18 research outputs found
Bank of Information and Algorithms as Instrument Aiding Managerial Personnel in Industrial Combines
No full textThe economic practice of the GDR shows that computer-based
information most often find their application in particular branches
of tho company's activity. These branch systems cannot satisfy
comprehensive demond for information of managerial personnel
in industrial plants und combinos.
Information services for the managerial personnel can be
successfully provided by the bank of information and algorithms
since such is the original task of this bank. It should store
the information which due to its importance for the managerial
staff must be very rapidly prepared as well as the Information
which plays a special role in management processes.
Specific nature of decision processes at higher levels of management
creates a difficulty in exact determination of information
requirements as declared by the managerial personnel of
those lovels as a basis fox- creation of information resources for
the information bank. The author suggests a practical solution
of this problem through analysis of information streams and
information resources existing already In companies and taking
also into consideration experience of other economic units in
this area. Next, the author presents 17 information complexes,
which should constitute the contens of the information bank.
The algorithms bank is to be an instrument making it possible
for the managerial personnel to process the information contained
in the information bank. In the algorithms bank there are
to be collected algorithms in the form of programme units, which
can be put together to receive the user's programme. The author
lists six group of algorithms which should be included into
the bank.
The dialogue between the user and the machine is the most
recommended way of using the bank of information and algorithms.
However duo to the fact that it calls for proper preparation of
the user, we cannot treat direct co-operation between the manager
and the digital machine as a standard solution, and it
must be carried out through a specialized staff unit acting the
role of a middleman.Zadanie pt. Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki nr 885/P-DUN/2014 zostało dofinansowane ze środków MNiSW w ramach działalności upowszechniającej naukę
Streptococcus pyogenes bacteremia in the setting of cholangitis [3]
No full text[No abstract available]ALTUCCI P, 1972, Bollettino dell'Istituto Sieroterapico Milanese, V51, P183; DAN M, 1990, REV INFECT DIS, V12, P537; DUMA RJ, 1969, MEDICINE, V48, P87; GOEPEL JR, 1980, BRIT MED J, V281, P1412; ISPAHANI P, 1988, J INFECTION, V16, P37, DOI 10.1016-S0163-4453(88)96073-2; LEVISON ME, 2000, MANDELL DOUGLAS BENN, P821; MURRAY HW, 1978, AM J MED, V64, P759, DOI 10.1016-0002-9343(78)90514-4; SIEVERT W, 1988, GASTROENTEROL CLIN N, V17, P245; TAPSALL JW, 1980, PATHOLOGY, V12, P403; TURNER F P, 1965, J Maine Med Assoc, V56, P1770
Overcoming the Valley of Death in a Service Organisation: Designing Innovation Implementation
No full textLarge and mature organisations, with their access to knowledge, capital and customers, are perfectly positioned to walk the road from invention to innovation; to turn promising breakthrough technologies and creative concepts into profitable and scalable business opportunities. However, these organisations rarely generate winds of creative destruction and instead start-ups disrupt them at an increasing pace (Anthony et al., 2018; Elsbach & Stigliani, 2018). Large and mature organisations struggle to innovate sustainably, in part because of their rigid organisational structures and processes that maintain the status quo (O’Reilly & Binns, 2019). To overcome this, organisations increasingly deploy ‘innovation hubs’. Innovation hubs are partially independent physical and managerial spaces intended as safe havens for exploratory activities. Examples of hubs are Xerox's’ PARC and Google X ‘the Moonshot Factory’. These are spaces where innovators find freedom to challenge the status quo and where there is space to consider alternatives, to experiment and to learn. Innovation hubs fuel the discussion of “what might be”.However, if organisations want to transform their business, they need to go beyond generating thought-provoking concepts. They need to implement promising concepts and integrate them with the rest of the organisation. Scholars call this gap that exists between concept generation and implementation the ‘Valley of Death’ (from heron: VoD) (Markham et al., 2010). It is crucial that organisations resolve issues related to the VoD if they want to reap the benefits of innovation. However, innovation implementation is a relatively under-examined field (Baer, 2012).Innovation implementations scholars predominantly focus on the proposed concepts. Questions arise, such as are the ideas ‘good’ enough? Are they ‘radical’? Do they serve an actual need? Alternatively, the innovator becomes the focal point of the study. There are stories (in both popular and academic writing) in which one well connected, head strong champion heroically shepherds an innovative concept into realisation, in resistance to incumbent forces. But it is risky for organisations to bet their future survival on the presence, capabilities and ultimately, success of lone champions who succeed despite organisational circumstances, not because of them (Dougherty & Hardy, 1996). Especially since failing to implement innovations often stems from factors beyond the control of champions8(Goepel et al., 2012). Thus, in this research, I take an approach to explore what organisational conditions help innovators to mitigate the VoD and achieve implementation.As a designer, I particularly focus on the relationship between design practices in innovation and the VoD. The Design Council states that design practices can mitigate the VoD (Kolarz et al., 2015). Others suggest they may actually aggravate the issue (Carlgren et al., 2016a). Recently, scholars have noted that designers need to consider implementation issues if they want to contribute to resolving organisational and society-level challenges (Dorst, 2019b; Norman & Stappers, 2015). In this thesis, I consider different conceptualisations of design in an innovation context (as problem solving and as inquiry) and shed light on the role of design in mitigating the VoD.Research DesignI performed this study using an action research approach (Reason & Bradbury, 2008a) in collaboration with a large heritage airline ‘FlyCo’ (kept anonymous for privacy reasons). FlyCo finds itself in a competitive landscape. Weighted down by large labour forces, considerable and long-term capital investments, and legacy management structures, FlyCo faces a battle to remain airborne while competing with both low-cost entrants (e.g., EasyJet) and high-quality ‘Gulf’ behemoths (e.g., Emirates). It operates in (for safety and security), a highly regulated and increasingly commoditised industry, which makes achieving innovation difficult yet rewarding. In response, FlyCo started an ambitious ‘architectural transformation’ (Safrudin et al., 2014) in which ‘design thinking’ was a central pillar to deliver a more customer-centred and cost-efficient service. This transformation required that FlyCo adjust its organisation to implement innovation projects more effectively. This situation provided a solid launching pad for this study. The research objectives, combined with the needs of FlyCo, informed the following main research question:How can design catalyse innovation implementation at a service organisation?Over a 14-month period, I embedded as an action researcher at ‘FlyCo’. I engaged employees from different levels of FlyCo to conduct actions as part of reflective, collaborative research cycles. The research contained three action research cycles (ARCs). Each ARC was performed in collaboration9with a distinct set of stakeholders and with different research aims. In the first ARC, my efforts focussed on building a network and an understanding of FlyCo and the VoD phenomenon. In ARC 2, the focus moved towards investigating conditions that contribute to a VoD with a focus on the role of design practices. In ARC 3, the focus again shifted towards how design interventions in organisational context could contribute to implementation success. Over the research period, I became increasingly immersed in FlyCo as my role shifted from being an outsider to obtaining increasingly influential positions (I became an interim manager in ARC 3 for example), which provided an opportunity to gather a rich dataset.During the embedded period, I employed multiple data gathering methods. Predominantly, I took part in- and observed corporate activities, resulting in 231 temporal observations (events). I captured observations and reflections in field notes, resulting in 426 pages of notes and drawings. Additionally, I gathered internal documents (such as strategies, project