1,721,184 research outputs found
Nuovi indicatori molecolari per la prevenzione della patologia tumorale e degenerativa: la metilazione anomala del DNA
No full textEnvironmental monitoring of volatile organic compounds and metallic elements in two analysis laboratories
No full textEnvironmental monitoring of volatile organic compounds (VOCs) in analytical chemistry laboratories is somewhat tricky because exposure levels are highly variable and the number of toxic compounds, often used in combination, may be very high. This study was designed to evaluate airborne levels of VOCs and metallic elements associated to inhalable dusts in two Italian labs. The airborne levels of VOCs and elements fell well below the occupational exposure limit values recorded in the Italian law (D.lgs. 81/2008, Allegato XXXVIII) and the TLV-TWA from the list of American Conference of Governmental Industrial Hygienists. The determination of measurable levels of toxic and potentially carcinogenic compounds in office rooms may be of interest for personnel not specifically engaged to handle chemicals
[New perspectives in biomonitoring of metallic elements: the example of hexavalent chromium]
No full textPlating industry is an important productive sector in all the national territory, because of its contribution to a high number of industrial products and crafts. In the chrome plating sector there is a specific chemical risk due to the exposure to compounds containing hexavalent Chromium [Cr(VI)]. Exhaled breath condensate (EBC) has been used to study both acute and long term exposure to Cr(VI) in chrome plating workers. Cr-EBC correlates with specific oxidative stress biomarkers. Moreover, both total Cr and its hexavalent fraction can be measured in EBC, which therefore is a promising biological fluid to assess the absorbed dose at the target organ level, the pulmonary reduction kinetics of Cr(VI) and in general its local pneumotoxic effects. EBC collection and analysis could give additional information to the traditional measures performed during biomonitoring
Nuove prospettive nel monitoraggio biologico degli elementi metallici: l'esempio del cromo esavalente
No full textL’industria galvanica è un settore importante su tutto il territorio nazionale, poiché i processi che la caratterizzano riguardano un gran numero di fabbricazioni industriali ed artigianali. Nella cromatura galvanica esiste un rischio chimico specifico dovuto all’esposizione a composti contenenti Cromo esavalente [Cr(VI)]. Il condensato dell’aria espirata (CAE) è stato usato per studiare l’esposizione acuta e a lungo termine a Cr(VI) in lavoratori addetti alla cromatura a spessore. Cr-CAE correla con specifici
biomarcatori di stress ossidativo ed è possibile misurarne
anche la frazione non ancora ridotta a Cr(III). Il CAE è quindi un fluido biologico promettente per il monitoraggio della dose assorbita a livello dell’organo bersaglio, della cinetica di riduzione polmonare di Cr(VI) e più in generale dei suoi effetti locali pneumotossici nelle lavorazioni galvaniche, con la possibilità di affiancare la sua raccolta e la sua analisi alle misure tradizionalmente fatte durante il monitoraggio biologico
The chemical and carcinogenic risk in the steel industry
No full textThe sector of the steel industry, in the complex of his productive components, coking, steelworks, foundries, constitute a meaningful part of the national economy. The principal health risk factors are correlated to physical agents like noise and thermal stress and in particular to the presence of chemical agents like inhalable and respirable dusts, crystalline silica, synthetic mineral fibers, metals, vapors of more or less complex organic substances (benzene, polycyclic aromatic hydrocarbons, polychlorinated dibenzo dioxins, polychlorinated dibenzofurans, polychlorinated biphenils, etc.), gases (hydrogen sulfide, carbon monosside, nitrogen oxides. The paper introduces a synthesis of the productive plants, of the dangerous chemical agents, carcinogens and mutagenic to them correlated and potentially present in the sector
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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