesis of the prosthetic groups, and the delivery of the metal cofactors, in particular of copper. Recently, a modular model for COX assembly has been proposed, based on the sequential incorporation of different assembly modules formed by specific subunits. We have cloned and characterized the human homologue of yeast COX16. We show that human COX16 encodes a small mitochondrial transmembrane protein that faces the intermembrane space and is highly expressed in skeletal and cardiac muscle. Its knockdown in C. elegans produces COX deficiency, and its ablation in HEK293 cells impairs COX assembly. Interestingly, COX16 knockout cells retain significant COX activity, suggesting that the function of COX16 is partially redundant. Analysis of steady-state levels of COX subunits and of assembly intermediates by Blue-Native gels shows a pattern similar to that reported in cells lacking COX18, suggesting that COX16 is required for the formation of the COX2 subassembly module. Moreover, COX16 co-immunoprecipitates with COX2. Finally, we found that copper supplementation increases COX activity and restores normal steady state levels of COX subunits in COX16 knockout cells, indicating that, even in the absence of a canonical copper binding motif, COX16 could be involved in copper delivery to COX2
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