proposals, training manuals). Finally, 48 interviews were conducted at multiple intervals during the study. Of these interviews, 17 were semi-structured, audio-recorded, and transcribed, whilst 31 were conversational and recorded via hand-written notes. I initially analysed the data using a visual mapping strategy. Subsequently, a thematic analysis was performed using NVivo software. A breakdown between identified themes and existing literature finally informed a narrative analysis strategy. Together, this data collection and analysis strategy helped to observe nuances in FlyCo's innovation and implementation processes that can evade detection by other ‘outside-in’ research designs.InsightsThe data inform four sets of insights. Extant research on innovation implementation has focussed on product/manufacturing organisations (with historically large R&D departments) that aim to reach additional customers through new/improved products. In this context, managers and scholars noticed that R&D output did not reach controlled stage-gate New Product Development (NPD) processes. But innovation hubs are also increasingly popular at service organisations (Blindenbach-Driessen & Van Den Ende, 2014), which have different (and less structured) innovation processes. The first set of insights describes an exploration and re-conceptualisation of the VoD phenomenon in a service organisation context. I identify three10organisational unit types that contribute to innovation: exploration hubs, support partners and operational units. In this context, the metaphor of a singular ‘valley’ between two contributing units appears erroneous, as implementation challenges exceed the dichotomous relationship between design and production.A deeper investigation into the mechanism that drives the VoD shaped the second set of insights, which highlights the role of institutions, specifically organisational logics. At FlyCo, a constellation of three organisational logics and the absence of a recombination strategy fosters an environment inhibiting resource pooling between organisational units. The three logics inform conflicts on three issues: innovation priorities, innovation processes and problem frames. As logics guide legitimacy judgement, conflicts between logics lead to a Not-Invented-Here attitude from gatekeepers towards concepts from ‘foreign’ logics. Consequently, champions can’t gather the resources needed for implementation and their concepts end in a VoD.The third set of insights describes how 10 barriers contribute to the VoD. I identify four barriers related to organisation properties of FlyCo. A complex and siloed organisation, the absence of a shared service vision, decentralised innovation portfolio management, and a competing internal innovation marketplace stimulate a VoD. Two barriers describe project characteristics related to the VoD: founding problem frames in an inferior domain and proposed solutions with a weak fit with the existing service system. Two process-related barriers highlight how engaging stakeholders late in the innovation process and inadequate communication of project decisions contributes to a VoD. Finally, two barriers describe how the organisational set-up of an exploration hub contributes to a VoD: when there is no ‘Shadow of the Future’ and when hubs have limited access to resources, they struggle to mitigate the VoD.The fourth set of insights explores the relation of design practices with innovation implementation. When viewed as a problem-solving approach, I exhibit how design practices contribute to mitigating implementation issues by fostering more holistic concepts and an innovation process with engaged and aligned stakeholders. However, as an inquiry process, design practices contribute to a VoD when projects are reframed such that the aspired value shifts. A VoD then appears in two situations: if the new working principle requires new stakeholders (not part of the founding problem frame) to become involved, or if not, all involved stakeholders accept the new frame. In11addition, I deployed design practices to create new organisational infrastructure which fosters innovation implementation success. These practices inform a sense of shared ownership and novel organisation designs, but they also introduce challenges that require further investigation.Contributions and GuidelinesOne principal contribution to literature is the reconceptualisation of service innovation implementation. Instead of three sequential phases, ‘elaboration’, ‘championing’ and ‘production’ (Perry-Smith & Mannucci, 2017) are three reiterating micro-processes. These micro-processes constitute two innovation-to-implementation process streams. In one process stream, innovation teams solve ‘innovation challenges’ (Dougherty & Hardy, 1996) through concept elaboration and production. In the other stream, championing in the organisation sphere aims to solve ‘innovation-to-organisation challenges’ (Dougherty & Hardy, 1996). In line with this conceptualisation, I propose to define the VoD in this context as ‘when concept development terminates because champions fail to gather the required resources for further development because of innovation-to-organisation challenges’.Second, I propose a classification of three types of organisational units involved in innovation. In service organisations, achieving innovation requires mitigating gaps between (1) explorative units, (2) support resources, and (3) operational units. I challenge whether the dichotomous conceptualisation of a VoD does justice to the complexities of achieving alignment for reform within service organisations.The findings add to a growing body of knowledge that considers the role of institutions in realising (service) innovation. I add that, besides on an ecosystem level, organisational level ‘Logics matter when coordinating resources’ (Edvardsson et al., 2014) in service innovation. I identify three issues where misalignment between organisational logics hampers innovation implementation: innovation priorities, innovation processes and problem frames. I propose that besides contextual, spatial, and organisational boundaries (Antons & Piller, 2015), organisational logic boundaries can trigger a Not Invented Here attitude.Insights from this study suggest a complicated relationship between design innovation and the successful implementation of these innovations, which I call the ‘Design Implementation Paradox’. Design principles and practices related to experimentation, experiential learning, and embracing12diversity contribute to implementation success. Practices related to embracing diversity, user-centricity and materialisation contribute to resolving innovation-to-organisation challenges and mitigating logic conflicts, and thus to implementation success. However, design can also contribute to a VoD when reframing leads to a shift in the stakeholder field or when champions cannot convince involved stakeholders of a new frame. This study represents an initial exploration into this relation, but more research is needed.The final contribution to theory is 10 organisational barriers identified that contribute to the VoD in a service organisation. For example, by exhibiting how an internal innovation ‘marketplace’ encourages competing behaviour as opposed to collaborative behaviour, which hinders innovation implementation.The insights inform six guidelines for managers, specifically for those who shape organisational conditions, to design organisational infrastructure that promotes innovation implementation. These guidelines describe organisational infrastructure that contributes to mitigating the VoD:1. To resolve innovation-to-organisation problems, service organisations can use innovation hubs because this infrastructure facilitates the required social dynamics.2. To avoid a Not Invented Here attitude, the infrastructure of these innovation hubs can promote institutionalisation and legitimisation of innovation concepts.3. To motivate aligned innovation processes and ‘implementable’ concepts, the infrastructure of these hubs must act as a ‘shadow of the future’.14. To align decisions making across organisational units, a service vision - which describes what value the organisation wants to create in the future - should be formulated and shared.5. To ensure alignment between resource allocation and the innovation vision, and to spot potential VoD issues, centralised innovation portfolio management can be applied.6. To align the innovation portfolio with the current technological and organisational system, the service system-fit framework can be applied.1 An example of such infrastructure is when incentives of innovation hubs relate to implemented innovations, not merely proposed concepts.13This research emphasises the need to study implementation in design research, if designers aim to realise societal impact. Design education needs to adjust to fit the more strategic role that design is assuming. If design is indeed going ‘beyond design’ (Dorst, 2019b) to contribute to solving the world challenges, then we need to go beyond teaching future designers how to generate innovative interfaces, products, and systems. We need to teach them how to contribute to implementation and, ultimately, impact. This implies assuming a broader understanding of design, offering students tools and skills to become more sensitive to organisational context and helping them understand what influences implementation and what strategies they may pursue to achieve implementation. This requires a realisation that the road to implementation is paved with team players and that besides being great pitchers, designers need to learn how to knock the ball out of the park.Above all, this research emphasises the limits of the ‘rogue innovator’ narrative and provides principles for organisational leaders of service organisations that face transformation to mitigate their dependence on innovation champions and instead design organisational infrastructure that facilitates innovation implementation.Marketing and Consumer Researc
