234 research outputs found
Resonative Mathematical practices
No full textThis document presents the research findings of Heidi D. Stokmo´s master's thesis in mathematics education. The thesis explores how migration in mathematics is experienced through the lens of "resonance," which refers to the dynamic interplay between the individual and the collective during mathematical practices.
The thesis begins with an introduction to the concept of resonance and its relevance to the study of migration in mathematics education. The author argues that resonance can provide insight into the affective and embodied dimensions of mathematical practices, dimensions described by Gutiérrez & Rogoff (2003), and can help in better understanding the dynamic components of an individual’s cultural-historical repertoire.
The thesis is divided into chapters six, each of which explores a different aspect of resonance in mathematical practices. Chapter 1 and 2 provides an overview of the background and theoretical framework of this research. Chapter 3 described the research methodology, while Chapter 4 and 5 presents an analysis of how resonance manifests in students' engagement with mathematical tasks and focuses on the findings of this study which are patterns of resonance and dissonance encountered in the mathematics classroom as well as the dynamic interplay of the various components.
The first section of chapter 6 focuses on the role of the teacher in facilitating resonance during mathematical practices, while the second section explores the implications of resonance for mathematics education more broadly. The thesis concludes with a discussion of the potential contributions of resonance theory to mathematics education research and practice, specifically its ability to notice resonance in both familiar and unfamiliar mathematical practices.
Overall, the thesis argues that resonance provides a valuable framework for understanding the dynamic dimensions of cultural-historical repertories in mathematics learning and teaching, specifically when investigating the experience of migration in mathematics. The author suggests that future research in mathematics education should continue to explore the concept of resonance and its potential implications for understanding and promoting more engaging and effective mathematical practices in diverse classrooms
Conception et réalisation d'un simulateur électronique de ligne de transport d'énergie électrique
No full textCette étude a pour but de concevoir et de réaliser un simulateur électronique de ligne de transport d'énergie électrique. En effet, les simulateurs de ligne sont des outils indispensables pour étudier et analyser les effets des perturbations survenant dans les réseaux électriques. Dû à leurs coûts élevés et à leurs manipulations incommodes, les simulateurs électriques et numériques de ligne représentent encore de sérieuses difficultés pour ce qui est de leurs utilisations. Par contre, le simulateur électronique de ligne surmonte ces problèmes tout en surpassant les performances des simulateurs électriques et numériques. Cette thèse comprend deux parties distinctes. La première partie analyse de façon théorique les différents paramètres des lignes de transport d'énergie électrique. Un programme numérique original, conçu par cette analyse, fournit les informations nécessaires à la réalisation du simulateur électronique de ligne. Dans la deuxième partie sont exposées la conception et la mise en réalisation des différentes parties du simulateur. Enfin, un chapitre est consacré à la vérification dynamique des performances du simulateur en examinant quelques cas pratiques
Prediction of effluent COD concentration of UASB reactor using kinetic models of monod, contois, second-order Grau and modified stover-kincannon
No full textAims: The aim of this study is predicting the effluent COD of UASB reactors with flowing mathematical models.
Materials and Methods: Weak industrial wastewater of the township, after passing screening unit, grit removal chamber and equalization tank, entered UASB reactor with volume of 144 m 3 (Length and width: 6 m; useful depth: 4 m). Analyses of laboratory parameters were done in accordance with water and wastewater standards.
Results: The reactor start-up started with hydraulic retention time of 14.4 d and organic loading rate of 0.04 Kg COD/m 3 .d or 0.02 Kg BOD 5 /m 3 .d which in 200 days, hydraulic retention time reached to 0.9 d and organic loading rate reached to 0.85 Kg COD/m 3 .d or 0.45 Kg BOD 5 /m 3 .d eventually, that the highest COD and BOD 5 removal efficiencies were observed up to 70% and 64%, respectively in the hydraulic retention time of 0.9 d. In the kinetic evaluation, the equations for effluent COD concentration prediction were obtained after calculating kinetic coefficients of Y, K d , K, K S and μmax in the Monod model; β and μmax in the Contois model; α, β and K 2(S) in the second-order Grau model and K B and U max in the modified Stover-Kincannon model.
