1,721,297 research outputs found
Fibrous hamartoma of Infancy: An Italian multi-istitutional experience.
Full text linkFibrous hamartoma of infancy: an Italian multi-institutional experience.
Carretto E, Dall'Igna P, Alaggio R, Siracusa F, Granata C, Ferrari A, Cecchetto G.
Source
Division of Paediatric Surgery, Department of Paediatrics, University of Padua, Padua, Italy.
Abstract
BACKGROUND:
Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative.
OBJECTIVE AND METHODS:
The clinical features and treatment results of 18 children with FH are described.
RESULTS:
Local excision was the most common procedure. Surgery was radical in 10 patients, with microscopic residual disease in 6; all of them are alive with no evidence of disease 2 to 49 months after diagnosis. One patient, treated with a local reexcision for macroscopic residual disease (and chemotherapy for a synchronous desmoid fibromatosis) is well 83 months after diagnosis; the last patient, with a lesion of the labia majora, only underwent biopsy and is doing well, awaiting plastic surgery.
LIMITATIONS:
The results did not reach statistical significance due to difficulties in collecting cases.
CONCLUSIONS:
FH should be treated by complete excision; in our experience a nonradical excision was also able to achieve the cure. An aggressive approach should be avoided, as the overall prognosis is excellent.
PMID:
16635660
[PubMed - indexed for MEDLINE
La genèse d’une culture locale d’entreprise au Nord-Est de l’Italie
No full textEver since the paradigm of “local development” has attained a central position within the regional sciences, the issue of suitable conditions for encouraging the endogenous formation of an entrepreneurial culture has become crucial. These conditions are believed to depend on the presence of a system of values, knowledge and conventions which is favourable to enhancement of an individual spirit of initiative, cooperation inside the local milieu and competition with the outside world: at the same time there must be an institutional system which is geared to encourage fitting individual customs and behaviours.
This book reconstructs the process by which an entrepreneurial culture has risen within a very confined countryside reality, the village of Bessica, in the heart of the Veneto (Italy). Although it remained at the margin of the regional industrialisation process of the 1960s, the village has been the protagonist of a quite original economic development. The marginal situation to which it was initially confined, along with the delay and the peculiarity of its developmental path, offer an exceptional opportunity to examine, in a quasi in vitro situation, the rise and development of a fiercely successful local entrepreneurial community
Micro-imaging in forensic medicine
No full textMicro-radiology has a spatial resolution of a few microns and may be considered the bridge that connects diagnostic imaging and histopathology. The main advantages of micro-radiology techniques, such as micro-computed tomography, micro-magnetic resonance imaging, and ultrasound microscopy are that there is no need for optical transparency in the specimen and imaging is non-destructive. Despite remaining an emerging technology, their use in forensic medicine is growing because they permit the detection of tiny fractures or dislocations of bones, teeth or calcified tissues, the virtual analysis of the micro-architecture of nervous, pulmonary or cardiac tissues, and the 3D reconstruction of the spatial distribution of foreign bodies with a density higher than 1000 HU on the surface or inside biological specimens. In this overview, the prominent areas of practice of micro-imaging methods in the fields of forensic pathology, anthropology and ballistics are illustrated. © Springer International Publishing AG, part of Springer Nature 2017
SURVEY OF THE PRESENCE OF CRYPTOCOCCUS NEOFORMANS AND OTHER PATHOGENIC YEAST IN RACING PIGEONS HOUSES OF NORTHERN ITALY
No full textINTRODUCTION:
Messenger pigeons are domesticated races of Columba livia, bred for they homing ability and used in the past to carry messages;
nowadays these animals are basically used for sport purpose. Pigeon racing is the sport of releasing trained racing pigeons that then
return to their home over a carefully measured distance. In this paper the presence of C. neformans or other potentially pathogenic
yeasts and their relationship with breeding management was investigated in racing pigeon houses from Modena, Bologna and Udine
provinces (Northern Italy).
MATERIALS AND METHODS:
Seventy-three samples of dry pigeon droppings collected from 21 racing pigeon house were analyzed. Mycological analyses were
conducted according to Galuppi et al (2002-6° congresso Nazionale FIMUA Modena, 12-14 settembre 2002). Briefly, two grams of each
specimen were suspended in 10 ml of sterile saline solution with antibiotics (50000 U penicillin, 50000 U streptomycin/100ml of saline)
and stored at 5°C overnight. One hundred microliters of the suspension was then spread, in duplicate, on plates containing Niger Seed
Agar (Shields & Ajello, 1996, Science, 151: 208-209). The plates were incubated at 25°C and 37°C, respectively, for 10 days and daily
observed. The yeasts isolated were identified with Api 20C AUX (Biomerieux Italia S.p.a, Firenze, Italy) and Dalmau plates on Yeast
Morphology Agar DIFCO (Becton Dickinson Italia S.p.a, Milano, Italy).
RESULTS:
Yeasts were isolated from 35 samples incubated at 25°C and from 22 incubated at 37°C. Cryptococcus neoformans was isolated in at
least one samples from 11 pigeon houses (52.4%), Candida guilliermondii in 10 (47.6%), C. albicans in 5 (23.8%), C. famata in 6 (28.5%)
and Rhodothorula sp. in 2 (9.5%). The frequency of isolation of C. neoformans was lower in farms in which disinfection treatment
has been done (46.2%) than in the ones where only mechanical removal were performed (62.5%), but the differences was not
statistically significant. No differences were also observed in relation to different disinfection methods (sodium hypoclorite, steramine
or flame). Vice versa, the daily mechanical removal of feces was significantly related (p<0.05) with a lower frequency of isolation of C.
neoformans, compared to the farms where the removal was performed every 7-15 days (14% vs 71%). No differences were observed
related to treatment or frequencies of mechanical cleaning and the isolation of C. guilliermondii and C. albicans; instead C. famata was
isolated in the 46% of the farms without daily mechanical removal and not found in the other ones (fisher exact<0.05).
CONCLUSIONS:
It is well known as the pigeon’s guano is a source of infectious elements of C. neoformans and is involved in their transmission from the
environment to the humans (Nielsen et al, 2007, Eukariotic cell., 6: 949-959). In the past it has been shown a high seroprevalence of
antibodies against C. neoformans in pigeon fanciers (Walter et al., 1996, J Bacteriol., 92: 82-87), although studies in this regard are very
scarce. In this work it is highlighted as mechanical cleaning decreases the environmental presence of this yeast, whereas the use of
different disinfections methods don’t seems decrease their presence. The daily cleaning and the use of a disposable filtering face mask
could decrease the infection risk in the pigeon fanciers
Approccio chirurgico iniziale al Rabdomiosarcoma (RMS): dati degli Studi del Gruppo Cooperativo Italiano
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Clinical and pathologic considerations in a case of inflammatory myofibroblastic tumor of the spleen
No full textInflammatory myofibroblastic tumors, also called inflammatory pseudotumors, are rare pseudosarcomatous proliferations. Their behavior is generally not aggressive, but in most instances they can simulate malignant neoplasms, from which they are impossible to distinguish before excision. One case of myofibroblastic tumor of the spleen in a 5-year-old boy is described: the patient was treated with a partial splenectomy, which was found to be the best approach for diagnosis and treatment. The purpose of this report is to call attention to this entity with peculiar histologic and immunohistochemical characteristics, which has to be included in the differential diagnosis of splenic lesions and may be excised by a nonaggressive procedure. © Springer-Verlag 2004
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