3,779 research outputs found
Milano consolato nell' elettione a questo arciuescouado, e promotione alla sagra porpora dell' eminentissimo Federico Visconti : colla sua solennissima entrata seguita a' 11. genaro 1682 e fontioni antecedenti /
No full textFrontispiece coat of arms of Milan, engraved by Federico Agnelli.Signatures: pi⁴ A-G⁴ H⁴(-H4).Mode of access: Internet.Binding: limp vellum. Author & title written on spine
»It contained harbours that pleased me like sonnets«. Kleine Poetik der diegetischen Karte
No full textIn this article, Federico Italiano explores the relationship between literature and cartography. Beginning with Stevenson’s Treasure Island, the author frames the topic through a general theoretical lens on the spatial dimension of literary texts. He then focuses on a specific phenomenon of literary "carticity"—the diegetic presence of the map, that is, the map as an integral element of the narrative structure. Among others, Italiano examines the works of Houellebecq and Cormac McCarthy
Hybrid Electro-Neural Simulation Platform - Pudendal and sacral nerve models
No full textThis platform allows to simulate the electrical stimulation of peripheral nerves. It includes the scripts and data to replicate the results of Ciotti et al. 2023.Additional funding:
Gebert Rüf Stiftung foundation under the InnoBooster program (no. GRS-096/21 "MYLEG")
Innosuisse ICT program (no. 47462.1 IP-ICT "STEPUP"
The binding landscape of a partially-selective isopeptidase inhibitor with potent pro-death activity, based on the bis(arylidene)cyclohexanone scaffold
Full text linkDiaryldienone derivatives with accessible β-carbons show strong anti-neoplastic properties, related to their ability to make covalent adducts with free thiols by Michael addition, and low toxicity in vivo. Accumulation of poly- ubiquitylated proteins, activation of the unfolded protein response (UPR) and induction of cell death are universal hallmarks of their activities. These compounds have been characterized as inhibitors of isopeptidases, a family of cysteine-proteases, which de-conjugate ubiquitin and ubiquitin-like proteins from their targets. However, it is unclear whether they can also react with additional proteins. In this work, we utilized the biotin-conjugated diaryldienone- derivative named 2c, as a bait to purify novel cellular targets of these small molecules. Proteomic analyses have unveiled that, in addition to isopeptidases, these inhibitors can form stable covalent adducts with different intracellular proteins, thus potentially impacting on multiple functions of the cells, from cytoskeletal organization to metabolism. These widespread activities can explain the ability of diaryldienone derivatives to efficiently trigger different cell death pathways
Portrait of the Author in (Him/Her)self
No full textA fragment of a philosophical essay by Jean-Luc Nancy and Federico Ferrari titled Iconographie dell’auteur (Paris, 2005), published for the first time in Polish, that addresses the problem of a relationship between the image of the author and his/her work
Aneddoti e ricette a corte di Federico II nel XXI secolo : il buon cibo e il buon bere nel più antico Ateneo pubblico al mondo
Full text link[Italiano]: Questo volume rappresenta la finalizzazione di una iniziativa nata, condivisa ed interamente realizzata all'interno del gruppo social dei "Prof in cucina e in Cantina", che ha inteso raccogliere ricette e descrizioni aneddotiche di singoli Autori, appartenenti ai ruoli del personale docente e tecnico-amministrativo-bibliotecario dell'Ateneo federiciano, il più antico Ateneo pubblico al mondo. Aneddoti e ricette forniscono spaccati di vita quotidiana e ricostruzioni di eventi che hanno accompagnato gli Autori nei diversi percorsi formativi, sociali e lavorativi, e che non escludono riferimenti al recente periodo emergenziale della pandemia COVID-19. Ad introdurre il Volume è un menù federiciano, con una proposta di 3 pietanze che attualizzano ricette ed abitubini alimentari dell'epoca, e che hanno come riferimento il Liber de coquina, edito a corte di Federico II. Gli 8 Capitoli del volume raggruppano ricette e aneddoti per categorie, e ciascuno di essi è poi preceduto da un breve inserto con ulteriori riferimenti storici all'alimentazione a Corte di Federico II. Così, atmosfere vecchie e nuove, accompagnate dal sentore di aromi e da suggestioni ispirate al vissuto di ciascun Autore, si fondono per offrire a Lettrici e Lettori frammenti di quotidianità vissuti oggi a corte di Federico II, nel XXI secolo./[English]: The Volume represents the endpoint of a recent initiative, which was conceived, shared and fully realized within the social group of the "Prof in Cucina e in Cantina". Here, the several Authors, represented by the teaching and the technical/administrative/librarian staff of the Federico II University in Naples, the oldest public University in the world, propose recipes and anecdotal descriptions of their educational, social and work-related paths, including some episodes from the recent COVID-19 pandemic. A menu inspired to Frederick II introduces the book, with 3 recipes inspired to the Liber de coquina, a cooking manual compiled at the Emperor's court. Each of the following 8 thematic chapters of the book is also anticipated by a brief insert reporting historical reconstructions of the alimentary habits at the court of Frederick II. Thus, old and new atmospheres, accompanied by the scent of aromas and suggestions inspired by the experience of each Author, come together to offer Readers fragments of everyday life at the court of Frederick II, in the 21st century
Federico De Roberto, «L’imperio»
No full textIl breve saggio analizza l'incipit dell'Imperio di Federico De Roberto mettendo a fuoco come l'Autore riesca a dare una rappresentazione teatrale del parlamento e, con ciò, a desacralizzarne la funzione politica e a ridicolizzarne i principali attori: i parlamentari. Questo incipit è ovviamente funzionale alla successiva narrazione della progressiva delusione politica di Ranaldi.The short essay examines the incipit of "L'imperio" by Federico De Roberto focusing on how the author manages to give a theatrical performance of the parliament and, thereby, to desecration and ridiculing the political function of the main actors: the parliamentarians. This incipit is obviously functional to the narration of the progressive political disappointment of Ranaldi
Federico De Roberto, «L’imperio»
No full textIl breve saggio analizza l'incipit dell'Imperio di Federico De Roberto mettendo a fuoco come l'Autore riesca a dare una rappresentazione teatrale del parlamento e, con ciò, a desacralizzarne la funzione politica e a ridicolizzarne i principali attori: i parlamentari. Questo incipit è ovviamente funzionale alla successiva narrazione della progressiva delusione politica di Ranaldi.The short essay examines the incipit of "L'imperio" by Federico De Roberto focusing on how the author manages to give a theatrical performance of the parliament and, thereby, to desecration and ridiculing the political function of the main actors: the parliamentarians. This incipit is obviously functional to the narration of the progressive political disappointment of Ranaldi
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