Conclusion: The effluent COD concentration of reactor is a function of influent COD concentration of reactor in the modified Stover-Kincannon and second-order Grau models that have highest correlation coefficients while, it is a function of reactor′s solids retention time in Contois and Monod models
FIGURE 1 in The Black Flies (Diptera: Simuliidae) of Iran
No full textFIGURE 1. Map of Iran showing ecoregions recognized by the World Wildlife Federation (2013b) and collection sites 1 to 16 listed in Table 1. A = Central Persian Desert Basins. B = Arabian Desert and East Sahero-Arabian Xeric Shrublands. C = Kopet Dag Woodlands and Forest Steppe. D = Registan-North Pakistan Sandy Desert. E = Caspian Lowland Desert. F = Caspian Hyrcanian Mixed Forests. G = Elburz Range Forest Steppe. H = Zagros Mountains Forest Steppe. I = South Iran-Nubo Sindian Desert and Semi-Desert. J = Tigris-Euphrates Alluvial Salt Marsh. K = Kopet-Dag Semi-Desert. L = Azerbaijan Shrub Desert and Steppe. M = Eastern Anatolian Montane Steppe.Published as part of Khazeni, Atefeh, Adler, Peter H., Telmadareiiy, Zakieh, Oshaghi, Mohammad Ali, Vatandoost, Hasan, Abtahi, Seyed Mohammad & Lotfi, Abolfazl, 2013, The Black Flies (Diptera: Simuliidae) of Iran, pp. 67-74 in Zootaxa 3694 (1) on page 73, DOI: 10.11646/zootaxa.3694.1.5, http://zenodo.org/record/28432
Up-regulation of c-Jun contributes to induction of apoptosis by Adaphostin in human multiple myeloma cells
No full textPotential Anti-Apoptotic Impacts and Telomerase Activity of Royal Jelly on Different Tissues of Rats
No full textackground and Aim: Royal jelly (RJ) has a broad range of pharmaceutical activities, including antioxidant, anti-aging, anti-tumor, and anti-apoptotic. The current study aimed to investigate RJ impacts on cell survival by measuring the amount of telomerase enzyme, protein BCL2, and BAX in different tissues of rats.
Methods: In this study, male Wistar rats (n=21) were randomly divided into 3 groups; Group 1 was the control group. Group 2 and group 3 were treated with royal jelly at a concentration of 150 mg/kg and 300 mg/kg for 30 days, respectively. The contents of Bax, BCL-2, and telomerase in the tissues Brain, Liver, Kidney, and lymphocytes were measured using the ELISA method.
Results: Telomerase increased in all the tissues involved in both treatment groups compared to the control group; however, the changes were not statistically significant. Although BAX and BCL-2 proteins showed irregular patterns, the ratio of BAX/BCL-2 declined in almost all the studied tissues with a significant decline in the rats’ liver and kidney treated with RJ at the dose of 300 mg/kg and in the lymphocytes of the group administered 150 mg/kg of RJ.
Conclusion: RJ appears to have potential anti-apoptotic effects on the rats’ tissues studied via regulating the levels of BAX, BCL-2, and telomerase proteins. Regarding telomerase, its levels increased in a dose-dependent manner in all involved tissues. Concerning the ratio of BAX/BCL-2, it is sensible to conclude that RJ tends to positively impact the cell survival rate at the dose of 300 mg/kg in the brain, Liver, and Kidney. Nonetheless, this ratio decreased more significantly at the dose of 150 mg/kg in lymphocytes, showing more potential to survive brain cells in this concentration.
