314 research outputs found
Pope Paul VI and St. Benedict
No full textDvadesetak godina nakon završetka Drugoga svjetskog rata papa Pavao VI. proglasio je sv. Benedikta zaštitnikom Europe. Neposredan povod bila je obnova benediktinske kuće-matice, samostana na Monte Cassinu, koji je posve razrušen u ratnim razaranjima Drugoga svjetskog rata. Nakon uvodnih misli, u kojima ukazuje na neposredni kontekst apostolskog pisma Pacis nuntius, kojim je papa Pavao VI. sv. Benedikta proglasio zaštitnikom Europe, autor sažeto prikazuje sadržaj Pisma. U trećem dijelu članka autor progovara o širem povijesnom kontekstu u kojem je nastalo apostolsko pismo Pacis nuntius, odnosno o procesima dezintegracije koji su doveli do Drugoga svjetskog rata. U posljednjem dijelu članka autor progovara o mogućoj aktualnosti apostolskog pisma Pacis nuntius, odnosno zaključuje kako nikakvo ekonomsko povezivanje nije i ne će biti dostatno za europsku zajednicu naroda. Istinsko zajedništvo moguće je jedino na kršćanskim temeljima, jer je kršćanstvo kroza stoljeća nadahnjivalo i izgrađivalo Europu i oblikovalo povijest svih europskih naroda.Some twenty years after the end of World War II, Pope Paul VI declared St. Benedict as the patron saint of Europe. The immediate reason was the restoration of the Benedictine motherhouse, the monastery on Monte Cassino, which was completely destroyed in the war devastation of the Second World War. After the introductory thoughts, in which the author points to the immediate context of the apostolic letter Pacis Nuntius, by which Pope Paul VI proclaimed St. Benedict the patron of Europe, the author summarizes the content of the Letter. In the third part of the article, the author talks about the wider historical context in which the apostolic letter Pacis Nuntius was created, that is, about the processes of disintegration that led to the Second World War. In the last part of the article, the author talks about the possible current issues of the apostolic letter Pacis Nuntius, that is, he concludes that no economic bonds are and will not be adequate and sufficient for the European community of peoples. True unity is possible only on Christian foundations, because Christianity has inspired and built Europe throughout the centuries and shaped the history of all European nations
Paul, Antioch, and Jerusalem: a study in relationships and authority in earliest Christianity
No full textPaul's life and work, including his relationship with the Jerusalem church, were dynamic, rather than having been predetermined in his conversion. The Antiochene church was crucial to Paul's development, to a degree not previously appreciated. Little is known of the years following Paul's conversion, other than it was unsettled, and included travels and sojourns in Arabia, Damascus, Jerusalem, and Tarsus. The encounter with the Jerusalem church did not result in a stable relationship or social integration. It was at Antioch that Paul was first fully incorporated into a Christian community, from which he derived his dyadic identity, and later his apostolic commission. His relationship with the Jerusalem church consisted in corporate participation in the коιυυυία between the churches of Jerusalem and Antioch. In this context, Paul joined Barnabas in defending the Antiochene gospel of uncircumcision, and not his own theology or apostleship, at the Jerusalem conference. The Antioch incident resulted in Paul's separation from the Antiochene church, and exclusion from its коιυυυία with the Jerusalem church. His independent ministry followed, during which he developed his conception of apostleship independent of human authority, in which his self-identity is bound up with the gospel, in response to his isolation, and loss of dyadic identity and apostolic commission. Paul sought to end his isolation through reconciliation with the Antiochene church, and, through its коιυυυία, with the Jerusalem church. This was the object of the collection, but the crisis in Corinth delayed completion, requiring Paul to convey his offering separately. His implicit claim to коιυυυία accordingly became overt, and the collection became the basis, rather than a correlative obligation, of the relationship. This jeopardized the acceptability of Paul's overtures, and, while his reception is uncertain, the journey occasioned his arrest, and ended his missionary career
Messages of John Paul II for Croatian Pastoral Renewal
