695 research outputs found
Dataset for publication: 'Highly-Chirped Bragg Gratings for Integrated Silica Spectrometers'
No full textRaw data used to create figures as well as Aerobasic code used to create device.
Data supporting the publication:
Field, J, Berry, SA, Bannerman, R, Smith, D, Gawith, C, Smith, PGR & Gates, J 2020, 'Highly-chirped Bragg gratings for integrated silica spectrometers' Optics Express, vol. 28, no. 14, pp. 21247-21259. DOI: 10.1364/OE.389211</span
Bannerman D.-A. — Larger birds of West Africa. London, Penguin Books. African series, WA 10, 1958
No full textBourlière François. Bannerman D.-A. — Larger birds of West Africa. London, Penguin Books. African series, WA 10, 1958. In: La Terre et La Vie, Revue d'Histoire naturelle, tome 12, n°3, 1958. p. 232
Bannerman, D. A. — The Birds of the British Isles. Volume IX. Edinburgh and London, Oliver and Boyd, 1960
No full textBourlière François. Bannerman, D. A. — The Birds of the British Isles. Volume IX. Edinburgh and London, Oliver and Boyd, 1960. In: La Terre et La Vie, Revue d'Histoire naturelle, tome 15, n°2-3, 1961. p. 383
Bannerman D.-A. — The birds of the British Isles. Volume 7, Anatidae (Conclusion) Edinburgh and London, Oliver and Boyd, 1958
No full textBourlière François. Bannerman D.-A. — The birds of the British Isles. Volume 7, Anatidae (Conclusion) Edinburgh and London, Oliver and Boyd, 1958. In: La Terre et La Vie, Revue d'Histoire naturelle, tome 12, n°3, 1958. p. 232
Book review: The war prerogative: history, reform, and constitutional design by Rosara Joseph
No full text"The War Prerogative: History, Reform, and Constitutional Design." Rosara Joseph. Oxford University Press. September 2013. --- In this book, Rosara Joseph studies the evolution of the war prerogative in England from 1600-2012. The author traces the historical theory and practice of the war prerogative and proposes reform of the constitutional arrangements for its exercise. Meticulously-researched and written in a lively and engaging style, the book will interest scholars in international and constitutional law, political science, and modern history, writes Gordon Bannerman
Evaluation of assays for the measurement of bovine neutrophil reactive oxygen species
No full textDuring mastitis and other bacterial-mediated diseases of cattle, neutrophils play a critical role in the host innate immune response to infection. Neutrophils are among the earliest leukocytes recruited to the site of infection and contribute to host innate immune defenses through their ability to phagocytose and kill bacteria. The bactericidal activity of neutrophils is mediated, in part, through the generation of reactive oxygen species (ROS). Extracellular release of ROS can induce injury to host tissue as well, and aberrant release of ROS has been implicated in the pathogenesis of certain inflammatory-mediated diseases. Due to their essential role in bacterial clearance and implicated involvement in the pathogenesis of other diseases, there is much interest in the study of neutrophil-generated ROS. Several assays have been developed to measure ROS production, however, many of these have not been evaluated with bovine neutrophils. The objectives of the current study were to evaluate different assays capable of measuring bovine neutrophil ROS, and to compare the results of assays never previously tested with bovine neutrophils to those obtained from more well-established assays frequently used with these cells. Eight different assays were evaluated, including: luminol, isoluminol, and methyl cypridina luciferin analog (MCLA) chemiluminescence assays; Amplex Red, dihydroethidium (DHE), dichlorodihydrofluorescein diacetate (CM-H(2)DCFDA), and dihydrorhodamine 123 fluorescence assays; and the cytochrome c absorbance assay. The assays were evaluated in the context of their abilities to detect ROS produced in response to two agonists commonly used to induce neutrophil activation, phorbol 12-myristate, 13-acetate (PMA) and opsonized zymosan. Diphenyleneiodonium chloride, a NADPH oxidase inhibitor, was used to assess the specificity of the assays to detect ROS. The ability of these assays to discriminate between intra- and extracellular ROS and to specifically detect distinct ROS was evaluated using superoxide dismutase and catalase, which scavenge extracellular superoxide and hydrogen peroxide, respectively. With the exception of the DHE assay, all assays detected bovine neutrophil ROS generation elicited by PMA and zymosan. PMA, but not zymosan, was able to stimulate neutrophil generation of ROS at levels that were detectable with DHE. The MCLA chemiluminescence assay was the only assay that detected ROS produced in response to each of the lowest concentrations of PMA and zymosan tested. To our knowledge, this is the first study to evaluate DHE-, MCLA-, Amplex Red-, and isoluminol-based assays for the measurement of bovine neutrophil ROS, and the most comprehensive comparative study of ROS assays under similar experimental conditions
Book review: Ted Grant: the permanent revolutionary
