2,855 research outputs found

    Updates in the flora of the Maltese Islands (Central Mediterranean)

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    During the last 5 years, this author has been involved in the research and exploration of the flora of the Maltese islands in order to create and update the website http://www.maltawildplants.com. This paper consists of several important discoveries of new populations of very rare or endangered floral species for the Maltese Islands which were recorded during field surveys to collect material for this website. It also includes the species Calendula bicolor Rafin., which is a new record for the Maltese islands.peer-reviewe

    Flora Tristan Life Stories

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    Flora Tristan is best known as a nineteenth century French social critic and reformer. Her writings can be seen as a precursor to Marxism and Feminism. Flora Tristan: Life Sories by Susan Grogan, investigates the life of Flora Tristan through an exploration of the way she represented herself in her own writings. The author also examines the portrayal of Flora Tristan in paintings and literature. Rather than adopting a chronological approach, the author surveys the personae of Flora Tristan through thematic chapters on her roles as author, socialist, traveller and "Mother of the Workers". She places Flora Tristan in the context of contemporary debates and ideas, adding to our understanding of the times in which Flora Tristan lived. Flora Tristan: Life Stories argues that Flora Tristan's self-representations were attempts to claim a role of authority and significance not open to women in the nineteenth century. This authoritative study also engages with attempts to re-evaluate the writing of biography and to explore the meaning of an individual life in historical context.Book Cover -- Title -- Copyright -- ContentsFlora Tristan is best known as a nineteenth century French social critic and reformer. Her writings can be seen as a precursor to Marxism and Feminism. Flora Tristan: Life Sories by Susan Grogan, investigates the life of Flora Tristan through an exploration of the way she represented herself in her own writings. The author also examines the portrayal of Flora Tristan in paintings and literature. Rather than adopting a chronological approach, the author surveys the personae of Flora Tristan through thematic chapters on her roles as author, socialist, traveller and "Mother of the Workers". She places Flora Tristan in the context of contemporary debates and ideas, adding to our understanding of the times in which Flora Tristan lived. Flora Tristan: Life Stories argues that Flora Tristan's self-representations were attempts to claim a role of authority and significance not open to women in the nineteenth century. This authoritative study also engages with attempts to re-evaluate the writing of biography and to explore the meaning of an individual life in historical context.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries

    A comparison of the moss floras of Chile and New Zealand

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    Chile and New Zealand share a common stock of 181 species of mosses in 94 genera and 34 families. This number counts for 23.3% of the Chilean and 34.6% of the New Zealand moss flora. If only species with austral distribution are taken into account, the number is reduced to 113 species in common, which is 14.5% of the Chilean and 21.6% of the New Zealand moss flora. This correlation is interpreted in terms of long distance dispersal resp. the common phytogeographical background of both countries as parts of the palaoaustral floristic region and compared with disjunct moss floras of other continents as well as the presently available molecular data

    Defining indigenous plants: some problematic species from Norfolk Island

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    Defining indigenous species may at first appear straight forward; most botanical texts provide similar definitions. The consistent requirement of such definitions is the lack of human intervention in the occurrence of the species within the area under consideration. Islands around the world have been invaded by plant species brought to their shores by humans. They are also places where self-introduced species can be continually arriving, as they have done for millennia. Scrutiny of the situation on Norfolk Island (1200 km east of Australia) finds that the distinction between indigenous and introduced taxa is sometimes unclear. There is also inconsistency regarding the acceptance of self-introduced species as indigenous. This paper explores these issues and notes that they are more important than idle botanical curiosity, because control of introduced (weed) species is a major area of activity in managing protected natural areas

    Control of intestinal hyperplasia by the PAR-4/LKB1 kinase in Caenorhabditis elegans