Delirium in hospitalized COVID-19 patients: Predictors and implications for patient outcome
No full textIntroduction Delirium is recognized as a severe complication of coronavirus-disease-2019 (COVID-19). COVID-19-associated delirium has been linked to worse patient outcomes and is considered to be of multifactorial origin. Here we sought to evaluate the incidence and risk factors of delirium in hospitalized COVID-19 patients, along with its impact on clinical outcome. Methods Consecutive adult COVID-19 patients admitted to a tertiary academic referral hospital between March 1st and December 31st, 2020 were included. Potential risk factors for delirium were evaluated, including: age, gender, disease severity (as per the highest WHO grading reached during admission), laboratory parameters for infection and renal function (as per their most extreme values), and presence of comorbidities. To assess the relative strength of risk factors for predicting the occurrence of delirium, we performed a random-forest survival analysis. Results 347 patients with positive COVID-19 PCR test and median age 68.2 [IQR 55.5, 80.5] years were included. Of those, 79 patients (22.8%) developed delirium, 81 (23.3%) were transferred to ICU, 58 (16.7%) died. 163 (73.8%) patients were discharged home, 13 (5.9%) to another hospital, 32 (14.5%) to nursing homes, 13 (5.9%) to rehabilitation with an overall median admission-to-discharge time of 53 [IQR 14, 195] days. The strongest predictors for the occurrence of delirium were blood urea nitrogen (minimal depth value (MD): 3.33), age (MD: 3.75), disease severity (as captured by WHO grading; MD: 3.93), leukocyte count (MD: 4.22), the presence of a neurodegenerative history (MD: 4.43), ferritin (MD: 4.46) and creatinine (MD: 4.59) levels. Conclusion The risk of delirium in COVID-19 can be stratified based on COVID-19 disease severity and–similar to delirium associated with other respiratory infections–the factors advanced age, neurodegenerative disease history, and presence of elevated infection and renal-retention parameters. Screening for these risk factors may facilitate early identification of patients at high-risk for COVID-19-associated delirium. © 2022 Wilke et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Envolvimento da via do óxido nítrico no tratamento e na patogenia da hiperplasia prostática benigna
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.As evidências da participação do óxido nítrico (NO) na função prostática nos levaram a estudar o envolvimento deste na Hiperplasia Prostática Benigna (HPB). Na sintomatologia obstrutiva da HPB são identificados um componente mecânico, que consiste no crescimento do tecido glandular, e um dinâmico, relacionado ao aumento do tônus da musculatura lisa da próstata e uretra, estimulada pelos receptores a1-adrenérgicos e onde o NO pode exercer um papel regulatório. Atualmente a finasterida e o PermixonÒ são os medicamentos mais utilizados para o tratamento da HPB. Este trabalho buscou relacionar o envolvimento do NO na patogenia e nos efeitos dos tratamentos para a HPB, utilizando um modelo de hipertrofia prostática (HP) em ratos. Após 30 dias de tratamento, ocorreu uma redução nos níveis de NO nos animais com HP. O PermixonÒ aumentou o NO para níveis próximos aos dos animais normais, o que pode representar um mecanismo de ação na melhora dos sintomas. A finasterida não alterou os níveis de NO. A diminuição dos níveis de NO na próstata com HPB pode influenciar os sintomas obstrutivos resultantes de uma exacerbação dos efeitos a-adrenérgicos sobre a contração da musculatura lisa prostática. Algumas evidências indicam uma relação entre HPB e câncer prostático através de alterações nas defesas antioxidantes do tecido prostático que levariam às lesões no DNA. Assim, foi avaliado o estresse oxidativo nos ratos com HP. Ficou caracterizada uma condição de estresse oxidativo vinculada à HP, através dos níveis diminuídos de três enzimas antioxidantes e aumento do dano celular no fígado de ratos
Mixed urinary incontinence: international urogynecological association research and development committee opinion
No full textBackground and aim The definition as well as the treatment of women with mixed urinary incontinence (MUI) is controversial. Since women with MUI are a heterogeneous group, the treatment of MUI requires an individual assessment of the symptom components: stress urinary incontinence, urinary urgency, urgency urinary incontinence, urinary frequency, and nocturia. The purpose of this paper is to summarize the current literature and give an evidence-based review of the assessment and treatment of MUI. Methods A working subcommittee from the International Urogynecological Association (IUGA) Research and Development (RandD) Committee was formed. An initial document addressing the diagnosis and management of MUI was drafted based on a literature review. After evaluation by the entire IUGA RandD Committee, revisions were made, and the final document represents the IUGA RandD Committee Opinion on MUI. Results This RandD Committee Opinion reviews the literature on MUI and summarizes the assessment and treatment with evidence-based recommendations. Conclusions The diagnosis of MUI encompasses a very heterogeneous group of women. The evaluation and treatment requires an individualized approach. The use of validated questionnaires is recommended to assess urinary incontinence symptoms and effect on quality of life. Conservative therapy is suggested as a first-line approach; if surgery is contemplated, urodynamic investigation is recommended. 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j the editor of Woman's Home Com-
j panton for January. "Mr. Roosevelt has made nrtstake*. as be would
' be the last to deny, bnt be bas done
, the country one service which is not
j written on the statute books or on
I tbe records of his official achleve-
, meats. He has promoted tn the paper* which tbe people read, and,
Peter P. Bilhorn, of Chicago, a
gifted gospel singer, will begin ft
two-weeks' evangelistic meeting
with the First Baptist Church of San
Pranctsco Sunday. Januaj-j l*th. He*
', more ImpojjajtLia-uTe winds of lliaf-a-ffl-n*"ssgstea- oy hht wife In slng-
Tpeople themselves, an active discussion of questions ibst had become
'. nbelfworn from neglect. He has
given publicity to tbe Ten Cona-
mandmenta: be baa refurbished the
{ Beatitude*: be has popularited
' common honesty. For these things
let us give him credit."
Singing Evangelist
Comes to Coast
PETER P. BILHORN WILL tlol.lt
NKKIHri OP Ml I I I \c.- IN SAN
FRANCISCO.
log and In women's meetings.
Dr. H. J. Vosburg. of Oakland,
will be -the preacher the first week,
January IS-3. and Rev. ft W. Drtn-
stad. stat* superintendent of missions, tbe second week, January
IS-M.
Among the features of especial
interest connected with the visit of
lUllroed Karwtag* t.row. ! the United State* naval fleet lo San
New York. Dec. J I. - Publication Praarisco last summer was the pre-
waa made yeaterday of the earning* aenUtlon of a folding organ to e»ch
for November of the Southern Pa-j°f the vessels by tbe maker. P. P.
rtftc and fnlon Pacific sys- Bllborn of Chicago. His splendid
terns Those of the Southern S-t **» designed to relieve the mo-
Pacific showed a gross d*cr*ft*e of! ■otooy or the long voyages and pro-
94S2.SS6. converted Into a net •*-{'-*• instruments for the nee or the
crease of T««.4<: through a r*-j»« l» ""lal and religious gatber-
: duct ion in operating expense* or II - '"St.
( 211,313 and a reduction of Uses of This blg-besrted German, whoa*
I8,:.'-:■. Tnlon Pacific showed a whole life la devoted to tbe welfare
decrease In gross of 9164.841; a de-' of his fellow men. was deeply Ira
.crease tn operating expense* of pressed with tbe opportunities exist-
' t*9>,S4d; taxes increased 110,471. log lo San Franrteco for work, es-
' and net revenue Increased 1534,Ote.
