138 research outputs found

    Süt sektöründe toplam kalite ve İSO uygulamaları

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    Turhan, İlkay (Arel Author) --- 8. Gıda Mühendisleri Kongresi, Ankara, 7-9 Kasım 2013.

    Changes in Antimicrobial Resistance of Urinary Tract Infections in Adult Patients over a 5-Year Period

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    Vahaboglu, H/0000-0001-8217-1767; Culpan, Meftun/0000-0001-8573-1192; caskurlu, hulya/0000-0002-6760-2052Objectives: We aimed to determine the most common bacteria that cause urinary tract infections (UTIs), the rate of antibiotic resistance of these uropathogens, and the changes in resistance rates over the years for adult patients diagnosed with UTIs. Methods: We retrospectively reviewed urine cultures and antibiotic susceptibility results of patients >17 years of age from our outpatient clinic between 2014 and 2018. The most common uropathogens and their antibiotic resistance rates were identified in different age groups (18-39, 40-59, and >= 60 years) and with respect to gender and date of admission. In addition, the change in antibiotic resistance of Escherichia coli between 2014 and 2018 was also examined. Results: A total of 9,556 positive urine cultures were included. The most common uropathogen was E. coli, and its prevalence was higher in females than males (70.6 vs. 53.4%, respectively). The majority of isolates were from patients >= 60 years of age. E. coli resistance was most pronounced for ampicillin (61.56%), followed by trimeth-oprim-sulfamethoxazole (49.80%), amoxicillin-clavulanic acid (34.69%), and cefazolin (30.72%). E. coli resistance to ampicillin, nitrofurantoin, cefepime, ciprofloxacin, fosfomycin, and amoxicillin-clavulanic acid increased significantly with time (all p = 0.001). For E. coli, resistance to ciprofloxacin, one of the most commonly used antibiotics for UTI, increased from 17 to 43% from 2014 to 2018. Conclusion: Most of the uropathogens displayed high resistance to ampicillin, tri-methoprim-sulfamethoxazole, and amoxicillin-clavulanic acid, and were susceptible to meropenem, ertapenem, and imipenem. Fosfomycin and cefepime were useful in the empirical treatment of community-acquired UTIs. A surprisingly high increase was observed in the resistance of E. coli to antimicrobial agents from 2014 to 2018

    Calculation of NOx Emissions of Short and Medium-haul Domestic Flights with Consideration of the Ambient Effect

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    8th International Conference on Mechanical and Aerospace Engineering (ICMAE) -- JUL 22-25, 2017 -- Prague, CZECH REPUBLICWOS: 000427156200079In this study, NOx emissions of typical flights at two domestic round trip routes (206-271 NM and 625-740NM) are quantified. The flight and engine parameters were obtained from actual flight data records, whereas the emission index of sea level NOx was obtained from the emission database of the International Civil Aviation Organization for a specific type of engine. Using the Boeing Fuel Flow Method 2 for altitude correction, the total flight NOx emissions are found to be on average 66.2 kg for short and 152.2 kg for medium flight distance, showing a NOx per kilometer of between 0.32 and 0.21 g/km. The fraction of landing and takeoff NOx emissions changes between 17.2% and 10.0% on average, depending on flight distance. The average total flight NOx emission per kg fuel burned is calculated to be 31-32 g/kg fuel. When a constant relative humidity is assumed as 60% during an entire flight, the total NOx emissions is found to be up to 12.1 kg lower than for those where the relative humidity depends on altitude.IEEEScientific and Technological Research Council (TUBITAK) [111Y048]; Anadolu University Scientific Research Project Commissions of Turkey [1205F091]This study was supported by the Scientific and Technological Research Council (TUBITAK) (Project No: 111Y048) and Anadolu University Scientific Research Project Commissions (Project No: 1205F091) of Turkey. The author gratefully acknowledges Turkish Airlines (THY) as a partner in the projects, allowing access to actual flight data

