1,721,038 research outputs found
I disturbi del comportamento alimentare: aspetti eziopatogenetici clinici e terapeutici
No full textAnorexia nervosa (AN) and bulimia nervosa (BN) are characterised by pathological concerns about body weight (BW) and shape, which usually result in severe food restriction with BW loss in AN and binge-purging behaviours without weight loss in BN. The Diagnostic and Statistical Manual for Mental Disorders Test Revision (DSM-IV TR) includes in the category of eating disorders (EDs) also eating disorders not otherwise specified (EDNOS). EDNOS are represented by partial syndromes not fulfilling all the DSM-IV TR criteria for AN or BN, and by binge-eating disorder (BED), characterised by binge eating without purging or restrictive behaviours, which results in a dramatic BW increase. AN and BN are more prevalent in females than in males, and affect especially adolescents in the age range from 12 to 25 years. The etiopathogenesis of EDs is not known; it is widely believed that both biological, psychological and psychosocial factors contribute to their genesis and/or their maintenance. Among the biological factors, substances involved in the regulation of eating behaviour and energy homeostasis are thought to play a major role, as suggested by both genetic and biochemical studies. From a clinical point of view, AN may lead to severe medical complications, which are threatening for the patient's life; BN is rarely a life frightening condition; in the BED medical complications are similar to those of obesity. Both AN and BN have a high incidence of psychiatric comorbidity, especially affective and anxiety disorders and personality disorders. The treatment of these syndromes requires multiple interventions, which include drugs, psychotherapies, nutritional counselling, psychoeducation and treatment of medical complications. At present, no effective prevention is available
Regolatori centrali e periferici di fame e sazietà nei disturbi del comportamento alimentare
No full text
Adrenoceptors modulate depressor responses of endothelin-1 into the superior colliculus of rats
No full textThe cDNA 385C to A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) is associated with overweight/obesity but not with binge eating disorder in overweight/obese women.
No full textEndocannabinoids are involved in the modulation of eating behavior; hence, alterations of this system may play a role in obesity. Recently, a single nucleotide polymorphism (cDNA 385C to A) of the gene coding for fatty acid amide hydrolase (FAAH), the major degrading enzyme of endocannabinoids, has been found to be associated with obesity. However, the possibility that the FAAH gene cDNA 385C to A single nucleotide polymorphism (SNP) is associated to binge eating disorder (BED), a condition that frequently occurs in obese individuals, has not been investigated. In order to address this issue, we assessed the distribution of the cDNA 385C to A SNP in 115 overweight/obese subjects with BED, 74 non-BED patients with obesity and 110 normal weight healthy controls. As compared to healthy controls, the whole group of overweight/obese BED and non-BED patients had a significantly higher frequency of the CA genotype and the A allele of the FAAH gene cDNA 385C to A SNP. Moreover, the SNP resulted significantly correlated to the presence of overweight/obesity (F(2, 296)=3.58, P=0.02), but not to the occurrence of BED (F(2, 296)=0.98; P=0.3). The present study confirms previously published significant over-representations of the FAAH 385 A allele in overweight/obese subjects and presents new data in BED patients that the 385 mutation is not significantly associated with BED-related obesity
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Ritmo nictemerale di alimentazione di Syngnathus taenionotus e S. abaster (Osteichthyes, Syngnathidae) in una laguna del delta del Po.
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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