268 research outputs found
Forma maschile, genere femminile: si presentano le donne
No full textSi presenta qui la prima indagine che raccoglie dati empirici sugli usi linguistici effettivi dell’italiano in contesti reali sull'uso del genere grammaticale.L'analisi si basa su due piccoli corpora: uno di testi scritti, in cui le donne si autopresentano e uno di testi parlati in cui abbiamo sia autopre-sentazioni da parte delle donne sia donne presentate da altre donne o uomini. La scelta del genere grammaticale si intreccia con variabili di livello diamesico e diafasico, che hanno a che fare con gli aspetti relazionali e sociali della comuni-cazione linguistica, a dimostrazione del fatto che si tratta di una scelta condizionata dai rapporti interpersonali e culturali, e non semplicemente dalla grammatica della lingua. Per questo motivo abbiamo indagato le scelte linguistiche delle donne, riservando un’attenzione particolare a come le donne parlano di se stesse e in particolare quanto spazio danno al genere femminile quando si tratta del loro mondo professionale
Upside-down positioning of a peri-interventional cava filter during endovascular thrombectomy of a septic superior vena cava thrombosis
No full textA 43-year-old male patient with advanced colon carcinoma presented with disseminated staphylococcus aureus bacteremia and central venous catheter associated septic thrombosis of the superior vena cava. Despite appropriate antimicrobial therapy and surgical debridement of distant foci, bacteremia persisted, so an endovascular thrombectomy was performed. Contrary to the usual application, the Capturex® peri-interventional cava filter was positioned upside down, in the direction of the blood flow, in the superior vena cava to prevent septic embolism during mechanical thrombectomy. The wall-adherent septic thrombus was mechanically detached using a RAT fragmentation basket® followed by Aspirex® rotational thrombectomy. Final phlebography showed complete thrombus removal. Small thrombus fragments could be demonstrated in the filter after retrieval. The adapted technique of a reverse positioning of the Capturex® filter in the superior vena cava seems feasible and effective
Effects of neurosteroids on a model membrane including cholesterol: A micropipette aspiration study
No full textAmphiphilic molecules supposed to affect membrane protein activity could strongly interact also with the lipid component of the membrane itself. Neurosteroids are amphiphilic molecules that bind to plasma membrane receptors of cells in the central nervous system but their effect on membrane is still under debate. For this reason it is interesting to investigate their effects on pure lipid bilayers as model systems. Using the micropipette aspiration technique (MAT), here we studied the effects of a neurosteroid, allopregnanolone (3α,5α-tetrahydroprogesterone or Allo) and of one of its isoforms, isoallopregnanolone (3β,5α-tetrahydroprogesterone or isoAllo), on the physical properties of pure lipid bilayers composed by DOPC/bSM/chol. Allo is a well-known positive allosteric modulator of GABAA receptor activity while isoAllo acts as a non-competitive functional antagonist of Allo modulation. We found that Allo, when applied at nanomolar concentrations (50-200 nM) to a lipid bilayer model system including cholesterol, induces an increase of the lipid bilayer area and a decrease of the mechanical parameters. Conversely, isoAllo, decreases the lipid bilayer area and, when applied, at the same nanomolar concentrations, it does not affect significantly its mechanical parameters. We characterized the kinetics of Allo uptake by the lipid bilayer and we also discussed its aspects in relation to the slow kinetics of Allo gating effects on GABAA receptors. The overall results presented here show that a correlation exists between the modulation of Allo and isoAllo of GABAA receptor activity and their effects on a lipid bilayer model system containing cholesterol
LEGGERE E COMPRENDERE UNA PROPOSTA PER IL RECUPERO E IL POTENZIAMENTO DELLE ABILITÀ DI LETTURA E COMPRENSIONE DEL TESTO
No full textLeCo: una proposta per il recupero e il potenziamento delle abilità di lettura e comprensione del testo
No full textRegional anaesthesia for caesarean section in severe preeclampsia: spinal anaesthesia is the preferred choice
No full textPart of the Portfolio Thesis by Geoffrey H. Sharwood-Smith: The inferior vena caval compression theory of hypotension in obstetric spinal anaesthesia: studies in normal and preeclamptic pregnancy, a literature review and revision of fundamental concepts, available at http://hdl.handle.net/10023/1815Standard textbooks advocate epidural rather than spinal anaesthesia for caesarean section in severe preeclampsia. The basis for this recommendation is the theoretical risk of severe hypotension but no published scientific studies have been identified to support this assertion. We therefore designed a prospective study to compare spinal versus epidural anaesthesia in severely pre-eclamptic patients requiring hypotensive therapy. Following ethics committee approval, 28 women with preeclampsia requiring hypotensive medication who were scheduled for urgent (not emergency) or elective caesarean section consented to receive epidural or spinal anaesthesia by random assignment. Seven patients were excluded due to protocol violations. Four of these were in the epidural group of which two were excluded due to inadequate analgesia. No spinal patient was excluded because of inadequate analgesia. Mean ephedrine dosage was 5.2 mg (range 0–24 mg) in the spinal group and 6.3 mg (range 0–27 mg) in the epidural group. Six of the 11 patients in the spinal group required no ephedrine as did five of 10 in the epidural group. One patient in the spinal group suffered from mild intraoperative pain. By contrast in the epidural group three patients had mild pain and four others had pain severe enough to warrant intraoperative analgesia. There were no differences in neonatal outcomes. These findings support recent studies suggesting the safety and efficacy of spinal anaesthesia in this group of patients.Publisher PD
Nuove scoperte nel castello di Rontana
No full textA new season of archaeological excavations has been undertaken last summer, inside
the castle of Rontana (Brisighella, Ra), by the Department of History, Cultures,
