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Le comportement sportif de l'homme jumeau
No full textGedda Luigi, De Panfilis Carlo. Le comportement sportif de l'homme jumeau. In: Bulletin de psychologie, tome 40 n°381, 1987. Psychologie de l'enfant. pp. 761-766
Etica pubblica e Bioetica del fine vita: riflessioni su un possibile confronto
No full textPublic Ethics deals with the normative justification of public institutions’ decisions and professional ethics. These meanings of public ethics can be compared and an incisive example concerns cure and care and the role of health care professionals. Issues such as the distribution of rights and resources or the development of a cost effective health care system are compared with care and doctor-patient relationship - that are traditional topics of applied ethics and a private space. A broad definition of bioethics has public implications. The end of life issues are significant for the attempt to outline a reflection on bioethics and public ethics. Dying, death and the physician-patient relationship require a theoretical analysis of their meaning and role in a public space conditioned by techno-scientific innovations. Dying and death are not just a private issue, they have a big impact on a set of social, political economic and legal matters
New insights into the immune pathway leading to progression of HIV infection
No full textAlthough a major problem of immune system during HIV infection is thought to be related to infection of key immunocompetent cells such as CD4+ lymphocytes and phagocyte, the strong immune dysfunction paralleling the development of HIV infection mainly concerns also apparent discrepancies regarding the roles played by CD8+ T lymphocytes. Insights over this important problem were recently gained by single cell analysis of different CD8+ subpopulations, both in progressive evolutionary stages of the infection and by longitudinal studies. It was possible, in such a way, to envisage the following immune pathways leading to progression of HIV infection. In early stages a protective, ′′non-cytotoxic′′ response presumably prevails, sustained by the CD8+ CD28+ subpopulation, which is able both to control HIV replication within CD4+ infected cells and to avoid possible dangerous attacks by cytotoxic cells. In late stages cytolytic responses progressively prevail, possibly mediated by CD8+ CD28+ subpopulation and amplified by the CB8+ subpopulation releasing IFNγ, against not only CD4+ infected cells, but also non-infected cells. Thus a pathway mediated by action of different CD8+ subpopulations may contribute to explain the development of HIV infection
Il ruolo dei monociti e dei radicali ossigeno nella patogenesi della sclerodermia sistemica
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