8,314 research outputs found
Evaluation of adherence to guidelines to prevent perinatal infections in Oregon
No full textprepared by: Mark Schmidt (PhD, MPH; ABCs Surveillance Officer, Acute & Communicable Disease Program), Sean Schafer (MD; Medical Epidemiologist, HIV/STD/TB Program), Juventila Liko (MD; Epidemiologist, Immunization Program), Maureen Cassidy (MPH; Epidemiologist, Immunization Program), and Ann Thomas (MD, MPH; ABCs Principal Investigator, Acute & Communicable Disease Program).Title from PDF caption (viewed on October 16, 2020)."Adapted from the Protocol for the Evaluation of Adherence to the 2002 Revised Guidelines for the Prevention of Perinatal GBS Disease (Unpublished), by Christina Phares, PhD, Stephanie Schrag, DPhil, Elizabeth Zell, MStat, Katie Arnold, MD, Allen Craig, MD, Ruth Lynfield, MD, Janet Mohle-Boetani, MD, Aaron Roome, PhD, and Ann Thomas, MD, MPH, for the Active Bacterial Core Surveillance Team."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (page 10).Mode of access: Internet from the Oregon Government Publications Collection.Text in English
POTENTIOMETRIC AND SPECTROSCOPIC STUDIES ON COPPER(II) AND ZINC(II) COMPLEXES OF PEPTIDES CONTAINING BIS(IMIDAZOLYL) LIGANDS
No full textCopper- and zinc-(ii) complexes of various bis(imidazolyl) ligands have been studied by potentiometric, visible and EPR Spectroscopic methods. The ligands included bis(imidazol-2-yl)methane (CH(2)R(2)), bis(imidazol-2-yl)methylamine (R(2)CHNH(2)) and 3.3-[bis(imidazol-2-yl)]propionic acid (R(2)CHCH(2)CO(2)H) and peptides in which the bis(imidazolyl) groups are coupled at the C-terminu, MeCO-Pro-Leu-Gly-NHCHR(2) and Bu(t)OCO-Pro-His-Gly-NHCHR(2) or the N-terminus, R(2)CHCH(2)CO-lle-Ala-GIy-OEt and R(2)CHCH(2)CO-Ile-His-Gly-OEt (where R = imidazol-2-yl). The data revealed that stable mono- and bis-(ligand) complexes are formed with all ligands and the imidazole nitrogensare the main metal binding sites. Tridentate co-ordination of R(2)CHNH(2) was concluded to exist in the equimolar solutions of copper(II) and R(2)CHNH(2), which results in the formation of a dinuclear mixed-0hydroxo-complex with imidazole bridging. Deprotonation of the co-ordinated water molecules was also observed around the physiological pH range in the zinc(II)-R(2)CHNH(2) complex. The involvement of the side-chain imidazble residues of the peptides Bu(t)OCO-Pro-His-Gly-NHCHR2 and especially R(2)CHCH(2)CO-Ile-His-GIy-OEt in co-ordination has also been demonstrated
ATLAS Distributed Data management Operations
No full textATLAS Distributed Data Management (DDM) service is developed for data transfer between ATLAS sites and for data cataloguing. The Data Management Software (SW) is based on DQ2 and end-users tools (aka dq2_get package). In this paper we address the issue of DDM day-by-day operation, DDM operations team organization, roles and responsibilities of Tier-1s and Tier-2s DDM coordinators
Anionic dendritic polyglycerol for protein purification and delipidation
No full textMembrane proteins are important biomolecular targets in drug discovery. Different membrane mimetics and purification strategies have been developed; however, investigating membrane proteins in their native environment remains challenging. Here, we introduce an anionic, dendritic polyglycerol sulfate (dPGS-PCL) to membrane protein research. dPGS-PCL enables the purification of soluble, protein-containing membranes. We examine the utility of dPGS-PCL to study membrane protein delipidation and function in detail. Our data show that protein yields and delipidation outcomes depend on the properties of both membrane mimetics and membranes. This allows us to re-evaluate the importance of mildly delipidating detergents for the purification of functional membrane proteins. In addition to bacterial membrane proteins, dPGS-PCL enables the purification of a functional G-protein-coupled receptor (GPCRs). We anticipate that dPGS-PCL will enable the discovery of custom-made membrane mimetics and purification protocols for future applications in membrane protein research
NaViA : a program for the visual analysis of complex mass spectra
No full textMotivation:
Native mass spectrometry is now a well-established method for the investigation of protein complexes, specifically their subunit stoichiometry and ligand binding properties. Recent advances allowing the analysis of complex mixtures lead to an increasing diversity and complexity in the spectra obtained. These spectra can be time-consuming to tackle through manual assignment and challenging for automated approaches.
