110,708 research outputs found

    Supplementary materials for ``Bayesian causal inference: a critical review''

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    Some background materials and R code for the paper: Li, F., Ding, P. and Mealli, F. (2023). Bayesian causal inference: a critical review. Philosophical Transactions of the Royal Society A, 381, 20220153

    The relationship of the ADP-ribosylating enzyme from S. solfataricus with DING proteins and its intracellular localization

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    The PARPSso thermoprotein from Sulfolobus solfataricus has been identified as a PARP-like enzyme that cleaves -NAD+ to synthesize oligomers of ADP-ribose and cross-reacts with polyclonal anti-PARP-1 catalytic site antibodies. Despite the biochemical properties that allow to correlate it to PARP enzymes, the N-terminal and partial amino acid sequence suggest the sulfolobal enzyme belongs to a different class of enzymes, the DING proteins. Considering the high sequence identity with the human DING protein HPBP and the lack of a nucleotide coding sequence in both human and sulfolobal genomes, we hypothesized that PARPSso might share other features with the human DING. Further analysis of PARPSso amino acid sequence addressed the research towards studying other possible similarities between human and sulfolobal protein and then to explain how PARPSso correlates with canonic PARPs. For the latter question, the peculiar behaviour of the thermozyme, that is biochemically, but not structurally related to the classic PARPs, stimulated to investigate by computational analysis and databank, whether the protein might be phylogenetically related to any already known PARP amino acid sequence. Moreover, immunochemical and enzymatic crossed analyses were performed to establish whether purified HPBP and PARPSso have common immunoreactive and functional behaviour. The second part of the research was focused on the localization of PARPSso within the sulfolobal cell. Our interest to this item arose from the property of some DING proteins to be membrane bound, suggested to work as membrane transporters. On the other hand, from previous studies, it is known that PARPSso is only partially solubilized from the starting cell homogenate provided by ICMIB (CNR), and the soluble enzyme is strictly associated with DNA. In this thesis work, whole cells collected by centrifugation from culture medium were subjected to a different extraction procedure. This procedure included also experimental conditions used to differentiate between soluble (i.e. cytoplasmic) and insoluble (i.e. membrane-bound) protein fractions. PARPSso and DNA distributions were determined by enzyme assay, immunoblotting and agarose gel electrophoresis. Reciprocal interactions of thermozyme, nucleic acid and membrane lipids were investigated with different techniques and methodologies (nucleoid preparation, fluorescence binding assays, fluorescence microscopy analysis)

    Ding, P. F.

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    Single-scattering properties of ice particles in the microwave regime: Temperature effect on the ice refractive index with implications in remote sensing

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    This database is from the paper: Ding, J., L. Bi, P. Yang, G. W. Kattawar, F. Weng, Q. Liu, and T. Greenwald, 2017: Single-scattering properties of ice particles in the microwave regime: temperature effect on the ice refractive index with implications in remote sensing, Journal of Quantitative Spectroscopy & Radiative Transfer, 190, 26-37. DOI: 10.1016/j.jqsrt.2016.11.026

    Ding-graded modules and strongly Ding-graded modules(Ding分次模和强Ding分次模)

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    研究了分次环R上的Ding分次投射(内射)R-模以及强Ding分次投射(内射)R-模,证明了任意分次环上的Ding分次投射(内射)模类是投射(内射)可解的.研究了强Ding分次投射(内射)R-模与Ding分次投射(内射)R-模之间的关系,以及强Ding分次投射(内射)R-模与非分次的强Ding投射(内射)R-模之间的关系.证明了对有限群分次环R,若M是强Ding投射(内射)R-模,则F(M)是强Ding分次投射(内射)的;若N是强Ding分次投射(内射)R-模,则U(N)是强Ding投射(内射)的

    Glabrinotum Ding 2006

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    Genus <i>Glabrinotum</i> Ding, 2006 <p> <i>Atropidius</i> Emeljanov, 1982: 96. Type species: <i>Gravesteiniella lapilla</i> Emeljanov, 1982, <b>syn</b>. <b>nov</b>. nom. praeocc. <i>Atropidius</i> Chapui, 1874 (Chrysomelidae).</p> <p> <b>Note.</b> <i>Glabrinotum</i> Ding, 2006 placed in synonymy with <i>Atropidius</i> Emeljanov, 1982 according to the synonymy of the type species of these genera mentioned below.</p> <p> The genus <i>Atropidius</i> Emeljanov is a preoccupied name by <i>Atropidius</i> Chapuis in Lacordaire, 1874. <i>Atropidius</i></p> <p> Chapuis 1874. So, <i>Glabrinotum</i> Ding, 2006 should be a valid name for the genus.</p>Published as part of <i>Emeljanov, Alexandr F., 2019, New synonyms and new combinations for some Delphacidae (Hemiptera, Auchenorrhyncha) of Eastern and Central Palaearctic Region, pp. 396-400 in Zootaxa 4559 (2)</i> on pages 396-397, DOI: 10.11646/zootaxa.4559.2.13, <a href="http://zenodo.org/record/2626956">http://zenodo.org/record/2626956</a&gt

