3,170 research outputs found

    Business Model Innovation of JF Logistics Company

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    摘要 随着全球化经济的发展,市场竞争变得越来越复杂。信息时代使得物流供应链管理已上升到企业的战略管理高度。在这样的背景下,本文应用翁君奕老师的介观商务模式创新观点,对JF物流公司所处行业现状进行剖析,重新审视了外部客户市场以及内部自身情况,找出了JF物流公司自身的优势,并结合外部市场客户的需求,提出了“为客户提供个性化的集物流、资金流、信息流于一体的供应链物流服务”这一价值主张,并在此基础上,重新定位客户市场,创新服务产品,理顺内部管理架构和业务流程以支撑和保持这一价值主张。文中同时以例证来说明依据新价值主张所创新的服务产品给JF物流公司所带来的变化,以此说明通过商务模式创新来实行自身的战略...Abstract With the development of the global economy, the competition in market becomes more complicated. In the era of information, logistics and supply chain management is regarded as important as part of the company strategy. Under such background , the author of this essay uses the concept of “JieGuan Business Model Innovation” proposed by Professor Weng Junyi of Xiamen University, and analy...学位:管理学硕士院系专业:管理学院高级经理教育中心(EMBA项目)_管理经济学学号:X200615614

    Temporal and spatial variability in speakers with Parkinson's Disease and Friedreich's Ataxia

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    Speech variability in groups of speakers with Parkinson's disease (PD) and with Friedreich's ataxia was compared with healthy controls. Speakers repeated the same phrase 20 times at one of two rates (fast or habitual). A non-linear analysis of variability was performed which used some of the principles behind the spatio-temporal index (STI). The STI usually employs variation in lip displacement over repetitions of the same utterance and a linear analysis of such signals is conducted to represent the combined variation in spatial and temporal control. When working with patients, audio measures (here we used speech energy) are preferred over kinematics ones as they are minimally disruptive to speech. Non-linear methods allow spatial variability to be estimated separately from temporal variability. The results are tentatively interpreted as showing that PD speakers were distinguished from healthy control speakers in spatial variability and ataxic speakers were distinguished from controls in temporal variability. These findings are consistent with the speech symptoms reported for these disorders. We conclude that the non-linear analysis using the speech energy measure is worth investigating further as it is potentially revealing of the differences underlying these two pathologies

    Mechanical Performance of Jute Fiber-Reinforced Micaceous Clay Composites Treated with Ground-Granulated Blast-Furnace Slag

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    The combined capacity of Jute Fibers (JF), the reinforcement, and Ground-Granulated Blast-Furnace Slag (GBFS), the binder, was examined as a sustainable solution towards ameliorating the inferior engineering properties of micaceous clays. A total of sixteen JF + GBFS mix designs, i.e., JF (% by total mass) = {0, 0.5, 1.0, 1.5} and GBFS (% by total mass) = {0, 3, 6, 9}, were tested for unconfined compression (UC) strength; for those mix designs containing GBFS, curing was allowed for 7 and 28 days prior to testing. Scanning electron microscopy (SEM) studies were also carried out to observe the evolution of fabric in response to JF, GBFS and JF + GBFS amendments. The greater the JF content the higher the developed strength and stiffness up to 1% JF, beyond of which the effect of JF-reinforcement led to some adverse results. The JF inclusions, however, consistently improved the ductility and toughness of the composite. The addition of GBFS to the JF-reinforced samples improved the soil–fiber connection interface, and thus led to further improvements in the composite’s strength, stiffness and toughness. The mix design “1% JF + 9% GBFS” managed to satisfy ASTM’s strength criterion and hence was deemed as the optimum choice in this investigation. Finally, a non-linear, multivariable regression model was developed and validated to quantify the peak UC strength as a function of the composite’s index properties. The proposed model contained a limited number of fitting parameters, all of which can be calibrated by little experimental effort, and thus implemented for preliminary design assessments

    Additional file 6 of Prevalence of chronic cough in China: a systematic review and meta-analysis

