8 research outputs found
Evaluation of primary students\u27 speech performances in the first educational period
No full textGovor je sredstvo, s katerim se ljudje povezujemo in ohranjamo stike. Z njim kažemo svojo osebnost. Govorjenje je ena od štirih sporazumevalnih dejavnosti, zato ga pri jezikovnem pouku načrtno razvijamo. Govorjenje se razvija tudi z govornim nastopanjem (v nadaljevanju GN), s katerim se soočijo že prvošolci. Del GN je njegovo vrednotenje.
V teoretičnem delu smo naprej opredelili govor, govorno nastopanje in faze GN. Opredelili smo vrednotenje in povratno informacijo ter ocenjevanje.
V empiričnem delu smo predstavili rezultate raziskave. Da bi ugotovili, kolikšen pomen učitelji v 1. vzgojno-izobraževalnem obdobju (v nadaljevanju VIO) namenjajo GN, kako pogosto jih učenci izvajajo, pri katerih predmetih in kdo ter kako vrednoti učenčev GN, smo spletni anketni vprašalnik posredovali učiteljem, ki poučujejo v prvih treh razredih osnovne šole.
Rezultati raziskave so pokazali, da učenci najpogosteje izvajajo GN pri slovenščini, pri čemer je tema najpogosteje opis osebe, živali ali igrače. Večina učiteljev se pri GN osredotoča na vsebino povedanega in jo vrednoti. Velika večina učiteljev meni, da je zelo pomembno oz. pomembno, da učenci izvajajo GN tudi v 1. VIO. Pri mnenju o pomembnosti GN ni bilo statistično pomembnih razlik med učitelji, ki poučujejo v 1., 2. in 3. razredu, prav tako ni bilo statistično pomembnih razlik med mnenji in delovno dobo teh učiteljev. Rezultati so pokazali, da so tudi učenci 1. VIO vključeni v sam proces vrednotenja GN. Najpogosteje podajo povratno informacijo na sošolčev GN, pri čemer se tudi učenci osredotočijo na vsebino povedanega. Tudi nastopajoči učenec vrednoti svoj GN. Pri rezultatih ni bilo statistično pomembnih razlik pri tem, kdo vrednoti GN glede na razred. Namreč, v vseh treh razredih 1. VIO so GN vrednotili učitelj, sošolci in nastopajoči učenec. Raziskava je pokazala, da je delež med deležniki, ki najpogosteje vrednotijo GN, precej izenačen.Speech is a means used to connect and maintain contact. It also portrays our personality. Speech is one of the four communication activities, which is why schools plan its development in languages class. It is also developed with speech performances (hereinafter: SP), which are given as early as in the first grade. A part of SPs is their evaluation.
In the theoretical part, we first defined speech, speech performance (SP) and phases of a SP. Evaluation, feedback and assessment were also determined.
In the empirical part, we used the quantitative research approach. In order to determine what importance teachers in the first educational period attribute to SPs, how often pupils are asked to give them, in what subject they are asked to give them and who and how evaluates pupils\u27 SPs, we sent an online survey to teachers of the first three grades of primary school.
Research results showed that pupils most commonly give SPs in Slovene class, where they most frequently describe people, animals or toys. Most teachers focus on and evaluate the content of the speech. A vast majority of them believes that it is either very important or important for pupils to give SPs as early as in the first educational period. When it came to their opinion on the importance of SPs, there were no statistically significant differences between first-, second- and third-grade teachers. The same applied to their opinions and length of service. The results showed that pupils of the first educational period are also included in the SP evaluation process. They most commonly give feedback on their classmates\u27 SPs, focusing on the content of the speech. The pupil giving the speech also evaluates their own speech. There were no statistically significant differences in SP evaluators in terms of the grade. In all three grades of the first educational period, the teacher, classmates and the pupil giving the SP evaluated the speech. Research showed that the proportion between those who most commonly evaluate SPs is considerably equal
Hypersensitivity to D. pteronyssinus in librarians
No full textAutori su na 4 bolesnika s kroničnom opstruktivnom plućnom bolesti, zaposlena u knjižnici, proučavali preosjetljivost tipa I i tipa III (Arthusova reakcija, alergijski pneumonitis). Budući da su uz preosjetljivost tipa I našli i preosjetljivost tipa III, preporučuju da se za otkrivanje tipa preosjetljivosti upotrijebe i »in vitro« testovi (RIST, RAST, dvostruka imunodifuzija i imunoelektroforeza).Hypersensitivity to D. pteronyssinus was studied in four librarians with chronic obstructive lung disease. Medical histories, clinical data and the results of the diagnostic in vitro and in vivo tests are presented. The subjects had elevated total IgE and specific IgE antibodies. Three subjects had type I hypersensitivity and one subject type III. Type III hypersensitivity (Arthus' reaction) was confirmed by double diffusion-in-gel determination of serum precipitins to D. pteronyssinus. The author suggests that to detect type III hypersensitivity to D. pteronyssinus both the in vitro and in vivo allergological tests (RIST, RAST, double immunodiffusion test) be used in order to complement a clinical examination and lung function tests
TREATMENT OF PRIMARY PLASMA CELL LEUKAEMIA
