6 research outputs found
Te Utu
No full textWhangape, 1528, ko Korekore te whiwhia te maramataka.
Taiao and his army went hunting for birds and set snares. While they were there, Taiao saw the gutless pig, who killed his father twelve years ago. After Taiao saw Te Pō in the distance, he instructed his troops with his taiaha to stop and be stealthy. Taiao crouched under the cover of the bushes and watched, stalking Te Pō and his small ope.
While watching Te Pō, Taiao had intermittent, yet vivid flashbacks of the night his papa kāinga was attacked by Te Pō and his troops, 12 years ago. 
Jacob Shatzky 1912-ca.1960
No full textCorrespondence with Jewish literary, cultural and political figures, and communal leaders, including Ber Borochov, Boris Thomashefsky, Solomon Grayzel, Aaron Glanz-Leieles, H. Leivick, Joseph Opatoshu, Isaac Bashevis Singer, Menahem Boraisha, Shmuel Niger, Kalman Marmor, Mark Wischnitzer, Max Weinreich, Emanuel Ringelblum. Correspondence with organizations, societies, publishers. Family correspondence. Notes and photostatic copies for Shatzky's book, *History of the Jews in Warsaw*, Volumes I-III, New York, 1947-1953 and Volume IV which is unpublished. Topics relate to: the rabbinate; community council; local organizations; Yiddish literature, art and culture; education; industry, trade, banks; political movements; charities. An abbreviated unpublished version of *A History of the Jews in Warsaw*. Notes, manuscripts and correspondence relating to the *Shatzky bukh* (The Shatzky Book), ed. E. Lifschutz, YIVO, 1957. Clippings of Shatzky's writings, as well as reviews and articles about Shatzky, 1910s-1960s. Manuscripts and notes for articles by Shatzky on topics in Jewish history, Yiddish folklore and literature. Materials, including biographical sketches, for the *Leksikon fun der nayer Yidisher literatur*. Materials relating to Shatzky's biographical work *Moris rozenfeld, in likht fun zayne briv* (Morris Rosenfeld, in the light of his letters), New York, 1936. Bibliographies, on cards relating to: early Yiddish literature in print; topics of medical interest in Jewish history; Judaica; theatralia; psychiatry and Jews; American Jewish press. Personal documents. Posters and lecture announcements.Historian, writer, lecturer, lexicographer, bibliographer, editor. One of the founders of "Amopteyl", the American branch of YIVO. Member of the Board of Directors of YIVO. Co-editor of the YIVO bleter and the YIVO Annual of Social Science. Co-editor of the *Leksikon fun der nayer yidisher literatur* (*Biographical Dictionary of Modern Yiddish Literature*), N.Y., 1956. President, Yiddish Pen Club. Director, Research Library of the New York State Psychiatric Institute. Wrote numerous works on Jewish history, concentrating on the history of the Jews in Poland. Co-author, with Leland E. Hinsie, of the *Psyhciatric Dictionary*. Born in Warsaw, Poland. Immigrated to the U.S. in 1923.Inventory: English, 52 pp., typedMARC2EAD YIVO PILOT INGEST BATCH
Jacob Shatzky 1912-ca.1960
No full textCorrespondence with Jewish literary, cultural and political figures, and communal leaders, including Ber Borochov, Boris Thomashefsky, Solomon Grayzel, Aaron Glanz-Leieles, H. Leivick, Joseph Opatoshu, Isaac Bashevis Singer, Menahem Boraisha, Shmuel Niger, Kalman Marmor, Mark Wischnitzer, Max Weinreich, Emanuel Ringelblum. Correspondence with organizations, societies, publishers. Family correspondence. Notes and photostatic copies for Shatzky's book, *History of the Jews in Warsaw*, Volumes I-III, New York, 1947-1953 and Volume IV which is unpublished. Topics relate to: the rabbinate; community council; local organizations; Yiddish literature, art and culture; education; industry, trade, banks; political movements; charities. An abbreviated unpublished version of *A History of the Jews in Warsaw*. Notes, manuscripts and correspondence relating to the *Shatzky bukh* (The Shatzky Book), ed. E. Lifschutz, YIVO, 1957. Clippings of Shatzky's writings, as well as reviews and articles about Shatzky, 1910s-1960s. Manuscripts and notes for articles by Shatzky on topics in Jewish history, Yiddish folklore and literature. Materials, including biographical sketches, for the *Leksikon fun der nayer Yidisher literatur*. Materials relating to Shatzky's biographical work *Moris rozenfeld, in likht fun zayne briv* (Morris Rosenfeld, in the light of his letters), New York, 1936. Bibliographies, on cards relating to: early Yiddish literature in print; topics of medical interest in Jewish history; Judaica; theatralia; psychiatry and Jews; American Jewish press. Personal documents. Posters and lecture announcements.Inventory: English, 52 pp., typedHistorian, writer, lecturer, lexicographer, bibliographer, editor. One of the founders of "Amopteyl", the American branch of YIVO. Member of the Board of Directors of YIVO. Co-editor of the YIVO bleter and the YIVO Annual of Social Science. Co-editor of the *Leksikon fun der nayer yidisher literatur* (*Biographical Dictionary of Modern Yiddish Literature*), N.Y., 1956. President, Yiddish Pen Club. Director, Research Library of the New York State Psychiatric Institute. Wrote numerous works on Jewish history, concentrating on the history of the Jews in Poland. Co-author, with Leland E. Hinsie, of the *Psyhciatric Dictionary*. Born in Warsaw, Poland. Immigrated to the U.S. in 1923
