3,449 research outputs found
The blind spots of secularization
No full textAccording to several international surveys Spain is among the western countries with the most negative views of Jews. While quantitative data on the topic accumulates, there is a significant lack of interpretative approaches that might explain the particular Spanish case. This paper presents the background, methodology and major results of a discussion group-based study on antisemitism, which was conducted in Spain in the autumn of 2009. The study identifies and locates in different socio-economic and ideological milieus the range of stereotypical discourses on Jews, Judaism and the Arab–Israeli conflict in Spain. Analysis of the group meetings shows that, despite growing secularization in Spanish society, the central explanatory variable for persisting and resurging antisemitism in this country is still religion in a broad cultural sense.N
Métricas de autor Alejandro Gómez Jaramillo
No full textInforme de las métricas de autor del Dr. Alejandro Gómez Jaramillo de las publicaciones indexadas en Google Académico cuyo objetivo es entregar un insumo para el fortalecimiento de las capacidades y potencialidades de los autores de la Universidad Santo Tomás en el posicionamiento y visibilidad de sus publicacionesReport of the author metrics Alejandro Gómez Jaramillo of the publications indexed in Google Scholar whose objective is to provide an input for the strengthening of the capacities and potentialities of the authors of the Santo Tomás University in the positioning and visibility of their publications.http://unidadinvestigacion.usta.edu.c
Author response
No full textDetecting pathogens and mounting immune responses upon infection is crucial for animal health. However, these responses come at a high metabolic price (McKean and Lazzaro, 2011, Kominsky et al., 2010), and avoiding pathogens before infection may be advantageous. The bacterial endotoxins lipopolysaccharides (LPS) are important immune system infection cues (Abbas et al., 2014), but it remains unknown whether animals possess sensory mechanisms to detect them prior to infection. Here we show that Drosophila melanogaster display strong aversive responses to LPS and that gustatory neurons expressing Gr66a bitter receptors mediate avoidance of LPS in feeding and egg laying assays. We found the expression of the chemosensory cation channel dTRPA1 in these cells to be necessary and sufficient for LPS avoidance. Furthermore, LPS stimulates Drosophila neurons in a TRPA1-dependent manner and activates exogenous dTRPA1 channels in human cells. Our findings demonstrate that flies detect bacterial endotoxins via a gustatory pathway through TRPA1 activation as conserved molecular mechanism.sponsorship: Vlaams Instituut voor Biotechnologie Alessia Soldano Luis Franco Guangda Liu Natalia Mora Emre Yaksi Bassem A Hassanr Fonds Wetenschappelijk Onderzoek G.0702.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0077.15 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0680.10 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0681.10 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0503.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0654.15 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0761.10N Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0596.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0565.07 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar KU Leuven GOA/14/011 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar European Commission IUAP P7/13 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekensr KU Leuven OT/12/091 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar KU Leuven PF-TRPLe Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talavera (Vlaams Instituut voor Biotechnologie, Fonds Wetenschappelijk Onderzoek|G.0702.12, Fonds Wetenschappelijk Onderzoek|G.0077.15, Fonds Wetenschappelijk Onderzoek|G.0680.10, Fonds Wetenschappelijk Onderzoek|G.0681.10, Fonds Wetenschappelijk Onderzoek|G.0503.12, Fonds Wetenschappelijk Onderzoek|G.0654.15, Fonds Wetenschappelijk Onderzoek|G.0761.10N, Fonds Wetenschappelijk Onderzoek|G.0596.12, KU Leuven|GOA/14/011, KU Leuven|OT/12/091, European Commission|IUAP P7/13, KU Leuven PF-TRPLe)status: Publishe
Characterization of Viscoelastic Media Combining Ultrasound and Magnetic-Force Induced Vibrations on an Embedded Soft Magnetic Sphere
