1,721,073 research outputs found

    Replication data for Positive Set of lipidomic data of "PONE-D-24-15462 Untargeted lipidomics reveals unique lipid signatures of extracellular vesicles from porcine colostrum and milk"

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    This set of data presents the positive mass spectrometry data. Details can be found in the manuscript. PONE-D-24-15462 Untargeted lipidomics reveals unique lipid signatures of extracellular vesicles from porcine colostrum and milk. Rafaela Furioso Ferreira, Morteza H. Ghaffari, Fabricio Ceciliani, Manuela Fontana, Donatella Caruso, Matteo Audano, Giovanni Savoini, Alessandro Agazzi, Vladimir Mrljak, and Helga Sauerwei

    Replication data for Negative Set of lipidomic data of "PONE-D-24-15462 Untargeted lipidomics reveals unique lipid signatures of extracellular vesicles from porcine colostrum and milk"

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    This set of data presents the negative mass spectrometry data. Details can be found in the manuscript. PONE-D-24-15462 Untargeted lipidomics reveals unique lipid signatures of extracellular vesicles from porcine colostrum and milk. Rafaela Furioso Ferreira, Morteza H. Ghaffari, Fabricio Ceciliani, Manuela Fontana, Donatella Caruso, Matteo Audano, Giovanni Savoini, Alessandro Agazzi, Vladimir Mrljak, and Helga Sauerwei

    Veterinary Research Communications, Editor of the Special Issue: Clinical Practice Updates in Veterinary Hospitals

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    The aim of this special issue is to provide readers with the latest developments in the field of applied veterinary clinical sciences. This collection focuses on the updates and advancements in daily clinical practices conducted in veterinary hospitals. Scientific articles in this issue will revolve around the management of clinical cases or case series, which will be critically analyzed and discussed in the context of existing scientific literature. Additionally, clinical research activities that have direct implications for veterinary practice will also be considered. Contributions can encompass various aspects of veterinary clinical specialties, across both small and large domestic animals, as well as studies involving unconventional and wild animals including one of the following topics are welcomed: • Internal Medicine • Surgery • Clinical Pathology • Diagnostic Imaging • Reproduction • Emergency • Intensive Care Interdisciplinary reports from interns, PhD students, residents, researchers, as well as other academic and non-academic professionals, are highly encouraged. Original papers and literature reviews, in regular or short article format, will be considered for publication. Prospective authors should send an expression of interest (title and abstract) to the Guest Editors

    Veterinary Research Communications, Editor of the Special Issue: Clinical Practice Updates in Veterinary Hospitals

    No full text
    The aim of this special issue is to provide readers with the latest developments in the field of applied veterinary clinical sciences. This collection focuses on the updates and advancements in daily clinical practices conducted in veterinary hospitals. Scientific articles in this issue will revolve around the management of clinical cases or case series, which will be critically analyzed and discussed in the context of existing scientific literature. Additionally, clinical research activities that have direct implications for veterinary practice will also be considered. Contributions can encompass various aspects of veterinary clinical specialties, across both small and large domestic animals, as well as studies involving unconventional and wild animals including one of the following topics are welcomed: • Internal Medicine • Surgery • Clinical Pathology • Diagnostic Imaging • Reproduction • Emergency • Intensive Care Interdisciplinary reports from interns, PhD students, residents, researchers, as well as other academic and non-academic professionals, are highly encouraged. Original papers and literature reviews, in regular or short article format, will be considered for publication. Prospective authors should send an expression of interest (title and abstract) to the Guest Editors

    MicroRNAs as Biomarkers for Animal Health and Welfare in Livestock

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    MicroRNAs (miRNAs) are small and highly conserved non-coding RNA molecules that orchestrate a wide range of biological processes through the post-transcriptional regulation of gene expression. An intriguing aspect in identifying these molecules as biomarkers is derived from their role in cell-to-cell communication, their active secretion from cells into the extracellular environment, their high stability in body fluids, and their ease of collection. All these features confer on miRNAs the potential to become a non-invasive tool to score animal welfare. There is growing interest in the importance of miRNAs as biomarkers for assessing the welfare of livestock during metabolic, environmental, and management stress, particularly in ruminants, pigs, and poultry. This review provides an overview of the current knowledge regarding the potential use of tissue and/or circulating miRNAs as biomarkers for the assessment of the health and welfare status in these livestock species

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    In vitro assessment of the effects of temperature on phagocytosis, reactive oxygen species production and apoptosis in bovine polymorphonuclear cells

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    Heat stress exerts a direct negative effect on farm animal health, triggering physiological responses. Environmental high temperature induces immunosuppression in dairy cows, increasing the risk of mastitis and milk somatic cell counts. The influence of heat stress on leukocytes activities has not been fully elucidated. The present in vitro study was aimed at assessing whether the exposure to temperature simulating conditions of severe whole body hyperthermia affects defensive functions of bovine blood polymorphonuclear cells. Blood was collected from seven clinically healthy, multiparous, late lactating Holstein cows. After isolation, PMN were incubated at either 39 or 41 °C. Phagocytosis, respiratory burst and apoptosis were then investigated. The selected temperatures of 39 °C or 41 °C mimicked conditions of normothermia or severe heat stress, respectively. Phagocytosis assay was carried out by measuring the fluorescence of phagocyted fluorescein-labelled E. coli bioparticles. The modulation of oxidative burst activity was studied by the cytochrome C reduction method. Apoptosis was determined by measuring the activities of two enzymes that play an effector role in the process, namely Caspase-3 and Caspase-7. Statistical analyses were performed using SPSS 22.0. A Student t-test for paired samples and a Generalised Estimating Equation were used based on data distribution. The phagocytosis rate was reduced (â37%, P < 0.01) when PMN were incubated for 2 h at 41 °C, when compared to phagocytosis rate measured at 39 °C. The oxidative burst, as determined by extracellular production of reactive oxygen species (ROS), was also reduced by the exposure of cells to 41 °C compared to 39 °C. Such reduction ranged between â2 and â21% (P < 0.05). Apoptosis rate was not affected by different temperatures. The results reported in this study suggest that phagocytosis and ROS production in PMN exposed to severe high temperature are impaired, partially explaining the higher occurrence of infections during periods of hot weather
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