3,336 research outputs found
UNA ANALISI PER LE POLITICHE DI COMPETITIVITÀ TERRITORIALE. Riferimenti teorici, tecniche di stima e applicazioni.
No full textWithin the weakness of theoretical framework and lack of common definition of
competitiveness, the research aims to propose a useful tool to think and implement
territorial development policy.
We start whit an elucidation of competitiveness concept interpretation, proposing a
multidimensional and multilevel analysis of competitive performance in both regional
(with European and national view) and local level.
The results, emphasizing the peculiar competitiveness characteristics of local system,
allow the reader on think over adequate method and policy
Receensione Bruscaglioni L., Cellini E., Saracino B., Dentro i quartieri di edilizia residenziale pubblica. Una ricerca etnografica per studiare la qualità dell’abitare. Milano: Guerini e Associati. 2016
No full textRecensione Bruscaglioni L., Cellini E., Saracino B., Dentro i quartieri di edilizia residenziale pubblica. Una ricerca etnografica per studiare la qualità dell’abitare. Milano: Guerini e Associati. 201
Cathepsin B in osteoclasts
No full textActive cathepsin B has been found in cell extract and medium of human osteoblast-like cells and MG-63 cells. The released form is stable
at neutral and alkaline pH and, in both cell types, intracellular and extracellular cathepsin B activities are increased by interleukin-1 beta (IL-
1h) and parathyroid hormone (PTH). To evaluate the physiological role of cathepsin B in osteoblasts, we investigated the production and
secretion of this enzyme in normal human synovial fibroblasts and modulation by IL-1h and PTH. Lactate secretion concurrent with release
of cathepsin B and comparable responses in osteoblasts were also examined. Our data show that synovial fibroblasts respond differently to
treatment with the two agents, suggesting a cell-specific regulation of cathepsin B and possible involvement in osteoblast physiology.
Cathepsin B involvement was then evaluated in the activation of plasminogen activator (PA) in MG-63 cells using two specific inhibitors of
cathepsin B, CA074 and CA074-Me, in constitutive conditions and after treatment with IL-1h. As results of PA activity obtained in the
presence of IL-h were in contrast with previous reports, we examined the activities of PA, pro-PA activated with trypsin, and plasmin in cell
extract and media of MG-63 cells after 24-h treatment with IL-1h. Results show that in normal conditions and in the presence of IL-1h,
cathepsin B is involved in the activation of PA. Moreover, IL-1h stimulates PA, pro-PA activated by trypsin, and plasmin activity in medium,
whereas in cell extract it stimulates pro-PA activated by trypsin and plasmin activity. IL-1h has no effect on cell extract-associated PA
Tectonics, climate and deposition/erosion cycles during the Quaternary in Western Sicily
No full textContinental to marine Quaternary deposits outcrop in thin and patchily exposed successions in Western Sicily,
overlying a previously deformed substrate, known as the Neogene-Early Quaternary chain. These deposits are
grouped in sedimentary units bounded by unconformity surfaces. The detected unconformities, often of regional
extent, allows us to define seven main synthems: a) Marsala synthem is a Lower Pleistocene 2-80 m-thick body
of marine/coastal calcarenites; b) Piana di Partinico synthem is made up of 1-5 m thick marine/continental
clastics located on several marine terraces related to sea level highstand phases of Middle Pleistocene (Oxygen
Isotope Stages – OISs - 17-7); c) Polisano synthem consists of aeolian sands, 1-10 m-thick, of late Middle
Pleistocene (OIS 6); d) Barcarello synthem encompasses 1-2 m thick marine/coastal deposits, laterally passing
into 1-5 m thick colluvial deposits, whose age is correlated with the OIS 5; e) Imera Settentrionale synthem is
made up of Middle–Upper Pleistocene 1-3 m-thick fluvial deposits located on river terraces; f) Raffo Rosso
synthem is composed of aeolian sands, colluvial, gravitational and stratified slope deposits (OISs 4-2); g) Capo
Plaia synthem consists of coastal to continental deposits of Holocene age (OISs 2-1).
The processes of deposition or erosion producing sedimentary bodies or unconformity surfaces, respectively,
seem to be triggered by significant environmental changes due to tectonic movements and climatic fluctuations.
The interplay of these factors suggests the following evolution: a Lower Pleistocene block faulting induced
displacements of hundreds of meters allowing the development of marine erosion transgressive surfaces and
shallow-water sedimentation of the Marsala synthem; the interplay between tectonic uplifting and sea level
highstand phases, during Middle-Late Pleistocene, gave rise to several orders of marine and river terraces,
where the Piana di Partinico, Barcarello and Imera Settentrionale synthems deposited. In this period, aeolian and
stratified slope deposits of Polisano and Raffo Rosso synthems were accumulated above non-depositional
surfaces, during cold climatic events; the triggering of strong sheet erosion and sheet flood produced subaerial
erosion surfaces and colluvial deposits of the Piana di Partinico, Barcarello and Raffo Rosso synthems, during
semi-arid climatic events
Geomorphological map of urban area of Palermo (Italy)
No full textThe results of a geomorphological survey carried out in the urban area of Palermo are described. The study
area is located in the northern margin of Western Sicily and is part of the SE-verging Alpine orogenic belt
(Catalano et al., 2013). An E-W mountain range (Sicilian Apennines) is the topographical expression of this
belt (Di Maggio et al., 2017). In the Palermo area, the physical continuity of the mountain range is broken
by a large topographically-depressed coastal area. This area is set on a half-graben and is characterized by a
plain (Conca d’Oro plain), opened to sea and surrounded by wide scarps hundreds of meters tall to the inland.
The wide and tall scarps are abandoned coastal cliffs derived from original fault scarps. Large talus slopes
bound the scarps at their base. A very slight dipping wedge of Calabrian coastal and shallow water clastic
deposits from few to tens of meters thick crops out in the Conca d’Oro plain. These deposits (Marsala synthem,
ISPRA 2013) lie on Meso-Cenozoic rocks with strong angular unconformities. Along the plain, a Middle-
Upper Pleistocene succession of marine terraces develops from 0 m up to 150 m a.s.l. These terraces are
characterized by large and well-preserved polycyclic wave-cut surfaces which in turn are down-cut by some
river valleys from few to ten meters deep. The city of Palermo rises along the marine terrace surfaces and the
river valleys of the Conca d’Oro plain. Over the last 2700 years, the urban area of Palermo has been affected
by remarkable man-made changes to the topographic surface and to the drainage network. The main changes
consist of: filling of river valleys; concreting, diversion and burial of riverbeds; excavation of aqueduct tunnel
(qanat) and underground or open quarries; massive nourishment of the coast areas by means of demolition
materials of the Second World War. Geomorphological setting, man-made changes, and urban development
up to the talus slope expose the city of Palermo a hydraulic, sinkhole, and landslide risks. To facilitate study
on urban planning and environmental risk assessment, a geomorphological map of the urban area of Palermo
has been achieved through field surveys, multitemporal analysis of aerial photographs and topographic map,
consultation of historical documents, and stratigraphic and topographic reconstructions from numerous wells
<b>I confini della lettera. Pratiche epistolari e reti di comunicazione nell'Italia tardomedievale</b>
No full textAtti della giornata di studi, Isernia, 9 maggio 2008
MANIFESTAZIONI ADDOMINALI E GONADICHE NELLA PORPORA DI SCHÖNLEIN-HENOCH: ESTRAPOLAZIONE DALLA CASISTICA DELLA CLINICA PEDIATRICA DI PALERMO
No full text
- …