No full text[EN] We report a method to locally assess the complex shear modulus of a viscoelastic medium. The proposed approach is based on the application of a magnetic force to a millimeter-sized steel sphere embedded in the medium and the subsequent monitoring of its dynamical response. A coil is used to create a magnetic field inducing the displacement of the sphere located inside a gelatin phantom. Then, a phased-array system using 3 MHz ultrasound probe operating in pulse-echo mode is used to track the displacement of the sphere. Experiments were conducted on several samples and repeated as a function of phantom temperature. The dynamic response of the sphere measured experimentally is in good agreement with Kelvin¿Voigt theory. Since the magnetic force is not affected by weak diamagnetic media, our proposal results in an accurate estimation of the force acting on the inclusion. Consequently, the estimated viscoelastic parameters show excellent robustness and the elastic modulus agrees with the measurements using a quasi-static indentation method, obtaining errors below 10% in the whole temperature range. The use of the macroscopic inclusion limits the direct application of this method in a biomedical context, but it provides a robust estimation of the elastic modulus that can be used for material characterization in industrial applications.This work was supported in part by the Spanish Ministry of Science, Innovation and Universities through the "Juan de la Cierva - Incorporacion" under Grant IJC2018-037897-I, in part by the Program "Proyectos I+D+i 2019" under Grant PID2019-111436RB-C22, in part by the Agencia Valenciana de la Innovacio under Grant INNCON/2021/8, in part by Generalitat Valenciana under Grant AICO/2020/268, and in part by the European Union through the Programa Operativo del Fondo Europeo de Desarrollo Regional (FEDER) of the Comunitat Valenciana 20142020 under Grant IDIFEDER/2018/022. The work of Alejandro Cebrecos was supported by the Universitat Politecnica de Valencia under Program PAID-10-19.Cebrecos, A.; Jimenez, N.; Tarazona Tárrega, R.; Company, M.; Benlloch Baviera, JM.; Camarena Femenia, F. (2021). Characterization of Viscoelastic Media Combining Ultrasound and Magnetic-Force Induced Vibrations on an Embedded Soft Magnetic Sphere. IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control. 68(12):3540-3548. https://doi.org/10.1109/TUFFC.2021.3097883S35403548681
Alma, impulso y movimiento según Alejandro de Afrodisia
No full textthis paper discusses Alexander of Aphrodisias’ conception of the soul, paying special attention to a specific aspect distinguishing the Alexandrian view from the Aristotelian one: the impulsive capacity or faculty. Firstly, it considers Alexander’s reformulation of Aristotle’s approach to the soul (as a form of the body), a reformulation that is performed in connection with his original reconstruction of hilemorphism. At this point the author makes a special emphasis upon the manner Alexander develops a ‘terraced model’ of hilemorphic composition. Secondly, the treatment of impulsive faculty, with a special focus on the theoretical performance that Alexander derives from taking the notion of impulse, is developed. Finally, Alexander’s reformulation of the Aristotelian psychology of action is also brie y considered in order to account for the sequence of the process of the production of voluntary movement and of action. This is an explicative model that leaves aside the Aristotelian resource to the structure of the practical syllogism, and incorporates the elements predominantly characteristic of the Stoic conception. This, though, does not entail the abandonment of the basic thesis of Aristotle’s stance regarding motivation, as an opposition to socratic intellectualism: the thesis of the primacy of desire, in all its possible ways, as a factor accounting for the origin of voluntary movement and action.Este artículo se ocupa de la concepción del alma elaborada por Alejandro de Afrodisia, con especial atención a un aspecto específico que la distingue de la concepción aristotélica: la introducción de una facultad o capacidad impulsiva. En primer lugar, se considera la reformulación de la concepción jaristotélica del alma como forma del cuerpo que Alejandro lleva a cabo, en conexión con su original reconstrucción del hilemorfismo. Aquí se pone especial énfasis en el modo en el cual Alejandro construye lo que puede llamarse un “modelo escalonado” de composición hilemórfica. En segundo lugar, se considera el tratamiento de la facultad impulsiva, atendiendo especialmente al rendimiento teórico que extrae Alejandro de la adopción de la noción de impulso. Por último, se considera brevemente el modelo reformulado de psicología de la acción que elabora Alejandro, para dar cuenta de la secuencia del proceso de producción del movimiento voluntario y la acción. Se trata de un modelo explicativo que deja de lado el recurso aristotélico a la estructura del silogismo práctico e incorpora, en cambio, los elementos más característicos de la concepción estoica. Ello no implica, sin embargo, el abandono de la tesis básica de la concepción aristotélica de la motivación, por oposición al intelectualismo socrático, a saber: la tesis de la primacía del deseo, en todas sus posibles formas, como factor que da cuenta del origen del movimiento voluntario y la acción
Author-level metrics. Technical Manual. 2.0 Version
No full textBecerril-García, Arianna, Aguado-López, Eduardo, & Macedo-García, Alejandro. (2023). Author-level metrics. Technical Manual. Zenodo. https://doi.org/10.5281/zenodo.79165
Low-cost photoacoustic microscopy for non-invasive imaging of dermatologic diseases
No full text[EN] Photoacoustic imaging has emerged over the last two
decades as a promising tool for the early diagnosis of dermatologic diseases in a rapid and non-invasive manner.
