1,721,292 research outputs found

    POPULARIZING ECONOMICS. TRANSLATIONS, ABRIDGMENTS, AND MINOR WORKS ON MORAL ECONOMY (15TH-16TH CENTURIES)

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    This article explores pre-modern moral economy from an unconventional perspective. Instead of focusing on major thinkers and celebrated texts, it addresses lesser known sources and unoriginal authors, shifting the analysis from the production of economic ideas to their transmission and reception. Two specific domains are targeted. On the one side, an exemplary set of minor and unedited works made of short compositions, abridgments, and collations; on the other, texts deviating from academic canons by writing about moral economy in vernacular instead of Latin. These sources provide insights on how economic vocabularies and conceptualizations developed within the intellectual sphere, when coming into contact with a larger public, were reworked and adapted

    Application of a thermosealing industrial process of packaging to human anatomical prosections in interactive teaching

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    Due to the inability to use cadaver dissection, for both legal and economic reasons [1], in the institute of Human Anatomy of Pavia, we started to use a thermosealing industrial process of packaging (VGP 60 Skin, Orved) to wrap and seal off fixed brains and cranial sections [2]. The purpose of this procedure is to improve students’ preparation in relation to skull osteology and topography of the central nervous system. Designed according to the most demanding hygienic requirements, the “Skin” effect is a packaging system that allows a specific film to adhere perfectly to the sample like a “second skin”, ensuring air-tight packaging with no type of drop and, at the same time, perfect preservation, allowing an excellent visibility too [2]. These preparations, very quick and easy to prepare, are no toxic anymore because lacking of formalin [3] and could be used by medical students to improve their approach to anatomic nervous system structures. First, we have washed brain samples in running water, then frozen to harden and finally sealed. We noted that this strategy largely improved student’s level of exam preparation on human prosectioned speciments in full compliance with the current safety regulations

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Dysbiosis in SARS-CoV-2–infected patients

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    Gastrointestinal symptoms are frequently observed in patients with coronavirus disease 2019 (COVID-19), but only limited knowledge is available regarding the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to influence the host microbiota composition. The entry of SARS-CoV-2 into intestinal cells down-regulates angiotensin-converting 2 receptors and causes microbial dysbiosis.1 , 2 An alteration of the microbial composition may impact the pulmonary defense mechanisms through the so-called gut–lung axis.3 We have read with interest the articles by Zuo et al4 confirming the impact of COVID-19 on the gastrointestinal tract's microbial community composition. Remarkably, their article represents, to our knowledge, the first publication exploring the complex association between SARS-CoV-2 infection and fungi, a neglected component of the gut microbiota. Gut bacteria inhibit the growth of Candida albicans and other gut fungi via the target of rapamycin signaling pathway and through those tryptophan metabolites, which are responsible for an interleukin-22–dependent mucosal response.5 , 6 Bacteria and fungi compete for some nutrients and, in this context, bacteria with probiotic properties may control Candida overgrowth. In healthy volunteers, a commercially available probiotic product has induced a significant fecal anti-Candida activity associated with the augmented production of interferon-alfa in the gastrointestinal tract.7 Another probiotic formulation administered to patients with COVID-19 has induced a significantly faster remission of gastrointestinal symptoms and other symptoms, such as fever, cough, dyspnea, headache, myalgia, and a decreased risk of evolving respiratory failure compared with nontreated patients.8 These preliminary data should encourage the scientific community to investigate the possible use of probiotics in patients with COVID-19, keeping in mind that not all probiotic formulations are equivalent for efficacy and safety in these fragile patients

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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