423 research outputs found
The abundance and activity of aerobic methane oxidizing bacteria in soils
No full textAuthor Margaretha Buchner, BScKurzfasssung in deutscher SpracheMasterarbeit University Innsbruck 201
The abundance and activity of aerobic methane oxidizing bacteria in soils
No full textAuthor Margaretha Buchner, BScKurzfasssung in deutscher SpracheMasterarbeit University Innsbruck 201
Dateninfrastrukturen für die Gesundheitsforschung: Ethische Rahmenbedingungen und rechtliche Umsetzung
No full textThe role of data infrastructures for health research is not limited to acting as a service or interface for data exchange between data producers and data users. Rather, the infrastructure itself is an actor in the process of data sharing and therefore also bears responsibility for this process. This applies first of all to the lawfulness of personal data processing. If data processing is based on the consent of the data subject, the infrastructure must also ensure that all data processing is covered by this consent. If the data processing is based on a statutory basis, the infrastructure must ensure the highest possible level of data protection, in particular through technical and organizational measures. In addition, the infrastructure is also responsible for implementing the rights of data subjects, such as the right to information, rectification or erasure of data, and dealing with incidental or additional findings. The question of how researchers regard their involvement in infrastructure projects and how private companies should be involved in such projects must be based on the principle of public welfare. This is accompanied by the obligation of infrastructures to take into account the principles of participation, transparency, and scientific communication as far as possible. Observing all these ethical and legal aspects is especially important because only by doing so can the trust of all stakeholders be established and thus the central basis for the successful construction and operation of data infrastructures be provided
Stress and heart disease in women
No full textPsychosocial aspects of heart diseases have usually been studied in predominantly male patients. Growing evidence shows that the results of these studies cannot simply be generalized to women. The research on associations between psychosocial factors and heart disease, especially coronary heart disease, in women is therefore summarized in a literature review. The literature shows that women are subject to adverse cardiac effects of stress and chronic negative affects in a similar way as men. However, in women the relevant sources of distress are often found in other areas, i.e., in the family and household environment, and less often at the workplace. Especially for working mothers, the combination of professional and household work constitutes a considerable stressor. Stress is also perceived differently in men and women, and it leads to different physiological reactions. One striking example is the recently described "stress cardiomyopathy", an acute, life-threatening illness, which is often triggered by sudden emotional distress and can mainly be found in women. Women with heart disease report more psychological distress in response to their illness than men. As in men, depressive symptoms may negatively impact prognosis. Nevertheless, women receive less rehabilitation treatment than men and also benefit less from common psychological offerings. There is some evidence that women need specially developed psychosocial interventions and should not simply be treated in predominantly male stress-management groups. In clinical practice, gender-specific stressors and accompanying psychological symptoms should be discussed with the female heart patient. If needed, she should receive individualized psychosomatic treatment
Figs 19–22 in Depressariidae (Lepidoptera) of the Russian Altai Mountains: new species, new records and updated checklist
No full textFigs 19–22. Exaeretia mongolicella (Christoph, 1882). 19–20 – habitus: 19– Russia, Tuva, Ak-Chol, Ak-chol lake, 3.vii.2015, J. Šumpich leg. (NMPC); 20 – Russia, Vladivostok, vi.1994, Kuznetsov leg. (RCGD). 21 – male genitalia, Russia, Primorsky krai, Ussuri, Kazakevich, 1908, T. Walsingham leg. (MGAB). 22 – female genitalia, Mongolia, Central Aimak, Kerulen, 24.viii.1965, Z. Kaszab leg. (MNHN) (museum id. EL62902 with slide number MNHN-EL41).Published as part of Buchner, Peter & Šumpich, Jan, 2020, Depressariidae (Lepidoptera) of the Russian Altai Mountains: new species, new records and updated checklist, pp. 201-244 in Acta Entomologica Musei Nationalis Pragae 60 (1) on page 207, DOI: 10.37520/aemnp.2020.013, http://zenodo.org/record/387951
It's worth cleaning – The examination of the female taper could identify a particular cause of trunnionosis at revision 16 years after total hip arthroplasty