However, it is necessary to develop new techniques to reduce its cost and make it accessible in dermatologic clinics and primary care centers. In this paper, we explore
some of the current applications of this technique in the
field of dermatology. Also, we describe our progress in the
development of a portable prototype of low-cost photoacoustic microscopy for volumetric imaging of melanoma.[ES] La imagen fotoacústica ha surgido durante las dos últimas décadas como una herramienta prometedora para
el diagnóstico precoz de enfermedades dermatológicas de
forma rápida y no invasiva. No obstante, resulta imprescindible avanzar en el desarrollo de técnicas que permitan
reducir su coste para hacerla así accesible en consultas
dermatológicas y centros de atención primaria. En este
trabajo, exploramos algunas de las aplicaciones actuales
de esta técnica en el campo de la dermatología. Además,
describimos los avances de nuestro equipo en el desarrollo de un prototipo portátil de microscopía fotoacústica de
bajo coste para imagen volumétrica de melanoma.Agradacemos el soporte de financiación a través de los programas de convocatorias competitivas: Agència Valenciana de la Innovació (AVI) a través del proyecto INNVA1/2022/50, Programa Investigo INVEST/2022/171 de fondos de la Unión Europea Next Generation EU, y
también, Prometeo CIPROM/2021/003 y Equipamiento e Infraestructuras FEDER 2021-22 IDIFEDER/2021/004Navarro-Calvo, Javier Ángel;García-Garrigos, Juan José;Cebrecos, Alejandro;Marco-Jiménez, Francisco;Camarena Femenia, Francisco (2024). Microscopía fotoacústica de bajo coste para imagen no invasiva de enfermedades dermatológicas. Revista de Acústica (Online). 55(3 y 4):3-10. https://riunet.upv.es/handle/10251/228967S310553 y
A fiber-coupled laser diode design for reflection mode optical resolution photoacoustic microscopy
No full text[EN] Pulsed Laser Diodes (PLD) are compact and high pulse repetition rate laser sources that show a great potential for low-cost Optical Resolution Photoacoustic Microscopes (OR-PAM). Nevertheless, their non-uniform multimode laser beams are of low quality so that high lateral resolutions with tightly focused beams are difficult to realize at long focusing distances, as required for reflection mode OR-PAM devices of clinical application. A new strategy based on homogenizing and shaping the laser diode beam with a square-core multimode optical fiber allowed to attain competitive lateral resolutions while keeping one centimeter working distance. The theoretical expressions for the laser spot size, determining optical lateral resolution, and the depth of focus are also written for general multimode beams. An OR-PAM system was built in confocal reflection mode with a linear phased-array as the ultrasound receiver in order to test its performance, first, on a resolution test target and, afterwards, on ex vivo rabbit ears to show the system potential for subcutaneous imaging of blood vessels and hair follicles.We are grateful for financial support from Agencia Estatal de Investigacion, Spain (PID2019-111436RBC22/AEI/10.13039/50110001 1033), Generalitat Valenciana, Spain through the programs Equipamiento e Infraestructuras FEDER 2021-22 IDIFEDER/2021/004, Prometeo CIPROM/2021/003 and Programa de Garantia Juvenil I+D EDGJID/2021/189, Agencia Valenciana de la Innovacio INNVA2/2022/11 and INNVA1/2022/50, and the European Union - Next GenerationEU Programa Investigo INVEST/2022/171. A. Cebrecos is grateful for financial support from Universitat Politecnica de Valencia, Spain through pro-grams PAID-10-19 and Ayuda para potenciar la investigacion postdoc-toral de la UPV PAID-PD-22.García-Garrigós, JJ.; Cebrecos, A.; Navarro-Calvo, JA.; Camarena Femenia, F. (2023). A fiber-coupled laser diode design for reflection mode optical resolution photoacoustic microscopy. Ultrasonics. 132. https://doi.org/10.1016/j.ultras.2023.107008S13
Cómo vamos a vivir juntos?
No full textThis book by Alejandro Aravena explores the critical question of coexistence in modern societies, particularly in the context of urban planning, social participation, and the collective challenges we face in the 21st century. The book originates from a keynote speech given by the author at the Chilean Constitutional Convention in 2021, where he reflected on the future of society and urban development over the next century.
Drawing from his extensive experience in architecture and participatory design, Aravena presents key lessons learned through real-world projects and community engagement. These principles emphasise the importance of inclusive urban planning, equitable resource distribution, and the balance between regulation and self-regulation. The book argues that solving complex social issues requires more than just good intentions. It demands a deep understanding of diverse perspectives and a willingness to embrace dialogue and collaboration.
A central theme is the idea that neither the market nor the state alone can provide sustainable solutions for urban and social challenges. Instead, the book advocates for a "third way" that trusts in people's agency, acknowledging their role as active contributors to the built environment rather than passive recipients of top-down policies. The text highlights the need to shift from mere tolerance to genuine admiration for cultural diversity, particularly in the context of the Chilean-Mapuche relationship. To this aim, the author explores the potential of indigenous knowledge, historical negotiation practices, and the power of storytelling in shaping a shared future.
By blending architectural insight with sociopolitical analysis, this book serves as a manifesto for collective responsibility, urging readers to rethink how cities, policies, and communities can be designed to foster sustainable and harmonious living conditions
Review book Alejandro Herrero
No full textThe work entitled “From the United Provinces to the Argentine Nation. An approach”, by the author Alejandro Herrero, consists of six chapters and a documentary appendix that has six documents. In the first instance, the writing itself unfolds in a reinterpretation of the origins of nationalities. He maintains that in the Argentine Republic, nationality does not come from the national State directly, but rather they have different historical moments
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