552 research outputs found

    Mayy Ziyada (1883-1941) tra femminismo e nazionalismo

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    the arab Nahḍa, a cultural Renaissance that spanned the period from late 19th to early 20th century, witnessed the spring of new issues and tendencies. in egypt, women intellectuals claimed more space in the public debate, while supporting the nationalist movements which ultimately led to the independence of the country. among them, the eclectic author Mayy Ziyāda (1883-1941) played a pivotal role in the elaboration of nationalistic and gender-related issues. this study investigates Ziyāda’s writings about women’s condition, showing how she was actually more focused on the liberal political discourse rather than feminist theories and practices. it also aims at demostrating how Ziyāda, who was crucial in defining a canon of women’s culture of her time, did not embrace it completel

    Beneficial Effects of Physical Sport Activity in Multiple Sclerosis Patients

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    Multiple sclerosis (MS) is the most common demyelinating disabling disease of the central nervous system in young adults. In the last years, a great amount of studies have been done in order to understand the possible beneficial effects of physical activity and sport in this disease. In this paper a focus on the effects and safety of physical activity and sport in patients affected by MS has been done

    Layla al-Ahyaliyya, poetessa e personaggio tra esemplarità ed eversione

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    Laylā al-Aḫyaliyya (d. 84/704 ca.) is one of the most prominent Umayyad women poets. She gained fame not only as an author of elegies, satires and encomiums, but also as a protagonist of a romantic saga with the poet Tawba ibn al-Ḥumayyir, and witty verbal exchanges with authorities and poets. In modern times, her unconventional figure appeared in Zaynab Fawwāz’s biographical dictionary of famous women al-Durr al-Manūr (1894). This study aims to sketch out the figure of Laylā in ancient sources and to analyse how Fawwāz reused this information to outline her as a character between exemplarity and subversion, thus making Laylā part of her project of building an Arabo-Islamic feminine heritage to inspire the women of her age

    Figure femminili classiche nella poesia di Fadwà Tuqan, tra conformità e trasgressione

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    Several trends and influences combine in the poetry of the Palestinian author Fadwà Tuqan (1917-2003). Her first collections show how she adheres to the trends of the classical Arabic tradition, both in forms and subjects; the author then gradually commits herself towards new structures, and political themes. This essay focuses on the presence and persistence of issues related to classical literature in Fadwà Tuqan’s poetry, both in her early works and, reelaborated in a symbolic and sometimes provocative way, in her following production

    Possible relationship between Al/Ferritin complex and Alzheimer's Disesae

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    Abstract Objectives Ferritin is the main iron-storage protein capable of containing thousands of iron atoms. However, ferritin can bind in vitro other atoms such as aluminum and it has been shown that also in vivo atoms other than iron, as aluminum and zinc, are present in large amounts in ferritin. Since aluminum appears to be involved in the development of Alzheimer's disease, in the present study the specific content of aluminum in ferritin of Alzheimer's patients was analyzed and compared with other control groups. Design and methods The content of Fe, Al and Zn of blood ferritin was measured by mass spectrometry in patients with Alzheimer's disease and compared with other clinical and control groups. Results The results obtained confirm the hypothesis of a functional role of ferritin as a regulatory protein of toxic metals and clearly indicate that ferritin from Alzheimer's patients has a content of aluminum higher than that of controls. Conclusions The specific aluminum content of ferritin seems to be related to different disease stages of Alzheimer's disease. This result confirms the hypothesis of aluminum as a possible factor inducing the Alzheimer's disease and opens the ways to possible new diagnostic tests

    Expression in Escherichia coli of thermostable elongation factor I alpha from the archaeon Sulfolobus solfataricus

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    The elongation factor 1 alpha from the archaeon Sulfolobus solfataricus (SsEF-1 alpha) was expressed in Escherichia coli and purified. The SsEF-1 alpha gene was amplified by PCR and cloned in the Ndel site of the pT7-7 expression vector, under the control of the promoter of T7 RNA polymerase. Upon induction with isopropyl beta-D-thiogalactopyranoside, the recombinant SsEF-1 alpha (recSsEF-1 alpha) was purified from the E. coli S-100 extract by a two-step procedure. From 1 litre of cell culture, about 2 mg of purified recSsEF-1 alpha was obtained, The N-terminal sequence of the first 30 amino acid residues of recSsEF-1 alpha was identical with that translated from the nucleotide sequence of the corresponding gene, except for the initial residue, which in recSsEF-1 alpha was Ser instead of Met. The M(r) of recSsEF-1 alpha (determined by electrospray MS) was almost coincident with that of the naturally occurring SsEF-1 alpha (SsEF-1 alpha). The thermal-inactivation and thermophilicity profiles of SsEF-1 alpha and recSsEF-1 alpha were identical. Concerning the functional properties, recSsEF-1 alpha was able to support poly(Phe) synthesis in vitro, to bind GDP and GTP and to elicit an NaCl-dependent GTPase activity [Masullo, De Vendittis and Bocchini (1994) J. Biol. Chem. 269, 20376-20379] with the same efficiency as that displayed by SsEF-1 alpha

