196,683 research outputs found

    Non-parametric change point detection for spike trains

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    Mosqueiro T, Strube-Bloss M, Tuma R, Pinto R, Smith BH, Huerta R. Non-parametric change point detection for spike trains. In: 2016 Annual Conference on Information Science and Systems (CISS). Piscataway, NJ: IEEE; 2016

    CISS - a composite indicator of systemic stress in the financial system

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    This paper introduces a new indicator of contemporaneous stress in the financial system named Composite Indicator of Systemic Stress (CISS). Its specific statistical design is shaped according to standard definitions of systemic risk. The main methodological innovation of the CISS is the application of basic portfolio theory to the aggregation of five market-specific subindices created from a total of 15 individual financial stress measures. The aggregation accordingly takes into account the time-varying cross-correlations between the subindices. As a result, the CISS puts relatively more weight on situations in which stress prevails in several market segments at the same time, capturing the idea that financial stress is more systemic and thus more dangerous for the economy as a whole if financial instability spreads more widely across the whole financial system. Applied to euro area data, we determine within a threshold VAR model a systemic crisis-level of the CISS at which financial stress tends to depress real economic activity. Weekly updates of the CISS dataset at: sdw.ecb.europa.eu/browseSelection.do?node=955113

    Validez del cuestionario CISS-V15 para el diagnóstico de la insuficiencia de convergencia

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    Introduction: The Convergence Insufficiency Symptom Survey Questionnaire (CISS-V15) is a tool for diagnosis and monitoring of treatment of patients with convergence insufficiency. Objective: To determine the validity of the questionnaire CISS-V15 for the diagnosis of convergence insufficiency against clinical tests assessing the oculomotor state in optometric patients seen in consultation in the cities of Recife and Salvador, Brazil. Methods: A descriptive transversal study with a quantitative approach was conducted with 50 patients from two educational institutions in Brazil. Patients were selected from those that met the inclusion criteria for applying the questionnaire. Patients with convergence insufficiency and those with normal binocular vision were identified. The results of the questionnaire and ocular motility tests were analyzed to estimate central tendency measures and to analyze the sensitivity and specificity of the questionnaire. Results: The test had a sensitivity of 0.83 and a specificity of 0.81. Conclusions: Given the clinical test, the CISS-V15 questionnaire proved to be valid to classify individuals with convergence insufficiency, and those with normal binocular vision, which makes it a valuable tool for the diagnosis and monitoring of the treatment of patients with convergence insufficiency.Introducción. El cuestionario Convergence Insufficiency Symptoms Survey, (CISS-V15) es una herramienta para el diagnóstico y seguimiento del tratamiento de pacientes con insuficiencia de convergencia. Objetivo. Determinar la validez del cuestionario CISS-V15 para el diagnóstico de la insuficiencia de convergencia, frente a las pruebas clínicas con que se evalúa el estado motor ocular de los pacientes atendidos en consulta optométrica, en las ciudades de Recife y Salvador, Brasil. Métodos. Se llevó a cabo un estudio con enfoque cuantitativo, de tipo transversal y descriptivo, con 50 pacientes de dos instituciones educativas en Brasil. Se seleccionaron aquellos que cumplían con los criterios de inclusión para aplicar el cuestionario, y se identificaron los pacientes con insuficiencia de convergencia y aquellos con visión binocular normal. Se analizaron los resultados del cuestionario y las pruebas de motilidad ocular, para estimar medidas de tendencia central, y analizar los valores de sensibilidad y especificidad del cuestionario. Resultados. La prueba alcanzó una sensibilidad de 0,83 y una especificidad de 0,81. Conclusiones. Frente a las pruebas clínicas, el cuestionario CISS-V15 demostró tener validez diagnóstica para las personas con insuficiencia de convergencia y aquellas con visión binocular normal, lo que lo convierte en una herramienta valiosa para el diagnóstico y seguimiento del tratamiento de los pacientes con insuficiencia de convergencia. Palabras clave: trastornos de la motilidad ocular, visión binocular, astenopia, diplopía, validez de las pruebas

