36 research outputs found
AB0027 Screening for antibody reactivity in early axial spondyloarthritis identifies novel antigenic targets
No full textGeographisch Handtbuch; In welchem die gelegenheit der vornembsten Lantschafften des gantzen Erdtbodems in zwej vnd achtzig in kupffer geschnittenen Taffeln furgebildt ; Mit beygefügter notwendiger Beschreibung vnd auslegung derselben: also das jedes Landes art, natur, gelegenheit, sitten, völcker, fruchtbarkeit, handtirung sampt andere zu wissen nutzliche sachen, schrifftlich vnd augenscheinlich nach notturfft daraus mögen erlernet werden
No full textIn mehreren Varianten gedruckt. Variante 1: am Anfang [4] Blatt, enthaltend nach dem Titelblatt die Widmung Johann Bussemachers an Hieronymus von Krebs, die Vorrede Matthias Quads und das Register. – Variante 2: am Anfang [2] Blatt, enthaltend nach dem Titelblatt nur das Register.Kupfert., 82 Kt. (Kupferst.), 2 Ill.Vorlageform des Erscheinungsvermerks: COLN AM REIN || Bey Iohan Buxemacher Kunst/|| drucker vff S.Maximini strass daselbst.|| M D C.||Titeleinfassung, Ill. (Holzschn.), Ill. (Kupferst.
Antibodies of the immunoglobulin a isotype to novel antigens in early axial spondyloarthritis
No full textIntroductionThere is an unmet need for biomarkers to identify patients with axial spondyloarthritis (axSpA). Increasing evidence suggest the presence of autoantibodies in a subset of axSpA patients. The aim of this study was to identify novel IgA antibodies in early axSpA patients and to determine their diagnostic potential in combination with previously determined IgG antibodies against UH (Hasselt University)-axSpA-IgG antigens. MethodsAn axSpA cDNA phage display library constructed from axSpA hip synovium, was used to screen for novel IgA antibodies in plasma from early axSpA patients. The presence of these antibodies against novel UH-axSpA-IgA antigens was determined in two independent axSpA cohorts, in healthy controls and in patients with chronic low back pain. ResultsWe identified antibodies to 7 novel UH-axSpA-IgA antigens, of which 6 correspond to non-physiological peptides and 1 to the human histone deacetylase 3 (HDAC3) protein. IgA antibodies against 2 of these 7 novel UH-axSpA-IgA antigens and IgG antibodies against 2 of the previously identified antigens were significantly more present in early axSpA patients from the UH cohort (18/70, 25.7%) and the (Bio)SPAR cohort (26/164, 15.9%), compared to controls with chronic low back pain (2/66, 3%). Antibodies to this panel of 4 antigens were present in 21.1% (30/142) of patients with early axSpA from the UH and (Bio)SPAR cohorts. The positive likelihood ratio for confirming early axSpA using antibodies to these 4 UH-axSpA antigens was 7.0. So far, no clinical correlation between the novel identified IgA antibodies and inflammatory bowel disease could be identified. DiscussionIn conclusion, screening an axSpA cDNA phage display library for IgA reactivity resulted in the identification of 7 novel UH-axSpA-IgA antigens, of which 2 show promising biomarker potential for the diagnosis of a subset of axSpA patients, in combination with previously identified UH-axSpA-IgG antigens
The prevalence of vertebral fractures in spondyloarthritis: relation to disease characteristics, bone mineral density, syndesmophytes and history of back pain and trauma