No full textAdverse reaction to metal debris (ARMD) is an issue in metal-on-metal (MoM) total hip replacements (THR). It mainly affects large-head MoM THR, whereas 28–32 mm MoM pairings are associated with low long-term revision rates. However, the bearing surface is not necessarily the only cause of metal debris. This report documents with advanced analysis of the retrievals a particular cause of trunnionosis in late failure of a small diameter MoM THR and illustrates the importance of cleaning of the taper when seating the head in THR. A 65-year-old patient was revised due to ARMD 16 years after small diameter MoM THR. Debridement and exchange of the inlay and the head had been performed through an anterior approach. While the cup and the outer surface of the head were accessible to direct analysis by an optical coordinate measuring machine, the female taper had to be analysed indirectly by measuring an imprint. Wear from the cup and the head was within expected low ranges. The analysis of the female taper identified bone fragments, which contributed to trunnionosis. Failure due to ARMD after MoM THR is not necessarily caused by the bearing, but can be due to trunnionosis. Bone fragments within the taper contact in this case highlight the importance of meticulous cleaning of the taper before seating the head, to avoid trunnionosis
andycasey/ads: 0.12.7
No full textRemoves trailing slash in API end points, which recently caused queries to broke (@JohannesBuchner)Andy Casey, Vladimir Sudilovsky, Jonny Elliott, Steven Murray, Miguel de Val-Borro, Christoph Deil, Michael Maier, Geert Barentsen, astrowizicist, Dan Foreman-Mackey, Timothy Gebhard, Sergey Koposov, Rui Xue, Roman Chyla, Mike Boyle, Keaton Bell, Johannes Buchner, James Guillochon, Erik Tollerud, & Aram Panasenco. (2024). andycasey/ads: 0.12.7 (0.12.7). Zenodo. https://doi.org/10.5281/zenodo.1454793
Verzeichnis der gedruckten Briefe deutscher Autoren des 17. Jahrhunderts, Teil 1: Drucke zwischen 1600 und 1750, A-F
No full textBeträge über u.a.: Kaspar Abel, Johann Georg Abicht, Johann Arndt, Gottfried Arnold, Friedrich Balduin, Balthasar Bebel, Christian Beckmann, Johann Christoph Beckmann, Bernhard Anton Bertram, August Beyer, Peter Adolph Boysen, August Buchner, Johann Heinrich Callenberg, Abraham Calov, Christoph Cellarius, August Hermann Francke, Gotthelf August Francke, Reinhold Franckenberge
Über Grenzen von Recht und von Juristen: Abschiedsvorlesung und Reden anlässlich der Verabschiedung von Prof. Dr. Wilhelm Dütz am 17. Januar 2002
No full textAbschiedsvorlesung und Reden anlässlich der Verabschiedung von Prof. Dr. Wilhelm Dütz am 17. Januar 2002 [Vedder, Christoph: Begrüßung und Würdigung ; Bottke, Wilfried: Grußwort der Universitätsleitung ; Buchner, Herbert: Die wissenschaftliche Arbeit von Wilhelm Dütz ; Dütz, Wilhelm: Über Grenzen von Recht und Juristen : Erfahrungen und Erinnerungen
Free energy landscapes for dendrimer-like DNAs via neural networks
No full textFree energy landscapes for dendrimer-like DNAs
via neural networks
Florian Buchner 1 , Clemens Jochum 1 , Gerhard Kahl 2 , Andreas
Singraber 1,3 , Christoph Dellago 3
1 Institute
for Theoretical Physics, TU Wien, Wiedner Hauptstraße 8-10, A-1040 Vienna, Austria
for Theoretical Physics and Center for Computational Material Science (CMS), TU
Wien, Wiedner Hauptstraße 8-10, A-1040 Vienna, Austria
3 Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria
e-mail: [email protected]
2 Institute
We consider dendrimer-like DNAs (DL-DNAs, as thoroughly discussed
in the contribution by Natasa Adzić) [1] which we model within a monomeric
bead-spring model: the DNA base-pairs are modeled by charged monomers
and their interactions are chosen to mimic the equilibrium properties of
DNA correctly [2].
The huge number of internal degrees of freedom of this model drastically
limits its use in simulations of concentrated solutions: even with the use of
optimized code packages (such as GROMACS, ESPResSo MD, LAMMPS or
oxDNA) simulations of ensembles of typically 50 (or at most 100 DL-DNAs)
are within reach.
This limitation calls for suitable strategies to cope with this problem:
one standard route is the use of effective potentials obtained by suitably
integrating over the degrees of freedom of the monomeric entities. Here we
represent such effective potentials with artificial neural networks,relying on
their capacity to accurately reproduce complex high-dimensional functions.
Once properly trained with reference data calculated via the monomeric
model, neural networks provide access to effective potential energies and
analytically derived forces, which can then be used in molecular dynamics
simulations. The latter ones can be performed for our system at a fraction
of computational costs as compared to the simulations of the monomeric
model. In this contribution we report about first results of these investiga-
tions. Recently, Luo and his co-workers at Cornell University synthesized
dendrimer-like DNA (DL-DNA) via enzymatic ligation of Y-shaped DNA
building blocks.
[1] C. Jochum, N. Adzić, E. Stiakakis, T. L. Derrien, D. Luo, G. Kahl, and C. N. Likos, Nanoscale,
11, 1604-1617, (2019)
[2] A. Wynveen and C. N. Likos, Soft Matter, 6, 163-171, (2009
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