*Corresponding Author: Seyed-Hosein Abtahi-Eivary; Email: [email protected];
ORCID ID:0000-0001-5807-8933
Please cite this article as: Khani-Eshratabadi M, Talebpour A, Bagherzadeh A, Mehranfar P, Motallebzadeh Khanmiri J, Ghorbani M, Abtahi-Eivary SH. Potential Anti-Apoptotic Impacts and Telomerase Activity of Royal Jelly on Different Tissues of Rats. Arch Med Lab Sci. 2022;8:1-10 (e3). https://doi.org/10.22037/amls.v8.3653
Persian Treatises of Ali b. Muhammad Al-Jurjani (d.816/1413) on Islamic Theology, Philosophy, and Mysticism : a critical edition, introduction, and annotation
No full textL'objectif de ce travail de recherche est la restitution de l'héritage intellectuel d'un éminent savant de l'Iran médiéval tardif. ʻAlī ibn Muḥammad al-Jurjāni (740-816 h./1340-1413), surnommé al-Sayyid al-Sharīf, qui passe pour l'un des piliers scientifiques de son temps, fut un maître notoire des écoles de écoles de Shirāz et de Samarkand. Il est également auteur des nombreux commentaires et des gloses sur les ouvrages écrits par d'autres savants, dans le domaine des sciences rationnelles, littéraires et religieuses. Son Kitâb al-Ta'rîfât (Livre des définitions) reflète l'exhaustivité de sa connaissance dans toutes ces catégories de science. Le présent travail a recueilli ses traités en persan dans le domaine du Kalām (théologie), de la philosophie et de la mystique. Ce choix présente un double intérêt car il nous permet de présenter sur la base d'une vingtaine des authentiques manuscrits, ses écrits originaux rédigés en dehors du cadre du commentaire et de la glose, et adressés à un public très large dans le monde iranien, puisqu'ils étaient composés en persan. En tant que commentateur de Kitâb al-Mawâqif de 'Adud al-dîn al-Îjî, (m.756 /1355), sa maîtrise des subtilités des débats scholastiques en matière de la théologie philosophique est assez bien connue ; mais ici se trouvent réunies des nouvelles compositions de sa part dans ce domaine. Par ailleurs, est abordée ici une importante question restée à ce jour négligée et méconnue, à savoir la dimension mystique da sa pensée ; celle-ci le distingue nettement des autres théologiens de son temps. En effet, la connaissance intuitive soufie aussi bien que les questions issues de l'ésotérisme d'Ibn ‘Arabī (m.638/1240) et ses disciples fascinèrent notre auteur, dès sa jeunesse jusqu'à la fin de sa vie. L'introduction aux aspects divers de sa pensée va requérir une notice biographique et intellectuelle fournie à partir des nombreux documents qu'il y a à notre disposition. Nous l'avons rédigée de façon détaillée et scrupuleuse en nous intéressant à la description du climat culturel et intellectuel des pays où il résida, comme à ses rapports avec les personnages contemporains, à savoir ses maîtres, ses condisciples, les hommes de pouvoir, les autres savants notamment son concurrent Sa'd al-Din al-Taftazani (m.792/1390). Le portrait de ce personnage qui vécut à l'époque charnière entre la chute des Ilkhanides (vers.740/1340) et l'avènement de la dynastie safavide (907/1501) démontre une phase dans l'évolution de la sagesse en Iran, où la mystique spéculative s'apprêta à acquérir une consonance avec la philosophie, à la suite au désintérêt à l'égard du Kalām ash‘arite.The aim of this research is to restore the intellectual heritage of an Iranian prominent scholar who lived in the fourteenth and fifteenth centuries. As an erudite personality of his time and a famous teacher, ʻAlī ibn Muḥammad al-Jurjāni (740-816 H/1340-1413), Known as al-Sayyid al-Sharīf led important intellectual currents in the educational institutions of Shiraz and Samarkand. He is also the author of numerous commentaries and glosses on works written by other scholars in rational, literary, and religious sciences. Kitâb al-Ta'rîfât (Book of Definitions) reflects his comprehensive knowledge in all of these disciplines of science. The present work has collected and examined his treatises in Persian in the fields of Kalām (theology), philosophy, and mysticism. This choice offers a double advantage: It allows us to present, based on around twenty authentic manuscripts, his original writings that have composed outside the framework of commentary and gloss, and addressed a wide range of audience in the Iranian world since they were written in Persian. As a commentator on Kitâb al-Mawâqif by 'Adud al-dîn al-Îjî (d. 756/1355), his mastery of the intricacies of scholastic debates in the field of philosophical theology is fairly well known, but here new treatises by him on the subject are considered. Examining the mystical dimension of his thought is in fact another concern of the research, which has remained neglected and unrecognized to date. Jurjāni's mystical views distinguish him from other theologians of his time. Indeed, the Sufi intuitive knowledge, as well as the questions arising from the esotericism of 'Ibn ‘Arabī (d. 638/1240) and his disciples, fascinated Jurj?n?, from his youth until the end of his life. Introducing the various aspects of his thought requires a biographical and intellectual record provided from the many documents available to us. This is a mission that we are tasked to accomplish in a detailed and scrupulous manner, focusing on the zeitgeist or cultural and intellectual influences where he resided, as well as his relations with contemporary figures, namely his masters, his classmates, the men of power, the other scholars, in particular, his rival polymath Sa'd al-Din al-Taftazani (m.792/1390). The scholarly portrayal of al-Jurjāni who lived at the turning point between the fall of the Ilkhanids (circa740/1340) and the advent of the Safavid dynasty (907/1501) demonstrates a phase in the evolution of wisdom in Iran when speculative mysticism was about to acquire a consonance with philosophy, following the disinterest with regard to the Ash‘arite Kalām
25-hydroxyvitamin D concentrations in patients with optic neuritis as a clinically isolated syndrome and healthy controls
No full textObjectives: The onset of multiple sclerosis in the majority of the cases occurs as a clinically isolated syndrome (CIS). We sought to assess serum levels of 25-hydroxyvitamin D (25-OHD) in CIS patients and healthy controls.