No full textIntroduction: An increased risk of vertebral fracture (VF) is one of the extra-articular manifestations of spondyloarthropathy (SpA). The prevalence of moderate to severe VFs visualized by radiography (Rx) in patients with SpA in daily practice is unknown until imaging of the full spine is available, as most VFs do not present with clinical signs and symptoms of an acute fracture. Methods: We evaluated the prevalence of VFs (>25 % loss in height) on available Rx and dual-energy X-ray absorptiometry (DXA) images in 390 consecutive patients with SpA in daily practice. We assessed their association with disease characteristics, bone mineral density, the modified Stoke Ankylosing Spondylitis Spinal Score, and history of trauma. Results: Forty-six patients (11.8 %) had Rx VF (56.4 % men, 93.5 % in the thoracic spine), and 44.5 % had multiple VFs. Compared with patients without VF, patients with VF were older (52.2 vs. 47.3 years, p <0.01; range 25-84 years), had lower femoral neck T-scores (-1.1 vs. -0.7; p <0.05), and had a marginally higher modified Stoke Ankylosing Spondylitis Spinal Score (11.7 vs. 7.0; p = 0.06). Among patients with VFs, 15.2 % had a history of trauma with acute back pain (p <0.001 vs. no VF). The reliability of DXA for diagnosing radiographic VFs was high (kappa 0.90). Conclusions: Moderate to severe VFs are found in more than 10 % of patients with SpA before the age of 40 years in 5 % of women and 9 % in men. Most VFs are located in the thoracic region, are related to low femoral neck bonemineral density and to stiffening of the spine, and are only rarely related to trauma history. DXA is a useful alternative for diagnosing VFs
Payment network scale economies, SEPA, and cash replacement
No full textThe goal of SEPA (Single Euro Payments Area) is to facilitate the emergence of a competitive, intra-European market by making cross-border payments as easy as domestic transactions. With crossborder inter-operability for electronic payments, card transactions will increasingly replace cash and checks for all types of payments. Using different methods, the authors estimate card and other payment network scale economies for Europe. These indicate substantial cost efficiency gains if processing is consolidated across borders rather than "piggybacked" onto existing national operations. Cost reductions likely to induce greater replacement of small value cash transactions are also illustrated.
Privatization of Mexico's public enterprises and the restructuring of the private sector
No full textPublic enterprises, Government enterprises, Privatization, Private sector, Mexico
Metas de inflação: uma análise comparativa entre mercados emergentes da América Latina
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico. Programa de Pós-graduação em Economia
Efficiency and costs of payments: some new evidence from Finland
No full textThis paper deals with optimal payment systems. The issue boils down to how large are the costs of different payment media, which can be interpreted as a question of the efficiency of the means of payment. However, there are other qualifications related to the choice of payment media. Here, at least three issues can be distinguished. First is the question of optimal payment medium for each individual payment (size, location, EFTPOS etc.). This choice is not independent of the individual characteristics of the payer and payee. Secondly, there is the question of cost effectiveness of payments for different institutions and sectors. The final issue concerns the social optimum for each payment medium. These issues have been particularly controversial in the case of cash, which is still the dominant payment medium in most euro countries. Part of the controversy arises from the fact that the costs and benefits of different payment media affect different market participants in quite different ways, so that a possible social optimum might not correspond eg to the optima for different firms. The paper contains a short review of calculation methods and empirical results for a sample of countries. It also provides new evidence from Finland, which is to an extent one of the front-runners in payment technology and institutional design in payment systems. This shows up in relatively low overall costs of payments. Our estimate of total costs of payment media is 0.3 per cent of GDP, which is very low by international standards.payment media; cash; payment systems; costs of payments