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    Additional file 6. Fig. S1. Distribution of children with chronic cough across Mainland China. NOTE: Red star in the map represents Beijing City. The map was developed in XL Toolbox NG by ourselves, without the conflict of copyright. Fig. S2. Pooled chronic cough prevalence of adults stratified by region. Abbreviations: CI, confidence intervals. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S3. Pooled chronic cough prevalence of adults stratified by diagnostic criteria. Abbreviations: CI, confidence intervals. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S4. Pooled chronic cough prevalence of adults stratified by year of publication. Abbreviations: CI, confidence intervals. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S5. Pooled chronic cough prevalence of adults stratified by age. Abbreviations: CI, confidence intervals. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S6. Pooled chronic cough prevalence of adults stratified by sampling methods. Abbreviations: CI, confidence intervals. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S7. Pooled chronic cough prevalence of adults stratified by sample size. Abbreviations: CI, confidence intervals; ES, Effect Size. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S8. Pooled chronic cough prevalence of adults stratified by prevalence definitions. Abbreviations: CI, confidence intervals; ES, Effect Size. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S9. Pooled chronic cough prevalence of adults stratified by chronic cough definitions. Abbreviations: CI, confidence intervals; ES, Effect Size. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S10. Pooled chronic cough prevalence of adults stratified by quality of articles assessed by AHRQ. Abbreviations: CI, confidence intervals; ES, Effect Size. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S11. Pooled chronic cough prevalence of children stratified by region. Abbreviations: CI, confidence intervals. NOTE: The four author labels of ZHANG JF 2002 are from the same literature. Fig. S12. Pooled chronic cough prevalence of children stratified by diagnostic criteria. Abbreviations: CI, confidence intervals. NOTE: The four author labels of ZHANG JF 2002 are from the same literature. Fig. S13. Pooled chronic cough prevalence of children stratified by year of publication. Abbreviations: CI, confidence intervals. NOTE: The four author labels of ZHANG JF 2002 are from the same literature. Fig. S14. Pooled chronic cough prevalence of children stratified by sample size. Abbreviations: CI, confidence intervals. NOTE: The four author labels of ZHANG JF 2002 are from the same literature. Fig. S15. Pooled chronic cough prevalence of children stratified by chronic cough definitions. Abbreviations: CI, confidence intervals; ES, Effect Size. NOTE: The four author labels of ZHANG JF 2002 are from the same literature. Fig. S16. Pooled chronic cough prevalence of children stratified by quality of articles assessed by AHRQ. Abbreviations: CI, confidence intervals. NOTE: The four author labels of ZHANG JF 2002 are from the same literature. Fig. S17. Pooled chronic cough prevalence of children stratified by prevalence definitions. Abbreviations: CI, confidence intervals. NOTE: The four author labels of ZHANG JF 2002 are from the same literature. Fig. S18. Funnel plot for prevalence in studies of adults for chronic cough. Fig. S19. Sensitivity analysis for prevalence in studies of adults for chronic cough. Abbreviations: CI, confidence intervals. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S20. The prevalence of chronic cough in adults after exclusion of the nationwide study (Li JC 2018). Abbreviations: CI, confidence intervals. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S21. The prevalence of chronic cough in adults after exclusion of the low prevalence study (ZHANG JF 1999). Abbreviations: CI, confidence intervals. NOTE: The two author labels of ZHANG JF 1999 are from the same literature, and the two author labels of Venners 2001 are from the same literature. Fig. S22. Funnel plot for prevalence in studies of children for chronic cough. Fig. S23. Sensitivity analysis for prevalence in studies of children for chronic cough. Abbreviations: CI, confidence intervals. NOTE: The four author labels of ZHANG JF 2002 are from the same literature. Fig. S24. Pooled prevalence of chronic cough in China (including adults and children). Abbreviations: CI, confidence intervals. NOTE: The three author labels of ZHANG JF 1999 are from the same literature, the two author labels of Venners 2001 are from the same literature, and the four author labels of ZHANG JF 2002 are from the same literature

    Joint faulting behaviour of innovative short concrete slabs

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    Pavements are one of the largest assets of a city and their functional condition (ride quality) is priority for their clients. In jointed plain concrete pavements (JPCPs), the presence of joint faulting (JF) reduces the ride quality. Today, short slabs are available as a cost-effective JPCP innovation. The objective of this paper is to analyse the JF behaviour of JPCPs with short slabs. For this, a deterioration model to predict it and trends of JF observed in short slabs of Chile and the United States are considered. The HDM-4 model always yields lower JF per joint in short slabs than in traditional ones. However, real-world short slabs show not only lower JF per joint (that the modelled JF), but also that more joints do not necessarily mean more JF per length of pavement that affect the ride quality. One of the relevant explanatory factors for it is the radical reduction of crack width at joints, which produces a fundamental increase of the load transfer efficiency. To maintain favourable behaviour observed in the field it is recommended to assure joint activation and to provide adequate stiffness of the layers below the short slabs.Pavement Engineerin

    Metabolism of archidonic acid by 5-lipoxygenase in guinea-pig lung

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    PT: J; CR: BURKA JF, 1981, PROSTAG OTH LIPID M, V22, P683 BURKA JF, 1983, J PHARMACOL EXP THER, V225, P427 PARKER CW, 1982, BIOCHEM BIOPH RES CO, V109, P1011 SAAD MH, 1983, PROSTAGLANDINS, V25, P741 SAAD MH, 1984, EUR J PHARMACOL, V100, P13 SCHIANTARELLI P, 1981, EUR J PHARMACOL, V73, P363; NR: 6; TC: 6; J9: PROSTAGLANDINS; PG: 2; GA: TU225Source type: Electronic(1

