8,776 research outputs found
Interview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American City
No full textInterview with Nicholas Christopher, author of Somewhere in the Night: Film Noir and the American Cit
The Making of an Indigenous Language Teacher: Reclaiming our Hopi Heritage of Thinking, Teaching and Learning
No full textThe current political and social environment and the more ominous events unfolding across aboriginal Indigenous homelands—locally, nationally and globally—is what the Hopi people refer to as koyanisqatsi, life out of balance and which has been recounted as recurrent in the history of the human experience. It is a prominent theme in their Emergence story transported across time by each succeeding generation of Hopi through the oral tradition. The Hopi number just over 14,000 of which half maintain a permanent residence on part of their aboriginal homelands in northeastern Arizona and continue to carry out the cultural traditions of their ancestors. Thus the words of dedication, “For the Hopi people who have maintained a firm belief in and adherence to the Hopi way of life in order that succeeding generations of Hopi will remain a distinct people,” (Author 1, 2008, p. 5) represent and represents the Hopi way of life as the resilient and reliable guiding source toward an unknown future. The paramount challenge is for the Hopi people to maintain community cohesiveness and unity, a moral existence in the natural world, and spiritual fulfillment on behalf of all people, all living things—the commitment made with Maasaw, Guardian Spirit of the Hopi Fourth World at the time of Emergence—within the context of a life out of balance. Nevertheless, our individual and collective responses are premised in our sense of accountability to our Creator as stewards of Mother Earth, and responsibility to the next generation to ensure cultural and linguistic survival and continuity (Author 2, 2016). “Very little has been written about how contemporary Native people have come into our Indigenous selves through the work we do. This is particularly true of Indigenous educators” (Cajete, 2015, p.1). In this paper, we share and situate our “stories”—our personal and professional trajectories in two foundational Hopi concepts: itaaqatsimkiwa—our lifeline; itaatumakmakiwa—our lifework, concepts that are understood as “preordained” and “predestined” in leading each of us toward finding our “true vocation” to (p. 1). We engage in an analysis of our experiences as a manifestation of self-empowerment and voice (Ruiz, 1991). It is “the work that we do” which brought us together and nurtures our commitment to attending to our heritage language and culture. Cajete (2015) describes this process of reclaiming an Indigenous heritage of thinking, teaching and learning as the making of an Indigenous teacher. Cajete, G. A. (2015). Indigenous community: Rekindling the teachings of the seventh fire. St. Paul, MN: Living Justice Press. Author 2. (2016). Unpublished Reflection paper. Author 1. (2008). “Becoming ‘fully’ Hopi: The role of the Hopi language in the contemporary lives of Hopi youth—A Hopi case study of language shift and vitality.” Unpublished doctoral dissertation. American Indian Studies Program, University of Arizona, Tucson. Ruiz, R. (1991). Empowering linguistic minority children. In In C.E. Sleeter (Ed.), Empowerment through multicultural education. Albany, NY: State University of New York Press
Resurrecting the Author
No full textPresentation of Nicholas Wolterstorff\u27s Paper Resurrecting the Author with time after for questions beginning at 18:00
Epigenetic regulation of bone mass
No full textOsteoporosis, characterised by low bone mass, poor bone structure, and an increased risk of fracture, is a major public health problem. There is increasing evidence that the influence of the environment on gene expression, through epigenetic processes, contributes to variation in BMD and fracture risk across the lifecourse. Such epigenetic processes include DNA methylation, histone and chromatin modifications and non-coding RNAs. Examples of associations with phenotype include DNA methylation in utero linked to maternal vitamin D status, and to methylation of target genes such as OPG and RANKL being associated with osteoporosis in later life. Epigenome-wide association studies and multi-omics technologies have further revealed susceptibility loci, and histone acetyltransferases, deacetylases and methylases are being considered as therapeutic targets. This review encompasses recent advances in our understanding of epigenetic mechanisms in the regulation of bone mass and osteoporosis development, and outlines possible diagnostic and prognostic biomarker applications
Cardiovascular safety of calcium, magnesium and strontium: what does the evidence say?