No full textBackground. The author describes long-term survival in 3 patients with primary plasma cell leukaemia (PL) after different therapeutic regimen and maintenance treatment with interferon alpha (INF).Patients and treatment. In a 52-year-old male patient, a partial remission of PL was achieved after 6 months of treatment with melphalan and prednisone. The patient did not consent to stem cell transplantation (SCT). An 86-year-old female patient with PL achieved a complete remission after 6 months of treatment with vincristine, doxorubicin and dexamethasone. A 31-year-old male patient experienced a complete remission of PL after 6 months of treatment with cyclophosphamide, vincristine, doxorubicin, methilprednisone, followed by autologous SCT. All three patients were placed on maintenance therapy with INF-2b (Intron A) 3 × 106 IU given subcutaneously on two days per week. In the 52-year-old man, the remission lasted 9 months and in the woman 23 months, whereupon they developed a relapse with signs of disseminated plasmacytoma. In both patients the former chemotherapy was applied again, resulting in a slight improvement. The man died 37 months and the woman 43 months after the diagnosis of PL, while the youngest patient has been in complete remission for 82 months.Conclusions. Long remission achieved in our patients confirmed the favourable effect of INF in terms of prolongation of the remission duration in this patients. The effect of maintenance treatment with INF is usually directly dependent on the degree of remission induced by different therapeutic regimen.</p
In search of a happy ending Documentary / In search of a happy ending Documentary
No full textDokumentarni film V iskanju srečnega konca je socialno-umetniški projekt, osnovan na prijateljstvu. Louis Giannetti v svojem delu Razumeti film piše o zgodbi kot o besedi tisočih pomenovza producenta je zgodba lastnina, nekaj, kar ima tržno vrednost, za scenarista pisanje scenarija, za režiserja umetniški medij, za igralca sredstvo. Toda zgodba za glavni lik dokumentarnega filma je v tem primeru njegovo življenje. In upravljanje s tako zgodbo – torej z življenjem živečega – je težek izziv za režiserja. Kako jo prikazati? Koliko sploh prikazati? Kje (ne)intervenirati? Kot režiserki mi je bilo pomembno, da zgodbo glavnega lika umestim v družbeni kontekst današnjega časa. Delo z nematerialnim oziroma z živo materijo je bilo razgibano in nepredvidljivoravno nepredvidljivost, dvorezen meč dokumentarnega filma, na koncu da tisto dodano vrednost, ki jo išče vsak režiser, ki se materializira v protagonista, režiserja in gledalca in ki vse tri na koncu postavi na skupno raven. Kot avtorici projekta upam, da mi je to uspelo.Documentary film In search of a happy ending is a socially engaged art project based on friendship. In his work Understanding Movies, Louis Giannetti writes that story is a word of a thousand meaningsto the producer story is property, or better, something that has commercial value, to the screenwriter a script, to the director an art medium, and to the actor an asset. But in this case, the story behind the main character of the documentary is his life. And directing such a story - the life of a living person - is a difficult challenge for the director. How to present it? How much should you show? Where to (not) intervene? It was important to me as the director to stay current in the social context. Working with living matter was dynamic and unpredictablethis unpredictability, the two-edged sword of the documentary film, ultimately contributes to the added value that every director seeks and which materializes in the protagonist\u27s, director\u27s and viewer\u27s emotions which puts all three of them on the same level. As the author of the project, I hope that I succeeded in evoking these emotions
Multiple Myeloma Treatment in Real-world Clinical Practice: Results of a Prospective, Multinational, Noninterventional Study
No full textMultiple myeloma (MM) remains an incurable disease, with little information available on its management in real-world clinical practice. The results of the present prospective, noninterventional observational study revealed great diversity in the treatment regimens used to treat MM. Our results also provide data to inform health economic, pharmacoepidemiologic, and outcomes research, providing a framework for the design of protocols to improve the outcomes of patients with MM. Background: The present prospective, multinational, noninterventional study aimed to document and describe real-world treatment regimens and disease progression in multiple myeloma (MM) patients. Patients and Methods: Adult patients initiating any new MM therapy from October 2010 to October 2012 were eligible. A multistage patient/site recruitment model was applied to minimize the selection bias; enrollment was stratified by country, region, and practice type. The patient medical and disease features, treatment history, and remission status were recorded at baseline, and prospective data on treatment, efficacy, and safety were collected electronically every 3 months. Results: A total of 2358 patients were enrolled. Of these patients, 775 and 1583 did and did not undergo stem cell transplantation (SCT) at any time during treatment, respectively. Of the patients in the SCT and non-SCT groups, 49%, 21%, 14%, and 15% and 57%, 20%, 12% and 10% were enrolled at treatment line 1, 2, 3, and ≥ 4, respectively. In the SCT and non-SCT groups, 45% and 54% of the patients had received bortezomib-based therapy without thalidomide/lenalidomide, 12% and 18% had received thalidomide/lenalidomide-based therapy without bortezomib, and 30% and 4% had received bortezomib plus thalidomide/lenalidomide-based therapy as frontline treatment, respectively. The corresponding proportions of SCT and non-SCT patients in lines 2, 3, and ≥ 4 were 45% and 37%, 30% and 37%, and 12% and 3%, 33% and 27%, 35% and 32%, and 8% and 2%, and 27% and 27%, 27% and 23%, and 6% and 4%, respectively. In the SCT and non-SCT patients, the overall response rate was 86% to 97% and 64% to 85% in line 1, 74% to 78% and 59% to 68% in line 2, 55% to 83% and 48% to 60% in line 3, and 49% to 65% and 36% and 45% in line 4, respectively, for regimens that included bortezomib and/or thalidomide/lenalidomide. Conclusion: The results of our prospective study have revealed great diversity in the treatment regimens used to manage MM in real-life practice. This diversity was linked to factors such as novel agent accessibility and evolving treatment recommendations. Our results provide insight into associated clinical benefits. © 2018 The Author