Results:
Native Mass Spectrometry Visual Analyser is a web-based tool to augment the manual process of peak assignment. In addition to matching masses to the stoichiometry of its component subunits, it allows raw data processing, assignment and annotation and permits mass spectra to be shared with their respective interpretation.
Availability and implementation:
NaViA is open-source and can be accessed online under https://navia.ms. The source code and documentation can be accessed at https://github.com/d-que/navia, under the BSD 2-Clause licence.
Supplementary information:
Supplementary data are available at Bioinformatics online
Search for the associated production of the Higgs boson with a top-quark pair (vol 9, 087, 2014): Erratum
No full textErratum to: JHEP09(2014)087Khachatryan, V., Sirunyan, AM., Tumasyan, A., Adam, W., Bergauer, T., Dragicevic, M., Ero, J., Fabjan, C., Friedl, M., Fruhwirth, R., Ghete, VM., Hartl, C., Hormann, N., Hrubec, J., Jeitler, M., Kiesenhofer, W., Knunz, V., Krammer, M., Kratschmer, I., Liko, D., Mikulec, I., Rabady, D., Rahbaran, B., Rohringer, H., Schofbeck, R., Strauss, J., Taurok, A., Treberer-Treberspurg, W., The CMS Collaboratio
Nuclear modification factor of D-0 mesons in PbPb collisions at root s(NN)=5.02 TeV
No full textThe transverse momentum (p(T)) spectrum of prompt D-0 mesons and their antiparticles has been measured via the hadronic decay channels D-0 -> K- pi(+) and (D) over bar (0) -> K+ pi(-) in pp and PbPb collisions at a centre-of-mass energy of 5.02 TeV per nucleon pair with the CMS detector at the LHC. The measurement is performed in the D-0 meson p(T) range of 2-100GeV/c and in the rapidity range of vertical bar y vertical bar < 1. The pp (PbPb) dataset used for this analysis corresponds to an integrated luminosity of 27.4 pb(-1) (530 mu b(-1)). The measured D-0 meson p(T) spectrum in pp collisions is well described by perturbative QCD calculations. The nuclear modification factor, comparing D-0 meson yields in PbPb and pp collisions, was extracted for both minimum-bias and the 10% most central PbPb interactions. For central events, the D-0 meson yield in the PbPb collisions is suppressed by a factor of 5-6 compared to the pp reference in the p(T) range of 6-10GeV/c. For D-0 mesons in the high-p(T) range of 60-100GeV/c, a significantly smaller suppression is observed. The results are also compared to theoretical calculations. (C) 2018 The Author(s). Published by Elsevier B.V
FIG. 6 in Mortality in a predator-free insular environment: the dwarf deer of Crete
No full textFIG. 6. Mortality profiles (dx) for Candiacervus ropalophorus from Gerani 4 (top left, actual numbers for all ages; bottom left, juveniles only) and Candiacervus sp. II from Liko (top right, all ages). Bottom right, reconstruction of Can. ropalophorus by Alexis Vlachos.Published as part of van der Geer, Alexandra A. E., Lyras, George A., MacPhee, Ross D. E., Lomolino, Mark & Drinia, Hara, 2014, American Museum Novitates 2014 (3807) on page 1, DOI: 10.1206/3807.1, http://zenodo.org/record/536750
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