3,082 research outputs found
Response to Foulkes and De Gruttola
No full textThis note is the authors' response to the Reader's Reaction provided by Foulkes and De Gruttola as published in Statistical Applications in Genetics and Molecular Biology
Enterocutaneous fistula treatment: case report and review of the literature
No full textThe aim of this work is to evaluate the treatment strategies for a common major surgery complication like the enterocutaneous fistula (ECFs). Since there is not any standard treatment for this common disease and since new therapies, like NPWT and fibrin sealants, have come up a review of all their indications seemed useful. We also present two clinical cases treated in this way
Too late to tell: Changing reactions to social norm transgressions through middle childhood
No full textCommunication describes how reactions to social norm transgressions change through middle childhoo
Charm-quark fragmentation fractions and productioncross section at midrapidity in pp collisions at the LHC
No full textCharmonium photoproduction in ultra-peripheral p-Pb and Pb-Pb collisions with ALICE at the LHC
No full textThe photoproduction of vector mesons in Ultra-Peripheral Collisions (UPC) is a powerful tool to probe the nuclear gluon distribution (Pb-Pb collisions) and the gluon structure function in the proton (p-Pb collisions). The first measurements of coherent photoproduced J/ψ and ψ(2S) in Pb-Pb collisions at √sNN = 2.76 TeV, performed with the ALICE detector, are described and compared to STARLIGHT and QCD based models, in order to investigate nuclear gluon shadowing. The results of the measurement of exclusive J/ψ photoproduction off protons in p-Pb collisions at √sNN = 5.02 TeV are also presented
Physics of ultra-peripheral collisions with ALICE at the LHC
No full textThe photoproduction of vector mesons in ultra-peripheral colli- sions (UPC) is a powerful tool to probe the nuclear gluon distribution (Pb-Pb collisions) and the gluon structure function in the proton (p-Pb collisions). The first measurements of coherent photoproduced J /ψ and ψ (2S) in Pb-Pb collisions at √ s NN =2 . 76 TeV, performed with the ALICE detector, are reported and compared to STARLIGHT and QCD based models, in order to investigate nuclear gluon shad- owing. The first results of the measurement of exclusive J /ψ photoproduction off protons in p-Pb collisions at √ s NN =5 . 02 TeV performed by the ALICE Collabora- tion are also mentione
Systemic Administration of Sphingosine-1-phosphate Increases Bronchial Hyper-Responsiveness in the Mouse
No full textSystemic administration of sphingosine-1-phosphate increases bronchial hyperresponsiveness in the mouse.
No full textSphingosine-1-phosphate (S1P) is a bioactive sphingolipid that plays important roles in allergic responses, including asthma. S1P acts on many cell types, such as mast cells, the airway epithelium, airway smooth muscle, and many immune cells. In this study we have evaluated whether a systemic administration of S1P to Balb/c mice modifies airway reactivity. Our data show that S1P (0.1-10 ng) given subcutaneously to Balb/c mice causes a specific and dose-dependent increase in cholinergic reactivity of bronchial tissues in vitro. This effect is (1) dose dependent, with a maximal effect of the dose of 10 ng of S1P; and (2) time dependent, reaching a maximal effect 21 days after S1P administration. Similarly, in the whole lung assay there is a dose- and time-dependent increase in lung resistance. Lungs isolated from S1P-treated mice displayed an increase in mast cell number. Furthermore, there is an increase of IL-4, IL-13, and IL-17 production. In conclusion, our data demonstrate that S1P signaling is involved in the complex pathway underlying airway hyperresponsiveness
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