FRAU LIVONIUS. A FAVORITE IN WASHINGTON SOCIETY.
rran Livonia*, wife of tbe mlliury attache of the German embassy at are soon
Waablnglon. Is one of tbe moat beautiful women In ■eclety at the capita!. Country
Asia* from bar personal charms *be ts a brilliant coo versa ttonallst and la the —
foe of nearly every soclsl eveat whtcb takes place in diplomatic cirri**.
la greatly admired by the president and Mrs Rnosevsit.
' When she hit him with a golf-
ball, did It knock htm senseless?"
"I sues* so. I understand they
merry."—Town and
Made In <*Worwia
of 8gs, pcauae* and
Made la a cleanly
Figprune Cereal
PIOS
•w*et
luscious
laxltlve
PRINKS
f urn lab
heal for
the body
A wholesome and
pleasas.
tale by your grocer
*)■ AIMS
netritlv*
strength
giving
drinh
Golden
Gate
Coffee
The kind thst makes tbe break-
fast real Coffee through and
through - always the saaw.
Year groosr will grind It—
b*tUr if ground at bom*—not
too fin*.
pertally among the young men. and
la lo return to the coast this winter
for evangelistic work In the larger
rtt.es Mr. Bllborn love* his lei-
lowmeu. and for twenty-five years
he has been devoting his splendid
talent as a singer to the proclaiming
of the gospel In sacred song. He Is
well known as the author of some
of the most popular goepel songs of
the day. and haa labored with prominent evangelists east snd west.
He ts perhaps beat' known by his
song. "Sweet Peace, the Gift of
Ood's Love." and probably no song
In his entire repertoire Is more often
called tor than this simple melody
Of Christian faith and experience.
i His unfailing sympathy with aaen
s and his constant love for the Master
make him a most attractive and effective evangelist, although he Is
not bimaeir a minister, and usually
hanTh-i assistance of psstore or other preachers in hla meetings.
4.50
Ragnlar Price
I'kily Palo Alto Time*. 1 year S4.S0
Woman's Home Companion
Our Club Rate
5.35
Ragular Price
Daily Palo Alto Time*, t year S4-S0
Review of Reviews. 1 year.. as.oo
McClure's Magazine. 1 year . . 1JJO
Woman's Home Companion,
l year rr,
• I0*J5
Our Club Rate
6.50
Phone, write or '■"/°t m-r-
TIMES OFFICE
Cor. Hamilton and Ramona Palo Alto 115
Similar low rial, rates with oar weekly. The Palo Alt**, on aswsuV
RewrfnUusts of Respect.
Palo AHo Council, No. 4?«. Fraternal Aid Association, at a meeting
held on December lath, adopted the
following resolutions or respect:
Whereas. The Divine Hand has
vtaRed our council and removed
from our midst our nrother, Willi
(' 1'lfaal. w* therefore. In council
! assembled, do express our sincere
sorrow for his loss, and sympathy
* for tbose bereaved of tnelr dear one.
| aad order thst the charter or our
council be draped In mourning and
a copy of these resolutions he spread
upon tbe minutes of our council and
published In the dally papers of
Palo Alto.
Jennie R. Roniller. Syron C. Hall,
Annie la Psire. committee.
Whereas. The Divine Hand has
visited our council end removed
from our midst our brother. Frederick IE. Peterson, we therefore, in
eonnctl assembled, do ex pre— out
sincere sorrow for bte loss, and sym
pfttfay for those bereaved of their
dear nne. and order that the charter of oar council b* draped li
smournlng and a copy of the reso)o<
tlon be spread upon tbe minutes of
our council snd. published In tbe
dslly papers of Palo Alto.
Jennie R. Rouilter, Myron E. Hall
Annie L* Pelre. committee
GMOLOGICAL SOCIETY HOLDH
SESSION AT STANFORD
At the ninth annual session of the
COrdllleran section or the American
neologies! Society.held Thursday at
Stanford. Doctor Brenner, vice-president of the university, and Professor Rogers of the physics department read paper* treating of the
general subject of earthquake*.
Professor Rogers told of an Interesting scientific experiment by,
means of which be bad proved that
wet ground was, more violently
shaken by t-.mho.uake. than dry
ground. ""Wet" and dry sand wss
placed In boxes snd both subjected
to the same shaking force, with the
result that the wet aand hung together like a bowl or jelly. Miniature buildings constructed upon the
surface of the wet sand were easily
sbsken down.
As s corroboration of the result
of Professor Rogers' experiments.
Doctor Brenner told of hla Investl-
gstions of earthQuakes la several
countries. At San Francisco. Valparaiso. Mendoxo and Kingston the
greatest damage was done In field
land., very wet aad soggy, which
hung together when the shock came
and did not dlatrlbute the violence.
Tbe heaviest damage tn San Francisco, said L-octor Branner, occurred
at the postoffice building, which was
constructed on wet filled land. At
Valparaiso the same result was
clearly evident, the structures placed
upon the soil washed up by the sea
going down like cards.
The Stanford scientific Instructors
are unwilling to discuss the Italian
earthquake, saying that they are not
familiar enough with tbe geology of
the country to express an opinion.
At the second day's session on
Friday there were about thirty scientists present and the papers read
were aa follows: "Notes on the Geology of Southern Japan," by Robert V. Anderson of Stanford University: "The Peat Deposits of the
Lower Sacramento and San Joaquin
Rivers," by W. 0. Wright of San
Franrleeo; "Mineral. From the
Coast Range* of California," by A.
F. Rogers of Stanford; "A Synopsis
or the Stratigraphy or California."
by Jame* Per/In bmltb of Stanford;
"Structure of the Ceneral Portion of
the Coast Ranges of California." by
J. F. Newsoni of Stanford; "Resume
of the Geology of Brasll," by Orvllle
A. Derby of Rio Janeiro; "The Geology of the Region of Diamonds and
Carbooftdos In Brasll," by J. C
Brenner.
Southern Pacific
Time Table.
(Chang, tn time, Effact Saadar.
Sant.moar II. lilt.)
Toward ftaa lHaausae*.
No. S3 6:H a. a.
No. 36 t Valencia) 6:61 a. at
No. J7 1:41 a. a.
No SI fLoa Oatoa cutoff, ax. San.) ... 7:01 a. m.
No. .1 (*x Sun.) 7:11 a. a.
No 41 (ai Sua.) 7:41 a. a.
No. 46 (ax Sua.) •:•• a. al.
No. 47 trM a. a.
no. iijuj^.**—-••• •iti.i.av.
No. SI ~ 11:14 a. a.
No. 41 ll:0j P. a.
No. 61 (ax. tan.) t: 17 j. a.
No.- SI 1:01 p. aa.
No. 6S 4:IT p. a.
No. 61 «:01 p. a.
No. 61 4:11 p. fa.
No. SI ..'. T:4I p. a.
No. IJ T:4t a. a.
No. 14 •:!• a. XI.
No. 14 1:61 a. a.
No. SS 11:41 a- at.
No. 40 11:41 p. Xa.
No. 41 1:11 P. X*.
No. IS (oa Sag. Santa
Crax . Par. 0.). 1:11 p. la.
No. 10 4:11 p. xa. .
No. 44 »:ll p. a.
No. 41 6:64 p. a.
No. 41 (ax Baa.) CM p. a.
So. >• (ax. Sun.) 1:14 p. a.
No. 61 6:45 p. a.
No. 64 (ax was.. Los
Oatoa eatot) ... 7:01 p. a.
S». H f!«4 p. ax.
Na. II (Loa aag. axp.). 4:61 p. a.
Ww- II ■Mlll4t a. a.
SAIL gCBaTDCUa.
(la aCaet Saptaakar .«. llll.)
