1,706 research outputs found
TUTELA DEL LAVORO E LIBERTA' D'IMPRESA NEI PROCESSI DI ESTERNALIZZAZIONE
No full textL’elaborato analizza le conseguenze lavoristiche della successione fra imprenditori, muovendo da una ricognizione delle varie tipologie di esternalizzazione con le relative esigenze e principali criticità.
L’indagine si concentra in primo luogo sul trasferimento d’azienda, esaminando la normativa e la giurisprudenza europee per passare poi alla disciplina di diritto interno, alle procedure sindacali e a uno specifico focus sul trasferimento delle aziende in crisi.
Successivamente l’autore si sofferma sull’appalto, prendendone in particolare considerazione gli indici di genuinità, i criteri di distinzione dalla somministrazione illecita di manodopera e la tutela delle maestranze in caso di avvicendamento fra imprese.
Da ultimo, la ricerca approfondisce le c.d. “clausole sociali”, sia di prima che di seconda generazione, valutandone la compatibilità con il diritto eurounitario e con la costituzione nonché riflettendo sui possibili rimedi in caso di loro violazione.The author analyzes the labour consequences of the succession between entrepreneurs, starting from a recognition of the various types of outsourcing with the related needs and main critical issues.
The survey focuses primarily on the transfer of businesses, examining European legislation and case-law and then moving on to internal legislation, trade union procedures and a specific focus on the transfer of companies in crisis.
The author then dwells on the contract, taking into account in particular the indications of authenticity, the criteria of distinction from the illicit administration of labour and the protection of workers in the event of turnover between companies.
Finally, the research deepens the "social clauses", both first and second generation, assessing their compatibility with European law and with the constitution and reflecting on possible remedies in case of their violation
Analysis of AtGUS1 and AtGUS2 in Arabidopsis root apex by a highly sensitive TSA-MISH method
No full textA new highly sensitive whole-mount in situ hybridization method, based on tyramide signal amplification (TSA-MISH) was developed and a combined GFP detection and TSA-MISH procedure was applied for the first time in plants, to precisely define the spatial pattern of AtGUS1 and AtGUS2 expression in the root apex. β-glucuronidases (GUSs) belonging to the glycosyl hydrolases (GHs) 79 family, are widely distributed in plants, but their functional role has not yet been fully investigated. In the model system Arabidopsis Thaliana, three different AtGUS genes have been identified which encode proteins with putative different fates. Endogenous GUS expression has been detected in different organs and tissues, but the cyto-histological domains of gene expression remain unclear. The results here reported show co-expression of AtGUS1 and AtGUS2 in different functional zones of the root apex (the cap central zone, the root cap meristem, the staminal cell niche and the cortical cell layers of the proximal meristem), while AtGUS2 is exclusively expressed in the cap peripheral layer and in the epidermis in the elongation zone. Interestingly, both genes are not expressed in the stelar portion of the proximal meristem. A spatial (cortex vs. stele) and temporal (proximal meristem vs. transition zone) regulation of AtGUS1 and AtGUS2 expression is therefore active in the root apex. This expression pattern, although globally consistent with the involvement of GUS activity in both cell proliferation and elongation, clearly indicates that AtGUS1 and AtGUS2 could control distinct downstream process depending on the developmental context and the interaction with other players of root growth control. In the future, the newly developed approaches may well be very useful to dissect such interactions
Primary MiNEN of the urinary bladder: an hitherto undescribed entity composed of large cell neuroendocrine carcinoma and adenocarcinoma with a distinct clinical behavior : Description of a case and review of the pertinent literature
No full textNeuroendocrine carcinomas (NECs) of the urinary bladder are very rare and can be observed in the context of mixed neuroendocrine/non-neuroendocrine neoplasms (MiNENs), most frequently in association with urothelial carcinoma. Small cell NECs are far more common than large cell NECs (LCNECs), which are exceedingly rare. We describe a primary MiNEN of the urinary bladder, composed of a LCNEC and of an adenocarcinoma, in which the neuroendocrine component reached complete pathological regression after neoadjuvant M-VAC chemotherapy, whereas the non-neuroendocrine component of the tumor progressed to metastatic disease. Compared to mixed neuroendocrine/non-neuroendocrine neoplasms described in the literature until now, this appears to be a unique case that expands the spectrum of neuroendocrine neoplasia of the urinary bladder
Ultra Low Carbon Vehicles: New Parameters for Automotive Design
No full textAs the influence of vehicle emissions on our environment has become better understood, the UK government has recently placed urgent emphasis on the implementation of low carbon
technologies in the automotive industry through: the UK Low Carbon Industrial Strategy. The overall objective is to offer big incentives to consumers and support for the development of infrastructure and engineering solutions. This scheme however does not consider how the development of functional and experiential user value might drive consumer demand, contributing to the adoption of low carbon vehicles (LCVs) in the mass market.