    Effects of Ambient Air Temperature on Gaseous Emissions of Turbofan Engines

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    WOS: 000376672600018This study presents the results of analyses related to the effects of ambient air temperature (ranging from 5.2 to 23.9 degrees C) on certain engine performance parameters and gaseous emissions, carbon monoxide and nitrogen oxides. The data set used in the analyses was developed from gaseous-emission measurements of aircraft turbofan engines, during routine test-cell operations after overhauls. The engine focused on is the CFM56-7B26. Because the data were recorded in a continuous manner, all of the parameters have been characterized throughout the operations between idle to takeoff power. Two important parameters, combustion efficiency and specific fuel consumption, are also identified for all of the power settings, and are used to evaluate the effects of ambient air temperature on emissions. The results suggest that ambient air temperature is negatively correlated with thrust and pressure ratios, whereas it is positively correlated with exhaust-gas and combustor-inlet temperatures. In addition, the effects of ambient air temperature on thrust, combustor-inlet pressure, and overall and high-pressure compressor pressure ratios are higher at higher power settings than at lower power settings. Furthermore, the higher the ambient air temperature is, the higher are the combustion efficiency and specific fuel consumption, particularly at low power settings. At ground-idle power settings, the specific fuel consumption is found to be 41 and 24 g/kNs for above and below 14.0 degrees C of ambient air temperature. The nitrogen oxides results are generally found to be lower than the International Civil Aviation Organization nitrogen oxides values, and the results point out, as anticipated, a tendency toward higher nitrogen oxides at higher ambient air temperatures. Carbon monoxide emissions at low power settings are found to be highly variable compared to those for the International Civil Aviation Organization values, due to the fact that the carbon monoxide emissions are strong functions of engine power at low power settings, and any difference in engine power leads to substantial differences in carbon monoxide emissions. Therefore, this difference is addressed to the difference in idle power assumption of the International Civil Aviation Organization. The effects of ambient air temperature on carbon monoxide emissions also suggest a negative correlation, particularly at low power settings, whereas it is not as discernible as with the nitrogen oxides emissions.Scientific and Technological Research Council (TUBITAK) of Turkey [111Y048]; Anadolu University Scientific Research Project Commissions of Turkey [1205F091]; Turkish Airlines; Turkish Technic, Inc.This study was supported by the Scientific and Technological Research Council (TUBITAK) (project number 111Y048) and the Anadolu University Scientific Research Project Commissions (project number 1205F091) of Turkey, in partnership with Turkish Airlines and Turkish Technic, Inc. The author thanks Lead Engineer Mehmet Gungor, operational fuel manager Resat Gunduz, and the staff of the test cell (Mehmet Ucarsu, Cemil Ovacik, Cetin Nogan, Ersin Gokdemir, I. Volkan Kadioglu, and Sevdar Ozkan) for providing the necessary installations and for many useful discussions

    Occurrence of aflatoxin B1, total aflatoxin and ochratoxin a in bulgur commercialized in Turkey

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    #nofulltext# --- Turhan, İlkay (Arel Author), Büyükünal, Serkan Kemal (Arel Author), Şakar, Fitnat Şule (Arel Author) --- Conference : II International VETistanbul Group Congress. DIGEST : Saint-Petersburg, Russia, 07-09 April 2015.Mycotoxins are important fungal toxic secondary metabolites with regards to food safety. They are formed during cereal growth or in post-harvest storage and they may not be completely removed during food processing operations. Mycotoxins have carcinogenic, mutagenic, teratogenic, toxicological effects on humans and animals. In this study, totally 113 bulgur samples were investigated for the levels of afl atoxin B1 (AFB1), total afl atoxin (AF Total) and ochratoxin A (OTA) by ELISA technique. AFB1 levels were between 0-1 ppb in 61 samples (53.98 %), between 1.001-1.999 ppb in 52 samples (46.02 %). AF Total levels were between 0-1 ppb in 20 samples (17.70 %), between 1.001-1.999 ppb in 46 samples (40.71 %), between 2-2.999 ppb in 39 samples (34.51 %) and between 3-3.999 ppb in 8 samples (7.08 %). OTA levels were between 0-1 ppb in 69 samples (61.06 %), between 1.001-1.999 ppb in 35 samples (30.98%), between 2-2.999 ppb in 6 samples (5.31 %) and above 3 ppb in 3 samples (2.65 %). These three bulgur samples were contaminated at levels above the legal limit (max 3 ppb) for ochratoxin

    The role of serum testosterone to prostate-specific antigen ratio as a predictor of prostate cancer risk

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    AbstractWe analyzed the ratio of serum total testosterone (sTT) to prostate-specific antigen (PSA) as a predictor of prostate cancer risk. One-hundred-four consecutive men with a normal digital rectal examination and a serum PSA level of 2.5–10 ng/ml underwent transrectal ultrasonography-guided biopsy using a 10-core scheme. The sTT level was determined before the procedure using a chemiluminescent assay, and the ratio of sTT to PSA (sTT/PSA) was calculated after transforming sTT measurements from ng/dL to ng/mL. The overall cancer detection rate was 17.3%. The median sTT level was 332 ng/dl in men with cancer and 413 ng/dL in those without (p = 0.032). The median sTT/PSA ratio in these groups was 0.55 and 0.74, respectively (p = 0.035). The receiver operator characteristic (ROC) method was used to evaluate the properties of the sTT/PSA ratio, with testosterone and PSA as predictors of prostate cancer risk. The accuracy of the sTT/PSA ratio in prostate cancer diagnosis, represented by the area under the curve (AUC), was 0.739 (95% CI 0.640–0.823, p < 0.05). Optimizing the sensitivity and specificity of the sTT/PSA ratio using the ROC provided a cutoff point of 0.60, which corresponded to 82% sensitivity and 62% specificity. When the patients were divided into normal- and low-sTT level groups according to testosterone value (300 ng/dl), the probability of detecting prostate cancer was 3.3-fold higher in hypogonadal men as compared with eugonadal men. These results support the use of the sTT-to-PSA ratio for predicting the risk of prostate cancer and increasing the specificity of PSA measurement

