39 research outputs found

    Les trois âges de la ville algérienne

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    The author expresses points for discussion on the analysis of the existing types of fabric, concerning three urban models set up during the development of the city of Algiers : the traditional city, now damaged, the interrupted colonial city and the unfinished metropolis cohabit and make the modem Algerian capital an extremely hybrid urbanistic and architectural reality.L’auteur formule des éléments de réflexion sur l’analyse des types de tissus existants, relevant de trois modèles urbains mis en place au cours du développement de la ville d Alger : la ville traditionnelle désormais dégradée, la ville coloniale interrompue, et la métropole inachevée, se juxtaposent et font de la capitale algérienne aujourd’hui, une réalité urbanistique et architecturale très hybride.Boudiaf Bouzid. Les trois âges de la ville algérienne. In: Villes en parallèle, n°36-37, décembre 2003. Villes algériennes. pp. 28-47

    Powers of Powerlessness: The Politics of Defeat in the Cinema of Nouri Bouzid

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    This article examines the cultural politics of defeat in the cinema of Tunisian filmmaker Nouri Bouzid. Taking a lead from Bouzid’s directorial début Man of Ashes, the author focuses on Golden Horseshoes (1989) and Making of (2006), the two films that best dramatize the continuities between the crisis of filiation and the crisis of affiliation, and that deal head-on with left-wing (socialism) and right-wing (religious fundamentalism) ideologies. These two early films paint the broad strokes of Bouzid’s cinematic project, specifically its entwined dramatization of the crisis of filiation ( Man of Ashes) and the crisis of affiliation ( Golden Horseshoes), the profound loss of any discernible project of psychoaffective investiture, intellectual commitment and decolonial resistance, especially in the wake of the spectacular dissolution of international socialism and the ensuing triumphalism of global capitalism and financial imperialism. </jats:p

    Formulation and Optimization of Diclofenac Sodium Loaded Ethylcellulose Nanoparticles

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    Design of experiment (DoE) is a useful time and cost-effective tool for analyzing the effect of independent variables on the formulation characteristics. The aim of this study is to evaluate the effect of the process variables on the characteristics involved in the preparation of Diclofenac Sodium (DC) loaded ethylcellulose (EC) nanoparticles (NP) using Central Composite Design (CCD). NP were prepared by W/O/W emulsion solvent evaporation method. Three factors were investigated (DC/EC mass ratio, PVA concentration, homogenization speed) in order to optimize the entrapment efficiency (EE) and the particle size of NP. The optimal formulation was characterized by Fourier Transform Infrared (FTIR), Scanning Electron Microscopy (SEM), Differential Scanning Calorimetry (DSC), and&nbsp;in vitro&nbsp;release. Optimized formulation showed an EE of 49.09 % and an average particle size of 226.83 nm with a polydispersity index of 0.271. No drug-polymer interaction was observed in FTIR and DSC analysis. SEM images showed that the particles are spherical and uniform. The in vitro release study showed a sustained release nature, 53.98 % of the encapsulated drug has been released over 24hours period. This study demonstrated that statistical experimental design methodology can optimize the formulation and the process variables to achieve favorable responses

    Formulation and Characterization of Poly (Acrylic Acid)- Co-Chitosan Nanoparticles as pH-Thermo-Responsive System to Control Delivery

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    International audienceThe present study aims to develop a pH thermosensitive nanocarriers as a drug delivery system to better controll drug release. Nanoparticles was developed by the combination of smart polymers, chitosan and poly(acrylic acid) were chosen as biodegradable vectors to encapsulate and transport the drug. The used method was based on the polymerization of acrylic acid using reticulated chitosan as a template. Analysis of particle size, Zeta potential, and size distribution revealed that most of the resulting nanoparticles had an average diameter less than 100nm, with a high Zeta potentiel about -29.7 mV and a narrow size distribution. In addition, the developed system showed an encapsulation efficiency around 97%. In vitro release test was achieved using different buffer solutions with pH equal to 1.2, 3.6, 4.2, 4.8, 6.8 and 7.4. The release profiles showed that nanoparticles provide drug protection at different pH values. They responded at pH = 3.6 and provided sustained controlled release of up to 62.62% over 8 hours. The results reveal that the prepared nanoparticles can be used as drug delivery carriers. They can improve therapeutic efficiency of the drugs used in the treatment of inflamed tissues where the pH is around 3.6 as in the Crohn disease

    Formulation and Characterization of Poly (Acrylic Acid)- Co-Chitosan Nanoparticles as pH-Thermo-Responsive System to Control Delivery

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    The present study aims to develop a pH thermosensitive nanocarriers as a drug delivery system to better controll drug release. Nanoparticles was developed by the combination of smart polymers, chitosan and poly(acrylic acid) were chosen as biodegradable vectors to encapsulate and transport the drug. The used method was based on the polymerization of acrylic acid using reticulated chitosan as a template. Analysis of particle size, Zeta potential, and size distribution revealed that most of the resulting nanoparticles had an average diameter less than 100nm, with a high Zeta potentiel about -29.7 mV and a narrow size distribution. In addition, the developed system showed an encapsulation efficiency around 97%. In vitro release test was achieved using different buffer solutions with pH equal to 1.2, 3.6, 4.2, 4.8, 6.8 and 7.4. The release profiles showed that nanoparticles provide drug protection at different pH values. They responded at pH = 3.6 and provided sustained controlled release of up to 62.62% over 8 hours. The results reveal that the prepared nanoparticles can be used as drug delivery carriers. They can improve therapeutic efficiency of the drugs used in the treatment of inflamed tissues where the pH is around 3.6 as in the Crohn disease
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