460 research outputs found

    Impact of cardiac rehabilitation on ventricular repolarization indexes in patients with rheumatid arthritis

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    Objective: Abnormalities in ventricular repolarization (VR) parameters have been associated with sudden cardiac death (SCD) in patients with rheumatoid arthritis (RA). The benefits of cardiac rehabilitation (CR) in patients with RA are well recognized. We aimed to assess its impact on VR indexes in patients with RA. Methods: This study included 45 patients with RA (36 female, age 58 +/- 5.5 years) and 50 age- and sex-matched otherwise healthy controls. Baseline electrocardiogram (ECG) recordings were used to compare VR parameters such as maximum and minimum QT intervals, and corrected, and dispersion (QTmax, QTmin, cQTmax, cQTmin, QTd, cQTd, respectively), JT and cJT intervals, Tp-e and cTp-e intervals, and Tp-e/QT and Tp-e/cQT ratios in patients with RA and healthy individuals. The effects of 6-week CR in patients with RA were also evaluated by comparing pre- and post-CR ECG5, exercise tolerance test (MET and VO2max) and RA characteristics (C-reactive protein (CRP), Disease Activity Score 28 (DAS28) and Health Assessment Questionnaire(HAQ)). Results: In comparison with the healthy individuals, the patients with RA had significantly higher cQTmax and QTmin intervals, QTd, cQTd, Tp-e and cTp-e intervals, and Tp-e/QT and Tp-e/cQT ratios. At the end of CR, all VR indexes (p < 005), except QTd, were significantly decreased as did the results for CRP, DAS28, and HAQ (all p < 0.05), and MET and VO2max (p < 0.05 for both) were significantly increased in patients with RA. Conclusions: CR may provide an improvement in the majority of VR indexes which are related with ventricular arrhythmia and SCD in patients with RA. Changes in ETT parameters and RA characteristics may contribute to improvement of several VR indexes such as cQTd, cJT and Tp-e intervals at the end of CR. (C) 2018 Elsevier Inc. All rights reserved

    The improvement in aerobic capacity, disease activity, and function in patients with rheumatoid arthritis following cardiac rehabilitation program: A single-center, controlled study

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    Objectives: This study aims to evaluate the effect of cardiac rehabilitation (CR) on disease activity, functional status, fitness, and modified cardiovascular disease (CVD) risk factors in patients with rheumatoid arthritis (RA) with a moderate disease activity. Patients and methods: This single-center, controlled study included a total of 60 female RA patients (mean age 57.5 years; range, 50 to 64 years) with moderate disease activity according to the Disease Activity Score-28 (DAS28) between January 2014 and June 2015. The patients were divided into two equal groups as those receiving CR program (n=30) and those receiving home exercise program (HEP; n=30). The patients were evaluated at baseline, at Weeks 10 and 24 using exercise tolerance test (i.e., The Metabolic Equivalent of Task [MET] and maximal oxygen uptake [VO2 max]), Six-Minute Walk Test (6MWT), DAS28, Health Assessment Questionnaire (HAQ), modified Systematic Coronary Risk Evaluation (mSCORE), Short Form Health Survey-36 (SF-36), and Beck Depression Inventory (BDI). Results: There was a significant improvement in the VO2 max (p<0.001), MET (p<0.001), DAS28 (p<0.001), HAQ (p<0.001), BDI (p=0.005), SF-36 physical function (p=0.039), pain (p<0.001) and vitality subscale scores (p=0.008), and 6MWT (p<0.001), after the initial and repetitive exercise programs in the CR group compared to the HEP group. At the end of Week 24, full compliance with HEP was higher in the patients with CR group, compared to the HEP group (p<0.001). There was no significant effect of supervised exercise program on the mSCORE, although systolic blood pressure (p=0.033) and resting heart rate (p=0.049) were significantly improved in the CR group versus HEP group. Conclusion: Based on our study results, supervised exercise program cannot reduce CVD risk as assessed by the mSCORE, although it improves physical fitness, disease activity, and functional outcomes which may reduce traditional CVD risk factors in patients with RA

    Safe Distributed Control of Wireless Power Transfer Networks

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    Wireless power transfer networks (WPTNs) are composed of dedicated energy transmitters (ETs) that charge energy receivers (ERs) via radio frequency waves. A safe-charging WPTN should keep electromagnetic radiation below predetermined limits meanwhile maximizing the transmitted power. In this paper, we consider this requirement as an optimization problem: the maximization of harvested power by ERs subject to the electro-magnetic safety constraints. In order to provide an approximated solution to this problem, we introduce a dual ascent-like distributed charging algorithm that enables ETs to work without global information and satisfy safety constraints asymptotically. We provide an in-depth theoretical analysis of our algorithm which is supported by numerical simulations.Accepted author manuscriptEmbedded System