No full text"Ted Grant: The Permanent Revolutionary." Alan Woods. Wellred Publishing. April 2013. --- This work aims to cover the life and ideas of Ted Grant, one of the most well known figures in the international Marxist movement. Author Alan Woods aims to outlines Grant’s important theoretical contribution to Marxism and provide insights into a subject that remains a closed book to most political analysts even now. Gordon Bannerman feels that the book fails to fully engage with its subject, but Woods’ account does have some value in its often gritty portrayal of extra-parliamentary political movements
Differential alterations in the ability of bovine neutrophils to generate extracellular and intracellular reactive oxygen species during the periparturient period
No full textThe periparturient period of a dairy cow is associated with increased incidence and/or severity of certain infectious diseases, including mastitis. It is believed that the heightened physiological demands of calving and initiation of milk production contribute to a state of immunosuppression during this period. Previous studies have indicated that neutrophil production of reactive oxygen species (ROS), which is a critical element of the host innate immune response to bacterial infection, is impaired in the 1-2 week period following calving. However, whether there is comprehensive inhibition of ROS production or selective inhibition of particular ROS remains unknown. The present study provides evidence that neutrophils isolated from cows (n = 20) after calving have an increased capacity to generate intracellular ROS and ail impaired ability to release extracellular superoxide anion and hydrogen peroxide. Published by Elsevier Ltd
Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis
No full textStreptococcus uberis and Serratia marcescens are Gram-positive and Gram-negative bacteria, respectively, that induce clinical mastitis. Once initial host barrier systems have been breached by these pathogens, the innate immune system provides the next level of defense against these infectious agents. The innate immune response is characterized by the induction of pro-inflammatory cytokines, as well as increases in other accessory proteins that facilitate host recognition and elimination of the pathogens. The objective of the current study was to characterize the innate immune response during clinical mastitis elicited by these two important, yet less well-studied, Gram-positive and Gram-negative organisms. The pro-inflammatory cytokine response and changes in the levels of the innate immune accessory recognition proteins, soluble CD14 (sCD14) and lipopolysaccharide (LPS)-binding protein (LBP), were studied. Decreased milk output, induction of a febrile response, and increased acute phase synthesis of LBP were all characteristic of the systemic response to intramammary infection with either organism. Infection with either bacteria similarly resulted in increased milk levels of IL-1 beta, IL-8, IL-10, IL-12, IFN-gamma, TNF-alpha, sCD14, LBP, and the complement component, C5a. However, the duration of and/or maximal changes in the increased levels of these inflammatory markers were significantly different for several of the inflammatory parameters assayed. In particular, S. uberis infection was characterized by the sustained elevation of higher milk levels of IL-1 beta, IL-10, IL-12, IFN-gamma, and C5a, relative to S. marcescens infection. Together, these data demonstrate the variability of the innate immune response to two distinct mastitis pathogens
BDNF-TrkB signaling in striatopallidal neurons controls inhibition of locomotor behavior
No full textThe physiology of brain-derived neurotrophic factor signaling in enkephalinergic striatopallidal neurons is poorly understood. Changes in cortical Bdnf expression levels, and/or impairment in brain-derived neurotrophic factor anterograde transport induced by mutant huntingtin (mHdh) are believed to cause striatopallidal neuron vulnerability in early-stage Huntington's disease. Although several studies have confirmed a link between altered cortical brain-derived neurotrophic factor signaling and striatal vulnerability, it is not known whether the effects are mediated via the brain-derived neurotrophic factor receptor TrkB, and whether they are direct or indirect. Using a novel genetic mouse model, here, we show that selective removal of brain-derived neurotrophic factor-TrkB signaling from enkephalinergic striatal targets unexpectedly leads to spontaneous and drug-induced hyperlocomotion. This is associated with dopamine D2 receptor-dependent increased striatal protein kinase C and MAP kinase activation, resulting in altered intrinsic activation of striatal enkephalinergic neurons. Therefore, brain-derived neurotrophic factor/TrkB signaling in striatopallidal neurons controls inhibition of locomotor behavior by modulating neuronal activity in response to excitatory input through the protein kinase K/MAP kinase pathway
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