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    La protéine de polarité et suppresseur de tumeur PAR-4/LKB1 est considérée comme un régulateur majeur de la physiologie intestinale. Son activation ectopique est suffisante pour induire la formation de microvillosités apicales dans des lignées cellulaires intestinales cancéreuses, tandis que des mutations du gène lkb1 sont responsables du syndrome de Peutz-Jeghers (PJS) dans lequel les patients développent des polypes intestinaux bénins. Il est crucial de mieux caractériser son rôle dans les entérocytes in vivo. Pour ce faire, nous avons utilisé la microscopie confocale et électronique pour observer l'épithélium intestinal chez les embryons C. elegans mutants par-4. De manière surprenante, PAR-4 n'est pas strictement requise pour la polarité intestinale et la formation de microvillosités. Cependant, les embryons par-4 présentent des entérocytes supplémentaires, ce qui entraîne des défauts dans l'architecture du tissu, notamment des déformations de la lumière. Des expériences de lignage ont révélé que le nombre excessif d’entérocytes présents dans les embryons par-4 n’est pas induit par une hyperprolifération cellulaire, mais par des défauts de spécification. Alors que dans les embryons contrôles, les entérocytes proviennent tous du blastomère E, dans les embryons par-4, des entérocytes supplémentaires naissent également à partir du blastomère C. Ce travail révèle une nouvelle fonction nécessaire de PAR-4 pour restreindre l’acquisition du destin intestinal au lignage E.The polarity and tumor suppressor protein PAR-4/LKB1 is thought to be a major regulator of intestinal physiology. Its ectopic activation is indeed sufficient to induce apical microvilli formation in intestinal cancer cell lines. Moreover, mutations in the lkb1 gene are responsible for the Peutz-Jeghers syndrome (PJS) in which patients develop benign intestinal polyps. As this master kinase acts via various signaling pathways, it is crucial to better characterize its role in enterocytes in vivo. To do so, we used confocal and electron microscopy to observe the intestinal epithelium in C. elegans par-4 mutant embryos. Surprisingly, PAR-4 is not strictly required for intestinal polarity and microvilli formation. However, par-4 mutant embryos display extra enterocytes, which lead to striking defects in tissue architecture, notably to strong lumen deformations. Lineage experiments revealed that PAR-4 does not control the number of enterocytes by regulating cell proliferation, but rather by controlling cell fate specification during embryogenesis. While in wild type embryos intestinal cells exclusively arise from the E blastomere, in par-4 mutants additional enterocytes arise from the C blastomere. Thus, PAR-4 prevents intestinal specification in the C lineage of wild type embryos. This work reveals a novel function of PAR-4 in the regulation of cell fate specification during embryogenesis. This appears to be essential to prevent intestinal hyperplasia in C. elegans

    Contrôle de l’hyperplasie intestinale par la kinase PAR-4/LKB1 chez Caenorhabditis elegans

    No full text
    The polarity and tumor suppressor protein PAR-4/LKB1 is thought to be a major regulator of intestinal physiology. Its ectopic activation is indeed sufficient to induce apical microvilli formation in intestinal cancer cell lines. Moreover, mutations in the lkb1 gene are responsible for the Peutz-Jeghers syndrome (PJS) in which patients develop benign intestinal polyps. As this master kinase acts via various signaling pathways, it is crucial to better characterize its role in enterocytes in vivo. To do so, we used confocal and electron microscopy to observe the intestinal epithelium in C. elegans par-4 mutant embryos. Surprisingly, PAR-4 is not strictly required for intestinal polarity and microvilli formation. However, par-4 mutant embryos display extra enterocytes, which lead to striking defects in tissue architecture, notably to strong lumen deformations. Lineage experiments revealed that PAR-4 does not control the number of enterocytes by regulating cell proliferation, but rather by controlling cell fate specification during embryogenesis. While in wild type embryos intestinal cells exclusively arise from the E blastomere, in par-4 mutants additional enterocytes arise from the C blastomere. Thus, PAR-4 prevents intestinal specification in the C lineage of wild type embryos. This work reveals a novel function of PAR-4 in the regulation of cell fate specification during embryogenesis. This appears to be essential to prevent intestinal hyperplasia in C. elegans.La protéine de polarité et suppresseur de tumeur PAR-4/LKB1 est considérée comme un régulateur majeur de la physiologie intestinale. Son activation ectopique est suffisante pour induire la formation de microvillosités apicales dans des lignées cellulaires intestinales cancéreuses, tandis que des mutations du gène lkb1 sont responsables du syndrome de Peutz-Jeghers (PJS) dans lequel les patients développent des polypes intestinaux bénins. Il est crucial de mieux caractériser son rôle dans les entérocytes in vivo. Pour ce faire, nous avons utilisé la microscopie confocale et électronique pour observer l'épithélium intestinal chez les embryons C. elegans mutants par-4. De manière surprenante, PAR-4 n'est pas strictement requise pour la polarité intestinale et la formation de microvillosités. Cependant, les embryons par-4 présentent des entérocytes supplémentaires, ce qui entraîne des défauts dans l'architecture du tissu, notamment des déformations de la lumière. Des expériences de lignage ont révélé que le nombre excessif d’entérocytes présents dans les embryons par-4 n’est pas induit par une hyperprolifération cellulaire, mais par des défauts de spécification. Alors que dans les embryons contrôles, les entérocytes proviennent tous du blastomère E, dans les embryons par-4, des entérocytes supplémentaires naissent également à partir du blastomère C. Ce travail révèle une nouvelle fonction nécessaire de PAR-4 pour restreindre l’acquisition du destin intestinal au lignage E

