1,720,970 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Estudio de las mutaciones de los genes c-kit y pdgfra y la expresión de mirnas en una serie de tumores estromales del tracto gastrointestinal (gist) de la cspt. Correlación entre los hallazgos moleculares y la evolución clínica
Get PDFLos tumores estromales del tracto gastrointestinal (GISTs) son las neoplasias estromales más frecuentes en esta localización. Expresan c-kit (CD117) y CD34 de forma característica. Los GIST presentan mutaciones ("gain-of-function") en uno de los dos genes de receptores tirosinquinasa (c-KIT y PDGFRA), aunque en el 10% no se detectan mutaciones (GIST "wild-type"). En los GISTs, destaca la implicación de los microRNA-221, 222 y 494. Estos microRNA se unen al mRNA del gen c-KIT y su infraregulación implica un aumento de expresión proteica de c-kit. Los objetivos planteados en este estudio son los siguientes, aplicados a una serie de casos de GIST estudiados en Parc Taulí Sabadell Hospital Universitari: determinar la asociación entre parámetros clínico-patológicos, inmunohistoquímicos e índice de proliferación celular Ki-67; determinar las mutaciones de los genes c-KIT y PDGFRA y niveles de expresión de miRNA-221, 222 y 494 y correlacionar con los grupos de riesgo pronóstico (criterios AFIP-Miettinen 2006), parámetros clínico-patológicos e inmunohistoquímicos y progresión tumoral; establecer un patrón molecular diferencial entre los diferentes grupos de riesgo y aplicar y determinar el "nomograma" del SKCC para predecir la probabilidad de supervivencia libre de recurrencia a los 2 y 5 años y comparar con las probabilidades observadas. Las conclusiones obtenidas en nuestro estudio son las siguientes: La presencia de necrosis, positividad de intensidad marcada (3+) para c-kit, positividad para c-kit con patrón de Golgi, expresión elevada de Ki-67 y elevada tendencia a presentar metástasis, se asocian con más frecuencia a GISTs del grupo de alto riego. Los GISTs con morfología fusocelular y mixta se asocian a peor comportamiento biológico que los GISTs con morfología epitelioide. La mutación en el exón 11 se asocia con más frecuencia a pacientes de edad más avanzada, mujeres, localización en intestino delgado, morfología fusocelular y positividad con intensidad marcada (3+) para c-kit. Los tipos de mutación deleción/indel tienen más tendencia a distribuirse en GISTs localizados en intestino delgado, de alto riesgo y muestran menor supervivencia global que los GISTs con mutaciones puntuales. La mutación en el exón 9 se asocia con más frecuencia a GISTs localizados en intestino delgado, de morfología de tipo mixto y con valores de expresión de Ki-67 elevados. Los casos con mutación en el exón 9 de c-KIT y en el 18 de PDGFRA tienen más tendencia a expresar CD34 que el resto de mutaciones. La mutación en el exón 18 se asocia con más frecuencia a sexo masculino, localización gástrica, morfología epitelioide, matriz mixoide y grupo de muy bajo riesgo. Los GISTs wild-type se localizan con más frecuencia en estómago, presentan morfología fusocelular y vacuolización citoplasmática. En relación a los niveles de expresión de miRNAs: la mayoría de casos presentan niveles de expresión inferiores a 1. Diferencias de expresión en los distintos miRNAs se han asociado a parámetros clínico-patológicos y evolutivos como: localización, positividad para CD34, grupos de riesgo, tipo histológico, intensidad y patrón de c-kit y supervivencia específica. Todos los casos de GISTs wild-type de nuestra serie han mostrado niveles de expresión de miRNAs inferiores a 0,7. Aplicado el nomograma se observa que las predicciones tienden a cumplirse en los casos con alta probabilidad de supervivencia libre de recurrencia a los 2 años (80-100%), aunque no se demuestran diferencias estadísticamente significativas.Gastrointestinal stromal tumors (GISTs) are the most common stromal malignancies in this location. GISTs express c-kit (CD117) and CD34 characteristically. Mutations (gain-of-function) are detected in one of two receptor tyrosine kinase genes (c-KIT and PDGFRA), although in 10% of GISTs mutations are not detected (GIST "wild-type"). In these tumors, involvement of microRNA-221, 222 and 494 has been described. These miRNAs bind to mRNA of c-KIT gene and its downregulation implies increased expression of c-kit protein. The aims of this study, applied in a series of GIST cases studied in Parc Taulí Sabadell Hospital Universitari, are: to determine the association between clinicopathological and immunohistochemical parameters and cell proliferation index (Ki-67); to determine the mutations of c-KIT and PDGFRA genes and expression levels of miRNA-221, 222 and 494 and correlate with prognostic risk groups (criteria AFIP-Miettinen 2006), clinicopathological and immunohistochemical parameters, and tumor progression; to establish a differential molecular signature between different risk groups; and to determine the "nomogram" of the SKCC for predicting the probability of recurrence-free survival at 2 and 5 years and compare with the observed probabilities. Conclusions obtained from our study are: Presence of necrosis, strong intensity (3+) for c-kit, c-kit-positive Golgi pattern, high expression of Ki-67 and high tendency to metastasize, are most often associated with GISTs of high-risk group than the other risk groups. GISTs with spindle and mixed cell morphology are associated with worse biological behaviour than GISTs with epithelioid morphology. Mutation in exon 11 is most often associated with older patients, women, small bowel localization, spindle cell morphology and strong intensity (3 +) for c-kit. Delection/indel types of mutation are more likely to be distributed in GISTs located in small bowel and high-risk group, and show lower overall survival that GISTs with punctual mutations. Mutation in exon 9 is more often associated with small bowel location, mixed morphology and high expression values of Ki-67. GIST with mutation in exon 9 of c-KIT and exon 18 of PDGFRA are more likely to express CD34 than other mutations. Mutation in exon 18 is more often associated with male gender, gastric location, epithelioid morphology, myxoid matrix and very low-risk group. The wild-type GISTs are found more often in stomach, with spindle cell morphology and cytoplasmic vacuolization. In relation with the expression levels of miRNAs, most cases present expression levels below 1. Differences in expression of the different miRNAs have been associated with some clinicopathological and biological behaviour parameters as: location, CD34 positivity, risk groups, histological type, intensity and pattern of c-kit and specific survival. All cases of wild-type GISTs in our series have shown miRNAs expression levels less than 0.7. When applying the nomogram, predictions and real values tend to coincide in cases with high probability of recurrence-free survival at 2 years (80-100%), although no statistically significant differences were found
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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