With the emergence of the North East of England as the UK’s first specialised region for the development of ultra-low carbon vehicles (ULCVs), ONE North East, as a development agency for the region's economic and business development, and Northumbria University Ideas-lab have supported a project to facilitate innovation through the collaboration of technology, research and development (R&D) and business. The High Value Low Carbon (HVLC) project aims to envisage
new user value made possible by the integration of low carbon vehicle platforms with new process and network technologies. The HVLC consortium represents vehicle manufacturers and their suppliers as well as technology based companies and through an ongoing process of design concept generation the project offers a hub for innovation led enterprise.
Whilst new technological developments in areas such as power generation, nano materials, hydrogen fuel cells, printed electronics and networked communications will all impact on future automotive design, the mass adoption of low carbon technologies represents a paradigm shift for the motorist. This paper aims to describe how the mapping of new parameters will lead to new transport scenarios that will create the space for new collaborative research on user experiences supported by innovative technologies and related services
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Matteo Maria Boiardo (1441-1494)
No full textMatteo Maria Boiardo – contemporary of Sir Thomas Malory and forerunner of Shakespeare, Spenser, Milton, Cervantes, Tolkien, and C.S. Lewis – is best known as the author of the Orlando Innamorato [Orlando in Love], a poem in ottava rima organically merging Carolingian epic and Arthurian romance. He was also a lyric and pastoral poet, playwright, and translator of classical texts into the Italian vernacular. Matteo was active in Italy during the years of 1463 throughout 1494, the year of his death
Uno sguardo all'Est. Lavoro e diritti fondamentali in Russia e negli altri Paesi della Comunità di Stati indipendenti
No full textNel contributo l'autore, dopo aver esaminato i diritti fondamentali del lavoro presenti nelle Costituzioni dei Paesi della Comunità di Stati indipendenti, si sofferma sul diritto del lavoro russo. La trattazione, a carattere diacronico, abbraccia i rami principali del diritto del lavoro: il rapporto individuale, le relazioni collettive, il mercato del lavoro. L'autore rileva una sorprendente continuità nelle linee essenziali del diritto del lavoro russo, pur nel susseguirsi di sistemi socioeconomici completamente diversi. Egli conclude che il diritto del lavoro russo appartiene saldamente alla matrice europea della materia.The contribution of the author starts by examining fundamental labour rights recognised by the Constitutions of the Countries of the Community of Independent States. Then the author focuses upon Russian Labour Law, going through the history of the main branches of the discipline: the individual relationship, industrial relations, the labour market. The article finds a surprising continuity in the essential lines of Russian Labour Law, in spite of the completely different socio-economic systems that were experimented in Russia during the twentieth century. The author concludes that Russian Labour Law clearly belongs to the European matrix of the discipline
Corpo, spazio, architettura. Fenomenologia dell’esperienza spaziale Matteo Vegetti, Fabrizia Bandi (eds.), Editrice Morcelliana, Brescia 2024
No full textThe author reviews "Corpo, spazio, architettura: Fenomenologia dell’esperienza spaziale," edited by Matteo Vegetti and Fabrizia Bandi. The book examines the philosophical underpinnings of spatial experience through a phenomenological lens, engaging with both traditional and contemporary notions of how space, body, and architecture interconnect. The author highlights the text\u27s exploration of how architects and designers might integrate phenomenological insights into their work, transforming space from mere physical dimensions into lived, experienced reality. The review appreciates the book’s thematic organization, which starts with foundational theories from Merleau-Ponty and expands through discussions on virtual spaces and the future of architecture in the digital age. Through this anthology, readers gain a comprehensive view of the architectural implications of phenomenological thought, making it a critical resource for anyone involved in the conceptualization and design of space
Espressione dei geni GUS e UGT85A in Arabidopsis thaliana
No full textLe β-glucuronidasi (GUS) sono enzimi che catalizzano l’idrolisi del legame glicosidico fra l’acido β-glucuronico e altre molecole e sono suddivise in due famiglie: glicosil-idrolasi 2 e glicosil-idrolasi 79. Le β-glucuronidasi della famiglia 2, alle quali appartiene il GUS di E. coli largamente usato come gene reporter nei vegetali, sono note in un grande range di organismi, ma sembrano essere assenti nelle piante, nelle quali l’attività GUS endogena sembra associata a β-glucuronidasi della famiglia 79 (Eparanasi) (1).
