1,721,001 research outputs found
Clinical and pathological findings of acute zinc intoxication in a puppy
No full textThis report describes the clinical and pathological findings in a case of acute zinc poisoning in a young dog. The puppy suffered four days of progressively more severe vomiting and diarrhoea. Jaundice and pale mucous membranes, severe haematemesis and haemoglobinuria were other findings. Despite intensive therapy, the dog died a few hours after hospitalisation. Postmortem examination revealed a metallic foreign body in the stomach, catarrhal gastritis, hepatomegaly and enlarged, dark kidneys. Histology showed hepatic centrilobular vacuolar degeneration, haemoglobinuric nephrosis with early tubular necrosis, haemosiderosis and extramedullary haematopoiesis, as well as neuronal damage. The foreign body was mainly composed of zinc. Plasma zinc values were markedly raised (34-5 Mg/ml; normal range 0-8 to 1-0 μg/ml). Pathophysiological mechanisms of zinc poisoning are discussed
RESPONSES OF LIVER-ENZYMES TO CADMIUM ADMINISTRATION IN THE GOLDFISH (CARASSIUS-AURATUS) AT DIFFERENT TIMES OF THE YEAR
No full textThe activity of goldfish liver ornithine and adenosylmethionine decarboxylase increased upon cadmium chloride injection in April and November. Liver metal concentration increased after the injection and hepatic metallothionein was induced at all times independently of the responses of the two enzymes
Site-specific symmetry sensitivity of angle-resolved photoemission spectroscopy in layered palladium diselenide
Full text linkTwo-dimensional (2D) materials with puckered layer morphology are promising candidates for next-generation optoelectronics devices owing to their anisotropic response to external perturbations and wide band gap tunability with the number of layers. Among them, palladium diselenide (PdSe2) is an emerging 2D transition-metal dichalcogenide, with a band gap ranging from ∼ 1.3 eV in the monolayer to a predicted semimetallic behaviour in the bulk. Here, we use angle-resolved photoemission spectroscopy to explore the electronic band structure of PdSe2 with energy and momentum resolution. Our measurements reveal the semiconducting nature of the bulk. Furthermore, constant binding-energy maps of reciprocal space display a remarkable site-specific sensitivity to the atomic arrangement and its symmetry. Supported by density functional theory calculations, we ascribe this effect to the inherent orbital character of the electronic band structure. These results not only provide a deeper understanding of the electronic configuration of PdSe2, but also establish additional capabilities of photoemission spectroscopy
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Multiple scattering X-ray absorption studies of Zn 2+ binding sites in bacterial photosynthetic reaction centers
No full textEffects of waterborne Cu exposure in gilthead sea bream (Sparus aurata): A proteomic approach
No full textAquatic organisms may suffer from exposure to high Cu concentrations, since this metal is widely used in feed supplementation, in pesticide formulation and as antifouling. Chronic exposure to Cu, even at sub-lethal doses, may strongly affect fish physiology. To date, several biomarkers have been used to detect Cu exposure in fish producing contrasting results. Therefore, we used a proteomic approach to clarify how Cu exposure may affect the serum proteome of gilthead sea bream (Sparus aurata), since serum could be considered a good source of early-biomarkers of Cu toxicosis. For this purpose we exposed juvenile gilthead sea bream to waterborne Cu (0.5 mg/L). Our results indicate that fish tightly regulate circulating Cu levels, which are not affected by metal exposure. This homeostatic control is mainly achieved by the liver, able to excrete high amounts of the metal via bile. Cu exposure caused differential expression of several serum proteins, 10 of which were identified by Mascot and BLAST search. All these proteins, with the exception of growth hormone receptor and γ-glutamyl-carboxylase, can be related to: 1) Cu-induced hepatotoxicity (cytochrome oxidase subunit I, alanine aminotransferase, glutathione S-transferase); 2) potential immunosuppression due to interference of Cu with the inflammation/immunity network (α-1 antitrypsin, angiotensinogen, complement component C3, recombination-activating protein-1 and warm temperature acclimation-related 65 kDa protein). © 2011 Elsevier Ltd
RESPONSES OF POLYAMINE METABOLISM TO METAL TREATMENT (CO, CU, ZN, CD) IN THE LIVER OF THE GOLDFISH (CARASSIUS-AURATUS) - DISTINCT EFFECT OF SEASON AND TEMPERATURE
No full text1. Cobalt, copper, zinc and cadmium injected into Carassius auratus in April (water temperature 16-degrees-C) increased liver ornithine decarboxylase and adrenosylmethionine decarboxylase and not tyrosine aminotransferase activities independently of their accumulation within the liver. 2. As previously shown, cadmium stimulated ornithine decarboxylase in November (16-degrees-C), but was ineffective in July (23-degrees-C). 3. Acclimation of fish at 23-degrees-C in April and November caused the metal to become ineffective, but acclimation at 15-degrees-C in July failed to restore the response to cadmium. 4. In February no significant changes occurred either at 14-degrees-C or at 23-degrees-C with any of the metals. 5. Putrescine and polyamine concentrations essentially followed the response of ornithine decarboxylase activity
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