    Cold intolerance of the hand measure by the CISS questionnaire in a normative study population

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    Cold intolerance has been recognized as one of the most disabling sequelae of upper extremity trauma, especially when neurovascular structures are involved. In this study, we aimed to describe cold intolerance in a normative study population, validate the Cold Intolerance Symptom Severity (CISS) questionnaire and define the threshold for abnormal cold intolerance. One hundred and eight volunteers participated in our study. In addition to the CISS score, information about age, gender and previous surgery or trauma to the upper extremity was obtained. There were no volunteers with previous peripheral nerve injury and subjects with a history of Raynaud's disease, upper extremity injury or surgery were excluded (n = 40). The CISS scores of the study population (n = 68) averaged 12.9 (SD 8.2). Age and gender were not correlated with CISS score. The upper 95% confidence interval of the CISS scores for healthy subjects is about 30. We suggest this value as a threshold for pathological cold intolerance

    Developments in target micro-doppler signatures analysis: radar imaging, ultrasound and through-the-wall radar

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    Target motions, other than the main bulk translation of the target, induce Doppler modulations around the main Doppler shift that form what is commonly called a target micro-Doppler signature. Radar micro-Doppler signatures are generally both target and action speci c and hence can be used to classify and recognise targets as well as to identify possible threats. In recent years, research into the use of micro-Doppler signatures for target classi cation to address many defence and security challenges has been of increasing interest. In this paper, we present a review of the work published in the last 10 years on emerging applications of radar target analysis using micro-Doppler signatures. Speci cally we review micro-Doppler target signatures in bistatic SAR and ISAR, through-the-wall radar and ultrasound radar. This article has been compiled to provide radar practitioners with a unique reference source covering the latest developments in micro-Doppler analysis, extraction and mitigation techniques. The paper shows that this research area is highly active and fast moving and demonstrates that micro-Doppler techniques can provide important solutions to many radar target classification challenges

    Dr. Duane M. Jackson, Morehouse College, July 2011

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    This video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer

    Atypical Stüve-Wiedemann syndrome (STWS) masquerating as Cold-induced sweating syndrome (CISS): a patient homozygous for a LIFR mutation followed for 30 years

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    Introduction: Cold-induced sweating syndrome (CISS) is a rare autosomal recessive disorder caused by mutations in the CRLF1 or CLCF1 genes. It involves paradoxical sweating at cold ambient temperatures on the upper part of the body, along with craniofacial and skeletal features as progressive scoliosis. Mutations in LIFR (leukemia inhibitory factor receptor) responsible for the Stüve-Wiedemann syndrome (STWS), lead to a phenotype resembling CISS, with cold-induced sweating, scoliosis and cubitus valgus, but with a more severe clinical course. In fact, STWS is characterized by bowing of the long bones, respiratory distress, feeding difficulties, and hypertermic episodes responsible for early lethality. Materials and methods: We report clinical, molecular, skin biopsy, electrophysiological and temperature monitoring data of a 30-year-old Italian woman who has suffered from a cold-induced sweating and progressive scoliosis by the age of about 4 years. Results: Clinical data and the course showed a predominant CISS phenotype. Thermoregulatory sweat tests confirmed this paradoxical sweating response. There was clinical and electrophysiological evidence of a mild sensorimotor peripheral neuropathy. The morpho-functional study of cutaneous innervation showed a defective development of cutaneous sympathetic innervation with a lack of immunohistochemical shift from a noradrenergic to cholinergic phenotype. DNA sequencing showed homozygosity for a novel missense sequence variant, c2170> G in LIFR on 5p13-p12. Genome wide SNP arrays including parental samples revealed a complete maternal isodisomy for chromosome 5. Conclusions: Here, we report longitudinal observations on clinical consequences of LIFR dysfunction in a patient with a CISS-like phenotype

    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.

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    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states. By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement. To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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