In Arabidpopsis thaliana sono stati identificati e parzialmente caratterizzati tre diversi geni GUS (AtGUS1, AtGUS2 e AtGUS3), dei quali AtGUS1 e AtGUS2 mostrano elevata omologia.
A parte funzioni specifiche (2),coinvolgimento delle β-glucuronidasi è stato proposto nel processo di accrescimento cellulare per distensione e, in particolare, nell’allungamento dei peli radicali (3). E’ stato, inoltre, ipotizzato che β-glucuronidasi, agendo in coordinazione con glucuronisiltrasferasi (UGT) del gruppo 85A, siano responsabili della regolazione del ciclo cellulare (4,5). Uno studio più recente tuttavia ha messo in parte in discussione quanto emerso in precedenza riportando che nelle radici di plantule di Arabidopsis thaliana non è presente attività β-glucuronidasica (6).
In questo lavoro si è voluto approfondire lo studio dell’espressione dei geni GUS e UGT in Arabidopsis. Verifiche preliminari effettuate con PCR semiquantitativa hanno mostrato che, nonostante il gene AtGUS2 risulti espresso in modo più rilevante rispetto a AtGUS1 e AtGUS3, tutti e tre i geni AtGUS sono espressi, sia pure differenzialmente, in tutti gli organi della pianta. I geni AtUGT85A mostranoun pattern di espressione più differenziato rispetto ai geni AtGUS. AtUGT85A1, AtUGT85A2 e AtUGT85A4 risultano differenzialmente espressi nei vari organi della pianta, mentre AtUGT85A3 e UGT85A7 mostrano un’espressione organo specifica che coinvolge fiore e foglia
Utilizzando la tecnica di ibridazione in situ con sonde multiple recentemente messa a punto su campioni vegetali (7), l’espressione dei geni GUS è stata studiata anche a livello tissutale. A livello radicale , il pattern di espressione dei tre geni analizzati appare chiaramente differenziato: AtGUS1 e AtGUS2 sono espressi nell’epidermide, nella zona corticale e nella cuffia, mentre l’espressione di AtGUS3 è limitata all’epidermide. Sono in corso le analisi relative agli altri organi della pianta e, in particolare, fiore e polline. Analogo approccio verrà esteso ai geni AtUGT85 al fine di verificarne l’overlapping o meno con i domini istologici di espressione dei geni GUS e definirne eventuali correlazioni
Elenco delle abbreviazioni
No full textAntico Testamento Gen. = Genesi Es. = Esodo Lev. = Levitico Dt. = Deuteronomio Is. = Isaia Gb. = Giobbe Nuovo Testamento Mt. = Matteo (ca. 90 d.C.) Mc. = Marco (ca. 70 d.C.) Lc. = Luca (ca. 100 d.C.) Gv. = Giovanni (ca. 110 d.C.) At. = Atti degli apostoli Lettere di Paolo Rm. = Lettera ai Romani (53-54 d.C.) 1 Cor. = Prima lettera ai Corinti (ca. 51 d.C.) 2 Cor. = Seconda lettera ai Corinti (ca. 52 d.C.) Gal. = Lettera ai Galati (ca. 52 d.C.) Fil. = Lettera ai Filippesi (ca. 51-52 o 57 d.C.
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