Divergent clonal selection dominates medulloblastoma at recurrence
No full textThe development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. We treated a transposon-driven, functional genomic mouse model of medulloblastoma with 'humanized' in vivo therapy (microneurosurgical tumour resection followed by multi-fractionated, image-guided radiotherapy). Genetic events in recurrent murine medulloblastoma exhibit a very poor overlap with those in matched murine diagnostic samples (<5%). Whole-genome sequencing of 33 pairs of human diagnostic and post-therapy medulloblastomas demonstrated substantial genetic divergence of the dominant clone after therapy (<12% diagnostic events were retained at recurrence). In both mice and humans, the dominant clone at recurrence arose through clonal selection of a pre-existing minor clone present at diagnosis. Targeted therapy is unlikely to be effective in the absence of the target, therefore our results offer a simple, proximal, and remediable explanation for the failure of prior clinical trials of targeted therapy
Divergent clonal selection dominates medulloblastoma at recurrence
No full textThe development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. We treated a transposon-driven, functional genomic mouse model of medulloblastoma with \u27humanized\u27 in vivo therapy (microneurosurgical tumour resection followed by multi-fractionated, image-guided radiotherapy). Genetic events in recurrent murine medulloblastoma exhibit a very poor overlap with those in matched murine diagnostic samples (<5%). Whole-genome sequencing of 33 pairs of human diagnostic and post-therapy medulloblastomas demonstrated substantial genetic divergence of the dominant clone after therapy (<12% diagnostic events were retained at recurrence). In both mice and humans, the dominant clone at recurrence arose through clonal selection of a pre-existing minor clone present at diagnosis. Targeted therapy is unlikely to be effective in the absence of the target, therefore our results offer a simple, proximal, and remediable explanation for the failure of prior clinical trials of targeted therapy
Depresión en padres y cuidadores de personas con trastorno del espectro autista : revisión sistematizada
No full text85 páginasPara poner en contexto, en el mundo se considera que el 1% de la población padece alguna forma del trastorno del espectro autista, esto no puede dar una idea de la cantidad de familias que deben convivir con personas con TEA, generalmente son los padres o hermanos quienes frecuentemente interrumpen aspectos de su vida diaria o sus proyectos de vida, tales como relaciones sociales y/o trabajo entre otros, esto, para satisfacer las necesidades del individuo con trastorno del espectro autista.
La responsabilidad, el desconocimiento al enfrentar este síndrome, el saber que qué esta condición en su ser querido será permanente, desencadena un sin número factores, que terminan por afectar la vida y generan una cadena de estrés que resulta en un estado de vulnerabilidad para los padres hacia el desarrollo de depresión. La depresión constituye un trastorno de salud mental que tiene un impacto en la vida de una persona y de su familia en particular cuando se presenta en los padres de un individuo con autismo, el identificar síntomas depresivos en los padres, puede mejorar su salud y puede ayudar con el pronóstico de sus hijos. En la actualidad la mayoría de intervenciones existentes se enfocan solamente en el individuo con Trastorno del espectro autista, por lo que se debería concientizar a la comunidad de la salud sobre la depresión en esta población y se debe identificar como un problema que está interfiriendo con el buen desarrollo de los individuosTo put into context, in the world it is considered that 1% of the population suffers from some form of autistic spectrum disorder, this can’t give an idea of the number of families that must live with people with TEA, usually parents or siblings who frequently interrupt aspects of their daily life or their life projects, such as social relationships and / or work among others, this, to meet the needs of the individual with autism spectrum disorder. The responsibility, the ignorance in facing this syndrome, the knowledge that what this condition in your loved one will be permanent, unleashes a number of factors, which end up affecting life and generate a chain of stress that results in a state of vulnerability for the parents towards the development of depression. Depression is a mental health disorder that has an impact on the life of a person and their family in particular when it occurs in the parents of an individual with autism, identifying depressive symptoms in parents, can improve their health and can help with the prognosis of their children.Currently most of the existing interventions focus only on the individual with Autism Spectrum Disorder, so the health community should be made aware of depression in this population and should be identified as a problem that is interfering with the good development ofIncluye bibliografíaPregradoMédico(a) Cirujan
