1,720,960 research outputs found
Microfluidic Platform for Microalgae Cultivation under Non-limiting CO2 Conditions
Microfluidic platforms for microalgae cultivation can be exploited to intensify data collection and enhance the ability to control the most relevant operational parameters. In this work, a new array of micro-photobioreactors (mPBR) was designed to supply a continuous flow of nutrients; CO2 is the main substrate for photosynthesis, but its supply in nonlimiting concentration to microdevices can represent a design challenge. To address this issue, a preliminary CO2 absorption phase was exploited. This carbon-rich liquid stream was then delivered to the mPBR, where it diffused to the culture wells. The device was tested with Scenedesmus obliquus using in vivo chlorophyll fluorescence measurements for growth monitoring. Results demonstrated that the experimental setup is effective at delivering CO2 inside the mPBR. Tests at different incident light intensities showed the mPBR applicability to describe light effects on cell growth, without carbon and nutrient limitations and undesired self-shading effects
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Analisi d'immagine multivariata per la stima della concentrazione microalgale in micro-fotobioreattori
L'analisi d'immagine multivariata è stata impiegata per sviluppare un nuovo metodo per monitorare la crescita della biomassa microalgale, dato che le tecniche analitiche tradizionali non possono essere applicate a micro-fotobioreattori.ope
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
A model‐based protocol for the diagnosis of von Willebrand disease
Von Willebrand disease (VWD) is one of the main inherited coagulation disorders. It is caused by a deficiency and/or a dysfunction of the von Willebrand factor (VWF), a fundamental multimeric glycoprotein involved in the hemostasis process. Correct detection of the disease is not an easy task because the disease manifests itself in many variants and a high intra-subject variability is observed. For these reasons, the diagnostic clinical trials typically rely on a 24-h sampling protocol, which makes the overall test long, stressful, and costly. Using a new pharmacokinetic model derived from Galvanin et al.'s 2014 study, this study aims at i) assessing the theoretical possibility to perform a shorter clinical test and ii) proposing a set of model-based diagnostic methods as a support for the clinical team. A preliminary information analysis is performed in order to understand which sampling instants are more informative for model identification. This allowed us to propose a novel, 8-h diagnostic protocol, which is still able to ensure model identifiability. Three alternative diagnostic methods are then proposed based on this short-length clinical protocol. One of them directly uses the pharmacokinetic model, whereas the other two are based on the use of three indices (two pharmacokinetic indices, namely clearance, total VWF released, and as third index the basal multimer ratio) to formulate the diagnosis problem as a classification one. The classification problem is then solved using K-nearest neighbours and linear discriminant analysis. Results show the theoretical feasibility of a VWD diagnosis based on a shorter protocol
Development of a model-based approach to the characterization and diagnosis of type 1 von Willebrand disease
Von Willebrand disease (VWD) is the most common inherithed bleeding disorder and it is caused by a deficiencies of von Willebrand factor (VWF), which is a glycoprotein fundamental in the coagulation process. Type 1 is the most common VWD variant; through the clinical data and a pharmacokinetic model, an algorithmic approach supporting the diagnosis of type 1 VWD is proposed.ope
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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