    The Relation between Treated Maternal Urinary Tract Infection and Adverse Maternal, Prenatal Outcomes in Pregnant Women of Ardabil, Iran

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    Background and Objective: ­ Urinary tract infection is one of the most common bacterial infections during pregnancy and has also been implicated as a risk factor for adverse maternal and prenatal ­­outcomes. The aim of our study was to determine the relation between maternal urinary tract infection and adverse maternal, prenatal outcomes in pregnant women of Ardabil, Iran. Material and Methods: ­ This retrospective-case-control study was conducted on­ prenatal file records of pregnant women in Ardabil (2011). ­ ­The pregnant women ­who had a positive urine culture in their prenatal files­ (N= 211) ­were considered as a case ­group and ­232­ ones without urinary tract infection as a control. Using a research- made questionnaire, the data related to present pregnancy and prenatal information was collected and analyzed by KrusKal Wallis, Chi- Square and Fisher statistical tests. Results­: Maternal age of under 25 (%61.6 vs. 56.5), body mass index of more than 30 (%18.3 vs. 15.6), primigravida (%55 vs. 48.8), hypertension (%2.4 vs. 1.3), hyperemesis Gravidarum (%14.8 vs. 12.6), frequency ­and dysuria ­(%1.9 vs. 0.9), low birth weight (%95.4 vs. 93.2), congenital malformation (%3.5 vs. 1.8), artificial milk feeding (%6.5 vs. 2.7), neonatal death (%0.9 vs. 0.0) are higher in urinary infection group, however the differences are not statistically significant. Other maternal and prenatal adverse outcomes such as diabetes, pre-eclampsia , hemoglobin level, prematurity, abortion and stillbirth have not significant relation with urinary infection. Conclusion: Because of low level of adverse maternal or prenatal outcomes reported in our study, we conclude that screening and treatment of urinary tract infection in Ardabil health service is ­appropriate; therefore, ­no change is needed for present ­screening­ or treatment processes

    Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages

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    Genetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy. To determine whether vascular endothelial growth factor A (VEGF-A) produced by tumor-associated macrophages regulated the onset of the angiogenic switch, a genetic approach was used to restore expression of VEGF-A into tumors at the benign stages. This stimulated formation of a high-density vessel network and in macrophage-depleted mice, was followed by accelerated tumor progression. The expression of VEGF-A led to a massive infiltration into the tumor of leukocytes that were mostly macrophages. This study suggests that macrophage-produced VEGF regulates malignant progression through stimulating tumor angiogenesis, leukocytic infiltration and tumor cell invasion

    Effects of calcium channel blockers on pharmacologically induced contractions of rainbow trout (Oncorhynchus mykiss) intestine

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    PT: J; CR: BERRIDGE MJ, 1988, P R SOC LONDON B, V234, P359 BRINK C, 1981, J PHARMACOL EXP THER, V217, P592 BURKA JF, 1989, ANIMAL DRUGS FOOD SA, P110 BURKA JF, 1989, CAN J PHYSIOL PHARM, V67, P477 BURKA JF, 1990, IN PRESS CAN J PHYSL, V68 BURNSTOCK G, 1958, BRIT J PHARMACOL CHE, V13, P216 BURNSTOCK G, 1959, Q J MICROSC SCI, V100, P199 CARPENTER JR, 1986, J PHARMACOL METHOD, V15, P283 COOK DA, 1977, FED PROC, V36, P2584 HOAR WS, 1967, LABORATORY COMPANION ISHIKAWA S, 1985, BRIT J PHARMACOL, V86, P789 JANIS RA, 1983, BIOCHEM PHARMACOL, V32, P3499 JANIS RA, 1983, J MED CHEM, V26, P775 KARAKI H, 1988, LIFE SCI, V42, P111 KITCHEN I, 1984, TXB INVITRO PRACTICA LEFF P, 1987, J PHARMACOL EXP THER, V240, P284 SAIDA K, 1983, BLOOD VESSELS, V20, P105 SCHWARTZ A, 1984, ANNU REV MED, V35, P325 SMALL RC, 1982, BRIT J PHARMACOL, V77, P45 SPEDDING M, 1988, ANN NY ACAD SCI, V522, P248 VANBREEMEN C, 1979, PHARMACOL REV, V30, P167 WOLOWYK MW, 1987, J THERM BIOL, V12, P87; NR: 22; TC: 2; J9: FISH PHYSIOL BIOCHEM; PG: 7; GA: EG368Source type: Electronic(1
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