1,721,058 research outputs found

    Prophylactic C-Pap versus Oxygen Support with Venturi Mask in COPD Patients Undergoing Lung Lobectomy: A Pilot StudyElisabetta Gualtieri, Md1; Adducci, Enrica; Md, ; Primieri, Paolo; Md, ; Galla, Amerigo; Md, ; Chiappetta, Marco; Md, ; Granone, Perluigi; 1Università Cattolica del Sacro Cuore, Md1.; Roma, ; Italy, ; 2ieo, ; Milano

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    Objective: Evaluating the feasibility and the efficacy of prophylactic post-operative Continuous Positive Air Pressure (C-PAP) administration in a thoracic surgery unit, compared to oxygen support with Venturi mask in term of Oxygen Partial Pressure/Oxygen concentration in breathed air (PaO2/FiO2) in COPD patients undergoing lung lobectomy. Materials and Methods: Respiratory morbidity after lung resection may occur in 15-20% of the patients, and C-PAP is an effective therapy. It is usually administered in Intensive Care Unit (ICU), while its prophylactic use is not well investigated and it isn't reported in a thoracic ward. We enrolled 19 patients with stage II COPD according GOLD score underwent lung lobectomy in a prospective randomized trial. Group A (10 patients) received in post-operative (PO) a FiO2 percentage to obtain a saturation > 95% with a Venturi mask, while group B (9 patients) received in PO a prophylactic C-PAP to obtain a saturation > 95% with a facial mask and 7,5 mmHg valve for two hours after surgery and then 2 hours every 8 hours for the first and the second post-operative day. PaO2 evaluation was made during the treatment 2 hours after surgery (T1) and in the first PO day (T2) and in FiO2 21% in the second PO day(T3). The two groups received the same treatment in terms of surgical access and resection (lateral thoracotomy and lobectomy), general anesthesia , PO physiotherapy and analgesic therapy. Results: No differences in terms of general characteristics, comorbidities, respiratory function (FEV1, FVC, DLCO, PaO2/FiO2), heart rate, blood pressure, and surgery time were noted between the two groups. PaO2/FiO2 was 379,5 ± 26,7 vs 415,3 ± 102,2 at T1 (p= 0,6), 357 ± 105 vs 310 ± 127 at T2 (p=0,4) and 323,5 ± 62,9 vs 315,2 ± 33,1 at T3 (p=0,4). We documented respiratory complications in 4 patients in the group A and in 3 patients in the group B. In group A one patients had acute pulmonary oedema needed orotracheal intubation and ICU transfer in first PO day, while the other three patients showed desaturation < 70 % during the first PO day. Three patients in group B had the x-ray chest showed microatelectasis in first post-operative day with resolution the next day. In particular PaO2/FiO2 in complicated patients in group A and in group B was 195 ± 38,5 vs 435,2 ± 129,8 (p=0,019) at T1; 166,3 ± 33 vs 371,3 ± 166,9 at T2 (p=0,022) and 253 ± 33,4 vs 313,6 ± 33,6 at T3 (p= 0,07) respectively. Finally, there were not differences between the two groups in term of prolonged air leak (0 patients in group A and B both), hospital stay and satisfaction about the treatment. Conclusion: Our initial findings show the feasibility of a C-PAP prophylactic program in a thoracic surgery unit and suggest the C-PAP prophylactic role to avoid desaturation and pulmonary oedema and the C-PAP curative role in atelectasis after lung lobectomy in COPD patients, as is notable in a significantly better PaO2/FiO2 in group B complicated patients than in group A complicated patients. We studied 19 patients with stage II COPD according GOLD score undergoing lung lobectomy. Our initial findings show the C-PAP prophylactic role to avoid desaturation and pulmonary oedema and the C-PAP curative role in atelectasis after lung lobectomy in COPD patients a significantly better PaO2/FiO2 in group B complicated patients than in group A complicated patient

    High incidence of vascular complication after computed tomography guided lung biopsy : what's matter , the patient or the tecnique?

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    We read with interest the article of Anzidei on a predicitive score of complication after lung computed tomography -guided biopsy . We think there is a percentage of complications especially pneumotohorax which are impossible to avoid , but it would be useful to predict in which cases they occur with hiogh frequency

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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