From North—7:41-a. a- 11:41.
t:46 and 6:64 p. a.: Ssadar*. 7:41
a. a.
From South—7:41. 10:11 aad
11:14 a. a.. 1:11 and 1:11 p. a..
Suudays, 7:41 aad 10:60 a. m.
Proa Stanford Unlwaitp—1:11
11 a a.. I and I p. a.
1:16 and 10 a. a.
To North—7:11. 1:01 ud 11:44
a. n>.. S:IS aad 4:01 p. a.: aaiaaxa,
10:10 a. a.. 7:14 p. a.
To Strath—7:11 a. a.. 11:10. 1:11
aad 1:11 p. a.: Saudaja, 7:11 aad
10:10 a. a.
To Stanford I'nlfaratty—7:11 aad
11:04 a. a.. 1:41 p. r ' '
7:16 aad 11:41 a. a.
In Hoc
Soring that tn. board of In*-
holder*. riMUd • ta draft charter,
for in, Ath.n, of Alameda coaatr,
1. "up a .tump" for a design for a
I municipal seal. Serrelarr Wall,
: Ilrurj of th. B.rk.1^ cbamnar of
' Conun.rca, ha* wrlttaa to' Prof.
j William Carey Joo«a to. noggntloo
: that th. ,torh la th. moat anproprt-
! ate emblem far th. town. bMeune
'the birth rata la bvrk.le. I. higher
| than In aar other California city,
whit, the death rate among rbil-
I dren la lower than in any other city
j of th. ataut.
! Secretary hrury » auggeatioB la an
j excellent one. bat we beg to amend
1 It by euggeetlog that th. Berkeley
! atork ahoald ba represented aa alt'
I ting on an adding machine aad read-
j Ing Preeldeat Rooaev.lt'i famous
i gagaaggaj on race suicide. — San Fran
1 elsco Star.
Mr,. Athertow*, L*teet Sr.t^l.
{ All who hare read and enjoyed
I the preelou, works of Mrs. Gertrude
! Atbertoo will be delighted with her
! latent aad probably Btroagast work,
j entitled "The Oorgeems Isle." The
scene ts laid amid the high lights
and brilliant setting of one of tbe
Islands of th* West Indies, and pre-
aenl* a new sad compelling problem
of life. Thin story is appearing In
the October Smart Set.
The Leading Newspaper
ot
SAN FRANCISCX)
I*
I
The Call
Recently"* break ooeorred In (be
lev** at Coyote Island, a section of
slj.iv feet giving way snd the tide
flooding the reclaimed land near Ban
Mateo. Tbe wells of the Ban Mateo
waterworks are located In the flooded district and tbe tide soon III led
them with brarklah water. The
pumps were stopped and the town
Is now depending npon Spring Valley for water.
Harold—What did she say when
you torsed out the gas and kissed j
her?
Rupert Said she felt as If she'
never wanted to see my face sgalft.l
- Tit Hii..
The Junior CAUL
tor the 4 lilldren **»*■ FRMR seerj
week with the Batnroay *■*■*.
TBT IT
YOl' WILL SB PLaUBMD
tS Coats per Month,
Sample Copies Free
Write I*
San Franciaco Call.
The Dally Times 10* ■ week.
Ranches Close In!
For Sale and Exchange ;
FOI'R ACRE* Klegant bonse
and barn and family orchard, one
and one-half miles out on county
road, situated on Important corner.
Will accept small place la Palo Alto
aa part psyment.
EIGHTEEN ACRES— Nesrty all
in orchard and vineyard, a modern
cottage of B»e room*, two good
wells, abundance of water; grand
new, two miles from Los Altos. In
foothills. Exchange for Palo Alto
home.
TWENTT-THREE ACRES—Unimproved lend beautifully tln.berod.|
rolling, grand view, pest sine and
orchard soil; four miles In foot-]
hills. To be sold at low figure.,
Will accept residence lot lo Pftloj
Alto ss part payment.
THIRTT-EIOHT ACREfl —Three
miles out In foothills; ««t> fall-
bearing orchard tr/ee*. abundance
good timber; host soil for vineyard;
grand elevation and views, Sacrifice price of lees than 100 an acre
In cash. Owner would entertain
good residence lot In Pslo Alto as
part payment.
OVER 100 RANCHES—Large and
small. Improved and unimproved, on
our Hat. Some will exchange. All
are bargains. Send for Illustrated
ratalogue. Offices open every day In
the year.
Tntesasowe 51.
FREDERIC HEBARD « CO-
MaytteM. CsU.
ritnctainKiimnmB
SAN FRANCISCO
"CHRONICLE*
aa sissannxM uns
SI
Th Week* "On*k"
a*h) vary sees asnhssy sswryepsr
s*saaaaaat fc> the aa*n Waa*,
$1.50 a Year
sens sai s**l»t ssab ws* s» sn ass*-
■» aUSIIiISS, SSa** fta. ■tats* lilt*..
taSa* **• a" is *Um taws* *tt*
■ 1 arvrtJl:.* SS Ula OaSM.
Is s**dtBg 1* rear .ubscriptlsk*.
"teas*
HH.de YOIJHO,
•" ■yasslsil -Y^egmlrU,-
8aa rraactacs, Ca
0002
No full textDAILY PALO ALTO TIMES. SATURDAY. MARCH 6, I
2_.
»"»-•-*♦♦**♦***>♦♦*>*
First
♦ •
INational Bank!
LAID OFI»
Th. Iajo» aaa so terrors lor
th. msn with i bank aoeoaBt.
Is the wsrs of work, whea
moBev was comlo. In. has
sood sense tsniht blm to pro-
-Ms itiiut tb. i.roif b, ds-
posltlnr. a oortloB of bU earn-
lags Ib the baak.
New be rasas tbe bee-wit ol
kla fore.lt>,,
OPEN AM ACCOUNT WITH
CS TODAY.
Stanford University
News and Doings
Capital - - 5,400
OFt'i*. "COS:
C. K Child*, president
Jobs Dnd&sld. Vlce-Pre*Me**c
Bll Klag, Caaatar.
C E Jordan. Aaat. Cashier. •
DIRBCTORS t
C R Child*
John Dudlleld
C. i. Smith.
H. W, SImkin* I
Ell King I
Or. R. L Wilbur j
3. B. Leklr I
>*♦* •"♦-»**.**♦ • ..••••....•..„
l.si.iMH DAYLIGHT SAVIN O
RILL MOVING ALONG.
London. March t.—Tbe daylight
aavings bill haa paaecd It* second
reading In the house of commons
by 130 vote* te 91.
Thl* bill was drafted to promot*
the earlier use or daylight In certain months yearly by putting, forward tbe clock 30 minutes on tour
sacceeelve Sundays In April and by
reversing tbe process on tour Son-
days In September,
Tbe bill, It haa been argued,
would be of great benefit to all
classes by giving the people Just bo
mucb more sunlight In which to
bave recreation while the wage
earner would retire earlier and
thereby save tbe expense or light
MstnegiBC Itaard of Qawd.
Al the meeting of tbe sophomore
clsss yesterday President F. II
Hilton appointed the 1911 Quard
board of control. The men appointed are 0. A. Olts. chairman. J. D.
Rutledge. J. K. Thompson. W. R.
Plttenger and J. H. l^.-ds
Among the olber buslm-ss trans-
a-l**d. tbe class voted to gi\e s dinner to the "7-20-B** cesl and commute*. Chairman J. E. Thompson
was extended a hearty vote of
thanks for hla »mrtent work lo producing tbe play, and wss also voted
the sum of 930 to defray tb* expense of the flue* Imposed upon
himself and three other members of
the clsss for posting "7-30-S" dodger* In Palo Alto.