    Oleanane type glycosides from Paronychia anatolica subsp. balansae

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    Four new oleanane-type triterpene glycosides were isolated from the methanol extract of the roots of Paronychia anatolica subsp. balansae along with three known oleanane-type triterpene glycosides. Structures of the new compounds were established as 3-O-beta-D-glucuronopyranosyl-28-O-[alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-quinovopyranoside] zahnic acid, 3-O-beta-D-glucuronopyranosyl-28-O-[beta-D-xylopyranosyl-(1 -> 4)-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-quinovopyranoside] zahnic acid, 3-O-beta-D-glucuronopyranosyl-28-O-[alpha-L-arabinofuranosyl(1 -> 2)-beta-D-quinovopyranoside] zahnic acid, 28-O-beta-D-rhamnopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranosyl]-medicagenic acid, by using 1D and 2D-NMR techniques and mass spectrometry. The cytotoxic activity of the isolated compounds was evaluated against a small panel of cancer cell lines including human breast cancer (MCF-7), human lung adenocarcinoma (A549) and human leukemia (U937) cell lines. (C) 2013 Elsevier B.V. All rights reserved.Ege University Research FoundationEge University [2013 Fen 042]The authors are grateful to Ege University Research Foundation (2013 Fen 042) for the financial support and also to Assoc. Prof. Dr. Serdar G. SENOL for the identification of plant material

    Expression in Escherichia coli of thermostable elongation factor 1 alpha from the archaeon Sulfolobus solfataricus

    No full text
    The elongation factor 1 alpha from the archaeon Sulfolobus solfataricus (SsEF-1 alpha) was expressed in Escherichia coli and purified. The SsEF-1 alpha gene was amplified by PCR and cloned in the Ndel site of the pT7-7 expression vector, under the control of the promoter of T7 RNA polymerase. Upon induction with isopropyl beta-D-thiogalactopyranoside, the recombinant SsEF-1 alpha (recSsEF-1 alpha) was purified from the E. coli S-100 extract by a two-step procedure. From 1 litre of cell culture, about 2 mg of purified recSsEF-1 alpha was obtained. The N-terminal sequence of the first 30 amino acid residues of recSsEF-1 alpha was identical with that translated from the nucleotide sequence of the corresponding gene, except for the initial residue, which in recSsEF-1 alpha was Ser instead of Met. The M(r) of recSsEF-1 alpha (determined by electrospray MS) was almost coincident with that of the naturally occurring SsEF-1 alpha (SsEF-1 alpha). The thermal-inactivation and thermophilicity profiles of SsEF-1 alpha and recSsEF-1 alpha were identical. Concerning the functional properties, recSsEF-1 alpha was able to support poly(Phe) synthesis in vitro, to bind GDP and GTP and to elicit an NaCl-dependent GTPase activity [Masullo, De Vendittis and Bocchini (1994) J. Biol. Chem. 269, 20376-20379] with the same efficiency as that displayed by SsEF-1 alpha

    Riflessioni sull'autorialità: il caso del poeta Ibn Zurayq al-Baghdadi

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    Several sources from XI to XVI cent. report a fine ‘ayniyya, giving versions of it which differ in length, varying from two to over forty verses. At first this poem had various attributions, or had no given author at all. It was later attributed to Abū l-Ḥasan ‘Alī ibn Zurayq al Baġdādī, a XI cent. poet from Iraq, who apparently only wrote this qaṣīda and had a troubled life with a tragic end. The little information available about him is inferable from the poem itself and the related story conveyed by some of the compilers. This paper aims to reconstruct the path of the attribution of the authorship of the ‘ayniyya. The analysis is based on the four authorial functions given by Michel Foucault and aims at balancing actual information and the legend. The main categories of the theory of cooperative reading by Eco are also used, in order to distinguish authorial, textual and critical intentions
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