    Geleneksel bir gıda olarak ilkme yoğurdunun mikrobiyolojik ve kimyasal özellikleri

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    Turhan, İlkay (Arel Author). --- #nofulltext# --- Conference: 4.Gelenelsel Gıdalar Sempozyumu, Adana, 17-19 Nisan 2014.İlkme yoğurdu Denizli’nin Acıpayam ilçesinde eskiden beri yapılan, günümüzde kolay fabrikasyon üretimi tercihleri nedeniyle unutulmaya yüz tutan geleneksel bir üründür. İlkme yoğurdu küpeç denilen toprak kaba süt, yoğurt (maya olarak) ve tuz karışımının ilave edilmesi, ham yoğurdun oluşumunun ardından kap içine 2-3 günde bir süt eklenmesi, altta oluşan suyun atılması ve bu yapının bir ay boyunca güneşte mayalanmasıyla üretilen zahmetli fakat bir o kadar da sağlıklı ve lezzetli bir gıdadır. Bir aylık olgunlaşma süreci sonunda yoğurt yenecek tat ve kıvama ulaşır. Bu çalışmada belirtilen şekilde ev koşullarında üretilen ilkme yoğurtlarının (3 adet) mikrobiyolojik ve kimyasal analizleri yapılarak kalite kriterleri araştırılmıştır. Örneklerde ortalama olarak toplam mezofilik aerop bakteri 2,74 ile 4,58 log kob /g, Lactococcus sp. 2,89 ile 8,05 log kob/g, Lactobacillus sp 3,16 ile 7.98 log kob/g, maya- küf 2,32 ile 7,75 log kob/g, koliform grubu 2,51 ile 7,24 log kob/g olmak üzere oldukça geniş bir aralıkta değiştiği tespit edilmiştir. Kimyasal olarak asitlik, yağ, kuru madde, kül, protein ve tuz tayinleri gerçekleştirilmiştir. Geleneksel bir ürün olarak ilkme yoğurdunun kimyasal ve mikrobiyolojik açıdan standart yoğurt özelliklerinden oldukça farklı kriterlerde olması, endüstride ve geleneksel olarak üretilen süt ürünlerinden oldukça farklı bir üretim metoduna sahip olmasından kaynaklandığı düşünülmektedir

    Is there a relationship between severity of coronary artery disease and severity of erectile dysfunction?

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    Introduction The correlation between erectile dysfunction (ED) and coronary artery disease has been emphasized and ED has been recognized as a potential independent risk factor and/or predictor of coronary artery disease (CAD). We evaluated the association between the number of occluded coronary arteries in myocardial infarction (MI) patients with the severity of ED, and investigated the influence of related risk factors in our study group. Materials and Methods 183 male patients who underwent coronary angiography because of acute MI from November 2009 to May 2011 were included. Following the stabilization of patients after the treatment, each patient was evaluated for erectile functionality. Risk factors such as age, diabetes, smoking, waist circumference, hypertension, and hematologic parameters were recorded. Results Among 183 patients with a mean age of 55.2 years who underwent coronary angiography due to acute MI, 100 (54.64%) had ED, while the ED rate was 45.36% (44/97) in cases of single-vessel disease, 64.5% (31/48) in cases of two-vessel disease, and 65.7% (25/38) in cases of three-vessel disease. The mean IIEF score was 24.2 ± 4.3, 20.4 ± 4.9 and 20.5 ± 4.2 for single or two or three-vessel disease, respectively. The presence of hypertension aggravated ED only in patients with three-vessel disease and increased total and LDL cholesterol levels in patients with single-vessel or two-vessel disease were accompanied by significantly decreasing IIEF scores. Conclusion The severity of ED correlated with the number of occluded vessels documented by coronary angiography, in male patients with acute myocardial infarction. In addition, the presence of hypertension had a significant influence over erectile function only in patients with three-vessel occlusion
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