    Contrôle de l’hyperplasie intestinale par la kinase PAR-4/LKB1 chez Caenorhabditis elegans

    No full text
    The polarity and tumor suppressor protein PAR-4/LKB1 is thought to be a major regulator of intestinal physiology. Its ectopic activation is indeed sufficient to induce apical microvilli formation in intestinal cancer cell lines. Moreover, mutations in the lkb1 gene are responsible for the Peutz-Jeghers syndrome (PJS) in which patients develop benign intestinal polyps. As this master kinase acts via various signaling pathways, it is crucial to better characterize its role in enterocytes in vivo. To do so, we used confocal and electron microscopy to observe the intestinal epithelium in C. elegans par-4 mutant embryos. Surprisingly, PAR-4 is not strictly required for intestinal polarity and microvilli formation. However, par-4 mutant embryos display extra enterocytes, which lead to striking defects in tissue architecture, notably to strong lumen deformations. Lineage experiments revealed that PAR-4 does not control the number of enterocytes by regulating cell proliferation, but rather by controlling cell fate specification during embryogenesis. While in wild type embryos intestinal cells exclusively arise from the E blastomere, in par-4 mutants additional enterocytes arise from the C blastomere. Thus, PAR-4 prevents intestinal specification in the C lineage of wild type embryos. This work reveals a novel function of PAR-4 in the regulation of cell fate specification during embryogenesis. This appears to be essential to prevent intestinal hyperplasia in C. elegans.La protéine de polarité et suppresseur de tumeur PAR-4/LKB1 est considérée comme un régulateur majeur de la physiologie intestinale. Son activation ectopique est suffisante pour induire la formation de microvillosités apicales dans des lignées cellulaires intestinales cancéreuses, tandis que des mutations du gène lkb1 sont responsables du syndrome de Peutz-Jeghers (PJS) dans lequel les patients développent des polypes intestinaux bénins. Il est crucial de mieux caractériser son rôle dans les entérocytes in vivo. Pour ce faire, nous avons utilisé la microscopie confocale et électronique pour observer l'épithélium intestinal chez les embryons C. elegans mutants par-4. De manière surprenante, PAR-4 n'est pas strictement requise pour la polarité intestinale et la formation de microvillosités. Cependant, les embryons par-4 présentent des entérocytes supplémentaires, ce qui entraîne des défauts dans l'architecture du tissu, notamment des déformations de la lumière. Des expériences de lignage ont révélé que le nombre excessif d’entérocytes présents dans les embryons par-4 n’est pas induit par une hyperprolifération cellulaire, mais par des défauts de spécification. Alors que dans les embryons contrôles, les entérocytes proviennent tous du blastomère E, dans les embryons par-4, des entérocytes supplémentaires naissent également à partir du blastomère C. Ce travail révèle une nouvelle fonction nécessaire de PAR-4 pour restreindre l’acquisition du destin intestinal au lignage E

    A contribution to the Campylopus flora of Chile

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    A key to the species of Campylopus known from Chile is given, completed by records of Campylopodioideae of the author in southern Chile. Campylopus acuminatus Mitt. var. kirkii (Mitt.) J.-P. Frahm is reported for the first time for Chile

    Growth and physiology of carbon limited "Penicillium ochrochloron" cultures in dependence of the illumination conditions

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    Author: Flora Burgstaller, B.Sc.Masterarbeit Universität Innsbruck 202
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