131,700 research outputs found

    D. Seb. Ioann. Lud. Doering Commentatio Medica De Vomitu

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    D. SEB. IOANN. LUD. DOERING COMMENTATIO MEDICA DE VOMITU D. Seb. Ioann. Lud. Doering Commentatio Medica De Vomitu ([1]) Binding ( - ) Title page ([1]) Dedication ([3]) Praefatio. ([5]) Sectio I. Quaedam de Vomitu in genere. ([7]) Sectio II. De Signis Vomitus diagnosticis. (13) Sectio III. De Prognosi Vomitus. (17) Epilogus. (28) Theses. (31) Binding ( - ) Section ( -

    Cadernos Escolares, Doering, 3ª série do curso ginasial, 1963, RS

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    Os cadernos escolares são de encadernação tipo canoa. Estão preenchidos com caneta tinteiro e lápis coloridos. Item digitalizado por Nícolas Giovani da Rosa.Estes quatros cadernos escolares, de 1963, pertenceram a Claus Doering e foram usados na 3ª série do Curso Ginasial do Colégio Evangélico Augusto Pestana, RS. a) Caderno de Geometria; b) Caderno de Matemática; c) Caderno de Desenho Livre; d) Caderno de Exercícios de Geometria

    Intermittency and regularity issues in 3D Navier-Stokes turbulence

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    Two related open problems in the theory of 3 D Navier-Stokes turbulence are discussed in this paper. The first is the phenomenon of intermittency in the dissipation field. Dissipation-range intermittency was first discovered experimentally by Batchelor and Townsend over fifty years ago. It is characterized by spatio-temporal binary behaviour in which long, quiescent periods in the velocity signal are interrupted by short, active ‘events’ during which there are violent fluctuations away from the average. The second and related problem is whether solutions of the 3 D Navier-Stokes equations develop finite time singularities during these events. This paper shows that Leray’s weak solutions of the three-dimensional incompressible Navier-Stokes equations can have a binary character in time. The time-axis is split into ‘good’ and ‘bad’ intervals: on the ‘good’ intervals solutions are bounded and regular, whereas singularities are still possible within the ‘bad’ intervals. An estimate for the width of the latter is very small and decreases with increasing Reynolds number. It also decreases relative to the lengths of the good intervals as the Reynolds number increases. Within these ‘bad’ intervals, lower bounds on the local energy dissipation rate and other quantities, such as || u (·, t )|| ∞ and ||∇ u (·, t )|| ∞ , are very large, resulting in strong dynamics at sub-Kolmogorov scales. Intersections of bad intervals for n ≧1 are related to the potentially singular set in time. It is also proved that the Navier-Stokes equations are conditionally regular provided, in a given ‘bad’ interval, the energy has a lower bound that is decaying exponentially in time.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46170/1/205_2005_Article_382.pd

    Data from: Distribution of label spacings for genome mapping in nanochannels

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    Ödman, Daniel; Werner, Erik; Dorfman, Kevin D; Doering, Charles M; Mehlig, Bernhard. (2018). Data from: Distribution of label spacings for genome mapping in nanochannels. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/198066

    Macrophage response to Mycobacterium tuberculosis infection

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    The immune response to Mycobacteriumtuberculosis (Mtb) infection is the formation of multicellular lesions, or granolomas, in the lung of the individual. However, the structure of the granulomas and the spatial distribution of the immune cells within is not well understood. In this paper we develop a mathematical model investigating the early and initial immune response to Mtb. The model consists of coupled reaction-diffusion-advection partial differential equations governing the dynamics of the relevant macrophage and bacteria populations and a bacteria-produced chemokine. Our novel application of mathematical concepts of internal states and internal velocity allows us to begin to study this unique immunological structure. Volume changes resulting from proliferation and death terms generate a velocity field by which all cells are transported within the forming granuloma. We present numerical results for two distinct infection outcomes: controlled and uncontrolled granuloma growth. Using a simplified model we are able to analytically determine conditions under which the bacteria population decreases, representing early clearance of infection, or grows, representing the initial stages of granuloma formation.</p

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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