9,175 research outputs found
Teaching Italian LS for university students in China: the case of the ZYU
No full textreservedCon gli scambi e la cooperazione sempre più stretti tra l'Italia e la Cina, la politica educativa delle lingue straniere della Cina sempre più rivolta verso l'esterno, il numero di studenti cinesi che imparano l'italiano è aumentato notevolmente. L'obiettivo di questa tesi è studiare l'insegnamento dell'italiano LS agli studenti universitari cinesi in Cina. Pertanto, la presente tesi ha introdotto: alcune teorie fondamentali glottodidattiche, l'evoluzione della politica educativa cinese delle lingue straniere e lo sviluppo dell'insegnamento della lingua italiana in Cina, inoltre indaga e analizza l'Università ZYU come caso. In base ai risultati del sondaggio, sono state fornite alcune proposte che potrebbero essere utili
Accumulation of butyltin compounds in the pantropical spotted dolphin, Stenella attenuate, from the coasts of Taiwan.
No full textTemporal-spatial rupture process of the 1999 Chi-Chi earthquake from IRIS and GEOSCOPE long-period waveform data using aftershocks as empirical Green’s functions
No full textThe Impact of ERP Implementation in Cosmetic Industry- A Case Study of LS Inc.
No full textFrom 80 to 90 decade Taiwan Enterprises between small & medium had been raid development thus they should face the intense competition of cross strait. Hence we must rely on Information Technology for proceeding control system to enhance enterprises competitiveness.
LS Company is a professional OEM of Cosmetics Industry, to meet business growing badly & produce demand so LS had been switched to Overseas company since 5 years ago, so it would cause the fail of arrangement , communication lagged, working procedure unexpected, lousy efficiency several issues. So LS Co. deeply consider whether they should establish an internal Standard Operation Procedure (SOP) & reduce accounting mistakes percentage 2 issues.
According to Dr. Jen-Her-Wu Information Management \ue2Business Innovation & Value Creation \ue2the internal working procedure of enterprises including main & aid produce, main procedures including: inquiry, take order, purchasing, stock arrangement, account payable, producing, shipping, account receivable; as to aid procedure which can assist main procedure to proceed properly. ERP is information technology system, which is cable to organize several procedures together., thus build up Standard Operation Procedure (SOP) system then it will reduce the mistakes between each dept. communication, no more duplicated working proceeding & resources wasted several points. Thus they can fix the competition superiority, in the meantime it can be integrated all messages between each dept. so they are capable to control the newest status. Hence LS made decision of Implementation of ERP for proceeding Co. resources integration and system adjustment.
The purpose of investigation LS Co. implementation of ERP, whether it would improve the co. management or not? Thus I will make comparison between Implementation of ERP Before & After, evaluation the proceeding mistakes & management efficiency
Remission, Relapse, and Metastasis/Death of Small Hepatocellular Carcinoma Treated with Percutaneous Ethanol Injection
No full textA mixture of dioxins, furans, and non-ortho PCBs based upon consensus toxic equivalency factors produces dioxin-like reproductive effects
No full textSympathetic nerve sprouting, electrical remodeling, and increased vulnerability to ventricular fibrillation in hypercholesterolemic rabbits.
No full textLS-MolGen: Ligand-and-Structure Dual-Driven Deep Reinforcement Learning for Target-Specific Molecular Generation Improves Binding Affinity and Novelty
No full textDeep learning-based molecular generative models have
garnered considerable
interest in the field of de novo drug design. However, most extant
models focus on either ligand-based or structure-based strategies,
thereby failing to effectively harness the combined knowledge derived
from both ligands and the structure of the binding target. In this
article, we introduce LS-MolGen, a novel ligand and structure-integrated
molecular generative model. This model synergistically combines representation
learning, transfer learning, and reinforcement learning. The targeted
knowledge assimilation from transfer learning, coupled with an advanced
exploration strategy in reinforcement learning, empowers LS-MolGen
to efficiently generate novel and high-affinity molecules efficiently.
The comparable performance of our model is affirmed through multiple
evaluations, including EGFR, DRD3, CDK2, AA2AR, ADRB2, and a dedicated
case study of inhibitor design for SARS-CoV-2 Mpro. The results indicate
that LS-MolGen performs better than other ligand-based or structure-based
generative models in de novo designing promising compounds with novel
scaffolds and high binding affinity. This proof-of-concept study signifies
the potential of our ligand- and structure-based generative model,
LS-MolGen, as a promising new tool for target-specific molecular generation
and drug design
A population-based study on the association between metabolic syndrome and hepatitis B/C virus infection (Keelung Community-based Integrated Screening Study No. 10)
No full text- …