Civilization(Disci) of Alma Mater Studiorum - University of Bologna, thanks to a collaboration
with Parco regionale della Vena del Gesso Romagnola, Comune di Brisighella and
the support of Cassa di Risparmio di Ravenna Foundation. During these researches,
houses, wooden defensive wall, a church and several burials have been discovered
under a deep layer of destruction due to a military campaign conducted in AD 1591,
by Pope’ army to defeat ‘latrones’, in other words bandits, settled inside the castle. The
excavations were carried out for ten years and a new archaeological site is now open to
the community, to preserve and study local and European heritage
LEGGIBILITÀ E COMPRENSIBILITÀ: UN BINOMIO NECESSARIO
No full textQuesto contributo presenta i primi risultati di un lavoro esplorativo di calcolo e analisi della leggibilità con l’indice GULPEASE (1988) di testi appartenenti al corpus Leggere e Comprendere (LeCo), pubblicato su www.studiumdipsum.it, creato dal Dipartimento di Studi Umanistici dell’Università di Salerno. LeCo è il risultato di due progetti, L.A.M.P (2016) e Alpha-Mente (2021) centrati sul recupero e la valorizzazione delle abilità di lettura e comprensione per monitorare e valutare le competenze di alfabetizzazione degli studenti della scuola secondaria (cfr. l’articolo di Voghera et al. in questa monografia). L’obiettivo è quello di misurare e valutare il necessario legame tra leggibilità/lettura e comprensibilità dei testi nel complesso processo di comprensione per identificare la reale leggibilità dei testi in LeCo e renderli più accessibili agli studenti con bisogni educativi speciali. In questo contributo vengono presentati i principali aspetti della complessità della leggibilità e comprensibilità di un testo (§ 2) e gli indici di leggibilità più comuni (§ 3). In primo luogo, l’analisi dell’indice GULPEASE si concentra sul corpus LeCo; in secondo luogo, sulle possibili strategie per semplificare e facilitare i testi, soprattutto per gli studenti con bisogni educativi speciali (§ 4); e, infine, sui possibili sviluppi futuri di ricerca e studio (§ 6).
Readability and comprehensibility: a necessary combination
This paper presents the first results of an exploratory work of calculation and analysis of the readability with the GULPEASE Index (1988) on the texts from the corpus “Leggere e Comprendere” (LeCo), published at www.studiumdipsum.it, created by the Department of Humanities Studies of the University of Salerno. LeCo is the result of two projects, L.A.M.P (2016) and Alpha-Mente (2021). They focused on the recovery and enhancement of reading and comprehension skills to monitor and evaluate the literacy skills of secondary school students (cfr. the article by Voghera et al. in this volume). The goal was to measure and evaluate the necessary link between the legibility/readability and comprehensibility of texts in the complex process of understanding, to identify the real readability of the texts in LeCo and to make them more accessible to students with special educational needs. We present the main aspects of the complexity of the readability and comprehensibility of a text (§ 2) and the most common readability indexes (§ 3). Firstly, the analysis of the GULPEASE Index focuses on the LeCo corpus; secondly on the possible strategies for simplifying and facilitating texts, especially for students with special educational needs (§ 4); and, finally, on the possible future research and study developments (§ 6)
The inferior vena caval compression theory of hypotension in obstetric spinal anaesthesia: studies in normal and preeclamptic pregnancy, a literature review and revision of fundamental concepts
No full textFull metadata records and copyright statements for publications contained in this portfolio thesis are available at the identifiers listedThree clinical investigations together with a combined editorial and review of the cardiovascular physiology
of spinal anaesthesia in normal and preeclamptic pregnancy form the basis of a thesis to be submitted for the
degree of Doctor of Medicine at the University of St Andrews. First, the longstanding consensus that spinal
anaesthesia could cause severe hypotension in severe preeclampsia was examined using three approaches.
The doses of ephedrine required to maintain systolic blood pressure above predetermined limits were first
compared in spinal versus epidural anaesthesia. The doses of ephedrine required were then similarly studied
during spinal anaesthesia in preeclamptic versus normal control subjects. The principal outcome of these
studies, that preeclamptic patients were resistant to hypotension after a spinal anaesthetic, was then further
investigated by studying pulse transit time (PTT) changes in normal versus preeclamptic pregnancy. PTT
was explored both as beat-to-beat monitor of cardiovascular function and also as an indicator of changes in
arterial stiffness. The cardiovascular physiology of obstetric spinal anaesthesia was then reviewed in the light
of the three clinical investigations, developments in reproductive vascular biology and the regulation of
venous capacitance. It is argued that the theory of a role for vena caval compression as the single cause of
spinal anaesthetic induced hypotension in obstetrics should be revised
Vivere e morire nel castello di Rontana. Lo sfruttamento del Gesso in un insediamento di fondazione medievale della Vallata Del Lamone
No full textThe castle of Rontana is one of the earliest and most important fortified settlement in Lamone’s valley,
and was chosen as a pilot-excavation to better understand the dynamics of this type of settlements in
Romagna, since our first dig-season in 2007. The surveys showed the main features of this settlement
and showed the close relationship between the rural population and Gypsum bedrock from the earli-
est phase of its occupation. Mt. Rontana’s Gypsum (Messinian Gypsum outcrop of the Vena del Gesso
romagnola, Northern Italy) was used by the community of the castle to fortify the settlement, to live
there and to bury their loved ones. All these activities are the center of the story we are about to tell, a
story written especially starting from material sources, the foundation of any archaeological research
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