    Ding-Jui Ho Oboe Recital Program Notes

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    The program notes of Ding-Jui Ho\ue2s Oboe Recital include four different periods of works: the Baroque period, the Classical period, the Romantic period, and the twentieth century. All the works are important oboe repertoires. Sonata in G Minor for Oboe and Basso Continuo, Wq 135 was C. P. E. Bach\ue2s early work with vigor and lively characters. Mozart\u27s Quartet in F Major for Oboe, Violin, Viola, and Violoncello, KV 370 was written for Friedrich Ramm who was a famous oboist at that time. Saint-Sa\uc3\uabns\ue2s Sonata for Oboe and Piano, Op. 166 was finished in 1921, which was one of the three woodwind sonatas that he wrote in the last year of his life. Dutilleux\ue2s Sonata for Oboe and Piano was his early work, which was commissioned by the Paris Conservatoire. The presentation will introduce the life of four composers, as well as the background and the analysis of these works

    Nanostructured optical fibre tapers and related applications

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    In the last decade, optical fibre tapers have attracted considerable interest because they offer a variety of enabling properties, including large evanescent fields, flexibility, configurability, high confinement, robustness and compactness. These distinctive features have been exploited in a wealth of applications ranging from telecommunication devices to sensors, from optical manipulation to high-Q resonators. Nanostructures on the optical fibre tapers are very promising since the size of the device can be extremely small. With the development of nanostructuring methods, sub-wavelength feature sizes have been achieved. In this thesis, nanostructured optical fibre tapers and some related applications are discussed.Light confinement is limited by diffraction and the minimum spot size is related to the light wavelength. In this thesis, light confinement in two and three dimensions is proposed and achieved with two typologies of nanostructured optical fibre tapers. The first group of devices exploits plasmons excited at the optical fibre tips to obtain high transmissivity, and confine light to a sub-wavelength dimension. Optical fibre tips were designed according to numerical simulations and coated by a layer of gold; an extremely small aperture was then opened at the tip apex. The experimental characterization and simulation results showed their improved transmission efficiency (higher than 10-2) and thermal expansion measurements showed no shape changes could be detected within the accuracy of the system (~2 nm) for 9 mW injected powers. Effective confinements to 10 nm or smaller can be envisaged by decreasing the aperture size and slope angle. Application of this small spot size source can include scanning near-field optical microscope, optical recording, photolithography and bio-sensing.The second group achieves three dimensional light confinement exploiting a Fabry-Perot microcavity formed by a microfibre grating similar to those used in distributed feedback lasers. Microfibres were patterned using a Focused Ion Beam (FIB) system. In this structure, the microcavity provides longitudinal light confinement, whereas air dielectric guiding by the microfibre provides diffraction limited confinement in the other two dimensions. Due to the high refractive index contrast between silica and air, strong reflection can be obtained by only dozens of notches. This device can be used for a wide range of applications, e.g. sensing and triggered single-photon sources.Light confinement in nanostructured optical fibre tapers was exploited in a micrometric thermometer. A compact thermometer based on a broadband microfibre coupler tip showed a dynamic range spanning from room temperature to 1511ºC with a response time of tens of microseconds. This is the highest temperature measured with a silica optical fibre device. An average sensitivity of 11.96 pm/ºC was achieved for a coupler tip with ~2.5 µm diameter. A resolution of 0.66ºC was achieved for a coupler tip diameter of ~12.6 µm. Better resolution can be achieved with smaller size microfibre coupler tips.Optical fibre tapers are commonly used to couple light to selected resonator modes. Here FIB was used to inscribe microgrooves on optical Bottleneck Microresonator (BMR) surfaces to excite selected whispering gallery modes. By monitoring the transmission spectrum of the optical fibre taper, substantial spectral clean-up was obtained in appropriately scarred BMRs. Single high-Q mode operation can be achieved by either using two asymmetrical perpendicular scars or placing the grooves closer to the BMR centre, providing the potential for high performance sensors and other optical devices.Finally, strong three dimensional localization has been achieved in Plasmonic Slot Nano-Resonators (PSNRs) embedded in a gold-coated optical fibre tapers. Different shapes PSNRs, embedded in thin gold metal film coated plasmonic microfibre, were numerically investigated. The intensity enhancement (in excess of 106) and the resonance wavelength depend on both the PSNR and microfibre dimensions. Theoretically and experimentally, the transversal excitation of a rectangular PSNR embedded in a thin gold film coated plasmonic fibre tip was discussed for the first time, and showed high localization and strong enhancement (7.24×103). This device can find a wide range of applications such as surface-enhanced Raman scattering, optical filtering, spectroscopy and bio-sensing

    Ding <i>w</i>-Flat Modules and Dimensions

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    The introduction of w-operation in the class of flat modules has been successful. Let R be a ring. An R-module M is called a w-flat module if [Formula: see text] is GV-torsion for all R-modules N. In this paper, we introduce the w-operation in Gorenstein homological algebra. An R-module M is called Ding w-flat if there exists an exact sequence of projective R-modules … → P1 → P0 → P0 → P1 → … such that M ≅ Im(P0 → P0) and such that the functor HomR(−, F) leaves the sequence exact whenever F is w-flat. Several wellknown classes of rings are characterized in terms of Ding w-flat modules. Some examples are given to show that Ding w-flat modules lie strictly between projective modules and Gorenstein projective modules. The Ding w-flat dimension (of modules and rings) and the existence of Ding w-flat precovers are also studied. </jats:p

    Ding Ganren

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