27,544 research outputs found
The radiology of paragangliomas of the skull base
Paragangliomas are rare tumors of unknown etiology arising from paraganglionic cells in relation to nerves and blood vessels. They are slow growing benign tumors capable of producing paraneoplastic syndromes due to production of hormones. Malignant transformation is extremely rare. The cornerstone of diagnosis of these tumors in the skull base region is imaging. Biopsy is not appropriate as these tumors are extremely vascular and bleed profusely. Four types of paragangliomas are described in the skull base region including glomus tympanicum, glomus jugulare, glomus vagale and carotid body tumors. It is important to differentiate the four types of tumors in order to decide the most appropriate surgical approach for the excision of the tumors. Differences in expansion and invasion may be delineated radiologically and hence morbidity with respect to involvement of the lower cranial nerves may be predicted. It is also possible to decide the best time for surgical intervention in those tumors where a 'wait and watch' policy is exercised. A radiological staging classification is also possible that may help decide the most appropriate modality of management. We describe here, with clinical examples, the characteristic imaging features of the four types of paragangliomas using high resolution Computerized Tomographie scanning (HRCT) and Magnetic Resonance Imaging techniques (MRI).</p
Chronic cerebrospinal fluid leak into skull base causing intramedullary osteolysis
We present the rare case of a 74-year-old woman with extensive intramedullary osteolysis of the petroclival skull base straddling both sides of the basi-occiput and basi-sphenoid. She presented with clinical features of recurrent spontaneous cerebrospinal fluid (CSF) otorrhoea despite three previous attempts at repair of the CSF leak. Recent advances in imaging techniques enable accurate radiological diagnosis of skull base lesions. We performed T1- and T2-weighted magnetic resonance (MR) images, a fluid attenuated inversion recovery (FLAIR) sequence MR, and a diffusion scan to study the characteristics of the skull base pathology. This revealed extensive osteolysis, with cystic spaces within the clivus and the petrous pyramid extending also to the basi-occiput. The leak was sealed using the technique of subtotal petrosectomy with obliteration of the eustachian tube and blind pit closure of the ear canal. The patient has been followed up for six months with no recurrence of symptoms.</p
Health-Care Providers' Preparedness for H1N1/09 Influenza Prevention and Treatment in Dar es Salaam, Tanzania.
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In Tanzania, the first case of H1N1/09 influenza was reported in September 2009. By March 2010, the reported number of cases was 770 with one death. Due to shortage of qualified human resources, essential medicines and laboratory supplies in health facilities, it was not known how well health-care providers in the country were prepared to deal with the pandemic. The study was conducted from December 2009 to May 2010 in public hospitals and private community pharmacies in Dar es Salaam, Tanzania. Fifty-three prescribers and 200 dispensers were interviewed to assess their knowledge on the prevention and treatment of H1N1/09 influenza, and dissemination of correct information to the public regarding the pandemic. Most participants had inadequate knowledge on the transmission, prevention and management of H1N1/09 influenza. The majority of prescribers knew neither the antiviral drugs recommended for the treatment of H1N1 influenza (64%) nor their adverse effects (92.5%). The drug dispensers' knowledge was also inadequate regarding the transmission, prevention and treatment of H1N1/09 influenza. Forty-one (20.5%) salespersons without formal training in pharmaceutical or medical sciences were found dispensing and supervising the pharmacies. Most participants had misconceptions on how H1N1/09 virus was transmitted. The results of the study revealed gaps in the knowledge of the health-care providers on the prevention and treatment of H1N1/09 influenza infection. This indicates the need for strengthening of health-care systems and provision of continuing education and professional development for health-care providers on new and re-emerging diseases in the community.\u
Studies in design and development of stomach specific drug delivery system using various approaches
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Informetrics on M. N. Srinivas
M. N. Srinivas, the well known sociologist is widely recognised as architect of modern Indian sociology and social anthropology. His publications have been analysed by year, domain, authorship pattern, channels of communication used. Keywords, etc. The results indicate that the papers published by him are of a nature that qualify him to be a 'role model' for the younger generations to emulate.
By the end of 1995, Srinivas had to his credit 144 papers which, included 33 broad papers in sociology and anthropology; 18 papers in social change; 28 papers in village studies; 12 papers on religion; 17 papers on caste and 36 papers of general popular interest. The periods 1958-61 and 1974-77, when Srinivas was 38-41 and 58-61 years old. were his most productive periods with highest publication activity
Teatral'naja dejatel'nost' N, Ja. Agnivceva v Berline 20-ch godov
The article focuses on N. Ya. Agnivtsev's theatre work in Berlin in the early 1920s as author of sketches and founder of the cabaret "Vanka-Vstanka"
Numerical investigation of localized exact solutions of the Navier-Stokes equations in pipe flow
The edge state solution in pipe flow at Re=2200 is calculated numerically. The solution has the form of spatially localized puff-like structure drifting downstream. In the moving frame it is represented by a steady average flow and time-periodic pulsation flow. It is shown, that the Kelvin-Helmholtz instability mechanism is not valid for pulsation generation in the edge state flow
RYDBERG SERIES IN N V
Author Institution: U.S. Naval Research Laboratory“Three complete Rydberg series, and , extending to the ionization limit have been observed in the spectrum on N V excited in a low pressure, high voltage condensed capillary discharge. An ionization limit of ev. Has been determined from these Ions series for N V.
Main and Interactive Effects of Diabetes Distress and Stress from Life Events on Overall Psychological Distress
This study sought to extend previous research by examining rates of three different types of diabetes distress, and whether stress from life events amplified the association between diabetes distress and overall psychological distress in a community-based sample of 119 middle-aged and older adults with type 2 diabetes. Consistent with past research, individuals experienced a moderate level of diabetes distress. However, only some types of diabetes distress were associated with depressive symptoms, independent of stressful life events, whereas all types of diabetes distress were only related to anxious symptoms when stress from life events was also high.This has not been published yet (just accepted). I do not know if there is an embargo period for this journal.Peer reviewe
The Author as the Antihero
В статье соотносятся такие понятия, как автор и антигерой. На примере литературной группировки «проклятых поэтов» исследуется эстетическая проблема сосуществования добра и зла в одном человеке - автора как творца и автора как падшего ангела, бунтаря против закона, установленного Творцом.The article correlates the notions of the author and the antihero. With reference to the literary group of the Cursed Poets, the article studies the aesthetic problem of the coexistence of good and evil within one person, the author as a creator and the author as a fallen angel, rebelling against the law set down by the Creator
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