President Hilton Issued s call for
won to sign up nnd enter tbe Marathon race. In response, forty-»evfln
classmen signed for ta* race. W.
Wyrnan wss appointed captain.
President Hilton sppolnted a
committee to plan aod take charge
of the class Interests is tbs Junior-
day swimming rs.****. The members
are A. Taylor, chairman, T. C Dye
and C. B. Tallant.
Fieahnw-n at Oakland.
The member* of tbe freshman
track team, which will meet St. Mary* College at Oakland this afternoon., left the campus at 9:31 thla
morning under lhe charge ot Manager Stewart.
(trailing Traais l ..art*
Work has commenced on tbe construction of three new tennis courts
In the field directly In front of Bn-
cina Hall. These courts were ordered some time ago by the board
of control, and would have been In
use now had It not been for tb*
heavy rains. Tbey will only bave a
dirt surface at present, bat It is exported tbat they will be regraded
and oiled next summer, after tbe
spring rains have hardened and
packed thorn down.
Subscribe fee tas Dally 11a.aa.
win
Founder*' day. March 9th, ibe
anniversary of the birth of Lelsnd
Stanford, will be observed this yesr
as Is the yearly custom. Next Tues
day has been set apart for epeciel
university exercises. The bulletin
snnounclng the exercises says that tt
Is not a holiday
At 1I:1S there will be a university assembly, which sll students
are expected to attend. University
i-xcrctsa* will be suspended from
13:15 Tneeday until 11:15 on Wedneaday. when unlveralty work will
again tie resumed.
Dr. David Starr Jordan will speak
on Mr*. Jane L. Stanford. A aecond speaker will bo Professor A. C.
Miller of the University of California. Profeaaor. Miller Is th* preeent holder of the Flood professorship fn ecoaomlcs sad commerce.
GOOD BUSINESS.
BIRD AND ARBOR DAY nil.I,
IS SI-tZN'KD RY OOVKRNOR
The Time* Is la receipt of a message from Mra. L. B. Hurst, chairman of the California Club committee la charge of the bird and arbor
day and the joint custodian bills,
announcing that Governor Glllett
has signed th* bird and arbor dsy
bill. This measure provides for
exercises In the public schools on
March 7Ih Luther lUrhatik *
birthday, but does not make the
day a holiday.
The day will be observed generally this year and on Monday tbe Palo
Alto schools will have exerclee* appropriate to the ot-ca*loe. The arbor day manual just Issued from
tb* office of tbe state superintendent
of schools contains programs for
tb* exercises and much otber mailer of Intereat, One of the moot
commendable feature* of tbe day ts
the encoragement lended to the
planting of tree*.
The Thrifty Yeung Man Found * Pref-
ilsbl* lnv*atm**it.
A millionaire, hoping to encourage
hi* yoaag aoa la way* of thrift, prom-
lead to k!\ i' him 2 per cent a month intereat upon sny money Ibst be might
■sv* out of bl* allowance and deposit
In lb* paternal treasury. The young
man was getting £5 a week for pocket
money and promised to abow bis appreciation or bis father's affectionate
offer. He began to make deposits
wllbout delay and kept the practice op
srtth remarkable regularity.
Tbe old gentleman noticed presently
that tbe deposits exceeded lhe whole
of tbe boy'* allowance, but accounted
Cor ibis by supposing tbat be bad
eeved *om* money previously, Bsoldo
thl*. he ri-.iv.s] money frequently
from hla mother. Bo tbe fond parent
tejolcod tn th«* wring dlspoeltion tbst
bla *on was displaying.
Tbls cootlnucd until tbe boy's deposits assumed such dJ—ens Ions aa to
demand an rxplanation. It then turned
oat that moat of tbe money be bad
been depositing had been borrowed.
Inasmuch as he eras drawing Interest
on bis deposits st 3 per cent per naoath
and was paying only 10 per cent per
yesr for tbem be bsd found the business decidedly attractive and profitable.
—Pearson"* Weekly.
UNDER IS DANQEROUS.
Mormon lam Kxplalnrd.
Sixteen traveling elder* of th*
Church ot Jeans Christ of Latter
Day Saints will hold service* In Os-
trander Hall. 371 University avenue. Sunday at 1 p. m and 7:30
p. in. All welcome. No collection.
The goepel explained In Its full*
nes* ss taught hy Christ while on
earth. New truths rsveeled from
heaven. Th* origin ot the American Indian from their own history.
THE DEVILFISH.
H* Is Not a Msn Catar. but * 0*ntly
Rs«rtcJ Monitar.
Contrary to popular belief, the devil-
Bab Is not a man eater, according to
aa official publication Issued by tb*
Smlthwonlsn Institution. Wsshlngton.
after su aulhorltutlve stndy of tbs rob*
Ject by Dr. Tbt**.dore GUI. st-soctate ln
soology tn the tunlongl museum. "Tbe
food of the devilfishes," hr says, "so
far from being largo animals and occasionally a man or an, as has »*een alleged, appears io be chiefly tbe small
crabs, shrimps and other crastacssns
aad young or small tubes. Itsrety does
oa* prey on large fishes."
Dr. Dili says that In a number of respects tbe young devilfish grows ap
natter nursing and training remarkably
like thst of s human being. It Is nourished, for Instance, from Ita mother*
tails, lt la a peculiarity of the devll-
flsh, be adds, tbat. Instesd of laying
msny thousands or millions of eggs. It
normally bss only s single young one
at a birth. A baby .devilfish Is sometime*: as broad a* Ave feet nnd welgha
twenty pounda or more.
Dr. QUI adda tbst d*vtlfi*b*s mor*
about from place to pise* ln a sort of
submarine Bight, speeding tbemeeivse
•long by flap* of th* long vrtaftlk*
H WrMks lh* Wh*l* Syit***- aad
Tands to Shorten Lift.
lt Is well known that a violent fit ot
temper *ff*rt* ibe heart Instantly, and
psyrbopbysl.-lst* bave discovered the
presence .of poison In tbe blood Immediately sfter such ont burst. Tbls explain* why we feel so depressed, exhausted nnd nervous sfter sny storm
of i-esaton—worry. Jealousy or revenge
—hss swept through tbe mind. It has
left In Its wake virions mental poison
and other bsrmful secretions In tbe
brain and blood.
There Is no constitution so strong
but It will ultimately succumb to tbe
constant racking and twisting of tbe
nerv* centers caused by an uncontrolled temper. Every time yoa become angry yo-j revere-, all of the normal mentnl nnd physical pi*oces*e*.
Everything In you rebels against passion storms*, rrery mental faculty protest* nL-slnt-t their abuse
If iK-iiple only realised what hevoc
Induljrencr In bot temper playa tn
tbelr delicate nrrTons structure, if
they could only nee with the physics*
eyes the dsmsze done as they can aee
what follows In Ibe wske of * tornado.
they wonld not dare to get angry.
When the brnln cells are overheated
from a St of temper tbelr efficiency la
seriously impaired, If not absolutely
ruined. Tbe presence of the anger poison, tbe shock tn ibe nervous-system.
Is what make* Ibe'victim *o exhausted
nnd (letnoniIlu*d after Ins* of self con-
trol.—Orison Rwett Mstden In Roeceas
Mags sine.
THE BACK OF THE NECK.
WANTED
A Good Cook
to be, oar CASSEBOLMS. BOO
FIUKKS AND NAPPIXS la Ik.
bewatlfal browe aad white Lax*
. ml.urn stODrwem.
