13,715 research outputs found

    Identification of calretinin and the alternatively spliced form calretinin-22k in primary pleural mesotheliomas and in their metastases

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    Background: Antibodies against calretinin represent an established, powerful and reliable immunohistochemical marker in the differential diagnosis between mesothelioma and adenocarcinomas. However, in studies published so far, the exact molecular identity of the immunoreactive protein(s) detected in mesothelioma sections has not yet been determined. Materials and Methods: Tissue biopsies from ten mesothelioma samples,, primary and metastatic, were analyzed by Western blot analysis and reverse transcriptase-polymerase chain reaction (RT-PCR), in addition to immunohistochemical staining. Results: Besides the selective positive immunoreaction in all 10 samples, calretinin was identified by Western blot analysis and by identification of its mRNA by RT-PCR. In addition, we identified the alternatively spliced form calretinin-22k and the corresponding mRNA, previously detected only in neoplastic cells in colon carcinomas and derived cell lines. Conclusion: Our findings demonstrate that the immunoreactivity observed in the mesotheliomas and their metastases investigated in this report is due to the concomitant presence of calretinin and the alternatively spliced form calretinin-22k

    Mr. Melvin J. Collier, RWWL AUC, June 2011

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    This video is a conversation with Mr. Melvin J. Collier. Mr. Collier talks about his book, "From Mississippi to Africa: A Journey of Discovery". Daniel Le, AUC Woodruff Library, is the interviewer

    Interview Excerpt of Mr. Donald M. Crawford, Sr.

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    (1948-2018) Donald Mitchell Crawford, Sr. (“DC”), musician, author, and educator, was born on May 24, 1948, and was a lifelong resident of Birmingham, AL. His father and mother owned and operated “C & S Charter Tours Bus Company,” the first black-owned bus company in the state of Alabama. Crawford was a 1966 graduate of Western Olin High School in Birmingham, AL. Crawford was an outstanding drum major, playing first chair alto saxophone under the tutelage of the late Amos F. Gordon, Sr. After high school, he received a music scholarship to Alabama State University (ASU) where he earned both his Bachelor’s and Master’s Degrees in Music Education and was later inducted into the “School of Music Hall of Fame” at ASU. He was the youngest ever inducted into the Alabama Jazz Hall of Fame. He was a veteran of the U.S. Army and performed with the 291 st and 283rd Army Band in Fort Bennett, GA. DC was Band Director at Jackson Olin High School and taught in the Birmingham School System for over thirty-five years. His love for music and performing lead him after his retirement to serve as Band Director for Miles College. Crawford is the author of “The Wheels of the Birmingham Civil Rights Movement.” This book chronicles the lives of his late father and mother, Worcy and Christine Pride Crawford, and the role he and the company played in the Birmingham Civil Rights Movement

    Interesting anecdotes, memoirs, allegories, essays, and poetical fragments, [electronic resource] : tending to amuse the fancy, and inculcate morality. By Mr. Addison.

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    Mr. Addison is a pseudonym.On p. 1: Anecdote of Cromwell.Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library

    Interesting anecdotes, memoirs, allegories, essays, and poetical fragments, [electronic resource] : tending to amuse the fancy, and inculcate morality. By Mr. Addison.

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    Mr. Addison is a pseudonym.P. 1 contains an 'Anecdote' beginning "A certain nobleman, .. ".Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library

    Interesting anecdotes, memoirs, allegories, essays, and poetical fragments, [electronic resource] : tending to amuse the fancy, and inculcate morality. By Mr. Addison.

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    Mr. Addison is a pseudonym.On p. 1: Anecdote of Doctor Young.Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library

    Mr Alain Elkann Author and Journalist Italian Republic

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    Visit by Mr Alain Elkann Author and Journalist Italian Republi

    Letter from Misao Miyakawa to Mr. [John Victor] Carson, September 27, 1942

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    This letter acknowledges receipt of an affidavit, presumably for Mikoto Miyakawa, see Items csudh_rsp_0684 and csudh_rsp_0685. The author expresses very sincere gratitude for Mr. Carson's kindness

    To what extent, in the novel ‘The Strange Case Of Dr. Jekyll and Mr. Hyde’ by R. L. Stevenson, the good and evil sides of a man is brought to light by the external (social) and internal (psychological) factors and what are the results of this metamorphosis over the psychology of Dr. Jekyll?

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    Scottish author Robert Louis Stevenson was born in Edinburgh in 1850. Stevenson, besides his authorship, was also a well-known poet and a travel-writer. Today, Stevenson is among the authors whose novels are most translated to other languages in the world . ‘Stevenson's characters often prefer unknown hazards to everyday life of the Victorian society.’1 ‘The Strange Case of Dr Jekyll and Mr Hyde’ by Robert Louis Stevenson, which is accepted as the best novel of the R. L. Stevenson, first published in 1886 and in a real short time sold nearly 40,000 copies in Britain. The mystery of Dr. Jekyll and Mr. Hyde is revealed by the testimonies of Dr. Lanyon, Mr. Utterson, Mr. Enfield, and Poole(Jekyll's butler). One day, with the help of Dr. Jekyll’s will, Mr. Utterson (Jekyll's lawyer), finds out that a stranger, named as Mr. Hyde, is the heir of the Dr. Jekyll's heritage. Mr. Utterson first couldn’t realize the fact behind this weird situation despite his wide research about this stranger and conversations with his friend Dr. Jekyll. However a few witnesses who witnessed this man only mention the irritating evil energy that transpires through his being. First Dr. Jekyll states that Mr. Hyde is simply a close friend of his. Then, when Mr. Hyde is suspected of murder
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