1,430 research outputs found

    Author Peter FitzSimons speaking at the National Library of Australia, Canberra, 13 November 2012 /

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    Title from acquisitions documentation.; Part of the collection: Portraits of author Peter FitzSimons speaking at the National Library of Australia, Canberra, 13 November 2012.; Acquired in digital format; access copy available online.; Mode of access: Online.; Photographed by a staff member of the National Library of Australia

    Fitzsimons, D W, WX1043

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/385357Surname: FITZSIMONS. Given Name(s) or Initials: D W. Military Service Number or Last Known Location: WX1043. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 4212.234967 Item: [2016.0049.17650] "Fitzsimons, D W, WX1043

    Front Matter of Combating Violence & Abuse of People with Disabilities: A Call to Action

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    Complete Digitized Text of the Front Matter (Contents, About the Author, Contributors, Forward by Dick Sobsey, Preface, and Acknowledgments) of the book Combating Violence & Abuse of People with Disabilities: A Call to Action by Nancy M. Fitzsimons.https://cornerstone.lib.mnsu.edu/books-fitzsimons-combating-violence/1001/thumbnail.jp

    le réseau ramau fête ses 20 ans | parution du cahier n° 10

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    Depuis vingt ans, le réseau Ramau mobilise chercheurs et professionnels autour de la fabrication de la ville. A PAVE, Patrice Godier est l'un de ses membres fondateurs, rejoint depuis par Laura Brown, Olivier Chadoin, Aurélie Couture et J. Kent Fitzsimons. RAMAU a pour ambition de mettre les résultats de la recherche à disposition de tous ceux qui s’intéressent aux activités et métiers de l’architecture et de l’urbanisme, et d’ouvrir les débats aux savoirs et aux modèles de la conception et d..

    The Brand Dislike Construct: Scale Development and Application to Actual Brands

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    The paper aims to describe the concept of brand dislike and presents the results of implementing a brand dislike scale. First of all we analyzed brand dislike on a hypothetical brand and then we applied the measurement scale to actual brands. Data were collected in 2005 in Italy, and the sample was formed from ordinary consumers. From a theoretical/methodological point of view, this research fills a gap in brand attitude research literature: provided that negative attitudes can-not be reduced to the opposite of positive attitudes, they have to be measured with specific tools. At the operational level, this research shows interesting opportunities in terms of brand analysis and managemen

    The effects of yoga compared to active and inactive controls on physical function and health related quality of life in older adults:Systematic review and meta-analysis of randomised controlled trials

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    Background: Yoga has been recommended as a muscle strengthening and balance activity in national and global physical activity guidelines. However, the evidence base establishing the effectiveness of yoga in improving physical function and health related quality of life (HRQoL) in an older adult population not recruited on the basis of any specific disease or condition, has not been systematically reviewed. The objective of this study was to synthesise existing evidence on the effects of yoga on physical function and HRQoL in older adults not characterised by any specific clinical condition. Methods: The following databases were systematically searched in September 2017: MEDLINE, PsycInfo, CINAHL Plus, Scopus, Web of Science, Cochrane Library, EMBASE, SPORTDiscus, AMED and ProQuest Dissertations & Theses Global. Study inclusion criteria: Older adult participants with mean age of 60 years and above, not recruited on the basis of any specific disease or condition; yoga intervention compared with inactive controls (example: wait-list control, education booklets) or active controls (example: walking, chair aerobics); physical function and HRQoL outcomes; and randomised/cluster randomised controlled trials published in English. A vote counting analysis and meta-analysis with standardized effect sizes (Hedges’ g) computed using random effects models were conducted. Results: A total of 27 records from 22 RCTs were included (17 RCTs assessed physical function and 20 assessed HRQoL). The meta-analysis revealed significant effects (5% level of significance) favouring the yoga group for the following physical function outcomes compared with inactive controls: balance (effect size (ES) = 0.7), lower body flexibility (ES = 0.5), lower limb strength (ES = 0.45); compared with active controls: lower limb strength (ES = 0.49), lower body flexibility (ES = 0.28). For HRQoL, significant effects favouring yoga were found compared to inactive controls for: depression (ES = 0.64), perceived mental health (ES = 0.6), perceived physical health (ES = 0.61), sleep quality (ES = 0.65), and vitality (ES = 0.31); compared to active controls: depression (ES = 0.54). Conclusion: This review is the first to compare the effects of yoga with active and inactive controls in older adults not characterised by a specific clinical condition. Results indicate that yoga interventions improve multiple physical function and HRQoL outcomes in this population compared to both control conditions. This study provides robust evidence for promoting yoga in physical activity guidelines for older adults as a multimodal activity that improves aspects of fitness like strength, balance and flexibility, as well as mental wellbeing

