883 research outputs found
simresist
No full text<p>This open-source R package was developed for and is described in the paper "Predicting the risk and speed of drug resistance emerging in soil-transmitted helminths during preventive chemotherapy" by Coffeng et al. See Appendix A of the paper for the operating system and version numbers of the software and R packages that simresist was tested with.</p>
<p>The associated live Gitlab repository can be found at: https://gitlab.com/luccoffeng/simresist</p>
Predicting the risk and speed of drug resistance emerging in soil-transmitted helminths during preventive chemotherapy
No full textData that support the findings of the paper "Predicting the risk and speed of drug resistance emerging in soil-transmitted helminths during preventive chemotherapy" by Luc E. Coffeng, Wilma A. Stolk, and Sake J. de Vlas. Data were simulated with the R package simresist v1.1.1 (https://gitlab.com/luccoffeng/simresist; frozen version used to generate these files can be found at https://doi.org/10.5281/zenodo.10442358). Code to reproduce these simulated data can be found here: https://gitlab.com/luccoffeng/simresist-nature-comms-sth-paper
Authorship in the Interstices of History, Biography, Reality and Memory: Histoire(s) du cinéma and Cabra Marcado para Morrer
Full text linkEste artigo contrasta Histoire(s) du cinéma de Jean-Luc Godard e Cabra Marcado Para Morrer de Eduardo Coutinho, estão engajadas com a questão da autoria no cinema. Enquanto a imagem de Godard enfatiza a capacidade que tem um filme de transmitir a visão de mundo pessoal de um artista, a presença de Coutinho na tela funciona menos como um meio de subjetivar a obra do que como um catalizador instigando cetas reações nos "atores" filmados
The economic burden of visceral leishmaniasis and barriers to accessing healthcare in Tigray, North Ethiopia: A field based study
Full text linkBackground: Visceral leishmaniasis (VL) is an important public health problem, which mainly affects the poor rural dwelling communities in Low- and Middle-Income Countries. However, little is known about the health and economic burdens of this disease in East Africa, including Ethiopia. The aim of this study was to assess the household level economic burden of VL among affected communities in Tigray, Northern Ethiopia. Methods: Between April and August 2020, a cross-sectional household survey was conducted on 96 patients who had been treated for VL within 12 months prior to the survey, in six districts of Tigray. Data on households’ health seeking behavior, direct and indirect costs and coping strategies were collected using a structured questionnaire and the responses were analyzed using SPSS software. Results: Most (82%) of the patients surveyed were males and the majority (74%) of them were between 16 and 30 years of age. The education level of participants was very low: over 33% had not received any form of education; 48% of patients were farmers dependent on subsistence agriculture and about 32% were daily laborers. Just under half of household families (46%) resided in “poor houses” with structures made from entirely local materials. Forty-one percent of patients from the surveyed households had traveled 48 to 72 kilometers to reach VL treatment hospitals. The median total household cost for one VL episode was estimated to be US$ 214. This is equated to 18% of the mean total annual household income or 72.5% of annual per capita income of the study population. More than 80% of the households surveyed incurred catastrophic costs of VL, where this is defined as exceeding 10% of annual household income. The median delay between the onset of symptoms and arrival at a care provider hospital was 37 days; once the patient arrived at hospital, the median delay during diagnosis was 3 days. Direct and indirect costs represented 44% and 56% of the total costs incurred, respectively. To cope with VL treatment costs, 43% of the households used more than one coping strategy: 48% took out loans, 43% sold livestock and 31% of households mobilized cash savings. Conclusions: VL in Tigray is concentrated among young males with low educational background and mostly engaged in subsistence economic activities. Despite the free diagnostic and treatment provisions that were available at public hospitals at the time of the study, our work shows that the household economic burden of the disease had significant impact among VL-affected communities in Tigray. Initiating community awareness towards prevention, early treatment seeking and decentralization of VL treatment centers are strongly recommended. In addition, we recommend efforts to reduce household treatment costs through transport and food provisions for patients (and their accompanying carers where possible) or through cash reimbursement for patients who complete treatment at public hospitals, in order to reduce the barriers to seeking treatment for this life-threatening disease
A Canonical Form for PROV Documents: Dataset Underpinning Evaluation
No full textDataset supporting:
Luc Moreau (2017) A Canonical Form for PROV Documents and its Application to Equality, Signature, and Validation. ACM Transactions on Internet Technology.