No full textSveti papa Ivan Pavao II. posjetio je Hrvatsku 1994., 1998. i 2003. godine, uputivši ohrabrujuće i sadržajne poruke hrvatskoj Crkvi kako bi učvrstio braću i sestre katoličke zajednice koji su u doba vjerskih progona ostali vjerni Kristu. Pastoralne poruke otkrivaju koliko je Papa razumio i volio Hrvate, želeći da Crkva doživi obnovu naviještajući evanđelje i svjedočeći vjeru. Člankopisac prosuđuje društveno-kulturno i crkveno surječje njegovih dolazaka i poslanih poruka. U raščlambi porukâ osvrće se na komunističko doba, na događaje Domovinskoga rata i na prijelazno razdoblje u demokratski sustav. U drugomu dijelu prikazuje područja za pastoralnu obnovu, raščlanjujući smjernice poslane Crkvi i svim hrvatskim građanima.Saint Pope John Paul II visited Croatia in 1994, 1998 and 2003, sending encouraging and meaningful messages to the Croatian Church in order to strengthen the brothers and sisters of the Catholic community, who remained faithful to Christ during the times of religious persecution. The pastoral messages reveal how much the Pope understood and loved the Croats, wishing the Church to experience renewal by proclaiming the Gospel and bearing witness to the faith. The author considers the socio-cultural and church context of his visits and the messages he sent. In his analysis of the messages, the author looks back at the communist era, the events of the Croatian War of Independence, and the period of transition to a democratic system. In the second part, he presents areas for pastoral renewal, analysing the guidelines sent to the Church and all Croatian citizens
Thermodynamic modelling assessment of the ternary system Cs-Mo-O
No full textThis work reports the thermodynamic modelling assessment of the rather complex Cs-Mo-O system, which is key for the understanding of fission products chemistry in oxide fuelled Light Water Reactors (LWRs) and next generation Sodium-cooled and Lead-cooled Fast Reactors (SFRs and LFRs). The model accounts for the existence of the ternary molybdates Cs2MoO4 (α and β), Cs2Mo2O7 (α and β), Cs2Mo3O10, Cs2Mo4O13, Cs2Mo5O16, and Cs2Mo7O22, for which sufficient structural and thermodynamic information are available in the literature. These phases are treated as stoichiometric in the model. The liquid phase is described with an ionic two-sublattice model, and the gas phase as an ideal mixture. The optimized Gibbs energies are assessed with respect to the known thermodynamic and phase equilibrium data in the Cs2MoO4-MoO3 pseudo-binary section. A good agreement is generally obtained within experimental uncertainties. The calculated vapour pressures above Cs2MoO4 (solid and liquid) are also compared to the available experimental data. Finally, isotherms of the Cs-Mo-O ternary phase diagram are calculated at relevant temperatures for the assessment of the fuel pin behaviour in LWRs, SFRs and LFRs.RST/Reactor Physics and Nuclear MaterialsCommunication Education & Student Affair
Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections.
No full textBACKGROUND: Plasmodium knowlesi is a cause of symptomatic and potentially fatal infections in humans. There are no studies assessing the detailed parasitological response to treatment of knowlesi malaria infections in man and whether antimalarial resistance occurs.
METHODS: A prospective observational study of oral chloroquine and primaquine therapy was conducted in consecutive patients admitted to Kapit Hospital, Sarawak, Malaysian Borneo with PCR-confirmed single P. knowlesi infections. These patients were given oral chloroquine for three days, and at 24 hours oral primaquine was administered for two consecutive days, primarily as a gametocidal agent. Clinical and parasitological responses were recorded at 6-hourly intervals during the first 24 hours, daily until discharge and then weekly to day 28. Vivax malaria patients were studied as a comparator group.
RESULTS: Of 96 knowlesi malaria patients who met the study criteria, 73 were recruited to an assessment of the acute response to treatment and 60 completed follow-up over 28 days. On admission, the mean parasite stage distributions were 49.5%, 41.5%, 4.0% and 5.6% for early trophozoites, late trophozoites, schizonts and gametocytes respectively. The median fever clearance time was 26.5 [inter-quartile range 16-34] hours. The mean times to 50% (PCT50) and 90% (PCT90) parasite clearance were 3.1 (95% confidence intervals [CI] 2.8-3.4) hours and 10.3 (9.4-11.4) hours. These were more rapid than in a group of 23 patients with vivax malaria 6.3 (5.3-7.8) hours and 20.9 (17.6-25.9) hours; P = 0.02). It was difficult to assess the effect of primaquine on P. knowlesi parasites, due to the rapid anti-malarial properties of chloroquine and since primaquine was administered 24 hours after chloroquine. No P. knowlesi recrudescences or re-infections were detected by PCR.