    Lost in translation: The power of language

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    This paper brings together ideas about culture, difference and the importance of translation and interpretation in educational contexts. A key component of this paper is the promotion of curriculum based on a dialogical framework.The paper developed an argument of the impossibility of perfect translation, and points towards linguistic hospitality as the ethical dimension to the inadequate representation of the ‘other’. It highlights the complex role of teacher as translator – an activity that is relational and creative - and the child in translation as a process of metamorphosis rather than reproduction. We were asked to submit this paper to a special Special Issue on Power and Language for Education Philosophy and Theory after presenting a paper on a similar theme at the Philosophy of Education Conference, Brisbane, December, 2008. This special issue is to be re-published in book form in 2012. Educational Philosophy and Theory has an ERA research journal ranking of A+ and a Q score of 19.93. This paper brings together ideas about culture, difference and the importance of translation and interpretation in educational contexts. A key component of this paper is the promotion of curriculum based on a dialogical framework.The paper developed an argument of the impossibility of perfect translation, and points towards linguistic hospitality as the ethical dimension to the inadequate representation of the ‘other’. It highlights the complex role of teacher as translator – an activity that is relational and creative - and the child in translation as a process of metamorphosis rather than reproduction. We were asked to submit this paper to a special Special Issue on Power and Language for Education Philosophy and Theory after presenting a paper on a similar theme at the Philosophy of Education Conference, Brisbane, December, 2008. This special issue is to be re-published in book form in 2012. Educational Philosophy and Theory has an ERA research journal ranking of A+ and a Q score of 19.93. My contribution Each author contributed equally to the structure, organization, development and writing of the paper. Peter Fitzsimons contributed the writing on Nietszche, and I contributed the writing on linguistic hospitality. We worked equally on the theorizing of translation in regard to Foucault and Derrida. My specific contribution develops Ricoeurean concepts in particular the writing on linguistic hospitality. This concept promotes the importance of shared understandings, the role of metaphor in creating new understandings, and the critical role of readership in interpretation

    Suppressors of cytokine signalling (SOCS) 2 and 3 diametrically control macrophage polarisation

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    Suppressors of cytokine signalling (SOCS) 2 and 3 diametrically control macrophage polarisation S. Spence,* A. Fitzsimons,* C. Boyd,* J. Kessler,* D. Fitzgerald,* J. Elliott,* J. Ni Gabhann, S. Smith, A. Sica, E. Hams,§ S. P. Saunders,§ C. Jefferies, P. Fallon,§ D. Mcauley,* A. Kissenpfennig* & J. Johnston* *Queen’s University Belfast, Belfast, UK, Royal College of Surgeons in Ireland, Dubin, Ireland, Instituto Clinca Humanitas, Milan, Italy, §Trinity College Dublin, Dublin, Ireland M1 macrophages, induced by pro-inflammatory stimuli, and involved in the acute response. M2 macrophages are polarised by anti-inflammatory stimuli and mainly involved in healing. The Suppressors of cytokine signalling (SOCS) are important regulators of both LPS and cytokine responses but their role in macrophage polarisation is unknown. Myeloid restricted SOCS3 deletion (SOCS3LysMcre) resulted in profound resistance to endotoxic shock, whereas SOCS2)/) mice were highly susceptible. This was associated with striking bias towards M2-like macrophages in SOCS3LysMcre mice, whereas the M1-like population was enriched in SOCS2)/) mice. Through adoptive transfer experiments we show that these antipodal responses to endotoxic shock and to polymicrobial sepsis (caecal ligation puncture) were both transferable and entirely macrophage-dependent. Critically this dichotomous response was associated with enhanced T-reg recruitment by SOCS3)/) cells, yet in the presence of SOCS2)/) macrophages, Foxp3+ T cells were completely absent at the inflammatory site. The altered polarisation coincided with enhanced IFNc- induced STAT1 in SOCS2)/) macrophages and enhanced IL-4/ IL-13 induced STAT6 phosphorylation in SOCS3)/) cells corresponding to altered binding to traditional gene markers of M1 and M2 macrophages (iNOS, TNFa, ARG-1 and CCL-17,). In the absence of SOCS2, macrophages seem unable to elicit an anti- inflammatory response even when stimulated with typical M2 stimulus (IL-4/IL-13, IL- 10), whilst the absence of SOCS3 prevents a pro-inflammatory response even in the presence of LPS/IFNc. Interestingly, the polarisation of macrophages in the absence of SOCS2 or SOCS3 seems fixed and irreversible. Therefore SOCS are essential controllers of macrophage polarisation and regulate the inflammatory response
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