We present a canonical form for PROV that is a normalized way of representing PROV documents as mathematical expressions. As opposed to the normal form specified by the PROV-CONSTRAINTS recommendation, the canonical form we present is defined for all PROV documents, irrespective of their validity, and it can be serialized in a unique way. The paper makes the case for a canonical form for PROV and its potential uses, namely: comparison of PROV documents in different formats, validation, and signature of PROV documents. A signature of a PROV document allows the integrity and the author of provenance to be ascertained; since the signature is based on the canonical form, these checks are not tied to a particular encoding, but can be performed on any representation of PROV.</span
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Provenance-based trust for grid computing: Position Paper
No full textCurrent evolutions of Internet technology such as Web Services, ebXML, peer-to-peer and Grid computing all point to the development of large-scale open networks of diverse computing systems interacting with one another to perform tasks. Grid systems (and Web Services) are exemplary in this respect and are perhaps some of the first large-scale open computing systems to see widespread use - making them an important testing ground for problems in trust management which are likely to arise. From this perspective, today's grid architectures suffer from limitations, such as lack of a mechanism to trace results and lack of infrastructure to build up trust networks. These are important concerns in open grids, in which "community resources" are owned and managed by multiple stakeholders, and are dynamically organised in virtual organisations. Provenance enables users to trace how a particular result has been arrived at by identifying the individual services and the aggregation of services that produced such a particular output. Against this background, we present a research agenda to design, conceive and implement an industrial-strength open provenance architecture for grid systems. We motivate its use with three complex grid applications, namely aerospace engineering, organ transplant management and bioinformatics. Industrial-strength provenance support includes a scalable and secure architecture, an open proposal for standardising the protocols and data structures, a set of tools for configuring and using the provenance architecture, an open source reference implementation, and a deployment and validation in industrial context. The provision of such facilities will enrich grid capabilities by including new functionalities required for solving complex problems such as provenance data to provide complete audit trails of process execution and third-party analysis and auditing. As a result, we anticipate that a larger uptake of grid technology is likely to occur, since unprecedented possibilities will be offered to users and will give them a competitive edge
Luc: Estang: Trilogist
No full textThe original purpose of this thesis was to make a critical study of Luc Estang and his position among contemporary Catholic novelists, as seen through his trilogy, Charges d\u27ames. To date, les Stigmates and Cherchant qui devorer have been published. Originally the third novel of the trilogy was to come out in the first few months of this year. However, for commercial reasons, the publication of les Fontaines d\u27abime has been delayed until the spring of 1954. This necessitates a slight change in the province of this thesis. It will be an expository study of les Stigmates and Cherchant qui devorer. For the plots, characters, style, setting and documentation, only these two works will be considered. For the chapter on thought, other works by the same author and also works of such novelists as Mauriac, Bernanos, Greene and Wagh will be used to supplement the two works studied. This analysis inspires many questions but not the final answers. The author of this essay hopes that Luc Estang\u27s relationship to and his place among the authors of the Catholic Revival have been appraised to a degree that will prove enlightening
L'Encomio di Sant'Anastasio di Giorgio di Pisidia Studi filologici e letterari sulla prosa filosofico-agiografica greca tardoantica (V-VII sec. d.C.)
No full textThe aim of the thesis is to understand the purpose of an hagiographic discourse, basing the analysis on the tradition, the author, the style and the public of certain texts.
These texts (exemplified by the Encomium of Saint Anastasius by George of Pisidia), were written in Greek prose during the period of Late Antiquity and Early Byzantium.
Their authors increasingly tended to follow the precepts of rhetoric and to rework the canons of hagiographic literature.
The thesis is divided into five chapters.
The first traces the history of rewriting and shows the evolution of the paraphrastic technique between the sixth and seventh centuries AD. The analysis extends up to the seventy Miracles of Cyrus and John by Sophronius of Jerusalem and to the Encomium of Saint Anastasius by George of Pisidia, a metaphrase of the acts of martyrdom, whose aim was to propagate the victories of the Christian Empire against Persia.
From the second chapter, the attention is focused only on the Encomium, of which is offered an Italian translation.
The third chapter is a discussion on the spread of the cult of Saint Anastasius, after his martyrdom on January 22, 628 AD.
The fourth chapter focuses on the technique used by George to rewrite the acts of the martyrdom of Saint Anastasius.
The last chapter analyzes the structure of the Encomium, trying to highlight the points where the prose of George seems to follow more closely the dictates of late antique rhetoric.
It is hoped with this to emphasize the importance of a text as the Encomium, within the panegyric production of George of Pisidia, but also the literary history of the seventh century AD and, more generally, of Late Antiquity.L'obiettivo della tesi è mostrare come sia possibile comprendere la finalità di un discorso agiografico a partire dallʼanalisi della sua tradizione, del suo autore e soprattutto della sua componente stilistica, un dato, questʼultimo, in grado di dire molto sul pubblico cui certi testi erano indirizzati.
