1,720,954 research outputs found
PERBEDAAN KADAR GLUKOSA, NATRIUM, KALIUM, DAN KLORIDA SERUM BERDASARKAN DURASI DAN RELATIVE CENTRIFUGAL FORCE SENTRIFUGASI
Full text linkLatar Belakang: Sentrifugasi untuk persiapan sampel berpengaruh terhadap luaran pemeriksaan laboratorium. Turnaround time (TAT) memanjang dapat menyebabkan ketidakpuasan terhadap layanan laboratorium dan memengaruhi tatalaksana terutama pemeriksaan laboratorium yang membutuhkan hasil segera seperti glukosa dan elektrolit (natrium, kalium, dan klorida). Pengurangan durasi sentrifugasi diperlukan untuk memperpendek TAT tanpa mengubah kualitas hasil analisis. Penelitian ini bertujuan untuk mengetahui perbedaan kadar glukosa, natrium, kalium, dan klorida antara spesimen yang disentrifugasi selama 5 menit dengan relative centrifugal force (RCF) 3000xg dan 15 menit 1500xg.
Metode: Penelitian analitik dengan rancangan potong lintang dilakukan pada 64 subjek dewasa yang memenuhi kriteria inklusi dan eksklusi. Darah vena dimasukkan ke BD vacutainer SST II Advance Tubes dan dipisahkan komponennya menggunakan
sentrifus. Jenis parameter yang diperiksa meliputi glukosa, natrium, kalium, dan klorida. Sentrifugasi spesimen dilakukan dengan 2 metode. Tabung pertama disentrifugasi selama 5 menit dengan RCF 3000xg, tabung kedua disentrifugasi selama 15 menit dengan RCF 1500xg. Glukosa, natrium, kalium, dan klorida diperiksa dengan alat kimia klinik otomatis. Data univariat disajikan dalam bentuk
rerata dan median, data bivariat dianalisis menggunakan paired t test dan Wilcoxon, bermakna jika nilai p<0,05.
Hasil: Rerata usia subjek penelitian 19,71 (1,15) tahun, sebanyak 66,1% adalah perempuan. Kadar parameter laboratorium yang disentrifugasi selama 5 menit 3000xg dan 15 menit 1500xg adalah: glukosa (mg/dL) 90,90 (9,88) dan 90,77 (9,61) p=0,180; natrium (mmol/L) 138,67 (4,74) dan 138,38 (4,52) p=0,075; kalium (mmol/L) 4,32 (0,32) dan 4,31 (0,33) p=0,089; klorida (mmol/L) 100,58 (4,32) dan 100,33 (4,17) p=0,140.
Simpulan: Kadar glukosa, natrium, kalium, dan klorida serum pada spesimen yang disentrifugasi 5 menit 3000xg dengan 15 menit 1500xg tidak berbeda.
Saran: Turnaround time pemeriksaan glukosa, natrium, kalium, dan klorida dapat diperpendek tanpa memengaruhi hasil pemeriksaan pada sentrifugasi 5 menit 3000x
Profound Immunosuppression with Reversed CD4:CD8 Ratio in a Tuberculosis Patient with Acquired Immunodeficiency Syndrome: A Case Report
Full text linkBackground: The co-occurrence of tuberculosis (TB) and acquired immunodeficiency syndrome (AIDS) presents a formidable clinical challenge due to the synergistic impact on the immune system. This case report describes a patient with TB/AIDS co-infection exhibiting profound immunosuppression characterized by a severely diminished CD4 count and an unusual reversal of the CD4:CD8 ratio.
Case presentation: A 39-year-old male presented with symptoms indicative of both TB and advanced HIV infection, including shortness of breath, weight loss, and oral thrush. Physical examination revealed bilateral lung crackles. Laboratory investigations confirmed pulmonary TB and revealed a critically low CD4 count (6 cells/µL), and a CD8 count of 71 cells/µL, resulting in a reversed CD4:CD8 ratio of 0.08. The patient's HIV viral load was markedly elevated at 598,403 copies/mL. This case underscores the complex interplay between TB and HIV, highlighting the profound impact of co-infection on immune system function. The patient's severely depleted CD4 count and the atypical CD4:CD8 ratio reflect the advanced stage of HIV infection and the superimposed TB. The findings emphasize the need for close monitoring and aggressive management of co-infected patients to mitigate the risk of opportunistic infections and disease progression.
Conclusion: This case report documents a rare and severe presentation of TB/AIDS co-infection with profound immunosuppression and a reversed CD4:CD8 ratio. It serves as a reminder of the significant morbidity and mortality associated with advanced HIV and TB co-infection, particularly in cases of delayed diagnosis or suboptimal treatment adherence
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
- …