SKK OIK WD4DOW I.IHPLAT.
Bolting Hardware Co.
THE PLACE THAT
SAVES YOU MONEY
It Pays to
Buy the Best
A SNAP
THE UNDERSIGNED BOUGHT THE CORNER OF
ALMA STREET AND EVERETT AVENUE A NUMBER OF
MONTHS AGO WITH THE INTENTION OF BUILDING
A NEWSPAPER OFFICE ON THE FRONT CORNER. CIRCUMSTANCES DIVERTED THIS PURPOSE. HENCE,
THE CORNER IS FOR SALE.
THIS LOT IS 75 x 112, THE SUNNY CORNER, NEARLY FACING THE NEW LOCATION OF THE DEPOT. AND
ONLY 500 FEET FROM THE PRESENT DEPOT. RIGHT
IN THE FRONT DOOR OF THE TOWN. THE NEW SUBWAY ENTRANCE TO TOWN FROM THE NORTH WILL
BE NEAR IT. ONE BLOCK FROM TROLLEY LINE EXTENSION. LOCATION MOST CONSPICUOUS AND CONVENIENT.
THIS LOT CONTAINS. ON EVERETT SIDE FRONTAGE, A TEN-ROOM, BASEMENT AND ATTIC HOUSE,
LEAVING THE FRONT CORNER. 75 x 75, VACANT FOR
ANOTHER BUILDING. THE HOUSE IS NOW ARRANGED
IN FOUR SUITES OF HOUSEKEEPING-ROOMS.
RENTED. ^
WITH THE RENEWAL OF ACTIVITY THIS LOT
WILL RAPIDLY INCREASE IN VALUE. AS IT IS IDEALLY LOCATED FOR HOTEL. APARTMENTS, GARAGE,
OR MANY OTHER PURPOSES. IT IS NOW OFFERED
AT RESIDENCE-LOT PRICE. WILL SELL FOR CASH.
ON INSTALLMENTS. OR CONSIDER A TRADE ON
OTHER REAL ESTATE. SEE ME AT THE DAILY TIMES
OFFICE, OR ADDRESS BOX S, PALO ALTO.
H. W. SIMKINS, Owner
Ony Dr**iw*.
If you have a particular piece ot
work to do. get It don*. Don't wilt
for th* mood to strike you.
Don't dream! There ar* more precious hour* wasted In day dream*
than any of us would car* to think
about If w* counted tbem
The queer thing *bout day dream*
la that so few of them ever amount
to anything. Tbe dresrner Is oaly
ware building bis air
ao, aa * role, they bave no
practical foundation
While you sr* st work, keep yonr
mind on wbst yon sre doing, snd do
not let It wander off to what you
woold like io be doing. Only by keeping yonr mind on what yon are doing
now can yen bring lt fresh *nd'keen
to th* things yoo Ilk* doing beat wben
the ttiae for doing tbom comes. Thinking too mncb sboot even great happiness take* th* "edge" off It
Tb* beet time for day dream* 1*
after you hare gone to bed.—Nsw
York Anieriran
Tb* Better Part.
A delightful Uttle story Is told of
Prosper Metio***r. tbe Preneb author.
He was once gueat at a my*] bant,
when bsres. pbeasants snd other
game were driven before Ihe rmperor
snd his followers, and tbe servants
picked up Ibe victims of th* sport.
Among bU tbe members of tbe hunting party Pr-aper Merlme* alone bad
no trophy to display.
"How doee thl* happen?" naked
some ooe.
"Where game ls so plenty the merit
of s msrksmsn seem* to me to He ln
bitting nothing" replied Mertmee.
with grave courtesy, "so I tired between the lii-fls"
Wait*.** *n H*r**aack.
In great French bouses of days gone
by dinner wss snnouneed by the blowing of bnnting' borna, and It Is.oo fee
otd tbst at certain gala feesta the
dish** were brought In by **rv*nt* In
f*U armor mouated upon caparisoned
hara as. a practice we could only look
for diirli.g tbe reign of chivalry. Of
tb* at i-m-lanr* at dinner tbe carver aad
eerrer took pi*e^ede*nce over ail tb*
others. Tbey stood probably on each
side of their lord. The server. It may
be mention-*], wss the ofAe-er who
placed the rtlsbe* on tbe is hie
Th Fse T*t.
First Te*cb*r-You told ra to re
mlod you to panlsb Willie Thompson
this morning for Impudence. B*i***ad
Teecber—III do It tomorrow. Vm
railed leWore tbe school bosrd today
for Inaiitx-rdiiiation. I.lpplocotl's.
A aesret.
Spark*—I wonder wby It Is * woman
lets out everything yoo tell ber? Shark*
—My dear boy, a womsn ba* oaly two
rlew* of a serret-elther It is not
worth k*eplng or It Is loo good to keep.
—London Opinion.
A great man la mad* op of qaalltlB*
that meet or *ask* gnat orr-sata-*.-*-
t-nwell
Msk* It Proof Against Drafts and
Cold* In ths Head.
"When 1 was a boy.** said a doctor.
"I didn't t-e.leve In drafts. 1 thought
thst they wbo Imputed rnld* to drafts
were Franks. But one November
nlgbt at a roacert 1 fatt all tb* evening a atrong draft on tbe back of my
neck. It was *o *trong II resembled a
su. lion pomp. 'Now.* aald I to my*
self, -we'll aee If tbla draft will give
yours truly a cold.'"
He Rbuddered.
"Por a week," be said, fl waa laid
up with so vile a cold that I couldn't
breathe s*r* with my mouth open
And now 1 am satisfied tbst nine out
of i'» - ry ten colds are solely doe to a
draft on tbe back of the neck.
"I know now to prevent euch colds.
Bene* 1 msy practically aay tbat I
know bow to prevent all colds. It le a
fact that none of my patients, thank*
to my method, know what a cold ta.
•Tiny ii-urti from me to do this—to
bathe tbe heck of the neck every
morning In .'old water. Thus the spot
becom**' bsrdeaed. It becomes draft
proof.
''And when a new patient, peculiarly
sensitive to i olds, visits me, my peculiar treatment 1* to blow on th* back
of his neck with a bellow* for several
day* ln su<vi**al<-n. The tiellows. In
conjunction wltb tbe ley douche, free*
blm from all future susceptibility
Thenceforth his winter* peas without
thst fadrrtd winter pest, a bad coid."-
New Orleans Times-Da-a-orrat.
C«l*r*d Preacher's Taat.
A colored man lo Atlanta. Oa.. la a
prrarne-r on Sundays and a barber oa
week days. One of bis cast omen
rnaki-a It a rule to be flrst to the cbalr
ne Monday morning, wben be Is but*
of being entenalned by a resume of
"tTncle Itasius'" Sunday dissertation.
At night tbe family always looksd for
the latest from tbe colored brother
This waa one of hla recent effusions: '
"Yasterdsy I took for my text 'Clean*
line** am next lo godliness.' and I
dun reach my climax aid' die argument: 'Now, what day foil..** San-
day 1 Why.' Monday. Hi n/tr 1*>
waah day tn all well reg'laied faav
blle* Monday cornea nex' Io Sunday: so, my bredden. thst settles lt
thst tb* word* of my tax* am true.
**C*leantti-«as in nex' to godliness.""*
-Chicago Uncord -Herald.
