1,720,982 research outputs found
The uraemic hypertensive patient. a therapeutic challenge-right you are (if you think so)
Full text linkHigh blood pressure (BP) is a leading cause of chronic kidney disease (CKD) and at the same time represents its most frequent complication. High BP is an independent risk factor for advanced CKD; on the other hand, at least 40% of patients with normal glomerular filtration rate (GFR) and virtually all patients with GFR <30 mL/min are hypertensive. CKD and microalbuminuria are powerful risk factors for cardiovascular morbidity and mortality. Consequently, in uraemic hypertension, it is of utmost importance to carefully manage both high BP and microalbuminuria, in order to slow down the progression of kidney damage and to reduce the incidence of cardiovascular events. The first purpose of the medical treatment in hypertensive patients is to normalize BP, regardless of the drug used. Nevertheless, some drugs have an 'additional' nephroprotective effect at the same BP target achieved. In this regard, first-line drugs are definitely renin-angiotensin-aldosterone inhibitors, mainly for their proved efficacy in reducing hypertension-related kidney damage and proteinuria. Anyway, a combined approach (two or more drugs) is usually needed to achieve the optimal BP target and reduce the worsening of CKD
Un sistema per la caratterizzazione automatica di elastici per fucili da pesca subacquea
No full textL’articolo descrive un banco di prova automatico progettato e realizzato con lo scopo di caratterizzare, in modo semplice, efficace e ripetibile il comportamento degli elastici utilizzati nei fucili per la pesca subacquea. Questi elastici, una volta allungati, grazie alla loro capacità di rilasciare rapidamente l’energia accumulata, sono oggi adottati come propulsori del dardo di questi specifici attrezzi da pesca. Il sistema realizzato consente la valutazione del loro comportamento ricavandone la curva sforzo-deformazione (σ-ε) al variare di alcuni parametri significativi quali l’elongazione massima percentuale e il tempo trascorso fra il termine della fase di allungamento e il momento del rilascio; i cicli di prova sono gestiti da un sofisticato circuito a microcontrollore appositamente progettato, gestito in remoto da uno strumento virtuale sviluppato in LabVIEW
Physiopathologic mechanism, clinical picture and therapeutic approach of acute myocardial failure
No full textAn automated test system for spearfishing rubbers characterization
No full textThis paper describes the realization of an automated system for rubber characterization in spearfishing applications. These materials, once lengthened, thanks to their ability to shrink very quickly, are used as dart propellers in fishing spears. The system permits the evaluation of the rubber behavior getting its stress vs. strain curve, allowing also the study of the effects of one or more parameters change like the maximum percentage elongation and the time elapsed between the stretching and shrinking phases at which the device under test is subjct
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Infectious endocarditis in dentistry practice: recent controversies and modes of the use of antibiotic prophylaxis
No full textA survey by questionnaire to assess the daily practice of the antibiotic prophylaxis of infective endocarditis by physicians attending post-graduate schools of the Institutes of Oral Surgery and Stomatology (Group A n = 83) and Cardiology (Group B n = 46) of the Second University of Naples has been conducted. They were asked about dental procedure and cardiopathies that require prophylaxis for infective endocarditis, the relationship between infective endocarditis and rheumatic disease and the provision of antibiotic. Extraction of tooth and dental and oral surgery have been reported as the most risky procedures. Moreover provision of antibiotic prophylaxis was suggested to patients not at risk (pacemaker or coronary artery bypass), and was not suggested in high risk conditions (mitral valve prolapse with regurgitation and hypertrophic cardiomyopathy). Most of the 50-60% practitioners usually start the prophylaxis 24-48 hours before the procedure and prolong it for 48-72 hours. These results underline the need for improvement of the knowledge for the antibiotic prophylaxis of infective endocarditis
Effects of telmisartan added to Angiotensin-converting enzyme inhibitors on mortality and morbidity in hemodialysis patients with chronic heart failure a double-blind, placebo-controlled trial.
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