Sono stati infatti presi in esame soltanto quei testi di prosa greca ed agiografica tardoantica e protobizantina (esemplificati, nel corso del lavoro, dallʼEncomio di SantʼAnastasio di Giorgio di Pisidia), che sempre più tendevano ad adagiarsi su un fondo comune offerto dalla precettistica retorica, unico punto fermo per comprendere tanto labor limae nellʼopera di autori che iniziavano anche a rielaborare, secondo il gusto delle singole epoche, la letteratura agiografica canonica.
La tesi si articola in cinque capitoli.
Il primo ripercorre la storia del processo di riscrittura tra il VI ed il VII secolo d.C. Obiettivo è quello di mostrare lʼevoluzione della tecnica parafrastica tra Occidente ed Oriente. Lʼanalisi si estende fino ai settanta Miracoli di Ciro e Giovanni di Sofronio di Gerusalemme, composti verso la metà del VII secolo d.C. dal campione dellʼortodossia contro il dilagare della crisi monotelita, e lʼEncomio di SantʼAnastasio di Giorgio di Pisidia, metafrasi degli Atti del martirio operata dal poeta della corte eracliana e finalizzata a propagandare le vittorie dellʼimpero cristiano contro la Persia.
A partire dal secondo capitolo, lʼattenzione si concentra sul solo Encomio pisidiano, di cui viene offerta la prima traduzione in lingua italiana.
Il terzo capitolo è una disamina sulla nascita e la diffusione del culto di SantʼAnastasio, dopo il suo martirio a Bethsaloé dʼAssiria il 22 gennaio del 628 d.C.
Il quarto capitolo prende in esame la tecnica di riscrittura degli Atti del martirio di SantʼAnastasio da parte di Giorgio.
Lʼultimo capitolo analizza la struttura dellʼEncomio, cercando di mettere in rilievo i punti in cui la prosa di Giorgio sembra seguire più attentamente i dettami della retorica tardoantica.
Si spera con ciò di riuscire a sottolineare la rilevanza di un testo come lʼEncomio di SantʼAnastasio, allʼinterno della produzione panegiristica di Giorgio di Pisidia, ma anche della storia letteraria del VII secolo d.C. e, più in generale, della Tarda Antichità.Lʼobjectif de la thèse est de comprendre le but dʼun discours hagiographique, en fondant lʼanalyse sur la tradition, lʼauteur, le style et le public de certains textes.
Ces textes (illustrés par lʼÉloge de Saint Anastase par Georges de Pisidie), ont été écrits en prose grecque pendant la période de lʼAntiquité tardive et des premiers siècles de Byzance. Leurs auteurs suivaient les préceptes de la rhétorique et réélaboraient les canons de la littérature hagiographique.
La thèse est divisée en cinq chapitres.
Le premier trace une histoire de la réécriture et montre lʼévolution de la technique paraphrastique entre le sixième et septième siècle après J.-C. Lʼanalyse se prolonge jusquʼaux soixante-dix Miracles de Cyr et Jean par Sophrone de Jérusalem et à lʼÉloge de Saint Anastase par Georges de Pisidie, une métaphrase des actes du martyre, dont le but était de propager les victoires de lʼEmpire chrétien contre la Perse.
A partir du deuxième chapitre, lʼattention se concentre uniquement sur lʼÉloge, dont une traduction italienne est offerte.
Le troisième chapitre est une discussion sur la diffusion du culte de Saint Anastase, après son martyre, le 22 janvier 628 après J.-C.
Le quatrième chapitre se concentre sur la technique utilisée par Georges pour réécrire les actes du martyre de Saint Anastase.
Le dernier chapitre analyse la structure de lʼÉloge, en essayant de montrer les points où la prose de Georges suit les préceptes de la rhétorique ancienne tardive.
On espère de souligner lʼimportance de lʼÉloge dans la production panégyrique de Georges, mais aussi dans le contexte de lʼhistoire littéraire du septième siècle après J.-C. et, plus généralement, de lʼAntiquité tardive
Una mistica dell'adorazione? Jean-Luc Nancy
No full textCan we say that there is a "mystic" in the "adoration" revamped by Jean-Luc Nancy in his deconstruction of Christianity? Following this question the author traces a connection between deconstruction and mystic and between deconstruction and phenomenology. From the point of view Nancy's mystical vocation of "L'Adoration" can be summarized by the excess of meaning proper of every being insomuch as it is allowed to appear in its irrepressible distinction
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