Rich, deep, level, sandy loam Alfalfa. Fruit. Berry and Vineyard
Land, Including Citrus Fruits, at
HEAD OF FAMOUS TURLOCK Ia\-
HIQATION DISTRICT, Stanislaus
county, about one hundred mile*
eesterly trom San Francisco, between two railroads and on proposed electric tine; elevation 173
feet, abaolntely no alkali, waterlog or malaria.
The I,. M. Hickman ranch of II,-
000 acre* la tea and twenty acre
tracts, with FREE water rlght-
ditche* to each tract, abundance ef
water at 80c per acre a year. Tartan,
one-fourth cash, balance ooe to four
year*. Por farther Informstiss,
price* snd FREE illustrated booklet, map*, etc., writ* L. W- JJUT*
PERSON REALTY COMUANT. 360
Market atreet, 8. F.. or a** oar lo
cal agent,
W. A.
Whitmer
Kmeraoa street, rale an,.
When You Are In
San Francisco
""-st* GO* *•
Valencia Theatre
Taaaphons MsrSrt ir
Take s Vskted* Strvel ear to lh* dear. J*>
Ar* ■last** nearer Third ss-dMar.ri t buttl-
erases tieimx. Ut ih* fiaeit Th**t** Wis* w*s
as* lb* bmtmmt in Aumnc*.
. . AND . .
Tf«t*'s impUi menrr s**t5 Uai'i a*r* n-tac
s lw**<ss ***** as saa.
YOU WONT BE SORRY
GOl GO! GO!
Tee Mush Quisi.
On one occasion the bustling and
energetic archbishop of York. Dr.
\ts- isrnii, wrote to the vicar In an
outlying village suggesting tbat be
should lend his church for tbe purpose
of gliing the clergy of tb* dlatrict a
"quiet day** for meditation and fraternal reunion. The witty vicar of thai
sleepy hamlet In the wold* promptly
replied:
My Uear Lord Arebblahop—Ycmr very
hind i-uar lo I,and flu! what lb* p*opl*
In tbls vtlt**** waat most ta their aptrttual
Uf* Is not * "*ul*t day.'' but an aartb-
*uaas.
—London Standard.
An Appeal For Mercy.
"Joil-.-"." asld thr prisoner, "I sup-
poe* you're going to aoek ro*."
"You ar* a imMtusl nffender." replied tbe judge: "were caught with the
stolen goods, and tbe court will have
to do Its painful doty.**
"J don't want in n-rem unreasonable,'*
replied tbe prisoner. "I don't mind a
long sentence I'm used to IL Bat
say, Judge, rut oot tbe lecture that
usually goe* wtlh It, won't yoo.**—
Philadelphia ledger.
Th* Brut*.
~*T***, tbt* room Is dark, damp aad
positively uninhabitable. It Is sup-
ptted for your wife's mo!her, If she be*
-Sbe bss.
Traveler.
ill tske tbe flat."
An Old Tim*r.
"He's sa otd newspsper msn.*'
"A I-out bow old--
•Well, be can remember when they
only Issued extras wben eomethlag
tatsppened."--Louisville Courier*Journal. ..
fi-ificMi-nauraiiEitfifa
SAN FRANCISCO
"CHRONICLE*
«**• Iw<*'i eemmmmm a** mo-7 -SiJtL
zzrc^^ijyrzz^ss
H^"^*L?eVWS.s--ir
. II . B— Baser .seas, ra. tmmw. tt.
S|£S*.^C*SS.!SeT«*
KAt SUBSO-JPTrOK MTB
Ma Weeklj ""hrmride
1** vt-ry baas weekly bow**bb**s*
$1.50 a Yor
la **aStsg I* rmur eskssjsleU**,
aCH.de TO UNO,
See Praaelsee, CaL
a>arope la lea* than ooe-ft-eoth *■
larg* as Asa*.
"Fn.alst.ed Rooms" window
at Times ottce, te
Radiotherapy for prostate cancer: is it ‘what you do’ or ‘the way that you do it’? A UK perspective on technique and quality assurance
No full textAims:
The treatment of prostate cancer has evolved markedly over the last 40 years, including radiotherapy, notably with escalated dose and targeting. However, the optimal treatment for localised disease has not been established in comparative randomised trials. The aim of this article is to describe the history of prostate radiotherapy trials, including their quality assurance processes, and to compare these with the ProtecT trial.
Materials and methods:
The UK ProtecT randomised trial compares external beam conformal radiotherapy, surgery and active monitoring for clinically localised prostate cancer and will report on the primary outcome (disease-specific mortality) in 2016 following recruitment between 1999 and 2009. The embedded quality assurance programme consists of on-site machine dosimetry at the nine trial centres, a retrospective review of outlining and adherence to dose constraints based on the trial protocol in 54 participants (randomly selected, around 10% of the total randomised to radiotherapy, n = 545). These quality assurance processes and results were compared with prostate radiotherapy trials of a comparable era.
Results:
There has been an increasingly sophisticated quality assurance programme in UK prostate radiotherapy trials over the last 15 years, reflecting dose escalation and treatment complexity. In ProtecT, machine dosimetry results were comparable between trial centres and with the UK RT01 trial. The outlining review showed that most deviations were clinically acceptable, although three (1.4%) may have been of clinical significance and were related to outlining of the prostate. Seminal vesicle outlining varied, possibly due to several prostate trials running concurrently with different protocols. Adherence to dose constraints in ProtecT was considered acceptable, with 80% of randomised participants having two or less deviations and planning target volume coverage was excellent.
Conclusion:
The ProtecT trial quality assurance results were satisfactory and comparable with trials of its era. Future trials should aim to standardise treatment protocols and quality assurance programmes where possible to reduce complexities for centres involved in multiple trials
Functional and quality of life outcomes of localised prostate cancer treatments (prostate testing for cancer and treatment [ProtecT] study)
No full textObjective
To investigate the functional and quality of life (QoL) outcomes of treatments for localised prostate cancer and inform treatment decision-making.
Patients and Methods
Men aged 50–69 years diagnosed with localised prostate cancer by prostate-specific antigen testing and biopsies at nine UK centres in the Prostate Testing for Cancer and Treatment (ProtecT) trial were randomised to, or chose one of, three treatments. Of 2565 participants, 1135 men received active monitoring (AM), 750 a radical prostatectomy (RP), 603 external-beam radiotherapy (EBRT) with concurrent androgen-deprivation therapy (ADT) and 77 low-dose-rate brachytherapy (BT, not a randomised treatment). Patient-reported outcome measures (PROMs) completed annually for 6 years were analysed by initial treatment and censored for subsequent treatments. Mixed effects models were adjusted for baseline characteristics using propensity scores.
Results
Treatment-received analyses revealed different impacts of treatments over 6 years. Men remaining on AM experienced gradual declines in sexual and urinary function with age (e.g., increases in erectile dysfunction from 35% of men at baseline to 53% at 6 years and nocturia similarly from 20% to 38%). Radical treatment impacts were immediate and continued over 6 years. After RP, 95% of men reported erectile dysfunction persisting for 85% at 6 years, and after EBRT this was reported by 69% and 74%, respectively (P < 0.001 compared with AM). After RP, 36% of men reported urinary leakage requiring at least 1 pad/day, persisting for 20% at 6 years, compared with no change in men receiving EBRT or AM (P < 0.001). Worse bowel function and bother (e.g., bloody stools 6% at 6 years and faecal incontinence 10%) was experienced by men after EBRT than after RP or AM (P < 0.001) with lesser effects after BT. No treatment affected mental or physical QoL.
Conclusion
Treatment decision-making for localised prostate cancer can be informed by these 6-year functional and QoL outcomes