CONCLUSIONS: Chloroquine plus primaqine is an inexpensive and highly effective treatment for uncomplicated knowlesi malaria infections in humans and there is no evidence of drug resistance. Further studies using alternative anti-malarial drugs, including artemisinin derivatives, would be desirable to define optimal management strategies for P. knowlesi
Paul De Kruif: The Microbe Hunter and Author
No full textLaupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library hopes that the speakers and topics selected will promote a greater understanding of the historical and philosophical underpinnings of today's health care disciplines.Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studie
Biblical passages in the homilies and speeches of John Paul II to clerics during his pastoral visit to Sarajevo
No full textU uvodnom dijelu rada autor tematizira društveni kontekst prvoga pastoralnog pohoda Svetoga Oca Ivana Pavla II. Sarajevu i Bosni i Hercegovini iz travnja 1997. godine, koji je u bitnoj povezanosti s namjeravanim i neostvarenim pohodom iz ratne 1994. godine. Budući da su ova dva Papina pastoralna pohoda međusobno povezana i međuovisna, autor u nastavku kroz prizmu biblijskih mjesta analizira izabrane govore Svetoga Oca iz neostvarenog i ostvarenog Papinog posjeta: dvije homilije i dva govora klericima koje je Sveti Otac izrekao, odnosno planirao izreći, na hrvatskome jeziku. U radu se stavlja osobit naglasak na tzv. indirektne citate, odnosno ona biblijska mjesta koja se izričito ne navode, ali se na njih aludira, tj. koja stoje u pozadini Papinih po(r)uka. U Zaključku su sabrani rezultati autorove analize Papinih homilija i govora iz navedenih pastoralnih pohoda te je iznesen vrijednosni sud s obzirom na biblijsku podlogu analiziranih Papinih riječi.In the introductory part of the paper, the author discusses the social context of the Holy Father John Paul II’s first pastoral visit to Sarajevo and Bosnia and Herzegovina in April 1997, which is significantly connected to the intended and unrealized visit in the war year of 1994. Since these two pastoral visits of the Pope are interconnected and interdependent, hence the author, through the prism of biblical passages, analyses selected speeches of the Holy Father from the unrealized and realized visits of the Pope: two homilies and two speeches to clerics that the Holy Father delivered, or planned to deliver, in the Croatian language. The paper places particular emphasis on the so-called indirect quotations, i.e. those biblical passages that are not explicitly cited but are alluded to, i.e. which stand in the background of the Pope's messages/lessons. The Conclusion summarizes the results of the author's analysis of the Pope's homilies and speeches from the aforementioned pastoral visits, and presents a value judgment with regard to the biblical basis of the analysed Pope's words
Swedish traveller with <it>Plasmodium knowlesi </it>malaria after visiting Malaysian Borneo
No full textAbstract Plasmodium knowlesi is typically found in nature in macaques and has recently been recognized as the fifth species of Plasmodium causing malaria in human populations in south-east Asia. A case of knowlesi malaria is described in a Swedish man, who became ill after returning from a short visit to Malaysian Borneo in October 2006. His P. knowlesi infection was not detected using a rapid diagnostic test for malaria, but was confirmed by PCR and molecular characterization. He responded rapidly to treatment with mefloquine. Evaluation of rapid diagnostic kits with further samples from knowlesi malaria patients are necessary, since early identification and appropriate anti-malarial treatment of suspected cases are essential due to the rapid growth and potentially life-threatening nature of P. knowlesi. Physicians should be aware that knowlesi infection is an important differential diagnosis in febrile travellers, with a recent travel history to forested areas in south-east Asia, including short-term travellers who tested negative with rapid diagnostic tests.</p
Molecular epidemiology and population genomics of Plasmodium knowlesi.
No full textMolecular epidemiology has been central to uncovering P. knowlesi as an important cause of human malaria in Southeast Asia, and to understanding the complex nature of this zoonosis. Species-specific parasite detection and characterization of sequences were vital to show that P. knowlesi was distinct from the human parasite species that had been presumed to cause all malaria. With established sensitive and specific molecular detection tools, surveys subsequently indicated the distribution of P. knowlesi infections in humans, wild primate reservoir host species, and mosquito vector species. The importance of studying P. knowlesi genetic polymorphism was indicated initially by analysing a few nuclear gene loci as well as the mitochondrial genome, and subsequently by multi-locus microsatellite analyses and whole-genome sequencing. Different human infections generally have unrelated P. knowlesi genotypes, acquired from the diverse local parasite reservoirs in macaques. However, individual human infections are usually less genetically complex than those of wild macaques which experience more frequent superinfection with different P. knowlesi genotypes. Multi-locus analyses have revealed deep population subdivisions within P. knowlesi, which are structured both geographically and in relation to different macaque reservoir host species. Simplified genotypic discrimination assays now enable efficient large-scale surveillance of the sympatric P. knowlesi subpopulations within Malaysian Borneo. The whole-genome sequence analyses have also identified loci under recent positive natural selection in the P. knowlesi genome, with evidence that different loci are affected in different populations. These provide a foundation to understand recent adaptation of the zoonotic parasite populations, and to track and interpret future changes as they emerge
Optimal design of experiments with simulation models of nearly saturated queues
No full textexperimental design;simulation models;queueing network;regression analysis
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