Acta Antiqua
No full text1968 / 1-4. sz. 1
E. CH. WELSKOPF: Religion als Geschichte
V. I. GEORGIEV: Das ie. Wort für "Träne"
G. KOMORÓCZY: Zum sumerischen Epos "Enmerkar und der Herr von Aratta"
A. DOBROVITS: Sur la structure stylistique de l'Enseignement de Ptahhotep
L. KÁKOSY: Zu einer Etymologie von Philä: "Insel der Zeit"
A. MOZSOLICS: Bronzezeitliche Edelmetallwaffen
J. HARMATTA: Zu den kleinasiatischen Beziehungen der griechischen Mythologie
P. SZALMÁSI: K izucseniju kavkazszkih variantov mifa o Prometee
L. STOIANOVICI: La notion de "Hybris" dans l'Iliade
ZS. RITOÓK: The Epithets for Minstrels in the Odyssey
J. ZSILKA: Bemerkungen über die Bedeutung homerischer Wörter
D. HEGYI: Der Kult des Dionysos Aisymnetes in Patrae
I. LENGYEL: Früheisenzeitliche inschriftliche Denkmäler
J. GY. SZILÁGYI: L'"oenochoé de Mitrovica"
I. M. TRONSZKIJ: Zametki k Szapfo I. (L.-P.)
R. FALUS: Analyse der Fragmente 1. und 2. von Epicharm
J. WOHLBERG: The Palace-Hero Equation in Euripides
S. SZÁDECZKY-KARDOSS: Ein Kapitel aus dem Nachleben des Mimnermos: Philetas und Mimnermos
K. SZABÓ: Ein Philetas-Fragment in der Tradition des Streites mit Mimnermos
M. SZABÓ: Zur Frage des keltischen Fundes von Isthmia
P. OLIVA: Die Auslandspolitik Kleomenes' III
L. CASTIGLIONE: Inverted Footprints Again
D. M. PIPPIDI: Xenika dionüsia a Callatis
E. MAYER: Das Sauprodigium and sein religionsgeschichtlicher Hintergrund
E. FERENCZY: Zur Vorgeschichte des zweiten römösch-punischen Vertrags
M. B. RÉVÉSZ: Si duo dicunt idem, non est idem
A. MICHEL: Cicéron et les Paradoxes stoiciens 225
E. MARÓTI: A Recently Found Versified Oracle Against the Pirates
I. HAHN: Zur Interpretation der Vulcatius-Prophetie
GY. ÜRÖGDY: Der Fiscus: ein Pfeiler der augusteischen Politik
K. AKBAR KHAN: Sea-Symbolism in Propertius, 1,11
Z. KÁDÁR: Filia ton zoon
I. BORZSÁK: Ovidianum
F. NAGY: The Contrast Signs of an Antique Topos
L. L. HAMMERICH: Die Germania des Tacitus
ST. MROZEK: Zur Frage der tutela in römischen Inschriften
T. NAGY: Die Auszeichnungen des P. Besius Bituinianus und das Problem der dona militaria zu Trajans Zeitalter
D. GABLER: Scratched Insciptions on Terra Sigillata in Pannonia
SZ. G. EFERIDZS: Plutarh o peremenah doktrinü
J. FITZ: M. Campanius Marcellus
B. GEROV: Die Krisis in den Ostbalkanländern während der Alleinregierung des Marcus Aurelius
R. MERKELBACH: Ein korrupter Satz im Brief Marc Aurels über das Regenwunder im Feldzug gegen die Quaden
I. G. NAGY: Bemerkungen zur Deutung der Stelle SHA Vita Marci 14
A. MÓCSY: Latrones Dardaniae
M. FÜZES: Über die Fruchtdarstellungen des Füllhorndeckels von Savaria
K. VISKY: Spuren der Wirtschaftskrise des III. Jahrhunderts in den römischen Rechtsquellen
K. SÁGI: Darstellung des altchristlichen Kreuzes auf einem römischen Ziegel
F. FÜLEP: Early Christian Gold Glasses in the Hungarian National Museum
L. VÁRADY: Stilicho proditor arcani imperii 415
V. A. LIVSHITS: The Khwarezmian Calendar and the Eras of Ancient Chorasmia
CS. TÖTTÖSY: The Sukasaptati Variants and the Jaina Authorship
GY. MORAVCSIK: Buzantion eis to katoptrov ton donomaton tou
Á. R. SZALAY: Die literarische Tätigkeit von Imre Trencsényi-Waldapfe