    Three methods in relation to rate : Described facts in "Sanpou-Tenseihou-Sinan"

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    Let B, A and p be the base quantity, the quantity of be compared and the rate (or proportion), respectively. There are three methods in relation to A, B and p, that is, ・The first method : p = A/B, ・The second method : A = B×p, ・The third method : B = A/p. These three methods are technical terms for teaching. We found description of the three methods in wasan's book : "Sanpou-Tenseihou-Sinan" which was published in the Edo period (1810; Bunka 7). The author of this book is AIDA Yasuaki, who is one of famous mathematicians "wasan-ka". We show the described facts in "Sanpou-Tenseihou-Sinan"

    Simulation based optimization for world line card production system

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    Apak, Sinan (Arel Author), Ercan, Sami (Arel Author)Simulation based decision support system is one of the most commonly used tools to examine complex production systems. The simulation approach provides process modules which can be adjusted with certain parameters by using data relatively easily obtainable in production process. World Line Card production system simulation is developed to evaluate the optimality of existing production line via using discrete event simulation model with variety of alternative proposals. The current production system is analysed by a simulation model emphasizing the bottlenecks and the poorly utilized production line. Our analysis identified some improvements and efficient solutions for the existing system

    "Henry Rider Haggard’s Posthumanist Eco-consciousness"

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    In this essay I argue that the late Victorian and early Edwardian novelist Henry Rider Haggard had a distinct eco-consciousness that was reminiscent of twenty-first century posthumanist philosophies as early as the 1880’s. Writing his “imperial romances” in the wake of the beginnings of what is now called the Anthropocene age, Haggard observed and understood the changing relationships between the human society and the more-than-human world in this historical period. In a manner that would be unexpected of an author widely labeled as ‘a man of his times’—and therefore a pro-imperial propagandist—in postcolonial literary criticism, he was critical of the anthropocentric ways of western civilization. Ranging from a Darwinian notion of the oneness of all living animals to a highly skeptical attitude toward the reckless exploitation of the resources of colonial lands and peoples, Haggard’s Weltanschauung included notions that were not only antithetical to imperialist discourses, but also ‘ahead of [their] times’ by more than a century. In this essay I elaborate on Haggard’s posthumanist eco-consciousness with reference to his fiction and conclude that a renewed understanding of Haggard’s literary and intellectual heritage would show how his works are still very much relevant and valuable in our time

    Dilemma Between Density and Quality: The demographic history of Sinan Road area

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    This paper investigates the unique urban planning history and demographic changes in Sinan Road (also named as Rue Massenet) Area of Shanghai and the socioeconomic impacts on local inhabitants’ living quality led by formal and informal planning dynamics. Examining both tangible and intangible characteristics of this area under five different historical phases, this paper indicates that population density and urban quality cannot always be positively or negatively related. Urban quality can reach the maximum value when area population of concentrated density stays in an ideal state, although, as a result of the qualitative variates, such state (peak value) is in suspense. Through analysing the overarching strategic plan of different periods, it also argues that urban quality is not merely dominated by or directly related to density but more by the population’s social demands and their initial interaction with a specific area, active or passive involvement.History, Form & Aesthetic

    Super Sinan

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    In such design, a simple logic of form appears to be the repetition of inhabitable wall depicting a hybrid system of market, workshop and education, would represent the idea of unity that is required by the position of the site against the fragmented reality. Meanwhile devoted, on a wider level, to reducing the functionality and metaphorical forms of architecture, to an architecture reduced to its barest form – a "typical plan" aimed only at staging the production of everyday life through the most basic architectural practice that has been testified by the "Elementi Primari" of Istanbul. Upon dramatic different scales, it created a various hierarchy space within which where all activities are housed by one simple, consistent architectural gesture. A gesture that stems from the primary elements in the city, faded through time, albeit more pervasive in actuality. "Enciclopedico"Public buildingarchitectureArchitecture and The Built Environmen

    Monodromy of torus fiber bundles and decomposability problem

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    The notion of a (stably) decomposable fiber bundle is introduced. In low dimensions, for torus fiber bundles over a circle the notion translates into a property of elements of the special linear group of integral matrices. We give a complete characterization of the stably decomposable torus fiber bundle of fiber-dimension less than 4 over the circle. (C) 2017 Elsevier B.V. All rights reserved.Mimar Sinan Fine Arts University Scientific Research Projects UnitThis author is partially supported by Mimar Sinan Fine Arts University Scientific Research Projects Unit
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