171,627 research outputs found
C-FOREST: Parallel Shortest-Path Planning with Super Linear Speedup
No full textIn (Otte and Correll 2013) we present C-FOREST, a parallelization framework for single-query sampling-based shortest-path planning algorithms. C-FOREST has been observed to have super linear speedup on many problems, e.g., paths of quality Ltarget are found 350X faster by 64 CPUs working in parallel than by 1 CPU. In (Otte and Correll 2013) C-FOREST is tested in conjunction with the RRT* algorithm. In the current work we perform additional experiments that show C-FOREST provides similar advantages when used conjunction with the SPRT algorithm. This reinforces our original claim that C-FOREST is generally applicable to a wide range of sampling based motion planning algorithms
Dedication of The Correll Center for Teacher Education and Learning
No full textDedication of the Correll Center for Teacher Education and Learning
Corrigendum: Network analysis of the relationship between depressive symptoms, demographics, nutrition, quality of life and medical condition factors in the Osteoarthritis Initiative database cohort of elderly North-American adults with or at risk for osteoarthritis (Journal of Physical Chemistry (2019) DOI: 10.1017/S204579601800077X)
No full textThe above article was originally submitted to Epidemiology and Psychiatric Sciences with the incorrect author name listed for the second author. The correct surname for the second author is Ai Koyanagi (and not Ai Konayagi). The authors would like to apologise for this error. © Cambridge University Press 2019
Adjunctive minocycline in schizophrenia: What one well-conducted study can tell us (and what it can't)
No full textCorrigendum: Network analysis of the relationship between depressive symptoms, demographics, nutrition, quality of life and medical condition factors in the Osteoarthritis Initiative database cohort of elderly North-American adults with or at risk for osteoarthritis (Journal of Physical Chemistry (2019) DOI: 10.1017/S204579601800077X)
No full textThe above article was originally submitted to Epidemiology and Psychiatric Sciences with the incorrect author name listed for the second author. The correct surname for the second author is Ai Koyanagi (and not Ai Konayagi). The authors would like to apologise for this error
Erratum:Lifestyle interventions for weight management in people with serious mental illness: A systematic review with meta-analysis, trial sequential analysis, and meta- regression analysis exploring the mediators and moderators of treatment effects (Psychotherapy and Psychosomatics (2019) (1-13) DOI: 10.1159/000502293)
No full textIn the article by Speyer H., Jakobsen A.S., Westergaard C., Norgaard H.C.B., Pisinger C., Krogh J., Hjorthoj C., Nordentoft M., Gluud C., Correll C.U., Jorgensen K.B. entitled "Lifestyle Interventions for Weight Management in People with Serious Mental Illness: A Systematic Review with Meta-Analysis, Trial Sequential Analysis, and Meta- Regression Analysis Exploring the Mediators and Moderators of Treatment Effects" [Psychother Psychosom. 2019 Sep 13: 1-13, DOI: 10.1159/000502293], the correct sequence of the authors should read as follows: Speyer H., Jakobsen A.S., Westergaard C., Norgaard H.C.B., Jorgensen K.B., Pisinger C., Krogh J., Hjorthoj C., Nordentoft M., Gluud C., Correll C.U.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A meta-analysis of temperament and character dimensions in patients with mood disorders: Comparison to healthy controls and unaffected siblings
No full textCloninger's psychobiological model of personality has been extensively applied to subjects affected by mood disorders (MOOD). However, most studies are widely heterogeneous in terms of sample size, methods of assessment, and selection of participants.
We conducted a systematic review of literature and a random effects meta-analysis of studies comparing at least two of the following groups: (a) adults with a primary MOOD diagnosis (Bipolar Disorder (BP) or major depressive disorder (MDD)), (b) their unaffected siblings (SIB) or (c) healthy subjects (HS), and reporting quantitative results from the Tridimensional Personality Questionnaire (TPQ) or the Temperament and Character Inventory (TCI).
Subgroup, sensitivity and meta-regression analyses were also conducted.
High Harm Avoidance and low Self-Directedness were consistently associated with MOOD and SIB samples. BP was characterized by higher scores in Novelty Seeking and Self-Transcendence than HS, SIB and MDD. Age seemed to have a negative effect on Novelty Seeking and a positive effect on Harm Avoidance, Cooperativeness and Self-Transcendence. An euthymic mood state was associated with reduced Harm Avoidance, but increased Reward Dependence, Self-Directedness and Cooperativeness.
imitations: The quality of the included studies varied and was relatively low. Moreover, publication bias and heterogeneity in the distribution of effect sizes may also have limited our results.
High Harm Avoidance and Low Self-Directedness may be trait markers for MOOD in general, while high Novelty Seeking and high Self-Transcendence may be specific to BP. Future studies are needed to disentangle the state-trait effect of each personality dimension
Network analysis of the relationship between depressive symptoms, demographics, nutrition, quality of life and medical condition factors in the Osteoarthritis Initiative database cohort of elderly North-American adults with or at risk for osteoarthritis
No full textAims:
A complex interaction exists between age, body mass index, medical conditions, polypharmacotherapy, smoking, alcohol use, education, nutrition, depressive symptoms, functioning and quality of life (QoL). We aimed to examine the inter-relationships among these variables, test whether depressive symptomology plays a central role in a large sample of adults, and determine the degree of association with life-style and health variables.
Methods:
Regularised network analysis was applied to 3532 North-American adults aged ⩾45 years drawn from the Osteoarthritis Initiative. Network stability (autocorrelation after case-dropping), centrality of nodes (strength, M, the sum of weight of the connections for each node), and edges/regularised partial correlations connecting the nodes were assessed.
Results:
Physical and mental health-related QoL ( M = 1.681; M = 1.342), income ( M = 1.891), age ( M = 1.416), depressive symptoms ( M = 1.214) and education ( M = 1.173) were central nodes. Depressive symptoms’ stronger negative connections were found with mental health-related QoL (−0.702), income (−0.090), education (−0.068) and physical health-related QoL (−0.354). This latter was a ‘bridge node’ that connected depressive symptoms with Charlson comorbidity index, and number of medications. Physical activity and Mediterranean diet adherence were associated with income and physical health-related QoL. This latter was a ‘bridge node’ between the former two and depressive symptoms. The network was stable (stability coefficient = 0.75, i.e. highest possible value) for all centrality measures.
Conclusions:
A stable network exists between life-style behaviors and social, environmental, medical and psychiatric variables. QoL, income, age and depressive symptoms were central in the multidimensional network. Physical health-related QoL seems to be a ‘bridge node’ connecting depressive symptoms with several life-style and health variables. Further studies should assess such interactions in the general population
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
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