Methods: In this cross-sectional study 40 patients (36 women and 4 men) with CIS manifesting as a single isolated optic neuritis and 40 Age- and sex-matched healthy controls (35 women and 5 men) were enrolled between late October 2010 and early March 2011. General vitamin D deficiency was defined as serum 25-OHD levels of lower than 20 ng/ml and was classified as mild (15 < 25-OHD <20 ng/ml), moderate (8 < 25-OHD <15 ng/ml), and severe (25-OHD <8 ng/ml).
Results: We found no difference in the median interquartile range [IQR] between CIS patients and controls (17.95 [10.40-29.13] vs. 17.00 [12.25-31.00]; P=0.57). However, when stratified by the levels of deficiency, among CIS patients a significantly higher proportion had severe vitamin D deficiency in comparison to healthy controls (20% vs. 2.5%; P=0.034). Nevertheless, the frequency of general (62.5% vs. 60%, P=0.82), mild (25% vs. 30%, P=0.80), and moderate (17.5% vs. 27.5%, P=0.42) vitamin D deficiency were not different between the two groups.
Conclusions: Our findings do not indicate any significant difference of serum 25-OHD between CIS patients and healthy controls. However, in our series severe vitamin D deficiency was more frequent among CIS patients
Intravitreal Diclofenac plus Bevacizumab versus Bevacizumab alone in treatment-naive diabetic macular edema: a randomized double-blind clinical trial
No full textThe aim of this study is to evaluate the short-term effects of a single intravitreal injection of 1.25 mg Bevacizumab combined with 300 lg/0.1 mL Diclofenac (IVB/D) versus 1.25 mg intravitreal Bevacizumab (IVB) alone in the treatment of naive diabetic macular edema (DME). In this prospective, randomized clinical trial, 80 eyes were included in the final analysis; 42 and 38 of which in the IVB and IVB/D groups, respectively. The primary outcome measure was a change in best-corrected visual acuity (BCVA) in logMAR at week 4. The secondary outcomes included changes in central macular thickness (CMT), macular volume, and potential injection-related complications. Significant improvement of BCVA was demonstrated in both study arms (mean reductions in LogMAR: -0.088 +/- 0.278, -0.228 +/- 0.330 for IVB and IVB/D, respectively). The difference in BCVA changes was in favor of IVB/D; however, not to a statistically significant level (P = 0.160). Significant reduction of CMT was documented in both study arms (mean reductions: 82.43 +/- 160.09 and 153.26 +/- 163.85 for IVB and IVB + IVD, respectively). Comparison of CMT changes between groups showed that IVB/D reduced CMT more than that of IVB (P = 0.04). Effects on macular volume corresponded to those of CMT. No injection-related complications or significant alterations in intraocular pressure were observed in any of the study arms. In treatment-naive DME, superiority of IVB/D combination therapy over IVB monotherapy may exist; especially as regards anatomical features. In our therapeutic arsenal for DME, IVD can be added as an adjunct to Bevacizumab
On the Performance of Passivr TMDs in Reducing the Damage in 2-D Concrete Structural Models
No full textAbstractPozzolanic materials, either naturally occurring or artificially made, have long been in practice since the early civilization. In recent years, the utilisation of pozzolanic materials in concrete construction has become increasingly widespread, and this trend is expected to continue in the years ahead because of technological, economical and ecological advantages of the materials. One of the latest additions to the ash family is palm oil fuel ash, a waste material obtained on burning of palm oil husk and palm kernel shell as fuel in palm oil mill boilers, which has been identified as a good pozzolanic material. This paper highlights test results on the performance behavior of palm oil fuel ash (POFA) in reducing the heat of hydration of concrete. Two concrete mixes namely OPC concrete i.e. concrete with 100% OPC as control, and POFA concrete i.e. concrete with 30% POFA and 70% OPC were prepared, and the temperature rise due to heat of hydration in both the mixes was recorded. It has been found that palm oil fuel ash not only reduced the total temperature rise but also delayed the time at which the peak temperature occurred. The results obtained and the observation made clearly demonstrate that the partial replacement of cement by palm oil fuel ash is advantageous, particularly for mass concrete where thermal cracking due to excessive heat rise is of great concern
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