1,720,953 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
A promising stem cells strategy to correct corneal defects due to a unique homozygous missense mutation p.R311K in the Tp63 gene causing dominant EEC syndrome.
No full textBackground Ectrodactyly - Ectodermal dysplasia - Clefting (EEC) syndrome is a rare autosomal dominant inherited disease. To date, approximately 40 different Tp63 mutations have been identified, all reported as heterozygous mutations. There is no definitive cure available to counteract and resolve the progressive corneal degeneration resulted from the premature ageing of limbal epithelial stem cells (LESC). However, oral mucosal epithelial stem cells (OMESCs) represent a valid alternative capable of regenerating the corneal epithelium and provide an attractive therapeutic avenue. Our group has recently discovered R311K-∆Np63 mutation, a unique homozygous mutation causing EEC syndrome with a mosaic pattern. The survival of the patient was intriguing as homozygous dominant mutations are lethal. Unlike other EEC mutations, R311K-∆Np63 keeps the binding ability to DNA that can make it a milder mutation if raised in heterozygous form. Aim of research The research focus on studying the R311K-∆Np63 mutation, its effect on protein expression, its transactivation activity and comparing it with other heterozygous mutations (R311G-, R304Q- and R279H∆Np63). The final goal of the research was to find a therapy for the ocular impairment of our EEC case by isolating and expanding ex vivo the heterozygous epithelial stem cells, identified by means of DNA and RNA characterization, from OMESCs biopsy. Cultured autologous OMESCs can represent an effective treatment to reconstruct the ocular surface and partially restore the ocular function in our case. Materials and methods R311K-∆Np63 mutation was studied by testing their protein expression in transfected HEK293T cells by western blot and by measuring their transactivation activity by Luciferase reporter assay on K14 promoter, as it contains p63 binding sites and because the protein expression is ∆Νp63 dependent. Individual cells were isolated from a primary cell culture obtained of OMESCs biopsy from the patient by clonal analysis, expanded ex vivo to be used for CFE analysis and molecular characterization. DNA was extracted with Chelex resin, purified by ethanol precipitation and amplified by PCR to be sequenced by Sanger Method. RNA was extracted by Triazol, purified from possible DNA contaminants by RNAeasy (Biorad microkit), quantified, tested for integrity and quality by agarose gel electrophoresis, reverse-transcribed to cDNA, and then amplified to be analyzed by absolute real time PCR. Results The expression of R311K∆Np63 is increased in ectopic system of expression and Luciferase reporter assay revealed a severe inhibition in the transactivation activity of the K14 promoter in case of homozygously mimicking conditions in transfected HEK293T cells and a significant less severe inhibition in the transactivation activity of the same promoter in heterozygously mimicking transfected cells. Only 20% of isolated single cells of the primary cell culture of the OMESCs biopsy were able to grow into full colonies. These colonies were found heterozygous for the mutation R311K∆Np63. CFE assay for all colonies revealed the presence of 24 holoclones that, when analyzed by qPCR analysis, showed similar ∆Np63α expression level to LESC (previously used cells to successively correct limbal stem cell deficiency- LSCD) suggesting the possibility to use these holoclones to correct LSCD in our case. Conclusion Cultured autologous OMESCs, obtained by selected R311K-N∆p63 heterozygous stem cells, could be effective as personalized therapy to reconstruct the ocular surface of this particular and unique case of EEC syndrome
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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