No full textCalcium, magnesium and strontium have all been implicated in both musculoskeletal and cardiovascular health and disease. However, despite these three elements being closely chemically related, there is marked heterogeneity of their characteristics in relation to cardiovascular outcomes. In this narrative review, we describe the relevant evidential landscape, focusing on clinical trials where possible and incorporating findings from observational and causal analyses, to discern the relative roles of these elements in musculoskeletal and cardiovascular health. We conclude that calcium supplementation (for bone health) is most appropriately used in combination with vitamin D supplementation and targeted to those who are deficient in these nutrients, or in combination with antiosteoporosis medications. Whilst calcium supplementation is associated with gastrointestinal side effects and a small increased risk of renal stones, purported links with cardiovascular outcomes remain unconvincing. In normal physiology, no mechanism for an association has been elucidated and other considerations such as dose response and temporal relationships do not support a causal relationship. There is little evidence to support routine magnesium supplementation for musculoskeletal outcomes; greater dietary intake and serum concentrations appear protective against cardiovascular events. Strontium ranelate, which is now available again as a generic medication, has clear anti-fracture efficacy but is associated with an increased risk of thromboembolic disease. Whilst a signal for increased risk of myocardial infarction has been detected in some studies, this is not supported by wider analyses. Strontium ranelate, under its current licence, thus provides a useful therapeutic option for severe osteoporosis in those who do not have cardiovascular risk factors
Heritability and Linkage Analysis of Appendicitis Utilizing Age at Onset
No full textAppendicitis usually afflicts the young, but there is a large tail in the distribution of onset age. The genetics of this disease are still not well understood. A heritability analysis and genome wide linkage analysis of a large twin dataset was undertaken. Treating age of onset of appendicitis as a censored survival trait revealed a heritability of 0.21, and found evidence of linkage to Chromosome 1p37.3. Author(s): Christopher Oldmeadow 1 * | Kerrie Mengersen 2 | Nicholas Martin 3 | David L. Duffy
The Blase and the Adventure - Seachange Through Simmel
No full textThe aim of this paper is to not engage thoroughly with the Australian movement that has been loosely termed as Seachange, but rather, it is to critically engage with data emerging from this phenomenon using social theoretical perspective from Georg Simmel. The reason for proceeding with this analysis is to provide further credence to the already well acknowledged brilliance of Simmel’s social theory. Furthermore, by doing so, we will be see that this author’s work is more than useful for examining the movements of post/late/high modernity. This is perhaps largely due to the ability of Simmel’s theory to transcend boundaries between disciplines and provide a ‘variety of theoretical perspectives’ (Featherstone, 1991, p2). However, further to this, Simmel’s sociology appears to have an uncanny ability to correspond with much of what is being written on the subject of the aesthetic postmodern culture in contemporary times. Such comparison advocated Simmel’s title as a ‘postmodernist in advance of the discourse’ (Weinstein and Weinstein, 1991, p152). It is not the case of this paper to engage deeply in such a discourse, rather, the simple purpose is to illustrate effectively the deepness of Simmel’s analysis which provides him with the aforementioned title. By using interview data collected by the author himself and through another project run by Dowling (2004), it will be shown that Simmel’s work in the area of the metropolis and leisure, provides sufficient and engaging analysis of Seachange
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Six New and Recent Works for Solo Cello in Recording and Discussion
No full textABSTRACT OF THE DISSERTATIONSix New and Recent Works for Solo Cello in Recording and Discussionby Ashley Melynda WaltersDoctor of Musical Arts in Contemporary Music PerformanceUniversity of California, San Diego, 2013Professor Charles Curtis, ChairThe focus of this dissertation project was on the learning, performance, and recording of six works for solo cello: Sequenza XIV by Luciano Berio, Plainsound-Litany by Wolfgang von Schweinitz, Another Secular Calvinist Creed by Andrew McIntosh, Sweet Bay Magnolia with Berry Clusters by Wadada Leo Smith, For Stephanie (on our wedding day) by Nicholas Deyoe, and another anxiety by Nicholas Deyoe. The following writing serves as a supporting document to this project, concentrating on the collaborations between the author and Schweinitz, McIntosh, Smith, and Deyoe. This paper will address the variations in the collaborative process with each composer, commenting on how the dedication of the piece to the author affected the inspiration for writing the piece and the notation, where relevant. In addition, the influence of the collaborative process on the author's interpretation of each piece will be discussed. Finally, where applicable, these aspects and their influence on the listening experience will be addressed
Nicholas de Monchaux: Local Code / Real Estates
No full textNicholas de Monchaux is an architect and urbanist whose work explores the intersections between nature, technology, and the city. He is the author of Spacesuit: Fashioning Apollo (MIT Press, 2011), an architectural history of the Apollo 11 spacesuit. He is Assistant Professor of Architecture and Urban Design at UC Berkeley. The work of his design studio has been exhibited widely and is currently being featured in the US Pavillion of the 13th Venice Biennale
Nicholas Meyer: 10-31-1979
No full textNicholas Meyer is a screenwriter, producer, director, and author, and a graduate of the University of Iowa. He is the author of the screenplay the Seven Per Cent Solution and co-author of The Black Orchid. He begins the interview by discussing his professional career as both a film writer/director and a novelist. He then talks about how he began writing novels, and discusses the research that goes into his novels. Meyer continues by discussing his movie Time After Time and concludes the interview by listing prominent teachers and writing influences.Archived web contentSUNY BrockportWriters Forum Video
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